Showing 621 - 640 results of 8,382 for search 'scryer~', query time: 4.02s Refine Results
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    A novel approach for target deconvolution from phenotype-based screening using knowledge graph by Xiaohong Wang, Meifang Zhang, Jianliang Xu, Xin Li, Jing Xiong, Haowei Cao, Fangkun Dou, Xue Zhai, Hua Sun

    Published 2025-01-01
    “…Phenotype-based screening can reveal new targets but involves a lengthy process to elucidate mechanisms and targets, hindering drug development. …”
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  9. 629

    Development and Evaluation of a Hypertension Prediction Model for Community-Based Screening of Sleep-Disordered Breathing by Feng T, Shan G, Hu Y, He H, Pei G, Zhou R, Ou Q

    Published 2025-01-01
    “…Calibration plots demonstrated excellent agreement between predictions and outcomes, while DCA confirmed significant clinical utility.Conclusion: This hypertension prediction model leverages easily accessible indicators, including oximetry data from type IV sleep monitors, enabling effective screening during community-based SDB assessments. It provides a cost-effective and practical tool for prioritizing early intervention and management strategies in both primary care and clinical settings.Keywords: sleep-disordered breathing, prediction model, hypertension, risk predictors…”
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    Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation by Aini Vuorinen, Cassandra R. Kennedy, Katherine A. McPhie, William McCarthy, Jonathan Pettinger, J. Mark Skehel, David House, Jacob T. Bush, Katrin Rittinger

    Published 2025-01-01
    “…Here we present a chemoproteomics fragment screening platform for identifying novel DUB-specific hit matter, that combines activity-based protein profiling with high-throughput chemistry direct-to-biology optimisation to enable rapid elaboration of initial fragment hits against OTU DUBs. …”
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  12. 632

    Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

    Published 2023-05-01
    “…Therefore, this study aimed to identify the optimal scFv and investigate its biological functions to further optimize the therapeutic potential of CAR-T cells targeting CEA-positive carcinoma.MethodsWe screened four reported humanized or fully human anti-CEA antibodies (M5A, hMN-14, BW431/26, and C2-45), and inserted them into a 3rd-generation CAR structure. …”
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    Antibacterial Mechanisms of Constituents from Galla chinensis Revealed by Experimental and Virtual Screening-Based Studies by Meilan Liu, Tingting Lin, Liyuan Yao, Hongfeng Chen, Yu Lu, Zhengguo Tao, Haiquan Zhao, Sheng-Xiang Qiu, Liyun Zhao

    Published 2024-01-01
    “…The following virtual screening and enzyme inhibition experiments were performed to analyse the antibacterial mechanisms of the compounds from Galla chinensis. …”
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    The Intra- and Inter-rater Reliability of an Arm Care Screening Tool in High School Baseball Coaches by Kyle A. Matsel, Stephanie N. Brown, Matt C. Hoch, Robert J. Butler, Philip M. Westgate, Terry R. Malone, Tim L. Uhl

    Published 2021-12-01
    “…# Background Preseason movement screening can identify modifiable risk factors, deterioration of function, and potential for injury in baseball players. …”
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    A Comparison of Patient Satisfaction with Emergency Department Opt-In and Opt-Out Rapid HIV Screening by Douglas A. E. White, Alicia N. Scribner, Maria E. Martin, Stacy Tsai

    Published 2012-01-01
    “…To compare patient satisfaction with emergency department (ED) opt-in and opt-out HIV screening. Methods. We conducted a survey in an urban ED that provided rapid HIV screening using opt-in (February 1, 2007–July 31, 2007) and opt-out (August 1, 2007–January 31, 2008) approaches. …”
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  20. 640

    Optimization of Spectrophotometric and Fluorometric Assays Using Alternative Substrates for the High-Throughput Screening of Lipase Activity by Jun-Young Park, Jisu Ha, Yoonseok Choi, Pahn-Shick Chang, Kyung-Min Park

    Published 2021-01-01
    “…The effects of reaction conditions on the spectrophotometric and fluorometric assays using alternative substrates (p-nitrophenyl palmitate and 4-methylumbelliferyl oleate) were investigated to optimize them for the high-throughput screening of lipase activity from agricultural products. …”
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