Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians' Practices across Six Randomised Controlled Trials. by Leila Rooshenas, Daisy Elliott, Julia Wade, Marcus Jepson, Sangeetha Paramasivan, Sean Strong, Caroline Wilson, David Beard, Jane M Blazeby, Alison Birtle, Alison Halliday, Chris A Rogers, Rob Stein, Jenny L Donovan, ACST-2 study group, By-Band-Sleeve study group, Chemorad study group, CSAW study group, Optima prelim study group, POUT study group

“…However, the frequency of occurrence of equipoise issues across the RCTs suggests that the findings are likely to be reflective of clinical recruiters' practices more widely.<h4>Conclusions</h4>Communicating equipoise is a challenging process that is easily disrupted. …”
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Potential overtreatment of type 2 diabetes therapy in real clinical practice: Omsk Oblast register data by I. V. Druk, D. I. Snarskaya, O. I. Goroshchenya

“…Foreign studies indicate that a significant proportion of older adults with diabetes are potentially exposed to excessive sugar-lowering therapy.Aims: to study the frequency of excessive decrease in HbA1c in a group of patients with T2DM according to a sample from the regional diabetes register.Materials and methods: A content analysis of the regional register of diabetes mellitus was carried out as of ­December 31, 2019. …”
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Meta-analysis of integrative medicine in the treatment of irradiation cystitis (中西医结合治疗放射性膀胱炎的Meta分析) by SONG Jiangman (宋江曼), LIU Feifei (刘菲菲), LIAN Xiaojing (廉晓静)

“…More high-quality clinical studies are needed for further verification. …”
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Analysis of molecular resistance and associated risk factors in tuberculosis by Zhenzhen Wang, Tengfei Guo, Liyang Xu, Jinwei Liu, Long Li, Junrong Jin, Qing Zhang, Tao Jiang, Zhanqin Zhao, Yun Xue

“…Methods Sputum samples from 25,150 non-duplicate patients attending 10 designated TB medical institutions across Luoyang City and all county and township areas under its jurisdiction from January 2019 to December 2023 were analyzed via fluorescence real-time PCR to detect Mycobacterium tuberculosis complex (MTBC)-positive strains. …”
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SARS-CoV-2 introductions to the island of Ireland: a phylogenetic and geospatiotemporal study of infection dynamics by Alan M. Rice, Evan P. Troendle, Stephen J. Bridgett, Behnam Firoozi Nejad, Jennifer M. McKinley, The COVID-19 Genomics UK consortium, National SARS-CoV-2 Surveillance & Whole Genome Sequencing (WGS) Programme, Declan T. Bradley, Derek J. Fairley, Connor G. G. Bamford, Timofey Skvortsov, David A. Simpson

“…The geographic locations and collection dates of the samples in each introduction cluster were used to map the spread of the virus across Ireland. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…Nonetheless, the symptom burden in this population is very high, and more attention is needed to provide effective multi-modal clinical therapies to this population.…”
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Nursing Complexity and Health Literacy as Determinants of Patient Outcomes: A Prospective One-Year Multicenter Cohort Study by Antonello Cocchieri, Elena Cristofori, Mario Cesare Nurchis, Nursing and Public Health Group, Gianfranco Damiani, Manuele Cesare

“…Future research should validate these findings in broader healthcare contexts and integrate multidimensional HL assessments for a more comprehensive evaluation.…”
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Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients by Liu K, Yang L, Liu Y, Zhang Y, Zhu J, Zhang H, He Z

“…However, multicenter studies with large sample size are still needed to confirm this conclusion.Keywords: large-artery atherosclerosis stroke, systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, stroke severity, predictor…”
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A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants by Zélia Breton, Emilie Stern, Mathilde Pinault, Delphine Lhuillery, Erick Petit, Pierre Panel, Maïa Alexaline

“… BackgroundAfter experiencing symptoms for an average of 7 years before diagnosis, patients with endometriosis are usually left with more questions than answers about managing their symptoms in the absence of a cure. …”
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Biomechanical Comparison of Two Plantar Lapidus Plating Systems by Felix Werneburg MD, Maria Felsberg MD, Juliane Beschauner MD, Christin Arnold MD, Darius Arbab MD, PhD, Heike Kielstein MD, Alexander Zeh MD, Karl-Stefan Delank MD, Natalia Gutteck MD

“…In contrast, the U-shaped plates were more consistent under repeated loading, suggesting potential advantages in fatigue resistance. …”
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Immune Cells as Mediators of Lipidome Influence on Osteoporosis: Evidence from a Mediation Analysis by Jiheng Xiao, Wei Zhou, Jiatai He, Yanbin Zhu, Yingze Zhang, Liming Xiong

