Prevalence, incidence and modifiable factors for subtypes of mild cognitive impairment: results from the Longitudinal Ageing Study in China by Wei Chen, Yuanyuan Liu, Xulai Zhang, Juan Li, Ying Liu, ChenCheng Zhang, Shifu Xiao, Tao Wang, Yong Lu, Huali Wang, Yiru Fang, Yuping Wang, Feng Yan, Ning Su, Haining He, Yanchen Shi, Minjie Zhu, Muni Tang, Feng Bao, Yefeng Yuan, Xiaoyun Zuo, Lijuan Cui, Wenyuan Wu

“…The continued lack of understanding of the various subtypes of MCI impedes the implementation of effective measures to reduce the risk of advancing to more severe cognitive diseases.Aims To estimate the prevalence and incidence rates of two MCI subtypes—amnestic MCI (aMCI) and vascular cognitive impairment without dementia (VCIND)—and to determine modifiable factors for them among older individuals in a multiregional Chinese cohort.Method This 1-year longitudinal study surveyed a random sample of participants aged≥60 years from a large, community-dwelling cohort in China. …”
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Immunomodulatory effects of atorvastatin on peripheral blood mononuclear cells infected with Mycobacterium tuberculosis by Solima Sabeel, Solima Sabeel, Solima Sabeel, Bongani Motaung, Bongani Motaung, Mumin Ozturk, Mumin Ozturk, Trevor S. Mafu, Robert J. Wilkinson, Robert J. Wilkinson, Robert J. Wilkinson, Friedrich Thienemann, Friedrich Thienemann, Friedrich Thienemann, Reto Guler, Reto Guler, Reto Guler

“…Here, we investigated the ex vivo efficacy of atorvastatin in inducing immunomodulatory activities (phagosome maturation, autophagy, and apoptosis) and enhancing the mycobacterial killing capacity in Mycobacterium tuberculosis (Mtb)-infected peripheral blood mononuclear cells (PBMCs).MethodBlood samples from healthy donors were collected for PBMC isolation. …”
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Fourier-transform infrared spectroscopy for rapid Streptococcus pneumoniae serotyping in a tertiary care general hospital by Miriam Campos-Ruiz, Miriam Campos-Ruiz, Jun Hao Wang-Wang, Jun Hao Wang-Wang, Antoni E. Bordoy, Antoni E. Bordoy, Beatriz Rodríguez-Ponga, Beatriz Rodríguez-Ponga, Natalia Pagan, Jessica Hidalgo, María Dolores Quesada, María Dolores Quesada, María Dolores Quesada, Montserrat Giménez, Montserrat Giménez, Pere-Joan Cardona, Pere-Joan Cardona, Pere-Joan Cardona, Pere-Joan Cardona

“…Certain serotypes are more strongly associated with severe illness and antimicrobial resistance. …”
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Environmental Evidence for Overly Massive Black Holes in Low-mass Galaxies and a Black Hole–Halo Mass Relation at z ∼ 5 by Jorryt Matthee, Rohan P. Naidu, Gauri Kotiwale, Lukas J. Furtak, Ivan Kramarenko, Ruari Mackenzie, Jenny Greene, Angela Adamo, Rychard J. Bouwens, Claudia Di Cesare, Anna-Christina Eilers, Anna de Graaff, Kasper E. Heintz, Daichi Kashino, Michael V. Maseda, Sandro Tacchella, Alberto Torralba

“…We use the deep JWST/NIRcam grism survey “All the Little Things” to measure the overdensities around BL-H α emitters and around a spectroscopic reference sample of ∼300 galaxies. In our reference sample, we find that megaparsec-scale overdensity correlates with stellar mass. …”
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Analysis of Interdisciplinary Differences in the Structure of the Scientific Genre in the Introduction Section of Humanities Research Articles by Roya Peyravi, Hossein Ghorbanpoor Arani, Abbas Zaree

“…A total of 45 papers were randomly selected from indexed journals approved by the Ministry of Science over the past decade to serve as the sample. The papers were analyzed in the qualitative section of this mixed-method study using content analysis based on coding to identify the discursive moves and steps of the CARS model. …”
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What racial disparities exist in the prevalence of perinatal bipolar disorder in California? by Mercy Eigbike, Mercy Eigbike, Rebecca J. Baer, Rebecca J. Baer, Rebecca J. Baer, Nichole Nidey, Nancy Byatt, Xavier R. Ramirez, Hsiang Huang, Crystal T. Clark, Avareena Schools-Cropper, Scott P. Oltman, Scott P. Oltman, Scott P. Oltman, Laura L. Jelliffe-Pawlowski, Laura L. Jelliffe-Pawlowski, Laura L. Jelliffe-Pawlowski, Laura L. Jelliffe-Pawlowski, Kelli K. Ryckman, Karen M. Tabb, Karen M. Tabb

