Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…The pharmacogenomics screening was performed from whole blood samples using the Affymetrix DMET (Drug-Metabolizing Enzymes and Transporters) Plus microarray, and confirmation of genetic variants was performed using real-time polymerase chain reaction. …”
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The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome by Tiantian Gu, Mingcai Duan, Li Chen, Yong Tian, Wenwu Xu, Tao Zeng, Lizhi Lu

“…We found that 496 differentially expressed proteins (DEPs) were screened. GO and KEGG analysis mainly enriched in glycine, serine, and threonine metabolism, tyrosine metabolism, and pyruvate metabolism. …”
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Health inequities among persons with disabilities: a global scoping review by Emre Umucu, Andrew A. Vernon, Deyu Pan, Sang Qin, Guillermina Solis, Rebecca Campa, Beatrice Lee

“…The selection criteria for articles in this study were as follows: (a) publication between 2011 and 2022, (b) written in English, (c) published in a peer-reviewed scholarly journal, and (d) a quantitative comparison of health inequities between persons with and without disabilities.ResultsA total of 363 scholarly works were initially identified, with 51 meeting the inclusion criteria after rigorous screening. In the course of our review, our team identified three overarching themes of health inequity, encompassing (a) access to healthcare and resources, (b) morbidity, mortality, & risk factors, and (c) social determinants of health. …”
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Incidence and outcomes of neonatal group B streptococcal sepsis in Qatar-a multicentre study by Sajid Salim Thyvilayil, Anvar Paraparambil Vellamgot, Khalil Salameh, Sudheer Babu Kurunthattilthazhe, Abdurahiman Elikkottil, Liliana Llerena Dominguez, Dhanya Banarjee

“…We did not observe any significant change in incidence after introducing the universal maternal screening for GBS. The overall mortality was similar to previously published data. …”
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Deficit Irrigation Response and Climate Resilience of Mediterranean Tomato Landraces by Yüksel Tüzel, Hüseyin Biyke, Omar S. Harouna, Tunç Durdu, Mahmut Tepecik, Gölgen B. Oztekin, Ulaş Tunalı, Nazim S. Gruda

“…We aimed to determine the responses of some local tomato landraces from Mediterranean countries pre-selected as drought tolerant according to previous screening tests at an early stage. Three irrigation approaches were applied: Full irrigation (Ir-Full), Deficit 1 (Ir-Def1), and Deficit 2 (Ir-Def2) irrigation. …”
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Three local plants adapt to ecological restoration of abandoned lead-zinc mines through assembly of rhizosphere bacterial communities by Wei Gao, Shuyi Chen, Xin Yu, Sumin Chen, Caijing Wan, Ying Wang, Peng Wu, Qiang Li

“…In addition, different plants have been found to have different functions in the lead-zinc ecological restoration process, including iron complex transport system-permitting proteins and ATP binding cassettes.DiscussionThis study confirms for the first time that plants adapt to the remediation process of abandoned lead-zinc mines by non-randomly assembling rhizosphere bacterial communities and functions, providing a reference for screening microbial remediation bacterial resources and plant microbe joint bioremediation strategies for lead-zinc mines.…”
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Evaluation of mental disorder related to colposcopy procedure during the COVID period: A cross-sectional study by Ilaria Bochicchio, Martina Catalano, Giovanni Deiana, Giandomenico Roviello, Pasquale Marino, Fabrizia Calenda, Alessandro R Lettini, Francesca Sanseverino

“…Background: The Coronavirus Disease (COVID-19) has had a significant impact on healthcare organizations, leading to a reduction in screening. The pandemic period has caused important psychological repercussions in the most fragile patients. …”
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Thresholds of handgrip strength for all-cause mortality in patients with chronic kidney disease: a secondary systematic review with dose-response meta-analysis by Hao Chen, Fan Zhang, Liuyan Huang, Yan Bai, Yifei Zhong, Yi Li

“…Two researchers independently screened studies, extracted data, and assessed the risk of bias. …”
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Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies by Aishwarja Dey, Subarna Rani, Rabindra Nath Acharyya, Apurba Kumar Barman, Khondoker Shahin Ahmed, Nripendra Nath Biswas, Shrabanti Dev, Asish Kumar Das

“…Method: The toxicity was screened by mortality rate, and behavioral changes in mice. …”
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Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: a systematic guideline review by Maren Bredehorst, Ana I. González-González, Lara Schürmann, Dennis Firmansyah, Christiane Muth, Jörg Haasenritter, Veronika van der Wardt, Svetlana Puzhko

“…Two reviewers independently screened the guidelines for eligibility, assessed their quality, and extracted study characteristics and relevant recommendations for further consistency analysis. …”
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Modified iris system: initial experience with a new technology for safety in hiatal surgery in pediatric patients by Joel Cazares, Eduardo De la Rosa-Bustamante, Jorge Colín-Garnica, Arturo Guillen-Cárdenas, Marbella Sepulveda-Valenzuela, Miguel Torres-Salas, Jorge Alberto Cantú-Reyes

