A large C-terminal Rad52 segment acts as a chaperone to Form and Stabilize Rad51 Filaments by Emilie Ma, Fadma Lakhal, Eleni Litsardaki, Myriam Ruault, Maxime Audin, Natacha Levrier, Emilie Navarro, Mickaël Garnier, Laurent Maloisel, Jordane Depagne, Clémentine Brocas, Aurelien Thureau, Didier Busso, Xavier Veaute, Raphaël Guerois, Angela Taddei, Françoise Ochsenbein, Eric Coïc

“…Notably, it includes an FxxA motif conserved in the BRC repeats of BRCA2 and at the Rad51-Rad51 interface. This binding mode was validated through an extensive set of mutations. …”
Get full text

An integrated machine learning model of transcriptomic genes in multi-center chronic obstructive pulmonary disease reveals the causal role of TIMP4 in airway epithelial cell by Erkang Yi, Haiqing Li, Yu Liu, Qingyang Li, Chengshu Xie, Ruining Sun, Fan Wu, Zhishan Deng, Kunning Zhou, Hairong Wang, Xinru Ran, Yumin Zhou, Pixin Ran

“…In primary human airway epithelial cells cultured at the air-liquid interface, TIMP4 overexpression reduced ciliated cell numbers. …”
Get full text

Circulation and Spillover of pdmH1N1 Influenza A Virus at an Educational Swine Farm in Chile, 2019–2023 by Soledad Ruiz, Constanza Díaz-Gavidia, María Antonieta González, Pablo Galdames, Cristóbal Oyarzún, Cecilia Baumberger, Camila Rojas, Christopher Hamilton-West, Bridgett Sharp, Shaoyuan Tan, Stacey Schultz-Cherry, Pedro Jimenez-Bluhm

“…However, the close contact between humans and farm animals creates a significant interface for zoonotic disease transmission, yet research on infectious diseases in such settings remains limited. …”
Get full text

WiPy-RT: A Fast Ray Tracing Modeling Platform for RIS-Assisted Wireless Channels by Mohammadreza Farashahi, Boon-Chong Seet, Xue Jun Li

“…WiPy-RT features an interactive interface that leverages highly configurable and open-source Python libraries for 3D structures, including PyVista, Trimesh, and PyTorch3D. …”
Get full text

Primary Fixation Feature Design Does Not Influence Total Ankle Tibial Component Stability When Implanted with Press-Fit in High Density Bone by Joshua E. Johnson PhD, Gabriel A. Clarke MS, Cesar de Cesar Netto MD, PhD, Donald D. Anderson PhD

“…Implant positioning and interference fit (100 µm) were set according to surgical guidelines (Fig. 1A). …”
Get full text

Revolutionizing oncology care: pioneering AI models to foresee pneumonia-related mortality by Qunzhe Ding, Yi Zhang, Zihao Zhang, Peijie Huang, Rui Tian, Zhigang Zhou, Ruilan Wang, Yun Xie

“…Additionally, our model was validated using a cohort of cancer patients from our institution and deployed via a free-access software interface.ResultsThe most common cancers resulting in pneumonia-related deaths were prostate (n=7300) and breast (n=5107) cancers, followed by lung and bronchus (n=2839) cancers. …”
Get full text

Exploring the Relationship between Spatiotemporal Distribution of Urban Vibrancy and Neighborhood Attributes by Coupling Multi-Source Data: A Case of Nanshan District in Shenzhen by Liu Feng, Tang Zhong, Zhang Liang, Yu Lingmin, Liu Ke

“…Systematically incorporating a multidimensional set of neighborhood factors, including human vision, functionality, morphology, location, and street configuration, and utilizing spatial regression models in resonance with advanced algorithms facilitates a more profound comprehension of the spatiotemporal differentiation of urban vibrancy within urban spaces and the driving or inhibiting factors involved. …”
Get full text

