SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper by João Pedro Ferreira, Francisco Vasques‐Nóvoa, Francisca Saraiva, Ana C. Oliveira, Jorge Almeida, Ana Beatriz Batista, Arsénio Barbosa, Ana Filipa Ferreira, Cátia Costa, Diogo Santos‐Ferreira, Fernando Friões, Cândida Goncalves, João Tiago Guimarães, Marta Leite, Pedro Marques, Joana Mascarenhas, Maria Inês Matos, Catarina Pereira, Pedro Rodrigues, Abhinav Sharma, Gualter Silva, Inês Pereira‐Sousa, Carla Sousa, Faiez Zannad, Joana Pimenta, Ricardo Fontes‐Carvalho, Adelino Leite‐Moreira

“…Compared to other HFmr/pEF trials, SOGALDI‐PEF patients were older, were more frequently women, had a high prevalence of atrial fibrillation, and had more often a preserved ejection fraction. …”
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Liver fibrosis progression analyzed with AI predicts renal decline by Dan-Qin Sun, Jia-Qi Shen, Xiao-Fei Tong, Ya-Yun Ren, Hai-Yang Yuan, Yang-Yang Li, Xin-Lei Wang, Sui-Dan Chen, Pei-Wu Zhu, Xiao-Dong Wang, Christopher D. Byrne, Giovanni Targher, Lai Wei, Vincent W.S. Wong, Dean Tai, Arun J. Sanyal, Hong You, Ming-Hua Zheng

“…In addition, liver fibrosis changes in the central vein and pericentral regions were more strongly associated with eGFR decline than in periportal, zone 2 and portal tract regions. …”
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SPP1 is a plasma biomarker associated with the dia gnosis and prediction of prognosis in sepsis by Yu Zhou Shen, Wei Xiong, Ying Chun Hu, Wu Zhong

“…The ROC curve can be used to see that it can diagnose sepsis more accurately and improve prognostic ability prediction. …”
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Hyperspectral Imaging for Detecting Plastic Debris on Shoreline Sands to Support Recycling by Roberta Palmieri, Riccardo Gasbarrone, Giuseppe Bonifazi, Giorgia Piccinini, Silvia Serranti

“…This research highlights the potential of the NIR-HSI approach as a reliable, non-invasive method for plastic debris monitoring and polymer classification. …”
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CONTROLO POSTURAL DURANTE A DUPLA TAREFA MOTORA EM JOVENS ADULTOS COM DIFERENTES NÍVEIS DE ATIVIDADE FÍSICA by Maria António Castro, João Paulo Vilas-boas, Marina Sofia Oliveira Saraiva

“…Therefore, we suggest more studies that assess the influence of the level of physical activity on postural control.…”
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Relaxation Modeling of Unidirectional Carbon Fiber Reinforced Polymer Composites Before and After UV-C Exposure by Flavia Palmeri, Susanna Laurenzi

“…These experimental results were incorporated into finite element method models of a unidirectional CFRP representative volume element. …”
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How mental health status and attitudes toward mental health shape AI Acceptance in psychosocial care: a cross-sectional analysis by Birthe Fritz, Lena Eppelmann, Annika Edelmann, Sonja Rohrmann, Michèle Wessa

“…For ethical and practical reasons, these apps were considered independently of their AI integration, aiming to support the development of AI-driven mental health applications. Method In a German-speaking convenience sample N = 302 participants socio-demographic information, personality factors, mental health status, mental health literacy, and various aspects concerning the integration of AI into psychosocial care (PU, AI awareness, digital skills, app use in general) were assessed. …”
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Evolutionary characteristics of microstructure of coal-based graphene fromNingxia coals: Comprehensive characterized analysis by Ruiqing LI, Yuegang TANG, Peng LUO, Minmin JU, Xiaoting XU

“…The results indicate that the coal–based graphene products prepared from coal samples of different coal ranks in Ningxia are all few-layer graphene. …”
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Assessment of Prevalence and Risk Factors for Intestinal Parasitosis, Malnutrition, and Anemia among School Children in Ghindae Area, Eritrea by Yafet Kesete, Huruy Tesfahiwet, Ghimja Fessehaye, Yohana Kidane, Yafet Tekle, Asmerom Yacob, Biemnet Seltene

“…Protozoan infections (38.2%) were more prevalent than soil-transmitted helminthic infections (10.4%). …”
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Characterization of tongue coating microbiome from patients with colorectal cancer by Qubo Chen, Xiaoting Huang, Haiyan Zhang, Xuanting Jiang, Xuan Zeng, Wanhua Li, Hairong Su, Ying Chen, Fengye Lin, Man Li, Xiangyu Gu, Huihui Jin, Ruohan Wang, Dechang Diao, Wei Wang, Jin Li, Sufen Wei, Weizheng Zhang, Wofeng Liu, Zhiping Huang, Yusheng Deng, Wen Luo, Zuofeng Liu, Beiping Zhang

“…We further validated the potential of the tongue coating microbiota to predict the CRC by a random forest model.Results We found a greater species diversity in CRC samples, and the nucleoside and nucleotide biosynthesis pathway was more apparent in the CRC group. …”
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A Metallicity Catalog of Very Metal-poor Main-sequence Turn-off and Red Giant Stars from LAMOST DR10 by Xiangyu Li, Huiling Chen, Yang Huang, Huawei Zhang, Timothy C. Beers, Linxuan Zhu, Jifeng Liu

