Effect of Jiangu Granule on miR-141 and Osteogenic Gene Dlx5/Msx2/Runx2 in Ovariectomized Mice by Zhiheng ZHANG, Wenming ZHANG, Zhenpu WEI, Chutian ZHANG, Juan YANG, Yanping LIN

“…Fat around ovary of the sham operation group was removed, but not ovary, bilateral ovaries of the saline group and Jiangu granule group were removed surgically, and administrate respectively by normal saline and Jiangu granule.After eight weeks of intervention, the tibial morphology was observed by micro-CT, the expression of microRNA-141, Dlx5, Msx2 and Runx2 in bone tissue were detected by real-time PCR, protein contents of Dlx5, Msx2 and Runx2 in bone tissue were detected by Western blot.Results:Compared with the saline group, the number, width, length, shape and distribution of trabeculae in the Jiangu granule group recovered partially, and the density and connectivity of trabeculae increased, which could not be restored to the level of the sham operation group, The area of cortical bone increased, the bone marrow cavity decreased, and basically restored to the level of the sham operation group; BMC, BMD, BV/TV, BS/TV, Tb.N increased significantly; Tb.Sp, SMI reduced significantly;the relative amount of microRNA-141 and Msx2 in bone tissue decreased significantly;the relative contents of Runx2 and Dlx5 in bone tissue increased significantly, with statistically significant differences (<italic>P</italic>&lt;0.05).Conclusion:Jiangu granule can effectively reduce the expression of miR-141, enhance the expression of key osteogenic factors such as Dlx5 and Runx2 by influencing BMP signaling pathway Dlx5/Msx2/Runx2 in bone marrow mesenchymal stem cells (BMSCs), and promote osteogenic potential, so as to prevent and treat osteoporosis.…”
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Multifaceted approach to evacuating multi-level premacular hemorrhage in a case of suspected Valsalva retinopathy – a case report by B. R. Smitha, Naman Sahni, Priyanka Gandhi, Rupal Kathare, Vishma Prabhu, Prathiba Hande, Jay Chhablani, Ramesh Venkatesh

“…The patient underwent two sessions of YAG laser membranotomy, utilizing energies of 2.5 mJ and 5 mJ, which successfully facilitated drainage of fresh hemorrhage from the sub-ILM space to the subhyaloid space and vitreous cavity. However, the presence of residual coagulated blood over the fovea resulted in persistent visual impairment, necessitating a subsequent pars plana vitrectomy (PPV). …”
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A Case of Odontogenic Infection by Streptococcus constellatus Leading to Systemic Infection in a Cogan’s Syndrome Patient by Masanobu Abe, Yoshiyuki Mori, Ryoko Inaki, Yae Ohata, Takahiro Abe, Hideto Saijo, Kazumi Ohkubo, Kazuto Hoshi, Tsuyoshi Takato

“…Odontogenic infection in immunocompromised patients tends to extend systemically beyond the oral cavity. Our case report presents a patient with sepsis due to a Streptococcus constellatus (S. constellatus) odontogenic infection in a 64-year-old-immunocompromised woman with Cogan’s syndrome. …”
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Cyclic Evolution of Synergized Spin and Orbital Angular Momenta by Lei Liu, Xiao‐Chen Sun, Yuan Tian, Xiujuan Zhang, Ming‐Hui Lu, Yan‐Feng Chen

“…Experimentally, an acoustic cavity array is designed, whose dipole resonances precisely mimic the p‐orbitals, with pressure fields featuring the spatial characteristics and velocity fields the vectorial orientations. …”
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A study comparing the effectiveness of ondansetron versus ondansetron combined with dexamethasone for preventing postoperative nausea and vomiting in laparoscopic surgeries by Rajan B. Pandya, Deepika Sathe, Ankita Joshi, Vishwas Sathe

“…Background: Postoperative nausea and vomiting (PONV) frequently occur as a side effect of general anesthesia, which can be intensified by the introduction of gas into the peritoneal cavity to create pneumoperitoneum during laparoscopic surgeries. …”
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Analysis of Falling Block Characteristics in Salt Caverns Energy Storage Space by Shengwei Dong, Taian Fang, Jifang Wan, Shan Wang, Yanqi Zhao, Xiaowen Chen, Xiaofeng Yang, Yangqing Sun

“…In addition, the hydraulic fluctuations caused by the suction and drainage of the cavity pipe column have a relatively small impact on the falling object trajectory. …”
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Evaluating Antimicrobial Effectiveness of Gold Nanoparticles against Streptococcus oralis by Batool M Al-Fahham, Rafeef Ahmed Mohamed, Juman Mohammed Taqi Al-Talqani, Ali Hadi Fahad, Julfikar Haider

“…For instance, gold nanoparticles (Au NPs) are found to be successful to control and limit the bacterial pathogenicity in the oral cavity without any cytotoxic effects on the human body. …”
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Design and Optimization Application of Cut Blasting Parameters for One-Time Completion of Blind Shaft by Yifeng Zhang, Yongsheng Jia, Nan Jiang, Quanming Xie, Lin Yuan, Yongbo Wu, Zehui Xu

“…Combined with practical engineering examples and the determination method of compensation coefficient <i>C_f</i>, three types of linear cutting patterns, namely six-hole bucket cutting, seven-hole bucket cutting, and nine-hole bucket cutting, are designed. The post-blasting cavity volume and crack length of these three different cutting methods are calculated and analyzed using numerical simulation. …”
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Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea by Joon Min Jung, Do Hyung Kim, Ye-Jee Kim, Ik Jun Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