Post-Trial Feedback Alters Landing Performance in Adolescent Female Athletes Using a Portable Feedback System by Thomas W Kernozek, Drew Rutherford, Becky Heinert, Jessica Onsager, Maria Lee, Jeremie Schiedermayer, Stephanie Dietrich, Renee Dade, Thomas Gus Almonroeder

“…Biomechanical methods are often complex, difficult to transport and utilize in field settings, and costly, which limits their use for injury prevention. …”
Get full text

Evaluating the User Experience and Usability of the MINI Robot for Elderly Adults with Mild Dementia and Mild Cognitive Impairment: Insights and Recommendations by Aysan Mahmoudi Asl, Jose Miguel Toribio-Guzmán, Álvaro Castro-González, María Malfaz, Miguel A. Salichs, Manuel Franco Martín

“…As these technologies continue to advance, ensuring user-friendly interfaces and seamless interactions becomes more essential. …”
Get full text

Rift propagation signals the last act of the Thwaites Eastern Ice Shelf despite low basal melt rates by Christian T. Wild, Samuel B. Kachuck, Adrian Luckman, Karen E. Alley, Meghan A. Sharp, Haylee Smith, Scott W. Tyler, Christopher Kratt, Tiago S. Dotto, Daniel Price, Keith W. Nicholls, Suzanne L. Bevan, Gabriela Collao-Barrios, Atsuhiro Muto, Martin Truffer, Ted A. Scambos, Karen J. Heywood, Erin C. Pettit, the TARSAN team

“…Meanwhile, a distributed set of phase-sensitive radar measurements indicates that the basal melting rate is generally small, likely due to a widespread robust ocean stratification beneath the ice–ocean interface that suppresses basal melt despite the presence of substantial oceanic heat at depth. …”
Get full text

High‐Resolution National‐Scale Water Modeling Is Enhanced by Multiscale Differentiable Physics‐Informed Machine Learning by Yalan Song, Tadd Bindas, Chaopeng Shen, Haoyu Ji, Wouter J. M. Knoben, Leo Lonzarich, Martyn P. Clark, Jiangtao Liu, Katie vanWerkhoven, Sam Lamont, Matthew Denno, Ming Pan, Yuan Yang, Jeremy Rapp, Mukesh Kumar, Farshid Rahmani, Cyril Thébault, Richard Adkins, James Halgren, Trupesh Patel, Arpita Patel, Kamlesh Arun Sawadekar, Kathryn Lawson

“…We also provide a CONUS‐scale hydrologic data set for further evaluation and use.…”
Get full text

Lesionia: a digital data management system to enhance collaborative management of epidemiological and clinical data of cutaneous leishmaniases patients by Emna Harigua-Souiai, Youssef Ben Salem, Maaoui Hariga, Yusr Saadi, Hejer Souguir, Hamed Chouaieb, Olufemi Adedokun, Imen Mkada, Zeineb Moussa, Akila Fathallah-Mili, Meryem Lemrani, Nabil Haddad, Ayoade Oduola, Oussama Souiai, Insaf Bel Hadj Ali, Ikram Guizani

“…It consists of a relational database, a web-based user interface (WUI) and a tool for experimental data handling and analysis of clinical and epidemiological data of CL cases. …”
Get full text

O PAPEL DA FRENTE PARLAMENTAR NA LUTA CONTRA HIV/AIDS E A TUBERCULOSE E SUA RELAÇÃO COM AS CAUSAS DO RETARDO DO DIAGNÓSTICO DA TUBERCULOSE by Camille Melo Barreto Sousa, Fabiana Barbosa Assumpção Sousa, Fátima Terezinha Scarparo Cunha, Tereza Cristina Scatena Villa, Antonio Ruffino Netto

“…Saúde e Sociedade, v.13 (3): 44-57, set-dez 2004.   PALMARES, G. Projeto de Resolução n. 272/2007. …”
Get full text

