Overcoming the Silencing of Doxycycline-Inducible Promoters in hiPSC-derived Cardiomyocytes [version 1; peer review: 1 approved, 2 approved with reservations] by Michelle Guichardaz, Elisa Balmas, Alessandro Bertero, Sveva Bottini

“…Conclusions These findings underscore the need for integrating multiple strategies, including careful GSH selection, improved cassette design, epigenetic modulation, and clone screening, to develop robust dox-inducible systems that retain functionality during hiPSC differentiation.…”
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Dissecting Cowpea Genetic Variability under Moisture Stress Conditions and Implications for Drought Tolerance Breeding by Mary Singini, Michael M. Chipeta, Keston Njira, Lameck Fiwa

“…Principal component analysis based on the rank correlation matrix and the Pearson product-moment correlation coefficient revealed that most of the drought tolerant indices (MP, GMP, HM, YI, and STI) used were highly correlated with yield under stress and nonstress conditions which suggested that they are ideal for selecting drought tolerant genotypes that are stable and high yielding. From the genotypes screened under both water stress and nonstress conditions across two locations, the rank sum of indices selected 10 genotypes (MWcp66, Vuli-1, TVu-13265, MWcp27, MWcp20, MWcp59, IT99K-573-1-1, IT98K-131-2, TVu-1482, and IT 99K-529-1) as the most drought tolerant genotypes. …”
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Assessment of antenatal care quality in Ethiopia: Facility-based study using service provision assessment data. by Addisu Alehegn Alemu, Alec Welsh, Theodros Getachew, Marjan Khajehei

“…Blood pressure measurement was the most commonly performed ANC component, at 79.5%, and breast examination for cancer screening was the most neglected component of ANC, at 3.3%. …”
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Surveillance and characteristics of vancomycin-resistant Enterococcus isolates in a Chinese tertiary hospital in Shenzhen, 2018 to 2024 by Hongwei Shen, Qiaomin Zhang, Shaobo Li, Tingting Huang, Wen Ma, Daming Wang, Peng Li

“…The VRE isolates were identified and subjected to screening for the six van genes and multi-locus sequence typing (MLST) genotyping. …”
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A system of molecular markers to identify alleles of the Rht-B1 and Rht-D1 genes controlling reduced height in bread wheat by I. V. Porotnikov, O. P. Mitrofanova, O. Yu. Antonova

“…This marker system, along with the existing ones, can be used to identify dwarf ing alleles of the Rht-B1 and Rht-D1 genes in bread wheat for genetic screening of accessions from ex situ collections and/or for marker-assisted selection.…”
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Prevalence, Etiology, and Risk Factors of Mastitis in Dairy Cattle in Embu and Kajiado Counties, Kenya by Christine M. Mbindyo, George C. Gitao, Charles M. Mulei

“…A total of 395 dairy cows were initially screened for subclinical mastitis using the California mastitis test (CMT), and milk samples were aseptically collected. …”
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Glaucoma detection and staging from visual field images using machine learning techniques. by Nahida Akter, Jack Gordon, Sherry Li, Mikki Poon, Stuart Perry, John Fletcher, Thomas Chan, Andrew White, Maitreyee Roy

“…This automated DL model will assist clinicians in precision glaucoma detection and progression management during extensive glaucoma screening.…”
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Molecular Evidence of Coinfection with Acute Respiratory Viruses and High Prevalence of SARS-CoV-2 among Patients Presenting Flu-Like Illness in Bukavu City, Democratic Republic of... by Patrick Bisimwa Ntagereka, Rodrigue Ayagirwe Basengere, Tshass Chasinga Baharanyi, Théophile Mitima Kashosi, Jean-Paul Chikwanine Buhendwa, Parvine Basimane Bisimwa, Aline Byabene Kusinza, Yannick Mugumaarhahama, Dieudonne Wasso Shukuru, Simon Baenyi Patrick, Ronald Tonui, Ahadi Bwihangane Birindwa, Denis Mukwege

“…This study determined the prevalence of SARS-CoV-2 and other acute respiratory viruses among patients with flu-like symptoms in Bukavu city, Democratic Republic of Congo. We screened 1352 individuals with flu-like illnesses seeking treatment in 10 health facilities. …”
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In Vitro Antagonistic Effect of Lactic Acid Bacteria Isolated from Fermented Beverage and Finfish on Pathogenic and Foodborne Pathogenic Microorganism in Ethiopia by Fitsum Dejene, Belayneh Regasa Dadi, Dagimawie Tadesse

“…A total of 40 lactic acid bacteria were isolated; among them, 4 lactic acid bacteria, belonging to the genera Enterococcus, Leuconostoc, and Weisellia from fermented beverage and Pediococcus from fish, were screened for antimicrobial activity. The cell-free supernatant of those four isolates exhibited a significant (p<0.05) antibacterial effect against tested pathogens and foodborne pathogenic bacteria. …”
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Associations of the triglyceride-glucose index and remnant cholesterol levels with the prevalence of Carotid Plaque in patients with type 2 diabetes: a retrospective study by Xin Xu, Tianrong Pan, Xing Zhong, Yijun Du, Deyuan Zhang

“…A multivariate logistic regression study indicated that, after adjusting statistically significant variables screened in LASSO regression, TyG index [OR (95% CI): 1.810 (1.077, 3.113)] and RC [OR (95% CI): 1.988 (1.034, 3.950)] remained the risk factors for carotid plaque presence. …”
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Intestinal Parasitic Infections, Treatment and Associated Factors among Pregnant Women in Sao Tome and Principe: A Cross-Sectional Study by Alexandra Vasconcelos, Swasilanne Sousa, Nelson Bandeira, Marta Alves, Ana Luísa Papoila, Filomena Pereira, Maria Céu Machado

