Anticancer properties of 1,2,4-triazole derivatives (literature review) by I. V. Bushuieva, M. V. Parchenko

“…Research materials primarily comprised literary sources containing information on the promising array of new biologically active compounds, particularly 1,2,4-triazole derivatives, known for their targeted anticancer properties. …”
Get full text

A global scoping review of task shifting and sharing interventions to improve the mental health of people living with HIV/AIDS by Caroline Wang Kokubun, Madelyn Smith Carlson, Benjamin George Druss, Briana Ashley Woods-Jaeger, Ameeta Shivdas Kalokhe, Jessica McDermott Sales

“…MHPSS interventions delivered by a variety of LHWs yielded promising associations on an array of mental health outcomes, including PTSD/trauma and suicidality, though understudied. …”
Get full text

Molecular Markers for Thyroid Cancer Diagnosis: Insights from MAPK Pathway Gene Expression Analysis by Breno Pupin, Ramon Varella Diniz, Maricilia Silva Costa, Maurilio Jose Chagas, André Bandiera de Oliveira Santos, Renata de Azevedo Canevari

“…<b>Methods:</b> Through a comparative analysis of malignant and benign thyroid samples, we identified 46 genes of the MAPK pathway that exhibited differential expression by PCR array analysis. <b>Results:</b> Validation through RT-qPCR and in silico analysis using TCGA confirmed significant results for CCNA1, CDKN1C, CREB1, FOS, HSPA5, JUN, MAP2K6, and SFN genes identified in our cohort, reinforcing the relevance of these biomarkers. …”
Get full text

Plasma biomarkers of amyloid, tau, astrogliosis, and axonal injury in a mixed memory clinic cohort by Helena Sophia Gleerup, Anja Hviid Simonsen, Lana Grötschel, Mathias Holsey Gramkow, Peter Høgh, Kaj Blennow, Henrik Zetterberg, Nicholas Ashton, Steen Gregers Hasselbalch

“…Plasma biomarkers show potential for future applications in primary care, treatment monitoring, and trial selection.…”
Get full text

Association of NCOA6 Gene Polymorphism with Milk Production Traits in Chinese Holstein Cows by Muhammad Talha Bin Tahir, Sahar Ghulam Mohyuddin, Yiyang Yao, Yanru Wang, Yan Liang, Niel A. Karrow, Yongjiang Mao

“…Then, the genotyping of the cows (<i>n</i> = 985) was conducted using a Sequenom MassARRAY based on previously identified SNP information. …”
Get full text

Memristor loaded cross-coupled differential voltage sense amplifier design with improved performance by Peter Bukelani Musiiwa, Shyam Akashe, Govind Murari Upadhyay, Sanjay Sharma

“…It is an active circuit capable to enhance signal promulgation from the selected cell in a memory array to peripheral logic circuits and changes the random logic levels on a bit-line to the digital logic levels of the Boolean circuits in the periphery. …”
Get full text

Multi-wavelength optical information processing with deep reinforcement learning by Qiuquan Yan, Hao Ouyang, Zilong Tao, Meili Shen, Shiyin Du, Jun Zhang, Hengzhu Liu, Hao Hao, Tian Jiang

“…In systems based on dispersion compensating fiber, micro-ring resonator array, and Mach-Zehnder interferometer array that use multi-wavelength optical carriers as the light source, the DRC method enables the completion of the corresponding signal processing functions within 21 iterations. …”
Get full text

VLA FRAMEx. II. Radio Spectra of Nearby Active Galactic Nuclei at Subarcsecond Resolution by Andrew J. Sargent, Alexander J. van der Horst, Megan C. Johnson, Travis C. Fischer, Nathan J. Secrest, Phil J. Cigan, Onic I. Shuvo, Krista L. Smith

“…Jansky Very Large Array (VLA) in its A-array configuration. Despite expectations, only 12 out of 25 of these targets have been detected by the Very Long Baseline Array (VLBA) at milliarcsecond resolution in our previous studies, and we aim to understand why the circumnuclear radio emission resolves away at the subparsec spatial scales. …”
Get full text

A Mid-Density Single-Nucleotide Polymorphism Panel for Molecular Applications in Cowpea (Vigna unguiculata (L.) Walp) by Patrick Obia Ongom, Christian Fatokun, Abou Togola, Ana Luisa Garcia-Oliveira, Eng Hwa Ng, Andrzej Kilian, Stefano Lonardi, Timothy J. Close, Ousmane Boukar

“…A core set of 2,602 targeted diversity array technology (DArTag) single-nucleotide polymorphisms (SNPs) was designed from an existing 51,128 Cowpea iSelect Consortium Array. …”
Get full text

Distributed Acoustic Sensing for aftershock monitoring: the case of the 2019 Mw 4.9 Le Teil earthquake by Martijn van den Ende, Jean-Paul Ampuero, Françoise Courboulex, Bertrand Delouis, Maxime Godano, Christophe Larroque, Anthony Sladen

“…However, locating a selected aftershock with DAS yields an accuracy and precision that is comparable to that of the seismic network, even though the DAS array has a relatively unfavourable geometry. …”
Get full text

