The use of flowmetry during coronary bypass surgery in patients with diffuse coronary bed lesion by G. G. Borshchev, R. V. Sidorov, D. S. Ulbashev

“…According to our study, to predict the normal patency of shunts in the early postoperative period, it is advisable to use targets MGF above 28 ml/min for internal thoracic artery and 65 ml/min for venous shunts, PI less than 5.0 for all types of conduits, DF above 60 % for autoarterial shunt, and more than 68 % for autovenous graft.…”
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Mechanical properties of 3D voxel-printed materials for cardiovascular tissue imitation by Joël Illi, Manuel Bergamin, Marc Ilic, Anselm W. Stark, Stefan Bracher, Martin Hofmann, Juergen Burger, Isaac Shiri, Andreas Haeberlin, Christoph Gräni, Christoph Gräni

“…These resulted in slightly flatter (more linear) stress–strain curves compared to the non-linear strain-softening behavior observed in Agilus30 Clear. …”
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Identification and validation of NEIL2 as a prognostic biomarker and potential therapeutic target in cervical cancer by Yan Li, Jiayuan Du, Lingjia Wei, Tianmeng Tan, Liyi Bao, Jinqiu Su, He Wang

“…Moreover, the differential expression of NEIL2 was associated with age and disease type, with high NEIL2 expression being more common in patients with > 50 years and adenocarcinoma patients. …”
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The burden and predictors of hospital-acquired infection in intensive care units across Sub-Sahara Africa: systematic review and metanalysis by Ousman Adal, Yeshimebet Tamir Tsehay, Birhanu Ayenew, Teshager Woldegiyorgis Abate, Gebrehiwot Berie Mekonnen, Sileshi Mulatu, Sosina Tamre Mamo, Temesgen Ayenew, Mengistu Abebe Messelu, Asnake Gashaw Belayneh

“…This study aimed to assess the burden and identify predictors of HAIs in intensive care units (ICUs) across SSA. Methods This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. …”
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Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial by Xinhui Yang, Xiuying Zhang, Chen Sun, Cuiling Zhao, Xiangshuang Kong, Mingming Zhao, Linong Ji, Yufeng Li

“…Using the sealed envelope method, participants were randomly allocated (1:1) to either the acarbose group (n = 50) or the vildagliptin group (n = 50). …”
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<i>STAT4</i> rs7574865 G/T and <i>IRF5</i> rs2004640 G/T polymorphisms as markers of predisposition to juvenile idiopathic arthritis. What can genetics give to understand its heter... by E. S. Fedorov, M. Yu. Krylov, S. O. Salugina, E. Yu. Samarkina, A. N. Latypova

“…This allele was also significantly more common in the JIA-B27 (35.0 and 20.4%, respectively; p=0.044) and JIA-uveitis (45.0 and 20.4%, respectively; p=0.021) groups compared with the control one. …”
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Candida spp. colonization: a genotype source found in blood cultures that can become widespread by Aina Mesquida, Aina Mesquida, Pablo Martín-Rabadán, Pablo Martín-Rabadán, Luis Alcalá, Luis Alcalá, Almudena Burillo, Almudena Burillo, Elena Reigadas, Elena Reigadas, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Patricia Muñoz, Jesús Guinea, Jesús Guinea, Jesús Guinea, Jesús Guinea, Pilar Escribano, Pilar Escribano, Pilar Escribano

“…ObjectiveOur previous genotyping studies suggest that some anatomical locations act as reservoirs of genotypes that may cause further candidemia, since we found identical genotypes in gastrointestinal tract or catheter tip isolates and blood cultures, in contrast, we did not find blood culture genotypes in vagina samples. We observed that some genotypes can be found in blood cultures more frequently than others, some of them being called widespread genotypes because have been found in unrelated patients admitted to different hospitals. …”
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Application of droplet digital PCR in detection of seed-transmitted pathogen Acidovorax citrulli by Yu LU, Hai-jun ZHANG, Zi-jing ZHAO, Chang-long WEN, Ping WU, Shun-hua SONG, Shuan-cang YU, Lai-xin LUO, Xiu-lan XU