O PAPEL DA FRENTE PARLAMENTAR NA LUTA CONTRA HIV/AIDS E A TUBERCULOSE E SUA RELAÇÃO COM AS CAUSAS DO RETARDO DO DIAGNÓSTICO DA TUBERCULOSE by Camille Melo Barreto Sousa, Fabiana Barbosa Assumpção Sousa, Fátima Terezinha Scarparo Cunha, Tereza Cristina Scatena Villa, Antonio Ruffino Netto

“…Saúde e Sociedade, v.13 (3): 44-57, set-dez 2004.   PALMARES, G. Projeto de Resolução n. 272/2007. …”
Get full text

O PAPEL DA FRENTE PARLAMENTAR NA LUTA CONTRA HIV/AIDS E A TUBERCULOSE E SUA RELAÇÃO COM AS CAUSAS DO RETARDO DO DIAGNÓSTICO DA TUBERCULOSE by Camille Melo Barreto Sousa, Fabiana Barbosa Assumpção Sousa, Fátima Terezinha Scarparo Cunha, Tereza Cristina Scatena Villa, Antonio Ruffino Netto

“…Saúde e Sociedade, v.13 (3): 44-57, set-dez 2004.   PALMARES, G. Projeto de Resolução n. 272/2007. …”
Get full text

Tribological properties of polymer like carbon coatings on NBG-18 nuclear graphite under nitrogen environment by HAN Hai, LIU Huichuan, CHENG Jinjuan, CHEN Xinchun, LIU Pengxiao, QI Wei, TANG Xian

“…Then, the coefficient of friction (COF) of NBG-18 with the PLC coatings was examined in a nitrogen environment using a TRB3 friction tester at room temperature with specific testing parameters set for normal loads and sliding frequencies to identify the optimal conditions. …”
Get full text

On Numerical Characteristics of а Simplex and their Estimates by M. V. Nevskii, A. Yu. Ukhalov

“…For each load type the amount of data transmitted through the L2-L3 interface is reported for various input parameters including the number of active cores and their dependences on number of cores and operational frequency.…”
Get full text

Standardizing Survey Data Collection to Enhance Reproducibility: Development and Comparative Evaluation of the ReproSchema Ecosystem by Yibei Chen, Dorota Jarecka, Sanu Ann Abraham, Remi Gau, Evan Ng, Daniel M Low, Isaac Bevers, Alistair Johnson, Anisha Keshavan, Arno Klein, Jon Clucas, Zaliqa Rosli, Steven M Hodge, Janosch Linkersdörfer, Hauke Bartsch, Samir Das, Damien Fair, David Kennedy, Satrajit S Ghosh

“…Unlike conventional survey platforms that primarily offer graphical user interface–based survey creation, ReproSchema provides a structured, modular approach for defining and managing survey components, enabling interoperability and adaptability across diverse research settings. …”
Get full text

Numerical Simulation Study of Salt Cavern CO₂ Storage in Power-to-Gas System by Weizheng Bai, Jun Lu, Jian Wang, Xinghui Fu, Yaping Fu, Yashuai Huang, Xiao Wang, Xilin Shi

“…CO₂ leakage along the interlayer and salt rock–interlayer interfaces is a key constraint on the CO₂ tightness of subsurface salt caverns. …”
Get full text

Joining forces for pathology diagnostics with AI assistance: The EMPAIA initiative by Norman Zerbe, Lars Ole Schwen, Christian Geißler, Katja Wiesemann, Tom Bisson, Peter Boor, Rita Carvalho, Michael Franz, Christoph Jansen, Tim-Rasmus Kiehl, Björn Lindequist, Nora Charlotte Pohlan, Sarah Schmell, Klaus Strohmenger, Falk Zakrzewski, Markus Plass, Michael Takla, Tobias Küster, André Homeyer, Peter Hufnagl

“…We implemented the modular and open-source EMPAIA Platform and successfully integrated 14 AI-based image analysis apps from eight different vendors, demonstrating how different apps can use a single standardized interface. We prioritized requirements and evaluated the use of AI in real clinical settings with 14 different pathology laboratories in Europe and Asia. …”
Get full text