“…Additionally, specific SPMs were more common among melanoma survivors, including nonmelanoma skin cancer, oral cavity and pharyngeal cancer, renal cancer, female breast cancer, lung cancer, pancreatic cancer, and liver cancer. …”
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All-Optical VCSEL-to-VCSEL Injection Based on Cross Gain Modulation for Routing in Multinode Flexible Spectrum Optimization in Optical Fibre Transmission Links by P. P. Dlamini, G. M. Isoe, D. Kiboi Boiyo, A. W. R. Leitch, T. B. Gibbon

“…In this paper, we experimentally present a novel, all-optical spectral efficient vertical-cavity surface-emitting laser- (VCSEL-) based technique for routing and spectrum assignment in optical networks. …”
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Selective Gene Transfer to the Retina Using Intravitreal Ultrasound Irradiation by Shozo Sonoda, Katsuro Tachibana, Toshifumi Yamashita, Makoto Shirasawa, Hiroto Terasaki, Eisuke Uchino, Ryo Suzuki, Kazuo Maruyama, Taiji Sakamoto

“…A mixture of GFP plasmid (50 μL) and bubble liposomes (BLs; 50 μL) was injected into the vitreous cavity, and US was generated to the retina using a SonoPore 4000. …”
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Body mass index in relation to dental maturation of 10 to 14 years old school children in Erbil city. A cross-sectional prospective study by Omar Fawzi Chawshli, Yara Ismael Ameen

“… Background and Objectives: Estimation of dental age is based upon the rate of development and calcification of tooth buds and their progressive sequence of eruption in the oral cavity. The tooth calcification provides a valuable indicator of dental age and serves as an index of the maturation of the child. …”
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Static Bending, Vibration, and Buckling Responses of a Sandwich Beam Composed of Five Layers Considering Honeycomb Core and CNTRC with SMA Particles and Temperature-Dependent Mater... by Mohsen Asgari, Mehdi Mohammadimehr, Mohammad Arabzadeh-Ziari, Erfan Arabzadeh-Ziari

“…In this study, the governing equations of equilibrium are obtained using the principle of minimum potential energy for deflection and buckling analyses, while Hamilton's principle is employed to obtain the governing equations of motion. Then, based on Navier's type method for simply supported boundary conditions, the deflection, critical buckling load, and the natural frequency for a sandwich beam composed of five layers are obtained. …”
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Machine learning assisted plasmonic metascreen for enhanced broadband absorption in ultra-thin silicon films by Waqas W. Ahmed, Haicheng Cao, Changqing Xu, Mohamed Farhat, Muhammad Amin, Xiaohang Li, Xiangliang Zhang, Ying Wu

“…This enhancement arises from the interaction between the resonant cavity modes and localized plasmonic modes, requiring precise tuning of plasmon resonances to match the absorption region of the silicon active layer. …”
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ULK1 methylation promotes TGF‐β1‐induced endometrial fibrosis via the FOXP1/DNMT1 axis by Yuhua Zeng, Qing Feng

“…Fibrosis and pathological changes in the uterine cavity tissues were detected by Masson and hematoxylin and eosin staining. …”
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A Study on the Effect of the Boron Potential on the Mechanical Properties of the Borided Layers Obtained by Boron Diffusion at the Surface of AISI 316L Steel by E. Hernández-Sánchez, Y. M. Domínguez-Galicia, C. Orozco-Álvarez, R. Carrera-Espinoza, H. Herrera-Hernández, J. C. Velázquez

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Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis:... by Duygu Kolay, Damla Kırıcı

“…The pain intensity was measured by the Heft-Parker visual analog scale (VAS) before injection, during access cavity preparation and access palatal canal. The data were analyzed by the chi-square and The Kruskal–Wallis tests. …”
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Adults with Treacher Collins Syndrome Share Comparable 3D Upper Airway Dimensions with Nonsyndromic Individuals by Renan Jhordan Mettelziefen dos Inocentes, Alexandre de Almeida Ribeiro, Maria Noel Marzano-Rodrigues, Marília Sayako Yatabe-Ioshida, Ivy Kiemle Trindade-Suedam

“…The variables analyzed were (1) total upper airway volume; (2) nasal cavity volume; (3) total pharyngeal volume; (4) nasopharyngeal volume; (5) oropharyngeal volume; (6) pharyngeal minimal cross-sectional area; (7) pharyngeal length; and (8) pharyngeal depth. …”
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Experimental Study on the Seismic Performance of Insulated Single-Sided Composite Shear Walls under Different Shear Spans and Axial Compression Ratios by Qiang Sun, Shoufeng Zhang, Ke Liu, Xinyi Wu, Guowei Zhang, Bei Cheng

“…The new insulated single-sided composite shear wall (NISCSW) composition involves setting a precast wall panel on one side and an insulation panel on the other side, with a middle cavity for casting concrete. To investigate the seismic performance of NISCSW under different shear spans and axial compression ratios, eight specimens are made, including six composite and two cast-in-place walls. …”
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Mathematical and Experimental Simulation of Operating Modes of Capillary Emitter of Electrostatic Colloidal Microthruster by S. V. Redko, E. B. Chubenko, V. P. Bondarenko, I. V. Nikiforov, M. S. Krakov

“…The constructed system of equations is analyzed numerically. For the system of Navier – Stokes equations, the projection method proposed by Chorin is applied. …”
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