“…Purpose: We present our initial experience with a modified IRIS U-kit system (MIUS) (Stryker, USA) for real-time esophageal visualization during Nissen fundoplication (NF) surgery in pediatric patients, aiming to enhance safety and reduce complications, especially in cases involving esophageal dysmotility and neurological impairments. …”
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The effectiveness of exercise-based interventions on muscle mass, muscle strength, functional performance, aerobic capacity, and health-related quality of life in adults with malig... by Charlotte Groenset, Magnus N. Bech, Mary Jarden, Nina Høgdal, Martin Hutchings, Charlotte Suetta, Jan Christensen

“…Two reviewers independently screened and extracted data and assessed the quality of evidence using the revised Cochrane risk-of-bias tool for randomized trials. …”
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The Combinational Effect of Enhanced Infection Control Measures and Targeted Clinical Metagenomics Surveillance on the Burden of Endemic Carbapenem and Other β-Lactam Resistance Am... by Athina Giampani, Maria Simitsopoulou, Maria Sdougka, Christos Paschaloudis, Emmanuel Roilides, Elias Iosifidis

“…<b>Methods</b>: This study had three phases: (1) the baseline phase was performed prior to intervention when first screening and sample collection were performed; (2) the intervention phase was performed when various enhanced infection control measures (EICM) were applied; and (3) the maintenance phase occurred when EICMs were combined with the implementation of targeted molecular surveillance. …”
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The influence of weather and urban environment characteristics on upper respiratory tract infections: a systematic review by Henna Hyrkäs-Palmu, Henna Hyrkäs-Palmu, Timo T. Hugg, Timo T. Hugg, Jouni J. K. Jaakkola, Jouni J. K. Jaakkola, Tiina M. Ikäheimo, Tiina M. Ikäheimo, Tiina M. Ikäheimo

“…Studies were included in the review based on predefined criteria by screening 5,789 articles and reviewing reference lists of relevant studies. …”
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The potential of Curcuma longa L. bioactive compounds as RSK inhibitors for the treatment of prostate cancer: in silico study by Olusola Olalekan Elekofehinti, Foluso Adeola Taiwo, Moses Orimoloye Akinjiyan, Ifeoluwa Rachael Adetoyi, Folasade Oluwatobiloba Ayodeji, Adedotun Olayemi Oluwatuyi, Oluwapelumi Nifesimi Akintoye, Idayat Oyinkansola Kehinde, Bolanle Esther Adedapo, Opeyemi Iwaloye

“…Forty-three (43) selected compounds from turmeric were screened against RSK. After the molecular and induced-fit docking, the hit compounds were later subjected to ADMET, MMGBSA, and QSAR analyses using the Schrödinger suite. …”
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Preventive Adolescent Health Care in Family Practice: A Program Summary by Barry Knishkowy, Moshe Schein, Alexander Kiderman, Aliza Velber, Richard Edman, John Yaphe

“…The visits included a medical evaluation, screening and counseling regarding health issues recommended by GAPS, and counseling regarding personal health concerns. …”
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Anthracyclines disaggregate and restore mutant p63 function: a potential therapeutic approach for AEC syndrome by Fabiana Boncimino, Ludovica D’Auria, Kristina Todorova, Sabina Y. van der Zanden, Jacques Neefjes, Anna Mandinova, Caterina Missero, Stefano Sol

“…By performing a high-throughput screening of epigenetic and FDA-approved compounds in a co-transfection model of wild-type and mutant p63, we found that two compounds, Doxorubicin and Epirubicin, alleviate protein aggregation and restore p63 transactivation function. …”
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Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells by Junying Lu, Keyong Fang, Shiji Wang, Lingxin Xiong, Chao Zhang, Zhongmin Liu, Xuewa Guan, Ruipeng Zheng, Guoqiang Wang, Jingtong Zheng, Fang Wang

“…Inflammatory cytokine production in culture supernatant was assessed using ELISA assay, and the possible anti-inflammatory pathway of CBT was screened using qPCR array and enrichment analysis with DAVID6.8. …”
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Hydrophobic deep eutectic solvents as novel, sustainable aids for intracellular protein release from Saccharomyces cerevisiae by Tjalling Gijsbert Tjalsma, Yannick Patrice Didion, Ziran Su, Magdalena Malankowska, Pablo Torres-Montero, José Luis Martínez, Manuel Pinelo

“…The DESs were synthesized from L-menthol, lidocaine, acetic acid, decanoic acid, oleic acid and lauric acid, and screened for viability. Next, 0.5 wt% DES was mixed in a mild alkaline buffer containing S. cerevisiae. …”
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Online illegal wildlife trade in Indonesia: strengthening the regulatory framework and law enforcement by Krismanko Padang, Nuruliawati, Zahrah Afifah, Muhammad Irfan Andriansyah, Andina Auria Dwi Putri, Nur Hafizoh, Irma Hermawati, Ade Indah Muktamarianti, Syaras Yulianti, Niken Wuri Handayani, Sofi Mardiah

“…We recommend development of screening tools for advertisements and accounts on e-commerce platforms, review of community/user guidelines to prohibit trade of protected species, and strengthening the approach of combining multi-context laws with stakeholder cooperation to prosecute online illegal wildlife trade cases.…”
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