Integrating local malaria molecular monitoring into regular malaria indicator surveys on Bioko Island: high association between urban communities and low-density infections by Thomas C. Stabler, Salome Hosch, Elizabeth Nyakarungu, Johanna Nouria Giger, Monserrat Kobe Elonga, Rosalia Nzang Bibang, Victoria Mangue Ndong, Ilda Elobe Mometolo, Alejandro Lopelo Bolopa, Rosa Maria Oko Bedoung, Jose Raso Bijeri, Esperanza Willy Roka, Ana Gertrudis Nguema, Victoria Palacios Ichinda, Salvador Bakale, Cristina Nka Esokolete, Matilde Riloha Rivas, David S. Galick, Wonder Philip Phiri, Carlos A. Guerra, Guillermo A. García, Luca Montemartini, Tobias Schindler, Joana C. Silva, Claudia Daubenberger

“…Methods The study utilized a combination of RDTs and the DiaxxoPCR device for molecular monitoring. …”
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Candida and Bacterial Skin Colonisation of Critically-ill Patients in Two Tertiary Healthcare Facilities in Zambia by Prof Geoffrey Kwenda, Dr John Mwaba, Ms Chalwe Sokoni, Mr Christone Kaile, Ms Faith Kabansa, Mr Darlingtone Mwenya, Ms Tshiama Mirriam Mwamba, Ms Ruth Mpembe, Dr Sabelle Jallow, Ms Rudzani Mashau, Prof Nelesh Govender, Miss Chalwe Sokoni

“…This study aimed to investigate the prevalence of Candida and bacterial colonisation in critically ill patients in Zambia. Methods: In a Point-prevalence survey (PPS) for Candida and bacterial skin colonisation conducted on October 2 and 3, 2023, skin swab samples (composite axilla/groin) were collected from critically-ill patients who were admitted for at least 48 hours to two tertiary hospitals in Zambia. …”
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Foresight-based Business Model Design: Presentation and Validation of a Conceptual Model by Salman Hosseini Safa, Safar Fazli, Hakem Ghasemi, Ali Khaleghi

“…A few of them focused on some aspects of future research, while giving more importance to sustainability and the business model design space. …”
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Mechanistic Insights into Shenzhuo Formula for Diabetic Retinopathy: Integrating UPLC-Q-TOF-MS/MS, Network Pharmacology, Single-Cell RNA Sequencing Data, and Experimental Validatio... by Zang X, Zhang L, Ma J, Wang A, Ding L, Wang Y, Sun J, Li J, Hang X, Li X, Zhao L

“…Therefore, there is an urgent need to develop safer and more effective therapeutic strategies for early-stage DR. …”
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Role of LncRNA in Trauma Susceptibility and Resilience to Post-Traumatic Stress Disorder (PTSD): A Pilot Study in the African American Population by Sadhukhan T, Rai N, Misiak-Christian M, Hipolito MMS, Sadhukhan S, Shelby M, Mejía Mondragón CI, Idowu A, Gondringer A, Kalejaiye A, Li J, Islam MN, Ressom HW, Nwulia EA

“…Further evaluation of the relationship between these differentially expressed lncRNAs and PTSD should be conducted with larger samples and more diverse cohorts.Keywords: PTSD, lncRNA, CYP1B1-AS1, SLC7A11-AS1, NFAT5…”
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Carcinogenic and non-carcinogenic hazards associated with trace elements and organochlorines from fish consumption in tropical river watershed by D. Dwiyitno, F. Ariyani, G.R. Barokah, D. Yogaswara, R. Grandiosa, E. Frimawaty, H.E. Irianto, Y. Sani

“…Additionally, organochlorine levels in fish samples were also relatively low compared to the official threshold, with concentration order of heptachlor > lindane > dichloro-diphenyl-trichloroethane > endosulfan > aldrin > endrin > dieldrin, respectively. …”
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QUALITY CONTROL EVALUATION OF LEUCODEPLETED RED BLOOD CELL COMPONENTS PREPARATION WITH TOP AND BOTTOM TECHNIQUE IN GSH BLOOD BANK IN SAO PAULO, BRAZIL by MS Aline, Akil-Fabiana, R Eduardo, AD Santos-Janaina, F Felipe, S Paula, García-Rebecca, Vianna-Thiago, Frontier-Ludwig, Moreno-Dalia