Nexus of political tensions and cross-border contraband trade between Ethiopia and the Sudan, 1974–1991: evidences from Metema-Humera corridor and its environs by Alemayehu Erkihun Engida

“…Based on a critical examination of untapped provincial archives, contemporary periodical sources, and extensive field interviews conducted with selected local elders in the border areas, this study explores entanglements between regional diplomacy, political tensions hampered by the violence of various armed factions in the Metema-Humera border regions, the dynamics of cross-border contraband trade that involved a diverse array of actors, state failures in enforcing law in the border areas, and enduring impacts on the border regions, 1974–1991. …”
Get full text

Soil moisture sensor location-allocation using spatial association of surface moisture data by Dipankar Mandal, Raj Khosla, Louis Longchamps, Deepak Joshi

“…Balancing cost and performance is typically required when deploying a soil moisture sensor array. The sensor array's performance is essentially dependent on the appropriate placement of the sensors, which is fundamentally a location-allocation problem. …”
Get full text

Low-velocity impact damage characteristics and structural optimization of metal and CFRP through-thickness reinforcement connection structures by ZHAO Kunpeng, ZHENG Huilong, KANG Zhenya, ZHANG Saile, DONG Haibin

“…The synapse feature size and synapse array density affect internal defects in the composite material. …”
Get full text

Predictors of severe leptospirosis: a review by Madushani Wickramasinghe, Amalka Chandraratne, Dinul Doluweera, Manjula M. Weerasekera, Nilanka Perera

“…Abstract Objective Leptospirosis is a zoonosis of global importance with a wide array of clinical outcomes. The clinical course of leptospirosis varies from an undifferentiated mild febrile illness to multiorgan dysfunction and death. …”
Get full text

The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis by Lotte Alders, Elke Pirlet, Emma Gesquiere, Annelies Bronckaers

“…While insulin-like growth factor 2 (IGF-2) is identified as a key regulator of angiogenesis, the contributions of its variants remain less explored.MethodsWe compared the effects of wildtype IGF-2 with that of Des(1-6)IGF-2, which has lower affinity to IGF-binding proteins (IGFBPs), and Leu27IGF2, which interacts selectively with the IGF-Receptor 2. We analyzed their effect on endothelial cell migration and tube formation as well as on the secretome of endothelial cells using an antibody array. …”
Get full text

Integrated single-cell and bulk RNA sequencing analysis establishes a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in neuroblas... by Zhiyao Cao, Qi Wang, Yali Han, Jianwei Lin, Qi Wu, Chencheng Xu, Jingchun Lv, Lei Zhang, Hongxiang Gao, Dapeng Jiang

“…Bulk gene expression data were downloaded from GEO, The Cancer Genome Atlas (TCGA) and ArrayExpress databases and the prognostic model was constructed using univariate Cox and Least Absolute Shrinkage and Selection Operator (LASSO) analyses. …”
Get full text

Analysis of changes in the genome of the Omsk hemorrhagic fever virus (Flaviviridae: <i>Orthoflavivirus</i>) during laboratory practices for virus preservation by Zhanna S. Tyulko, Artem V. Fadeev, Aleksei G. Vasilenko, Ekaterina A. Gradoboeva, Valerii V. Yakimenko, Andrey B. Komissarov

“…Linked nucleotide substitutions were identified by calculating the mutual information for each pair of columns in the array of aligned nucleotide sequences. In the phylogenetic analysis, the relaxed clock algorithm of the BEAST program was used. …”
Get full text

QTL mapping of almond kernel quality traits in the F1 progeny of ‘Marcona’ × ‘Marinada’ by Felipe Pérez de los Cobos, Felipe Pérez de los Cobos, Felipe Pérez de los Cobos, Agustí Romero, Leontina Lipan, Xavier Miarnau, Pere Arús, Pere Arús, Iban Eduardo, Iban Eduardo, Ignasi Batlle, Alejandro Calle

“…Additionally, the 91 individuals of the population were genotyped with the almond Axiom™ 60K SNP array, and high-density linkage maps were constructed. …”
Get full text

SOME TRENDS IN THE INTERACTION BETWEEN PUBLIC AND PRIVATE LAW IN TODAY'S RUSSIA (THE ISSUES OF COMPLEX FORMATIONS IN THE SYSTEM OF LAW) by O. Kozhevnikov

“…If we need to justify the allocation of comprehensive formation (industry or institution) in law, it is important always ask yourself the logical question: do special normative means of the system organization of legal material exist in a chosen array of the laws of and what current legal instruments do give us reason to say that we have not simply a normative array, but the integrated interdisciplinary institute or branch of law. …”
Get full text

Bio-inspired flat optics for directional 3D light detection and ranging by Clément Majorel, Amir Loucif, Emil Marinov, Renato Juliano Martins, Adelin Patoux, Pierre-Marie Coulon, Virginie Brandli, Michel Antolovic, Claudio Bruschini, Edoardo Charbon, Patrice Genevet

“…Metasurfaces, or planar nanostructured optical surfaces, can overcome the limitation of curved optics, achieving panoramic vision and selective focusing of the light on a plane. On-chip vertical integration of directional metalenses on the top of a planar array of detectors enables a powerful bio-inspired LiDAR that is capable of 3D imaging over a wide field of view without using any mechanical parts. …”
Get full text