“…This study sought to examine racial differences in the odds of having a bipolar disorder diagnosis in perinatal women across self-reported racial groups in a large sample in California, USA.MethodThis cross-sectional study uses data from 3,831,593 women who had singleton live births in California, USA from 2011 to 2019 existing in a linked dataset which included hospital discharge records and birth certificates. …”
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PLASMOpred: A Machine Learning-Based Web Application for Predicting Antimalarial Small Molecules Targeting the Apical Membrane Antigen 1–Rhoptry Neck Protein 2 Invasion Complex by Eugene Lamptey, Jessica Oparebea, Gabriel Anyaele, Belinda Ofosu, George Hanson, Patrick O. Sakyi, Odame Agyapong, Dominic S. Y. Amuzu, Whelton A. Miller, Samuel K. Kwofie, Henrietta Esi Mensah-Brown

“…<b>Objective:</b> Falciparum malaria is a major global health concern, affecting more than half of the world’s population and causing over half a million deaths annually. …”
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Assessment and prediction of diabetic kidney disease in patients with type 2 diabetes mellitus by using an advanced biomarkers by Alyaa Hliel, Huda Ahmed, Hiba Hasan

“…Microalbuminuria has limited diagnostic role in early-stage diabetic kidney disease, because renal damage usually occurs before proteinuria. Therefore, more sensitive and specific biomarkers are needed for early detection of DKD. …”
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Assessment and prediction of diabetic kidney disease in patients with type 2 diabetes mellitus by using an advanced biomarkers by Alyaa Hliel, Huda Ahmed, Hiba Hasan

“…Microalbuminuria has limited diagnostic role in early-stage diabetic kidney disease, because renal damage usually occurs before proteinuria. Therefore, more sensitive and specific biomarkers are needed for early detection of DKD. …”
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The impact of methylome analysis on the diagnosis and treatment of CNS tumours in children and adolescents: A population-based study in Greece by Maria Filippidou, Stavros Glentis, Ilona Binenbaum, Martin Sill, Kleoniki Roka, Antonia Vlachou, Georgia Avgerinou, Jonas Ecker, Florian Selt, Martin Hasselblatt, Mirjam Blattner-Johnson, Kathrin Schramm, Clio Trougkou, Dimitrios Doganis, Nikolaos Katzilakis, Vita Ridola, Evgenia Papakonstantinou, Vassilios Papadakis, Emmanouel Hatzipantelis, Eleftheria Kokkinou, Roser Pons, Christina Kanaka-Gantenbein, Dominik Sturm, Steffen Hirsch, Nicola Dikow, Kristian W. Pajtler, Cornelis M. van Tilburg, Michael C. Frühwald, Till Milde, Olaf Witt, David T.W. Jones, Andreas Von Deimling, Felix Sahm, Kalliopi Stefanaki, Stefan M. Pfister, Antonis Kattamis

“…Additional t-distributed stochastic neighbour embedding (t-SNE) analysis allowed the possible classification of twelve tumours. Nine more samples reached high Cs using the newer brain tumour classifiers, since available. …”
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Analysis of microstructure properties of Ni-Fe MOFs and their influence on selective recognition of single and binary dye systems by Dan Xu, Xiaolin Cao, Jie Zhou, Zhihao Lin, Jing Wang, Jiatong Han, Ge Chen, Guangyang Liu, Xiaomin Xu, Yanguo Zhang, Donghui Xu

“…XRD analysis indicated that materials with higher Ni content were more prone to ligand decomposition, which is consistent with the weight loss observed in the TG-DSC between 230 and 350 °C. …”
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Harmonization of multi-center diffusion tensor tractography in neonates with congenital heart disease: Optimizing post-processing and application of ComBat by Benjamin Meyers, Vincent K. Lee, Lauren Dennis, Julia Wallace, Vanessa Schmithorst, Jodie K. Votava-Smith, Vidya Rajagopalan, Elizabeth Herrup, Tracy Baust, Nhu N. Tran, Jill V. Hunter, Daniel J. Licht, J. William Gaynor, Dean B. Andropoulos, Ashok Panigrahy, Rafael Ceschin