“…According to local and European standards (EDQM), these results presented more than 90% compliance, as follows: Volume: 99.98%, Hb: 99.95%, rWBC: 100%. …”
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Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease by Yuqi Qiu, Diane M. Jacobs, Karen Messer, David P. Salmon, Cheryl L. Wellington, Sophie Stukas, Carolyn Revta, James B. Brewer, Gabriel C. Léger, Brianna Askew, Lia Donahue, Stephen Kaplita, Vladimir Coric, Irfan A. Qureshi, Howard H. Feldman, The Alzheimer’s Disease Cooperative Study T2 Protect AD Study Group

“…Modeling of biomarker-informed power calculations revealed that including high NfL as a trial entry criterion could substantially reduce requisite trial sample size. Conclusions Elevated baseline plasma NfL predicted more rapid clinical decline and MRI volume loss. …”
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Correlation between interleukins in aqueous humor and vitreous humor of vitreoretinal lymphoma patients by Yurun Liu, Xinyi Zhou, Kaiyu Zhang, Shixue Liu, Ruiwen Li, Yifan Gong, Zhujian Wang, Tingting Jiang, Ting Zhang, Gezhi Xu, Junxiang Gu, Qing Chang

“…Methods This was a case series study. Reviewed were consecutive biopsy-proven B-cell VRL cases of which adequate paired AqH and VH samples were obtained for the measurement of interleukin 10 (IL-10) and interleukin 6 (IL-6). …”
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Healthcare Workers and Nonhealthcare Workers Pro-Vaccination Attitude and Its Associated Factors towards COVID-19 Vaccine Globally: A Systematic Review and Meta-Analysis by Addisu Dabi Wake

“…The aim of this systematic review and meta-analysis were to determine the global pro-vaccination attitude and associated factors towards COVID-19 vaccine among healthcare workers (HCWs) and nonhealthcare workers (non-HCWs). Methods. Different databases such as PubMed, Scopus, EMBASE, and Google Scholar were used. …”
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Increased <i>MAGE-C</i> Family Gene Expression Levels as a Biomarker of Colon Cancer Through the Demethylation Mechanism by Mikhlid H. Almutairi, Waad A. Alsoraie, Turki M. Alrubie, Ahmad S. Alkhaldi, Nada S. Alhajri, Monira A. Alaujan, Manar H. Almutairi, Bader O. Almutairi

“…The goal was to assess their potential use as cancer biomarkers for the early detection and improvement of CC treatment. Methods: <i>MAGE-C1</i>, <i>MAGE-C2</i>, and <i>MAGE-C3</i> family gene expression levels were examined using RT-PCR and qRT-PCR assays in 26 adjacent normal colon (NC) and CC tissue samples from male and female Saudi patients. …”
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CD66b⁺ Tumor-Infiltrating Neutrophil-like Monocytes as Potential Biomarkers for Clinical Decision-Making in Thyroid Cancer by Hamdullah Yanik, Ilgin Demir, Ertugrul Celik, Ece Tavukcuoglu, Ibrahim Burak Bahcecioglu, Adile Begum Bahcecioglu, Mehmet Mert Hidiroglu, Sumeyra Guler, Nese Ersoz Gulcelik, Mehmet Ali Gulcelik, Kerim Bora Yilmaz, Gunes Esendagli

“…CD66b⁺ neutrophil-like monocytes constitute a novel subset of myeloid cells that are implicated in the modulation of anti-tumor immune responses, but their role in thyroid cancer remains unclear. <i>Materials and Methods:</i> Peripheral blood and thyroid nodule tissue samples were obtained from 24 patients with papillary thyroid carcinoma, and from 10 patients who underwent surgery for symptoms of tracheal compression due to benign thyroid nodules. …”
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Changes in tree-ring wood density of European beech (Fagus sylvatica L.), silver fir (Abies alba Mill.), and Norway spruce (Picea abies (L.) H. Karst.) in European mountain forests... by Chiara Torresan, Torben Hilmers, Admir Avdagić, Edmondo Di Giuseppe, Matija Klopčič, Mathieu Lévesque, Florian Motte, Enno Uhl, Tzvetan Zlatanov, Hans Pretzsch

“…., tree-ring width, current tree diameter, and latewood to earlywood ratio) and drought events on wood density. Methods In total, 150 tree cores were sampled from mountain forests in Bulgaria, Bosnia and Herzegovina, Slovenia, Switzerland, and Germany. …”
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Effects of YouTube Health Videos on Mental Health Literacy in Adolescents and Teachers: Randomized Controlled Trial by Rebekka Schröder, Tim Hamer, Victoria Kruzewitz, Ellen Busch, Ralf Suhr, Lars König

