Genome sequencing enhances the diagnostic yield and expands the genetic landscape of male breast cancer by Wen Wen, Sen Zhao, Yiwen Jiang, Chengzhu Ou, Changyuan Guo, Ziqi Jia, Jiayi Li, Yansong Huang, Hengyi Xu, Pengming Pu, Tongxuan Shang, Lin Cong, Xiang Wang, Nan Wu, Jiaqi Liu

“…Methods: Twenty-four patients with MBC underwent a multistep genetic analysis. Initial screening targeted BRCA1/2 variants followed by GS to identify pathogenic/likely pathogenic germline variants through a 3-tiered classification. …”
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Immune imbalance in the pre-ovulatory follicular microenvironment of overweight and obese women during IVF by Yang Liu, Yiran Zhao, Chengliang Zhou, Hong Zhu, Jiexue Pan, Jing Fu, Hefeng Huang, Hui Lin, Li Jin

“…Lipid profiles were screened, revealing no difference between the two groups, however, levels were higher in serum compared to FF. …”
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Association of dust exposure with anxiety and depression in the occupational population: The important role of sleep duration by Zhuoheng Shen, Yue Sun, Yang Li, Qi Zhang, Yifei Liu, Jiyan Han, Jiafei Yang, Jiangping Li, Zhiyun Ha, Yaowen Yang, Zhihong Liu, Suzhen Guan, Jian Sun

“…Methods This study was conducted from July to October 2023 at The Fifth People's Hospital of Ningxia and recruited dust-expose d occupational workers from different coal enterprises. After a series of screening 1274 valid subjects were finally included. …”
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Interventional factors influencing natural killer cell immunity in colorectal cancer: a systematic review by Wai Sinn Soh, Grace L. Burns, Tharindu Senanayake, Raquel Cameron, Kerith Duncanson, Guy D. Eslick, Sharmila S. Prasad, Stephen R. Smith, Simon Keely

“…Results The literature search identified 10,404 titles and abstracts for screening. Of these, 226 full-text papers were reviewed, and 16 studies were included for data extraction. …”
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Noninvasive Evaluation of Liver Function in Morbidly Obese Patients by Patrick H. Alizai, Isabella Lurje, Andreas Kroh, Sophia Schmitz, Tom Luedde, Julia Andruszkow, Ulf P. Neumann, Florian Ulmer

“…The LiMAx® test may be a valuable tool for noninvasive screening for NASH in obese patients.…”
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Review of communication optimization methods in federated learning by YANG Zhikai, LIU Yaping, ZHANG Shuo, SUN Zhe, YAN Dingyu

“…Federated learning, as a distributed machine learning paradigm with privacy protection capabilities, exchanges model parameters through frequent communication between clients and parameter servers, training a joint model without the raw data leaving the local area. …”
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Antiviral Activity and Underlying Mechanism of <i>Moslae herba</i> Aqueous Extract for Treating SARS-CoV-2 by Yan Feng, Qiong Ge, Jian Gao, Zhuoying Wu, Yunyi Zhang, Haiyan Mao, Beibei Wu, Changping Xu

“…Through matching 119 intersection targets of ‘disease and drug’ with 1082 differentially expressed genes of COVID-19 patients, nine genes were screened. Of the nine, the PNP and TPI1 were identified as core targets as AEMH treatment significantly regulated the mRNA expression level of the two genes on infected cells. …”
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Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur by Xue Zheng, Yuhua Luo, Rui Huo, Yiwen Wang, Youbang Chen, Mianrong Chen, Qi Zhao, Kexin Li, Hanyi Zhang, Xiaotong Li, Xiang Li, Hui Zhang, Zaopeng He, Li Huang, Chun-tao Yang