“…Advanced brain imaging of neonatal macrostructure and microstructure, which has prognosticating importance, is more frequently being incorporated into multi-center trials of neonatal neuroprotection. …”
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Slow virologic control but strong immune and metabolic recovery with dolutegravir-anchored therapy in an HIV cohort in Ghana by Mark Appeaning, Edwin Magomere, Alberta Mawulawoe Abotsi, Nana Ama Yeboaa Amoako, Kirk Elorm Kouffie, Becky Ewurama Tetteh, Bridget Nana Darkoa Quist, Christèle Nguepou Tchopba, Gloria Akosua Ansa, Evelyn Yayra Bonney, Peter Kojo Quashie

“…This report evaluates viral load dynamics, immune responses, and organ-level metabolic changes following antiretroviral therapy (ART) initiation. Method We collected blood samples, medical, and demographic data from ART-naïve individuals at baseline and six months post-ART, and from ART-experienced individuals at a single time point. …”
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Preparation of Magnetic Photocatalyst Fe₃O₄@SiO₂@Fe-TiO₂ and Photocatalytic Degradation Performance of Methyl Orange in Na₂SO... by Li Sun, Zilong Li, Zhigang Yuan, Ying Liu, Shunqi Mei, Fanhe Meng, Xingyu Ouyang, Yi Xiong, Ke Zhang, Zhen Chen

“…In this study, Fe₃O₄@SiO₂@TiO₂ (FS-FT (0 g)) photocatalysts, featuring a magnetic core–shell structure, and Fe-doped Fe₃O₄@SiO₂@Fe-TiO₂ (FS-FT (x g)) photocatalysts, were fabricated via the sol–gel method. Structural and compositional analyses of the processed samples were systematically conducted through X-ray diffraction (XRD), transmission electron microscopy (TEM) with selected area electron diffraction (SAED), surface-sensitive X-ray photoelectron spectroscopy (XPS), and optical property assessment via UV-Vis diffuse reflectance spectroscopy (UV-DRS). …”
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Analysis of ABCG2 gene rs2231142 single nucleotide polymorphism and risk factors in hyperuricemia by Meiting Liang, Xingxing Liu, Meng Sun, Jun Zhu, Shanshan Yang, FuRong Jing, Jingyi Shen, Yi He, Wujin Chen, Yuping Sun, Yongsheng Li

“…Individuals possessing the rs2231142 T allele demonstrate an increased probability of developing HUA, potentially more pronounced in females. The model integrating the rs2231142 T allele locus with associated clinical risk factors exhibits diagnostic efficacy for the early prediction of HUA occurrence. …”
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Efficacy of Jinshui Liujun decoction on chronic obstructive pulmonary disease patients: a systematic review and meta-analysis by Wanqiu Huang, Hui Wang, Di Wu, Lu Zhang, Jiabing Tong, Jiabing Tong, Minghui Yu, Zegeng Li, Zegeng Li, Qinjun Yang, Qinjun Yang

“…Therefore, the exact therapeutic efficacy of JLD has not been fully evaluated.ObjectivesThis study aimed to ascertain the precise therapeutic efficacy of JLD in treating COPD.Data sources and MethodA search of 10 electronic databases was conducted up to 30 November 2024. …”
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Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…Further relevant documents were identified via alerts and the stakeholder group. Review methods Realist review is a theory-orientated and explanatory approach to the synthesis of evidence. …”
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Exploring the therapeutic potential of Quercus ilex acorn extract in papillomavirus-induced lesions by Ana I. Faustino-Rocha, Maria João Pires, Maria João Neuparth, Helena Vala, Cármen Vasconcelos-Nóbrega, Irene Gouvinhas, Ana Novo Barros, Maria Inês Dias, Lillian Barros, Margarida M. S. M. Bastos, Lio Gonçalves, Luís Félix, Carlos Venâncio, Rui Medeiros, Rui Miguel Gil da Costa, Paula A. Oliveira

“…The limitation of our study was the durability of transgenic animals. As a more sensitive species, we must always be careful with the durability of the test. …”
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Latent profile analysis of fear of progression in Chinese hematologic malignancy survivors by Yating Liu, Qianqian Zhang, Jinying Zhao, Tiantian Zhang, Fei Tian, Zhixin Wang, Zhuli Shao, Xiaobin Li, Wenjun Xie, Fan Yang, Qiuyan Li, Junjie Li