“…A hospital-based cross-sectional study was conducted among pregnant women admitted to the HAM who had undergone antenatal copro-parasitological screening. Data were abstracted from antenatal care (ANC) cards regarding parasitological results and anthelmintic prescriptions. …”
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Risk prediction models for stress urinary incontinence after pelvic organ prolapse (POP) surgery: a systematic review and meta-analysis by Bi Jun Yu, Hao Chong He, Li Wang, Han Mei Shao, Ying Min Liu, Xiao Ying Yan, Jian Liu

“…Methods Relevant literature in PubMed, Embase, Web of Science, Cochrane Library, OVID, China National Knowledge Infrastructure(CNKI), Wan Fang Database, VIP database and Chinese Biomedical Literature Service System (SinoMed) were search from inception to 1 March 2024. Literature screening and data extraction were performed independently by two researchers. …”
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Risk factors for early periventricular intraventricular hemorrhage in extremely low birth weight infants: a retrospective study by Yueju Cai, Yongjiang Jiang, Ping Wang, Xiaopeng Zhao, Yanyan Song, Xiaolan Li

“…Standard head ultrasound screening (HUS) was used to assess the presence and severity of IVH on days 1–3 and 5–7 post-birth. …”
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Inhibition of TFF3 synergizes with c-MET inhibitors to decrease the CSC-like phenotype and metastatic burden in ER+HER2+ mammary carcinoma by Chuyu He, Xuejuan Wang, Yi-Shiou Chiou, Basappa Basappa, Tao Zhu, Vijay Pandey, Peter E. Lobie

“…Furthermore, a high-throughput combinatorial anti-cancer compound library screening revealed that AMPC preferentially synergized with receptor tyrosine kinase c-MET inhibitors (c-METis) to reduce cell survival and the CSC-like phenotype. …”
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Tumor Necrosis Factor Receptor Superfamily, Member 1B Haplotypes Increase or Decrease the Risk of Inflammatory Bowel Diseases in a New Zealand Caucasian Population by Lynnette R. Ferguson, Dug Yeo Han, Claudia Huebner, Ivonne Petermann, Murray L. Barclay, Richard B. Gearry, Alan McCulloch, Pieter S. Demmers

“…DNA samples from 388 CD, 405 UC, 27 indeterminate colitis patients, and 293 randomly selected controls, from Canterbury, New Zealand were screened for 3 common SNPs in TNSFRSF1B: rs1061622 (c.676T>C), rs1061624 (c.∗1663A>G), and rs3397 (c.∗1690T>C), using TaqMan technologies. …”
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Clinical and novel insights into risk factors for sarcopenia in dialysis patients: a systematic review and meta-analysis by Yifei Zhang, Zeyu Zhang, Zijing Cao, Xuehui Bai, Shujiao Zhang, Shuaixing Zhang, Jingyi Tang, Junyu Xi, Yiran Xie, Yuqi Wu, Zhongjie Liu, Weijing Liu

“…Result A total of 625 articles were screened, with 610 articles excluded based on predefined eligibility criteria, resulting in 15 articles involving 2904 individuals were included in the final analysis, meta-analysis results indicate that older dialysis patients [SMD = 0.76, 95% CI (0.54, 0.99), I2 = 81%, P = 0.001], those with a lower BMI [SMD = -0.50, 95% CI (-0.80, -0.20), I2% = 87.4%, P = 0.02], a lower SMI [SMD = -2.67, 95% CI (-3.87, -1.47), I2% = 98.2%, P = 0.001], and those with diabetes [OR = 1.43, 95% CI (1.13, 1.82), I2% = 48.8%, P = 0.03] are more likely to develop sarcopenia. …”
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Streptococcus pyogenes carriage rate, associated factors and antimicrobial susceptibility profiles among urban and rural schoolchildren at Gondar city, Northwest Ethiopia by Yalewayker Gashaw, Alem Getaneh, Desie Kasew, Mitkie Tigabie, Baye Gelaw

“…All the isolates were sensitive to penicillin and cefotaxime, but 18.8% and 12.25% of the isolates were resistant to amoxicillin and tetracycline, respectively. Thus, regular screening and surveillance of Streptococcus pyogenes among schoolchildren should be conducted to minimize carriage or infections and maintain the rational use of antimicrobials. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

“…The patient underwent left open adrenalectomy after preconditioning with α- and β-blockers and histopathological examination confirmed the diagnosis of pheochromocytoma (Ki-67<5%). Screening for germline mutations did not show any genes mutation (investigated mutations: RET, TMEM127, MAX, SDHD, SDHC, SDHB, SDHAF2, SDHA, and VHL). …”
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Migration of primordial germline cells is negatively regulated by surrounding somatic cells during early embryogenesis in Drosophila melanogaster by N. V. Dorogova, A. S. Khruscheva, Iu. A. Galimova, D. Yu. Oshchepkov, D. E. Maslov, E. D. Shvedkina, K. A. Akhmetova, S. A. Fedorova

“…Further, PGC are individualized, acquire an amoeboid form, and actively move through the midgut epithelium and migrate to the 5–6 abdominal segment of the embryo, where they form paired embryonic gonads. We screened for genes expressed in the epithelium surrounding PGC during early embryogenesis and affecting their migration. …”
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Profile of Children With Non-alcoholic Fatty Liver Disease Referred to a Hospital in Iran by Amin Ghanbari, Mohammadreza Pazoki, Bahar Allahverdi, Pejman Rohani, Parisa Rahmani

“…Demographic and laboratory data were collected from an electronic health record system, and lifestyle information (physical activity (PA) and nutrition) was gathered using a standardized screening questionnaire. Statistical tests such as chi-square, Fisher’s exact, independent sample t-test, and ANOVA were performed in SPSS software, version 27. …”
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