“…ObjectiveThe study evaluates the effectiveness of a short educational YouTube Health video for promoting mental health literacy in adolescents and teachers. MethodsTwo independent samples of 352 adolescents and 502 teachers from Germany were recruited from a large panel, representative of the German population with internet access. …”
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Experiences Receiving and Delivering Virtual Health Care For Women: Qualitative Evidence Synthesis by Karen M Goldstein, Sharron Rushton, Allison A Lewinski, Abigail Shapiro, Tiera Lanford-Davey, Jessica N Coleman, Neetu Chawla, Dhara B Patel, Katherine Van Loon, Megan Shepherd-Banigan, Catherine Sims, Sarah Cantrell, Susan Alton Dailey, Jennifer M Gierisch

“…ConclusionsThe benefits of virtual care for health care access may be more acutely felt by women, especially those with preexisting challenges. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…Three research questions were addressed: Can the ''transient phenomenon'' be replicated in a postnatal sample? Can initial screening data predict transient status? …”
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Effects of Tanreqing injection against ventilator-associated pneumonia: a meta-analysis and systematic review of clinical studies by Pochen Li, Yang Wu, Danxia Ge, Ruyi Xu, Qianping Zhang, Yujiao Li, Lingyao Zhang, HsuanChieh Peng, Fangyu Yu

“…However, some of the included clinical studies had limitations such as small sample sizes, lack of sample size calculations. Therefore, future study designs should be more rigorous to enhance the reliability of findings.Systematic Review Registration:https://inplasy.com/inplasy-2025-2-0008/.…”
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THE IMPACT OF AGRICULTURAL POLICIES ON FOOD SECURITY IN SELECTED ARAB COUNTRIES WITH SPECIL REFERENCE TO IRAQ (WHEAT CROP MODEL) by Adnan Ahmed Thelaj, Ahmed H. Ali, Waleed I. Sultan

“…ABSTRACT The research aims to study and measure the impact of agricultural policies on the amount of output and food security of the wheat crop in some Arab countries (Egypt and Morocco) with special reference to Iraq and adopted a search on the hypothesis that agricultural policies effects of varying reflected on the food security of the wheat crop in the countries of the research sample , also adopted Find descriptive method with quantitative analysis using the method of least squares routine to determine the effect of some economic indicators, agricultural independent dependent variable amount of agricultural output of wheat and then measure the amount of estimated output of the first model with some indicators of the economic policies of agricultural in the size of the food gap of wheat crop using the method of least squares routine two-stage, in order to achieve more accurate results, and the most important conclusions of the research is the inability of the amount of output of wheat to keep pace with the quantities consumed due to the increase and the rapid growth in population in all countries in the research sample and this leads to increase aggregate demand for this crop and the inability to reach the stage of self-sufficiency.…”
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Histological Findings in Infective Endocarditis—A Retrospective Cohort Study Conducted at “Dr. Carol Davila” Central Military Emergency University Hospital in Bucharest by Corina-Ioana Anton, Ion Ștefan, Sorin Duțulescu, Florica Stăniceanu, Cosmin Alexandru Buzilă, Alexia-Teodora Ștefan, Adrian Streinu-Cercel

“…Consequently, pathologists and clinicians face significant difficulties in distinguishing between genuine infective processes and the normal wear and tear of mechanical valves. Method: This retrospective cohort study was conducted between January 2017 and January 2024 and examined tissue samples from 93 patients who underwent a surgical removal of mechanical heart valves, with 41 cases suspected of infective endocarditis and 52 cases of non-IE. …”
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Soil physico-chemical properties and microbial diversity on chilli anthracnose disease severity in Northern Karnataka, India by Simran Panigatti, Devarajan Thangadurai, Jeyabalan Sangeetha, Ravichandra Hospet, Govardhana Guggalada Yadav, Smita Shinde, Vijaykumar Narayanaswamy Kondenahalli, Prabhudeva Shantappa Ajjappalavara, Poojashree Nagappa Kummur, Umesh Madar, Jiaojiao Song, Kasem Soytong

“…The soil physico-chemical (texture, moisture, density, pH, EC, OC, N, P, K, Ca, Mg, S, Zn, Cu, Fe, and B) properties, microbial (fungi and bacteria) diversity of 17 soil samples were analysed by standard protocols and evaluated their correlation with % DI, using Pearson correlation and cluster analysis method. …”
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