“…This study aimed to identify heterogeneous profiles of FoP and their associated predictors among Chinese patients with HM. A convenience sample of patients suffering from HM were enrolled from March 2023 to February 2024. …”
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Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology by Elliot Gould, Hannah S. Fraser, Timothy H. Parker, Shinichi Nakagawa, Simon C. Griffith, Peter A. Vesk, Fiona Fidler, Daniel G. Hamilton, Robin N. Abbey-Lee, Jessica K. Abbott, Luis A. Aguirre, Carles Alcaraz, Irith Aloni, Drew Altschul, Kunal Arekar, Jeff W. Atkins, Joe Atkinson, Christopher M. Baker, Meghan Barrett, Kristian Bell, Suleiman Kehinde Bello, Iván Beltrán, Bernd J. Berauer, Michael Grant Bertram, Peter D. Billman, Charlie K. Blake, Shannon Blake, Louis Bliard, Andrea Bonisoli-Alquati, Timothée Bonnet, Camille Nina Marion Bordes, Aneesh P. H. Bose, Thomas Botterill-James, Melissa Anna Boyd, Sarah A. Boyle, Tom Bradfer-Lawrence, Jennifer Bradham, Jack A. Brand, Martin I. Brengdahl, Martin Bulla, Luc Bussière, Ettore Camerlenghi, Sara E. Campbell, Leonardo L. F. Campos, Anthony Caravaggi, Pedro Cardoso, Charles J. W. Carroll, Therese A. Catanach, Xuan Chen, Heung Ying Janet Chik, Emily Sarah Choy, Alec Philip Christie, Angela Chuang, Amanda J. Chunco, Bethany L. Clark, Andrea Contina, Garth A. Covernton, Murray P. Cox, Kimberly A. Cressman, Marco Crotti, Connor Davidson Crouch, Pietro B. D’Amelio, Alexandra Allison de Sousa, Timm Fabian Döbert, Ralph Dobler, Adam J. Dobson, Tim S. Doherty, Szymon Marian Drobniak, Alexandra Grace Duffy, Alison B. Duncan, Robert P. Dunn, Jamie Dunning, Trishna Dutta, Luke Eberhart-Hertel, Jared Alan Elmore, Mahmoud Medhat Elsherif, Holly M. English, David C. Ensminger, Ulrich Rainer Ernst, Stephen M. Ferguson, Esteban Fernandez-Juricic, Thalita Ferreira-Arruda, John Fieberg, Elizabeth A. Finch, Evan A. Fiorenza, David N. Fisher, Amélie Fontaine, Wolfgang Forstmeier, Yoan Fourcade, Graham S. Frank, Cathryn A. Freund, Eduardo Fuentes-Lillo, Sara L. Gandy, Dustin G. Gannon, Ana I. García-Cervigón, Alexis C. Garretson, Xuezhen Ge, William L. Geary, Charly Géron, Marc Gilles, Antje Girndt, Daniel Gliksman, Harrison B. Goldspiel, Dylan G. E. Gomes, Megan Kate Good, Sarah C. Goslee, J. Stephen Gosnell, Eliza M. Grames, Paolo Gratton, Nicholas M. Grebe, Skye M. Greenler, Maaike Griffioen, Daniel M. Griffith, Frances J. Griffith, Jake J. Grossman, Ali Güncan, Stef Haesen, James G. Hagan, Heather A. Hager, Jonathan Philo Harris, Natasha Dean Harrison, Sarah Syedia Hasnain, Justin Chase Havird, Andrew J. Heaton, María Laura Herrera-Chaustre, Tanner J. Howard, Bin-Yan Hsu, Fabiola Iannarilli, Esperanza C. Iranzo, Erik N. K. Iverson, Saheed Olaide Jimoh, Douglas H. Johnson, Martin Johnsson, Jesse Jorna, Tommaso Jucker, Martin Jung, Ineta Kačergytė, Oliver Kaltz, Alison Ke, Clint D. Kelly, Katharine Keogan, Friedrich Wolfgang Keppeler, Alexander K. Killion, Dongmin Kim, David P. Kochan, Peter Korsten, Shan Kothari, Jonas Kuppler, Jillian M. Kusch, Malgorzata Lagisz, Kristen Marianne Lalla, Daniel J. Larkin, Courtney L. Larson, Katherine S. Lauck, M. Elise Lauterbur, Alan Law, Don-Jean Léandri-Breton, Jonas