“…Exploring lipidomic profiles offers a more comprehensive view of lipid metabolism and may reveal novel genetic links beyond traditional lipid traits. …”
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Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation: a meta-analysis and mechanism exploration by Peng Dai, Lingyu Xu, Peng Zhang, Zheng Liang, Yunhang Chu, Ziqiao Yu, Lin Cao, Peng Sun, Xia Li

“…Subgroup analysis showed that medium and high doses (100–299 mg/kg and ≥300 mg/kg) of curcumin were more stable, but the low dose group (&lt;100 mg/kg) did not conduct in-depth analysis due to insufficient sample size of individual indicators. …”
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Niveles de actividad física en población adolescente: estudio de caso (Physical activity levels in adolescents: a case study) by Guillermo Oviedo, Josep Sánchez, Rubén Castro, Mar Calvo, Juan Carlos Sevilla, Anna Iglesias, Mirian Guerra

“…In conclusion, we believe very important to seek new strategies and methods to involve more adolescents in the practice of PA, and we believe that PA sessions at school are very important.  …”
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Relationship between stressors and job burnout: Moderating role of job well-being by Jie WU, Fengmin CHENG, Ruotong YI, Weiqian YU, Chunyan LIU, Mengyu OU

“…Compared to medical staff at general hospitals, medical staff at oncology hospitals are more prone to job burnout, yet few studies in China have focused on job burnout among employees in oncology hospitals.ObjectiveTo propose a hypothetical model in which job well-being moderates the relationship between stressors and occupational burnout, to explore how stressors influence burnout and potential moderating role of job well-being, and to provide better understanding of job burnout and motivate employees based on the double-edge sword effect of stressors.MethodsA cross-sectional survey was conducted in May 2022 at a tertiary oncology specialty hospital in Chongqing, China. …”
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Research on the Influence Mechanism of “Scenery-Relics” Landscape on Public Spatio-Temporal Behavior and Perception Preference in Industrial Wasteland: A Case Study of Shougang Ind... by Sijia QIU, Lige BAO, Jing XU, Fang WEI

“…Based on the aforesaid technique, to quantify the naturalness of sample spaces, spatial metrics are employed to measure their natural degree. …”
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Knowledge, Attitudes, and Behaviors Related to Dementia Prevention and Caregiving Among Korean Americans (the KIMCHI Project): Pre- and Posttest Evaluation Study by Van Ta Park, Bora Nam, Daren Huang, Stacy W Yun, Nicole Phan, Eun Jeong Lee, Hye-Won Shin

“…Most workshop participants expressed interest in learning more about ADRD-related health topics (186/209, 89%). …”
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Study of anatomy-diagnostic features of leaves of <i>Cynara scolymus</i> L. grown under the conditions of the Kyrgyz Republic by S. C. Chubakova, N. T. Farmanova, N. V. Bobkova, T. A. Mamatov

“…Stomata of the upper epidermis are oval, those of the lower epidermis are more rounded. Stomata are surrounded by 4–5 epidermal cells. …”
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Trends and factors associated with anemia among women of reproductive age in Mali: analysis of data from 2001 to 2018 Mali demographic and health surveys by Ebenezer Kwesi Armah-Ansah, Eugene Budu, Charity Oga-Omenka, Marina Kolosnitsyna

“…We included a total weighted sample of 18,096 women of reproductive age who had participated in the hemoglobin test. …”
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High Adherence to Mediterranean Diet and Fish Intake Are Inversely Associated with Depressive Symptoms in Older Women: Findings from the Cross-Sectional NutBrain Study by Federica Prinelli, Silvia Conti, Nithiya Jesuthasan, Elena Perdixi, Matteo Cotta Ramusino, Alfredo Costa, Sara Bernini

“…The main outcome measure was a CES-D score of 16 or more. Statistical analyses were performed using a logistic regression model controlling for potential confounders. …”
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ADORA2B promotes proliferation and migration in head and neck squamous cell carcinoma and is associated with immune infiltration by Pian Li, Ke-ling Pang, Shuang-jing Chen, Dong Yang, Ai-tao Nai, Gui-cheng He, Zhe Fang, Qiao Yang, Man-bo Cai, Jun-yan He

“…High ADORA2B expression was associated with a more immunosuppressive tumor microenvironment (TME), characterized by lower immune and stromal scores and reduced immune cell infiltration. …”
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