Alarming rise in prevalence of obesity among children with essential hypertension: Reflection of larger global epidemiological change of adolescent nutritional status by Vishwak Gundeti, Shrikiran Aroor, Koushik H, Leslie E. Lewis, Suneel C. Mundkur, Ramesh Bhat Y, Pushpa Kini

“…Conclusion: There has been a substantial increase in the proportion of essential hypertension among children and a significant rise in the incidence of overweight/obesity among children with essential hypertension. Timely screening, lifestyle alterations, and effective care are essential for reducing long-term problems related to paediatric hypertension.…”
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Conventional magnetic resonance imaging combined with three-dimensional ultrasound for preoperative prediction of immediate ablation rate in high-intensity focused ultrasound treat... by Qiong Hao, Junwei Liu, Ruoying Hou, Wenxia Huang, Juan Liao, Zhenjiang Lin, Tijiang Zhang

“…The predicted NPVR was significantly correlated with the actual NPVR (p < 0.001).Conclusions 3D ultrasound provided essential information for screening fibroids and predicting NPVR before HIFU ablation, serving as a valuable supplement to MRI. …”
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Morpho-cultural, pathogenic, and genetic characterization of Indian isolates of Macrophomina phaseolina causing charcoal rot in soybean by Laxman Singh Rajput, Sanjeev Kumar, Kriti Pathak, Palak Acharya, Divyanshu Goswami, Vennampally Nataraj, Maranna Shivakumar, Hemant Singh Maheshwari, Saloni Mandloi, Sapna Jaiswal, Asha Yadav, Raksha Vishwakarma

“…These isolates may be useful for screening genotypes and identifying quantitative trait loci (QTL) linked to soybean charcoal rot.…”
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Development and validation of a diagnostic model for migraine without aura in inpatients by Zhu-Hong Chen, Zhu-Hong Chen, Guan Yang, Chi Zhang, Chi Zhang, Dan Su, Dan Su, Yu-Ting Li, Yu-Xuan Shang, Wei Zhang, Wen Wang

“…Our findings highlight PFO as a potential key risk factor, underscoring its importance for early prevention, screening, and diagnosis of MWoA.…”
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Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study by Manel Mateu‐Salat, Nicole Stanton‐Yonge, Frederic Sampedro Santaló, José Ignacio Vela, Jesús Díaz Cascajosa, Eva Safont Pérez, Daniela Rego‐Lorca, Ana Chico

“…Conclusion This first exploratory study in people with T1D supports the potential utility of MPR as a screening tool for subclinical neurocognitive alterations in this population.…”
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Visual and High-Efficiency Secretion of SARS-CoV-2 Nanobodies with <i>Escherichia coli</i> by Shuai Zhao, Wanting Zeng, Fang Yu, Pingping Xu, Chin-Yu Chen, Wanping Chen, Yanming Dong, Fei Wang, Lixin Ma

“…In addition, <i>E. coli</i> cells secreting the nanobodies on their surface facilitates screening and characterization of antigen-binding clones.…”
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Vitamin D associates with improved quality of life in participants with irritable bowel syndrome: outcomes from a pilot trial by Sue F Plummer, Iveta Garaiova, Elizabeth A Williams, Bernard M Corfe, Simon Tazzyman, Nicholas Richards, Andrew R Trueman, Amy L Evans, Vicky A Grant

“…IBS symptoms were not significantly improved in this pilot, although a power calculation was enabled from the intervention data.Conclusions The IBS population exhibits significant levels of vitamin D insufficiency and would benefit from screening and possible supplementation. The impact of IBS on quality of life may be reduced by vitamin D level. …”
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Classification of benign and malignant solid breast lesions on the ultrasound images based on the textural features: the importance of the perifocal lesion area by А.А. Kolchev, D.V. Pasynkov, I.A. Egoshin, I.V. Kliouchkin, О.О. Pasynkova

“…The amount of ultrasound (US) breast exams continues to grow because of the wider endorsement of breast cancer screening programs. When a solid lesion is found during the US the primary task is to decide if it requires a biopsy. …”
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Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin by Jichao Sun, Dinglan Wu, Liuhai Zheng, Huifang Wang, Jihao Zhou, Guangwei Shi, Jingbo Ma, Yuke Jiang, Zhiyu Dong, Jiexuan Li, Yuan-Qiao He, Chengchao Xu, Zhijie Li, Jigang Wang

“…Here, we explore whether immunogenic cell death (ICD) marker ERp57 translocated from endoplasmic reticulum to cell surface after drug treatment could be used as a target for CAR-NK therapy.Methods To target ERp57, a VHH phage display library was used for screening ERp57-targeted nanobodies (Nbs). A candidate Nb with high binding affinity to both human and mouse ERp57 was used for constructing CAR-NK cells. …”
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Prone Positioning and Intravenous Zanamivir may Represent Effective Alternatives for Patients with Severe ARDS Virus A (H1N1) Related Pneumonia in Hospitals with no Access to ECM... by Giuseppe Gristina, Giuseppe Nardi, Daniela Orazi, Francesco Nicola Lauria, Maria Beatrice Valli, Eleonora Lalle, Stefano Menzo, Luigi Riccioni, Maria Pia Camporiondo

