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    Social policy of the early 1990<sup>s</sup> in the conditions of economic reform: directions and ways of solution (Southern Ural). by N. V. Baryshnikova, O. V. Kuznetsova

    Published 2023-07-01
    “…The relevance of the problem is based on the lack of a comprehensive study of social transformations in the Southern Urals, which is the purpose of the study.   Materials and Methods. To achieve this goal, comparative-historical and problem-chronological methods were used, as well as the principles of objectivity, consistency and historicism were applied, allowing to reveal the problem in its logical factual sequence, based on documentary sources. …”
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    Taxonomic diversity in the global wheat phyllosphere mycobiome – a meta analysis by Marie Højmark Fischer, Agnieszka Rzepczynska, Agnieszka Rzepczynska, Rasmus Kjøller

    Published 2025-07-01
    “…Due to environmental concerns, it is desirable to reduce the inputs of both chemical pesticides and inorganic fertilizers. However, yield reduction must be expected when switching to low-input systems. …”
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    Radiomic Features of Mesorectal Fat as Indicators of Response in Rectal Cancer Patients Undergoing Neoadjuvant Therapy by Francesca Treballi, Ginevra Danti, Sofia Boccioli, Sebastiano Paolucci, Simone Busoni, Linda Calistri, Vittorio Miele

    Published 2025-04-01
    “…The pre-treatment MRI analysis identified significant features (out of 107) for each sequence based on the Mann–Whitney test and <i>t</i>-test. …”
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    Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients. by Ilze Elbere, Ivars Silamikelis, Ilze Izabella Dindune, Ineta Kalnina, Monta Briviba, Linda Zaharenko, Laila Silamikele, Vita Rovite, Dita Gudra, Ilze Konrade, Jelizaveta Sokolovska, Valdis Pirags, Janis Klovins

    Published 2020-01-01
    “…<h4>Background</h4>The study was conducted to investigate the effects of metformin treatment on the human gut microbiome's taxonomic and functional profile in the Latvian population, and to evaluate the correlation of these changes with therapeutic efficacy and tolerance.<h4>Methods</h4>In this longitudinal observational study, stool samples for shotgun metagenomic sequencing-based analysis were collected in two cohorts. …”
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    Optimizing fungal DNA extraction and purification for Oxford Nanopore untargeted shotgun metagenomic sequencing from simulated hemoculture specimens by Nattapong Langsiri, Wieland Meyer, Laszlo Irinyi, Navaporn Worasilchai, Nuttapon Pombubpa, Thidathip Wongsurawat, Piroon Jenjaroenpun, J. Jennifer Luangsa-ard, Ariya Chindamporn

    Published 2025-06-01
    “…However, DNA extraction for long-read sequencing-based fungal identification poses a significant challenge, as obtaining long and intact fungal DNA is imperative. …”
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    High-throughput sequencing unravels placental vascular dysfunction and oxidative stress as mechanistic drivers of advanced maternal age-associated pregnancy by Xin Sun, Yao Chen, Feifei Hu, Yumeng Qiao, He Wu, Yao Su, Yue Hu, Jie Wu, Jie Wu, Mingli Huang

    Published 2025-08-01
    “…This study employs high-throughput sequencing-based transcriptomics to investigate AMA-associated dysregulation in placental angiogenesis, exploring links to redox imbalance. …”
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    Remarkable response to crizotinib in a patient with advanced lung adenocarcinoma harboring the MPRIP-ROS1 fusion gene: A case report by Yasuyuki Kishikawa, Kohei Otsubo, Daisuke Shibahara, Yoshimasa Shiraishi, Yasuto Yoneshima, Eiji Iwama, Isamu Okamoto

    Published 2025-01-01
    “…This case also underscores the importance of comprehensive genomic profiling using hybrid capture-based next-generation sequencing to identify rare driver gene alterations that may not be detected by conventional target sequencing-based methods.…”
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