“…The 26 positive samples were identified in 201 commercial seed samples through ddPCR, which was the highest positive number among all the methods. …”
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Use of Population-Based Compartmental Modeling and Retinol Isotope Dilution to Study Vitamin A Kinetics and Total Body Stores among Ghanaian Women of Reproductive Age by Michael H Green, Veronica Lopez-Teros, Joanne Balmer Green, Georg Lietz, Sika M Kumordzie, Anthony Oxley, Ahmed D Fuseini, K Winifred Nyaaba, Emily Becher, Jennie N Davis, K Ryan Wessells, Seth Adu-Afarwuah, Reina Engle-Stone, Marjorie J Haskell

“…Objectives: Objectives were to apply population-based (“super-subject”) modeling to determine retinol kinetics in nonpregnant Ghanaian women of reproductive age and to use RID to predict TBS in the group and its individuals. Methods: Women (n = 89) ingested a dose of [2H6]retinyl acetate and blood samples (3/woman) were collected from 6 h to 91 d, with all participants sampled at 14 d, about half at either 21 or 28 d, and each at one other time. …”
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Molecular and serological evidence of chikungunya virus among dengue suspected patients in Sri Lanka by Mya Myat Ngwe Tun, Maurine Mumo Mutua, Shingo Inoue, Yuki Takamatsu, Satoshi Kaneko, Takeshi Urano, Rohitha Muthugala, Lakkumar Fernando, Menaka Hapugoda, YINS Gunawardene, Kouichi Morita

“…To address the gap in surveillance, this study aimed to determine the prevalence of CHIKV among patients suspected of dengue fever during the 2017–2019 DENV outbreak in Sri Lanka. Methods: Serum samples were collected from 295 patients at Kandy National Hospital and 300 patients at Negombo Hospitals, presenting with dengue-like symptoms such as fever, rash, and arthralgia. …”
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Proportion of COVID-19 survivors in 2020-2022 in the Russian population (according to the ESSE-RF3 study) by G. A. Muromtseva, S. A. Shalnova, V. A. Kutsenko, E. M. Filichkina, Yu. A. Balanova, S. E. Evstifeeva, A. E. Imaeva, A. V. Kapustina, N. S. Karamnova, M. B. Kotova, S. A. Maksimov, O. B. Shvabskaya, O. E. Ivlev, A. A. Zelenina, L. I. Gomanova, E. B. Yarovaya, A. V. Kontsevaya, T. V. Repkina, T. O. Gonoshilova, A. V. Kudryavtsev, N. I. Belova, L. L. Shagrov, M. A. Samotrueva, A. L. Yasenyavskaya, Z. N. Chernysheva, S. V. Glukhovskaya, I. A. Levina, E. A. Shirshova, E. B. Dorzhieva, E. Z. Urbanova, N. Yu. Borovkova, V. K. Kurashin, A. S. Tokareva, Yu. I. Ragino, G. I. Simonova, A. D. Khudyakova, V. N. Nikulin, O. R. Aslyamov, G. V. Khokhlova, A. V. Solovyova, A. A. Rodionov, O. V. Kryachkova, Yu. Yu. Shamurova, i. V. Tantsyreva, I. N. Baryshnikova, M. G. Ataev, M. O. Radzhabov, M. M. Isakhanova, M. A. Umetov, L. V. Elgarova, I. A. Khakuasheva, E. I. Yamashkina, M. V. Esina, T. A. Kunyaeva, A. M. Nikitina, N. V. Savvina, Yu. E. Spiridonova, E. A. Naumova, A. A. Keskinov, V. S. Yudin, S. M. Yudin, D. A. Kashtanova, M. S. Gusakova, O. M. Drapkina

“…To study the proportion of coronavirus disease 2019 (COVID-19) survivors and hospitalization cases of the Russian population for the period 2020-2022, depending on socio-demographic characteristics.Material and methods. The work was performed on random samples of the population aged 35-74 years from 15 regions participating in the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation-3 (ESSE-RF3) study. …”
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Rapid DNA and RNA isolation from few or single cells using low-cost NAxtra magnetic nanoparticles by Eirin Johannessen Starheim, Adeel Manaf, Adnan Hashim, Niklas Nonboe Andersen, Erlend Ravlo, Wei Wang, Vidar Langseth Saasen, Nina-Beate Liabakk, Sten Even Erlandsen, Per Arne Aas, Lars Hagen, Magnar Bjørås