“…We further refined this calibration to improve its reliability for more distant stars. This method enables robust identification of VMP candidates with metallicities as low as [Fe/H] = −4.0 among both MSTO and red giant stars. …”
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Deep learning helps discriminate between autoimmune hepatitis and primary biliary cholangitis by Alessio Gerussi, Oliver Lester Saldanha, Giorgio Cazzaniga, Damiano Verda, Zunamys I. Carrero, Bastian Engel, Richard Taubert, Francesca Bolis, Laura Cristoferi, Federica Malinverno, Francesca Colapietro, Reha Akpinar, Luca Di Tommaso, Luigi Terracciano, Ana Lleo, Mauro Viganó, Cristina Rigamonti, Daniela Cabibi, Vincenza Calvaruso, Fabio Gibilisco, Nicoló Caldonazzi, Alessandro Valentino, Stefano Ceola, Valentina Canini, Eugenia Nofit, Marco Muselli, Julien Calderaro, Dina Tiniakos, Vincenzo L’Imperio, Fabio Pagni, Nicola Zucchini, Pietro Invernizzi, Marco Carbone, Jakob Nikolas Kather

“…Attention heatmaps showed that ALNE tends to focus more on areas with increased inflammation, associating such patterns predominantly with AIH. …”
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Anti-ultraviolet and Super-Hydrophobic Finishing of Amino-modified Nano-SiO2 Grafted Cotton Fabric by ZHANG Guangyu; CHENG Ran; WANG Dao; XIAO Yao; WANG Hailou; ZHANG Wei

“…The 3-aminopropyltriethoxysilane(APTES) is used to prepare amino-modified nano-SiO2 sol by sol-gel method, and the surface of pretreated cotton fabric with citric acid is coated with nano-SiO2 by dipping method to construct a rough surface structure, and then the hexadecyl trimethoxy silane(HDTMS) is used for low surface energy modification to obtain a super-hydrophobic cotton fabric. …”
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Fitting Geometric Shapes to Fuzzy Point Cloud Data by Vincent B. Verhoeven, Pasi Raumonen, Markku Åkerblom

“…Our proposed method fits the geometry more accurately, albeit generally with greater uncertainty, and shows promise for geometry reconstruction with laser-scanned data.…”
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Dissecting the tumor microenvironment in primary breast angiosarcoma: insights from single-cell RNA sequencing by Peikai Ding, Shengbin Pei, Yi Zhai, Zheng Qu, Yazhe Yang, Xiaolong Feng, Qiang Liu, Xiangyu Wang, Wenxiang Zhang, Zhongzhao Wang, Xiangyi Kong, Jing Wang, Yi Fang

“…Objective This study aims to characterize the cellular heterogeneity and unique TME of primary breast angiosarcoma using single-cell RNA sequencing (scRNA-seq), to identify potential therapeutic targets and improve clinical outcomes. Methods Tumor samples were obtained from a patient with bilateral primary breast angiosarcoma and two patients with invasive breast cancer. …”
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CircBIRC6 affects prostate cancer progression by regulating miR-574-5p and DNAJB1 by Bin Zhao, Jinye Yang, Fengming Ran, Yuanlong Shi, Libo Yang, Yuanpeng Duan, Zhiyu Shi, Xin Li, Jianpeng Zhang, Zhiyao Li, Jiansong Wang

“…CircRNAs have been found to have regulatory roles in various diseases, such as diabetes, Central Nervous System (CNS) neuropathy, etc. where their application in cancer is even more valuable. Therefore, this paper aims to search for differentially expressed circRNAs in PCa and find downstream targeting pathways related to autophagy.Method By detecting the expression of circRNA in the samples, hsa_circ_0119816 was finally identified as the research target. …”
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Impact of heteroresistance on treatment outcomes of people with drug-resistant TB by R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura

“…METHODS: We used targeted deep sequencing to identify mutations associated with DR-TB and heteroresistance in culture samples of 624 people with DR-TB. …”
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Experimental study of microwave thawing on the LN2 frozen coals for enhancing coalbed methane extraction by Shuang Dang, Zairong Yang, Yu Zhao, Chaolin Wang, Jing Bi

“…The microwave thawing treatments generate cracks and reduce the wave velocity of the coal samples, and higher thawing power on the frozen is in more favor of forming macro-cracks under the same input energy. …”
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Demonstration of T-Cell Monotypia Using Anti-TCRbeta1/2 (<i>TRBC1</i>/2) Immunostaining as a Rapid and Cost-Effective Alternative to PCR-Based Clonality Studies for the Diagnosis o... by Elizabeth J. Soilleux, Daniel T. Rodgers, Jinlong J. Situ, Shelley C. Evans, Venkata N. Konda, Han-Chieh Yang, Jianxiong Pang, Isabella Gilbey Smith, Pete Rajesh, Maryam Salimi, Soo Weei Ng, Julia Jones, Jodi L. Miller, Rachel Etherington, Margaret Ashton-Key, Graham Ogg

“…Results: Our TCRbeta1/TCRbeta2 antibody pair gave highly specific FFPE tissue staining. All benign samples analyzed (immunohistochemically, by BaseScope^TM, by Q-PCR, and by RNAseq data analysis) had TCRbeta1/TCRbeta2 or <i>TRBC1/TRBC2</i> ranges well within the previously published flow cytometric benign range (TCRbeta2/TCRbeta1 = 0.18:1–5.7:1), while samples of T-cell lymphoma did not. …”
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Ultra-precise quantification of mRNA targets across a broad dynamic range with nanoreactor beads. by Ivan Francisco Loncarevic, Susanne Toepfer, Stephan Hubold, Susanne Klingner, Lea Kanitz, Thomas Ellinger, Katrin Steinmetzer, Thomas Ernst, Andreas Hochhaus, Eugen Ermantraut

“…A comparison of the new method against conventional real time RT-PCR analysis (reference method) with clinical samples from patients with chronic myeloid leukemia (CML) revealed excellent concordance with Pearsons correlation coefficient of 0.983 and slope of 1.08.…”
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