J. Lembrechts, Kiara L’Herpiniere, Eva J. P. Lievens, Daniela Oliveira de Lima, Shane Lindsay, Martin Luquet, Ross MacLeod, Kirsty H. Macphie, Kit Magellan, Magdalena M. Mair, Lisa E. Malm, Stefano Mammola, Caitlin P. Mandeville, Michael Manhart, Laura Milena Manrique-Garzon, Elina Mäntylä, Philippe Marchand, Benjamin Michael Marshall, Charles A. Martin, Dominic Andreas Martin, Jake Mitchell Martin, April Robin Martinig, Erin S. McCallum, Mark McCauley, Sabrina M. McNew, Scott J. Meiners, Thomas Merkling, Marcus Michelangeli, Maria Moiron, Bruno Moreira, Jennifer Mortensen, Benjamin Mos, Taofeek Olatunbosun Muraina, Penelope Wrenn Murphy, Luca Nelli, Petri Niemelä, Josh Nightingale, Gustav Nilsonne, Sergio Nolazco, Sabine S. Nooten, Jessie Lanterman Novotny, Agnes Birgitta Olin, Chris L. Organ, Kate L. Ostevik, Facundo Xavier Palacio, Matthieu Paquet, Darren James Parker, David J. Pascall, Valerie J. Pasquarella, John Harold Paterson, Ana Payo-Payo, Karen Marie Pedersen, Grégoire Perez, Kayla I. Perry, Patrice Pottier, Michael J. Proulx, Raphaël Proulx, Jessica L Pruett, Veronarindra Ramananjato, Finaritra Tolotra Randimbiarison, Onja H. Razafindratsima, Diana J. Rennison, Federico Riva, Sepand Riyahi, Michael James Roast, Felipe Pereira Rocha, Dominique G. Roche, Cristian Román-Palacios, Michael S. Rosenberg, Jessica Ross, Freya E. Rowland, Deusdedith Rugemalila, Avery L. Russell, Suvi Ruuskanen, Patrick Saccone, Asaf Sadeh, Stephen M. Salazar, Kris Sales, Pablo Salmón, Alfredo Sánchez-Tójar, Leticia Pereira Santos, Francesca Santostefano, Hayden T. Schilling, Marcus Schmidt, Tim Schmoll, Adam C. Schneider, Allie E. Schrock, Julia Schroeder, Nicolas Schtickzelle, Nick L. Schultz, Drew A. Scott, Michael Peter Scroggie, Julie Teresa Shapiro, Nitika Sharma, Caroline L. Shearer, Diego Simón, Michael I. Sitvarin, Fabrício Luiz Skupien, Heather Lea Slinn, Grania Polly Smith, Jeremy A. Smith, Rahel Sollmann, Kaitlin Stack Whitney, Shannon Michael Still, Erica F. Stuber, Guy F. Sutton, Ben Swallow, Conor Claverie Taff, Elina Takola, Andrew J. Tanentzap, Rocío Tarjuelo, Richard J. Telford, Christopher J. Thawley, Hugo Thierry, Jacqueline Thomson, Svenja Tidau, Emily M. Tompkins, Claire Marie Tortorelli, Andrew Trlica, Biz R. Turnell, Lara Urban, Stijn Van de Vondel, Jessica Eva Megan van der Wal, Jens Van Eeckhoven, Francis van Oordt, K. Michelle Vanderwel, Mark C. Vanderwel, Karen J. Vanderwolf, Juliana Vélez, Diana Carolina Vergara-Florez, Brian C. Verrelli, Marcus Vinícius Vieira, Nora Villamil, Valerio Vitali, Julien Vollering, Jeffrey Walker, Xanthe J. Walker, Jonathan A. Walter, Pawel Waryszak, Ryan J. Weaver, Ronja E. M. Wedegärtner, Daniel L. Weller, Shannon Whelan, Rachel Louise White, David William Wolfson, Andrew Wood, Scott W. Yanco, Jian D. L. Yen, Casey Youngflesh, Giacomo Zilio, Cédric Zimmer, Gregory Mark Zimmerman, Rachel A. Zitomer

“…In other words, analyses with results that were far from the mean were no more or less likely to have dissimilar variable sets, use random effects in their models, or receive poor peer reviews than those analyses that found results that were close to the mean. …”
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