“…Moreover the PCR test for A H1N1 virus was sporadically available and the emergency departments of even the largest institutions could rely only on the rapid test for the urgent screening of patients with pneumonia and respiratory failure. …”
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AI-based carbon peak prediction and energy transition optimization for thermal power industry in energy-intensive regions of China by Chenhao Huang, Zhongyang Lin, Jian Wu, Penghan Li, Chaofeng Zhang, Yanzhao Liu, Weirong Chen, Xin Xu, Jinsong Deng

“…Against this background, this study selected the East China Region, where energy consumption is permanently highest, to implement an AI-based three-step “Indicator Screening − Scenario Prediction − Policy Optimization” framework. …”
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Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach by Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav

“…The bioactive compounds present in Herb5GluCon was identified using high-resolution mass spectrometry (HRMS) and these compounds were subjected to ADME analysis using the SwissADME, pkCSM and SwissTargetPrediction servers. Results: All compounds showed strong binding energies to AA and AG. …”
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Exploring the Mechanism of Skeletal Muscle in a Tacrolimus-Induced Posttransplantation Diabetes Mellitus Model on Gene Expression Profiles by Chenlei Zheng, Cheng Wang, Tan Zhang, Ding Li, Xiao-feng Ni, Jian-Hu Lin, Linxiao Sun, Bicheng Chen

“…PPI network analysis screened eight hub genes and found that they were related to troponin and tropomyosin. …”
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Application of 2D polymerase chain reaction for single-tube detection of high-risk human papillomaviruses by Weifeng Wang, Min Jiang, Ying Liu, Xuan Wu, Yan Chen, Xiaoyun Zhang, Weiwei Liu

“…Consequently, it can be effectively utilized for early screening and prevention of cervical cancer.…”
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CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions by Lei Huang, Yalei Wen, Qin Guo, Caishi Zhang, Xiao Yang, Mei Li, YiXia Liu, Xinying Li, Jiaxin Tang, Xiaofeng Zhou, Qi Qi, Haoxing Zhang, Tongzheng Liu

“…In this study, we perform a high-throughput screening and identify Casein kinase II (CK2) as an uncharacterized upstream regulator of YAP1 turnover in cancer cells of ovarian cancer and several other cancer types. …”
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Prediction of Multiple Organ Failure Complicated by Moderately Severe or Severe Acute Pancreatitis Based on Machine Learning: A Multicenter Cohort Study by Fumin Xu, Xiao Chen, Chenwenya Li, Jing Liu, Qiu Qiu, Mi He, Jingjing Xiao, Zhihui Liu, Bingjun Ji, Dongfeng Chen, Kaijun Liu

“…Clinical and laboratory features with significant differences between patients with and without MOF were screened out by univariate analysis. Prediction models were developed for selected features through six machine learning methods. …”
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Mechanisms underlying the effects of cyanogenesis on development and reproduction of Tetranychus urticae: Insights from enzyme activity and gene expression aspects by Mufeng Wu, Xiao Liang, Ying Liu, Chunling Wu, Xingkui An, Zihua Zhao, Guifeng Hao, Ijiti Oluwole Gregory, Zhihong Li, Qing Chen

“…In addition, three CNG-enzyme combinations were screened for effective cyanogenesis and TSSM lethality. …”
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The effects of Fraxini cortex and Andrographis herba on Escherichia coli-induced diarrhea in chicken by Yunying Wang, Zhenwei Sheng, Huicong Li, Xuewen Tan, Yingqiu Liu, Weimin Zhang, Wuren Ma, Lin Ma, Yunpeng Fan

“…In this study, the model of chicken diarrhea induced by E. coli was established, and different TCM formulas were used for treatment, and finally the formula with the best effect was screened out. The research also investigated the impact of these formulas on gut microbiota and serum metabolites in chickens, using 16S rRNA sequencing technology and metabolomics. …”
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Programmes to support transitions in community care for children with complex care needs: a scoping review by Shelley Doucet, Jennifer Splane, Patricia Charlton, Alison Luke, Janet A Curran, Christine Cassidy, Sydney Breneol, Shelley McKibbon, Holly McCulloch, Jessie-Lee McIsaac, Angela Riveroll

“…After our two-stage screening process, a total of 27 articles were included for analysis. …”
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Ethanolic Extract of <i>Averrhoa carambola</i> Leaf Has an Anticancer Activity on Triple-Negative Breast Cancer Cells: An In Vitro Study by Oscar F. Beas-Guzmán, Ariana Cabrera-Licona, Gustavo A. Hernández-Fuentes, Silvia G. Ceballos-Magaña, José Guzmán-Esquivel, Luis De-León-Zaragoza, Mario Ramírez-Flores, Janet Diaz-Martinez, Idalia Garza-Veloz, Margarita L. Martínez-Fierro, Iram P. Rodríguez-Sanchez, Gabriel Ceja-Espíritu, Carmen Meza-Robles, Víctor H. Cervantes-Kardasch, Iván Delgado-Enciso

“…<b>Results</b>: Phytochemical screening revealed that the ethanolic extract was rich in flavonoids, saponins, and steroids, demonstrating an antioxidant capacity of 45%. …”
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