“…We utilized bioinformatics algorithms for clustering, function enrichment, feature screening and survival analysis on proteomic data from the Cancer Proteome Atlas (CPTAC) and transcriptomic data from the Cancer Genome Atlas (TCGA). …”
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Increased TSPO alleviates neuropathic pain by preventing pyroptosis via the AMPK-PGC-1α pathway by Baolong Li, Kaiming Yu, Xiongyao Zhou, Jialu Sun, Le Qi, Weiye Li, Tuo Yang, Weizhen Li, Ningning Wang, Xiaosong Gu, Shusen Cui, Rangjuan Cao

“…Furthermore, Mendelian randomization analysis of GWAS data indicated that increased TSPO expression was linked to pain relief. Through drug screening, molecular docking, and behavioral assays, we identified zopiclone as a promising TSPO-targeting drug for pain treatment. …”
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Adherence to four healthy lifestyles and their influencing factors among residents aged 35 to 75 years in Fujian province: a longitudinal study by Ze YANG, Xin FANG, Yefa ZHANG, Wenling ZHONG, Tiehui CHEN, Jingyu CHEN, Yanrong YIN, Xiaoqing LI

“…MethodsA descriptive analysis of adherence to four healthy lifestyle habits, including non-smoking, non-drinking or moderate drinking, adequate physical activity during leisure time, and a healthy diet, was conducted among 31 610 residents aged 35 – 75 years who participated in the Fujian Provincial Early Screening and Comprehensive Intervention Program for High-Risk Cardiovascular Disease from 2016 to 2022. …”
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JWST, ALMA, and Keck Spectroscopic Constraints on the UV Luminosity Functions at z ∼ 7–14: Clumpiness and Compactness of the Brightest Galaxies in the Early Universe by Yuichi Harikane, Akio K. Inoue, Richard S. Ellis, Masami Ouchi, Yurina Nakazato, Naoki Yoshida, Yoshiaki Ono, Fengwu Sun, Riku A. Sato, Giovanni Ferrami, Seiji Fujimoto, Nobunari Kashikawa, Derek J. McLeod, Pablo G. Pérez-González, Marcin Sawicki, Yuma Sugahara, Yi Xu, Satoshi Yamanaka, Adam C. Carnall, Fergus Cullen, James S. Dunlop, Eiichi Egami, Norman Grogin, Yuki Isobe, Anton M. Koekemoer, Nicolas Laporte, Chien-Hsiu Lee, Dan Magee, Hiroshi Matsuo, Yoshiki Matsuoka, Ken Mawatari, Kimihiko Nakajima, Minami Nakane, Yoichi Tamura, Hiroya Umeda, Hiroto Yanagisawa

“…Our JWST/NIRSpec observations have also revealed that very bright galaxy candidates at z ∼ 10–13 identified from ground-based telescope images before JWST are passive galaxies at z ∼ 3–4, emphasizing the necessity of strict screening and spectroscopy in the selection of the brightest galaxies at z > 10. …”
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Duration of exposure to night work and cardiovascular risk factors: results from 52,234 workers of the CONSTANCES study by Eve Bourgkard, Stéphanie Boini, Michel Grzebyk, Mathieu Dziurla, Jean Ferrières, Marcel Goldberg, Céline Ribet, Yolande Esquirol

“…BMI, blood pressure, lipids, glycaemia and SCORE2 were measured in health screening centres. Results Excess risks of moderate-high SCORE2 were observed for permanent (+ 43%), rotating (+ 72%) and former night workers (+ 101%). …”
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Evaluation of the Early Development of 6-Month-Old Babies in the Case of Maternal Postpartum Depression with or Without Bipolar Disorder by Jokthan Guivarch, Mélanie-Lou Persia, Laure Le Treut, Pauline Grandgeorge, Federico Solla, Hugo Pergeline, Michel Dugnat, Florence Askenazy, François Poinso, Arthur Varoquaux, Arnaud Fernandez