“…Automated processing using KingFisher systems enables the rapid handling of 96 samples within 12–18 min. Our findings indicate that this method not only matches but can exceed the performance of existing alternatives in (RT)-qPCR detection while being significantly more economical and efficient. …”
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Series 2: Development of a Multiplex Amplicon Next Generation Sequencing Assay for Rapid Assessment of Resistance-Associated Mutations in <i>M. tuberculosis</i> Clinical Cases by Adriana Cabrera, Tracy Lee, Kathleen Kolehmainen, Trevor Hird, Danielle Jorgensen, Calvin Ka-Fung Lo, Hasan Hamze, Alan O’Dwyer, Dan Fornika, Rupinder Kaur KhunKhun, Mabel Rodrigues, Natalie Prystajecky, John Tyson, James E. A. Zlosnik, Inna Sekirov

“…This assay is now in use in our laboratory and offers significantly faster turnaround than both WGS and phenotypic methods on cultured isolates, enabling more rapid, informed treatment decisions for tuberculosis patients.…”
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Loss of OBSCN expression promotes bladder cancer progression but enhances the efficacy of PD-L1 inhibitors by Tao Wang, Tuanjie Guo, Juanjuan Sun, Xinyue Zang, Lei Dong, Jian Zhang, Siteng Chen, Guihua Chen, Sicong Ma, Xinyu Zhai, Chuanmin Chu, Chaofu Wang, Xiang Wang, Dongliang Xu, Mingyue Tan

“…IHC and Western blot assay identified that BLCA samples with low OBSCN expression had more CD8+ T-cell infiltration and higher PD-L1 expression. …”
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Circulation of <i>Mycobacterium tuberculosis</i> strains of the Beijing Central Asian Outbreak genotype in the Kemerovo region — Kuzbass in 2018–2022 by Svetlana N. Zhdanova, Anna A. Vyazovaya, Irina B. Lebedeva, Vyacheslav V. Sinkov, Ilya G. Kondratov, Yakov Sh. Schwartz, Lyubov V. Rychkova, Elena B. Brusina, Igor V. Mokrousov, Oleg B. Ogarkov

“…The proportion of Beijing CAO was 12.6% of the total sample; this subtype was significantly more often detected among HIV/TB (20.6%) than in HIV-negative TB patients (9.1%; p = 0.005). …”
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Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

“…The translation product of ORF1 (ORF1p) has been robustly detected by immunoassays and shotgun mass spectrometry (MS). Yet, more sensitive detection methods would enhance the use of ORF1p as a clinical biomarker. …”
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Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Furthermore, the MYC inhibitor demonstrated more sensitivity for the major nodules than minor nodules. …”
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Relationship between DLK-1 levels in blood serum and survival of patients with glioblastoma by A. I. Ryabova, V. A. Novikov, L. V. Spirina, A. B. Dospan, E. L. Choynzonov, O. V. Gribova, O. A. Muzenik, V. A. Syrkashev, S. A. Glushchenko, S. A. Tabakaev, I. N. Udintseva

“…Several studies have shown that the increased expression of delta–like noncanonical Notch ligand 1 (DLK-1) is associated with more aggressive tumor characteristics in patients with glioblastoma. …”
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A comprehensive assessment of health indicators among tribal populations in Odisha, India (Odisha Tribal Family Health Survey): a community-based, cross-sectional studyResearch in... by Jaya Singh Kshatri, Kavitha AK, Tanveer Rehman, Haimanti Bhattacharya, Dinesh Bhuyan, Asit Mansingh, Uttam Kumar Sahoo, Moushumi Nayak, Swagatika Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

“…Gaps persisted in antenatal care (40.3% completed four or more visits) and hygienic menstrual practices (35.8% of women). …”
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Association of anthropometric indices with rs9939609 FTO gene polymorphism among overweight/obese women with breast cancer: a case-control study by Huma Naqeeb, Bismillah Sehar, Sami Siraj, Ali Madi Almajwal, Bibi Hajira, MoezAlIslam Faris, Sharifa AlBlooshi, Ali Saad R. Alsubaie, Mahpara Safdar, Iftikhar Alam, Falak Zeb

“…This study aimed to assess the interactions between single nucleotide polymorphism (SNP) rs9939609 of the FTO gene, anthropometric indices, and BC risk among pre- and post-menopause women with overweight/obesity in Pakistan.MethodsThis retrospective case–control study conducted on a convenience sample of 200 women divided into two groups: a case group comprised of 100 women diagnosed with BC, and control group comprised of 100 (age and menopausal status matched healthy women). …”
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