“…Conclusions: Postpartum depression was associated with a weakness in sociability and posture at the age of 6 months, without relevant developmental delay. Screening infants at an early age with specific tools allows for earlier intervention, which would positively influence their developmental trajectory.…”
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A High-Throughput Method as a Diagnostic Tool for HIV Detection in Patient-Specific Induced Pluripotent Stem Cells Generated by Different Reprogramming Methods by Daniela Hübscher, Sabine Rebs, Luis Haupt, Thomas Borchert, Celina Isabell Guessoum, Franziska Treu, Steffen Köhne, Andreas Maus, Mario Hambrecht, Samuel Sossalla, Ralf Dressel, Angela Uy, Mark Jakob, Gerd Hasenfuss, Katrin Streckfuss-Bömeke

“…Since GMP standard working procedures and screening units need virus contamination-free cell lines, we studied HIV-1 contamination in the generated iPSCs. …”
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Clinical profile and outcomes analysis of HIV infection by Ashwant Kumar, Yoganathan Chidambaram, Clement J. Dhas, Nekkanti Abilash, Murali Alagesan

“…Conclusions All adult HIV patients should be screened for side effects associated with HAART medi­cations in addition to typical HIV presentation.…”
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توزیع منطقه‌ای نیکل در خاک‌های سطحی بخش‌هایی از استان قم by زهرا موحدی راد, سمیه صدر

“…مطالعات آماری و زمین‌آماری توسط نرم‌افزارهای SPSS، Variowin و WINGSLIB انجام و نقشه‌ آلودگی با نرم‌افزار Surfer16 رسم گردید. نتایج نشان داد که غلظت عنصر در هیچ‌یک از شکل‌ها در منطقه سمیت را نشان نداد؛ اما در کاربری‌های مختلف دارای تفاوت معنی‌دار بود. …”
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A machine learning-based model for predicting paroxysmal and persistent atrial fibrillation based on EHR by Yuqi Zhang, Sijin Li, Peibiao Mai, Yanqi Yang, Niansang Luo, Chao Tong, Kuan Zeng, Kun Zhang

“…Finally, the significance of each variable was analyzed by Shapley additive explanations method. Results After screening, we found the optimal variable set consisting of 10 variables. …”
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Characterization of a chemically induced osteoarthritis model in zebrafish by Gongyi Xiao, Jin Qin, Huiping Yang, Qizhi Song, Ruobin Zhang, Junlan Huang, Yuexi Mou, Wen Liu, Xianding Sun, Mao Nie

“…Moreover, zebrafish present distinct advantages, including robust regenerative abilities, genetic editing simplicity, and efficient drug screening. Consequently, this offers a fresh avenue for investigating the pathogenesis, prevention, and potential therapeutic approaches for human OA.…”
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Impact of out-of-home nutrition labelling on people with eating disorders: a systematic review and meta-synthesis by Lucy Serpell, Dasha Nicholls, Ulrike Schmidt, Tom Jewell, Nora Trompeter, Fiona Duffy, Imogen Peebles, Emily Wadhera, Kate Chambers, Helen Sharpe, Ellen Maloney

“…Unpublished studies were searched for on Google Scholar and PsyArXiv.Eligibility criteria Studies were included if they assessed the impact of out-of-home nutrition labelling policies on individuals with eating disorders or disordered eating.Data extraction and synthesis 538 studies were screened, of which 16 studies met inclusion criteria.Results The reviewed studies included five experimental/quasi-experimental studies, five cross-sectional studies and six qualitative/mixed-methods studies. …”
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Stability and changes in meaning in life profiles and their impact on mental health among chinese university students: a latent transition analysis by Sylvia Y. C. L. Kwok, Siqi Fang, Bella Meici Huang, Alebel Addis Tesfaw, Xi Deng

“…In total, 317 students from five universities in Hong Kong participated in the survey at two time points 9 months apart.ResultsThe LTA identified three distinct profiles among the participants: meaning-oriented, bewildered, and indifferent. The LTA mover–stayer model revealed the relative stability of the students’ MIL profiles over 9 months. …”
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