Sensitive liquid biopsy monitoring correlates with outcome in the prospective international GPOH-DCOG high-risk neuroblastoma RT-qPCR validation study by Lieke M. J. van Zogchel, Boris Decarolis, Esther M. van Wezel, Lily Zappeij‐Kannegieter, Nina U. Gelineau, Roswitha Schumacher‐Kuckelkorn, Thorsten Simon, Frank Berthold, Max M. van Noesel, Marta Fiocco, C. Ellen van der Schoot, Barbara Hero, Janine Stutterheim, Godelieve A. M. Tytgat

“…Methods To validate sensitive neuroblastoma mRNA RT-qPCR BM testing, we prospectively assessed serial BM samples from 345 international high‐risk neuroblastoma patients, treated in trials NB2004 (GPOH) or NBL2009 (DCOG), using PHOX2B, TH, DDC, CHRNA3, and GAP43 RT-qPCR mRNA markers and BM GD2-immunocytology. …”
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Effects of salt substitute on urinary electrolytes and blood pressure in a real-world setting—cohort study in Hunan, China by Hao Wu, Wenbin Ouyang, Jing Deng, Yongmei He, Lu Yin, Xia Cao, Zhiheng Chen, Pingting Yang, Yaqin Wang, Ying Li, Xin Huang

“…No significant blood pressure differences occurred between the SS and SR groups (p > 0.05), whereas 25% KCl exposure was related to a lower level of SBP, regardless of whether it was compared with SR or 13% KCl.ConclusionCompared with salt restriction, salt substitute results in more sodium reduction and greater potassium increase. …”
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The association between uterine adenomyosis and adverse obstetric outcomes: A propensity score‐matched analysis by Rachel S. Mandelbaum, Samuel J. F. Melville, Caroline J. Violette, Joie Z. Guner, Kaitlin A. Doody, Shinya Matsuzaki, Molly M. Quinn, Joseph G. Ouzounian, Richard J. Paulson, Koji Matsuo

“…Abstract Introduction This study examined obstetric outcomes in patients diagnosed with uterine adenomyosis. Material and methods This historical cohort study queried the Healthcare Cost and Utilization Project's National Inpatient Sample. …”
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Genetic polymorphism of msp2 in Plasmodium falciparum isolates among asymptomatic malaria infections from two ecological settings in Cameroon by Aline G. Bouopda-Tuedom, Luc Abate, Brice L. Feufack-Donfack, Christelle M. Ngou, Albert N. Bayibeki, Carole E. Eboumbou Moukoko, Lawrence S. Ayong, Antoine Berry, Thierry Lefèvre, Isabelle Morlais, Sandrine E. Nsango

“…The msp2 IC/3D7 family was the most polymorphic and the most prevalent in both areas. Overall, more than 60% of the isolates had multiclonal infections. …”
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Effect of herbal medicine Bojungikgi-tang on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial by Boram Lee, Mi Mi Ko, You Mee Ahn, Hyo-Ju Park, So Young Jung, Hyun-A Jung, Hesol Lee, Pyung-Wha Kim, Yujin Choi, Kyungsun Han, Sarah Shin, Jeeyoun Jung

“…Among the serum cytokines, IL-1β significantly decreased only in the BJT group, while IL-4 and IL-17 significantly decreased in both groups, with a more pronounced reduction observed in the BJT group. …”
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Promoting recovery capital among college students in recovery on a campus developing a collegiate recovery program by Michael J. Broman, Michael J. Broman, Jhuma Acharya, Elizabeth A. Bowen, Emily Pasman, Erin Marks, Erin Marks, Jeffrey G. Kuentzel, Stella M. Resko, Stella M. Resko

“…However, recovery capital has received limited research attention in the context of collegiate recovery, and there has been little empirical evaluation of factors that might be linked with recovery capital among college students. As more collegiate recovery programs are developed to support students in recovery, these programs should implement features to augment students’ recovery capital.MethodsWe conducted a needs assessment on a campus with a newly developing collegiate recovery program. …”
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Integration of single-cell RNA and bulk RNA sequencing revealed malignant ductal cell heterogeneity and prognosis signatures in pancreatic cancer by Haiyang Du, Haiyang Du, Gao Si, Jiqing Si, Xuejie Song, Xuejie Song, Fuchun Si, Fuchun Si

“…Early diagnostic markers and an improved understanding of tumor-microenvironment interactions are essential for developing more effective therapies.MethodsWe analyzed 74 single-cell RNA sequencing (scRNA-seq) samples, performing unsupervised clustering and marker-gene expression profiling to define major cell types. …”
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Association between syphilis seroprevalence and age among blood donors in Southern China: an observational study from 2014 to 2017 by Feng Wang, Xiaobing Wu, Yang Guan, Jianbin Ye, Hanlin Fu, Chunlai Zhang, Lina Lan, Fengxin Wu, Fen Tang, Yumao Cai, Weiye Yu, Tiejian Feng

“…Objective This study investigated the association between syphilis seroprevalence and age among blood donors, and described the distribution of serological titres among syphilis-infected donors, aiming to confirm the syphilis epidemic characteristics and to promote effective interventions for older adults.Methods Data were obtained from the Shenzhen Programme for Syphilis Prevention and Control in 2014–2017. …”
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Systematic review and meta-analysis of the prevalence of oral cancer in Nigeria by Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Somtochukwu Anthonia Uzodufa, Abideen Salako, Folahanmi Tomiwa Akinsolu, Oliver Chukwujekwu Ezechi, Titilola Gbajabiamila, Francisca Nwaokorie, Omolola Titilayo Alade, George Uchenna Eleje, Joanne Lusher, Morẹ́nikẹ́ Oluwátóyìn Foláyan

“…The prevalence rate differed between gender populations, with more predilection to males (11%) than females (7%). …”
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Self-monitoring blood pressure in pregnancy: evaluation of women’s experiences of the BUMP trials by Alison Chisholm, Katherine L Tucker, Carole Crawford, Marcus Green, Sheila Greenfield, James Hodgkinson, Layla Lavallee, Paul Leeson, Lucy Mackillop, Christine McCourt, Jane Sandall, Hannah Wilson, Lucy C Chappell, Richard J McManus, Lisa Hinton

“…In the usual care arm, more women were already self-monitoring their blood pressure than expected. …”
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Culture Positivity and Antibiotic Resistance in Respiratory Intensive Care Patients: Evaluation of Readmission and Clinical Outcomes by Oral Menteş, Deniz Çelik, Murat Yildiz, Kerem Ensarioğlu, Maşide Ari, Mustafa Özgür Cırık, Abdullah Kahraman, Zehra Nur Şeşen, Savaş Gegin, Yusuf Taha Güllü

“…Male patients were significantly more likely to be readmitted (<i>p</i> = 0.008). …”
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Chronic stress is associated with altered gut microbiota profile and relevant metabolites in adolescents by Li Ying, Wang Yuhao, He Yafang, Lan Jiao, Dang Lina, Song Qinze, Yang Chenghai, Zhao Shaoxiong, Gu Yuexi, Shen Mingwang, Cai Zelin, Wang Chuangchuang, Guo Zihan, Liu Xin, Ma Lu, Zhang Lei

“…Results Adolescents experiencing high-chronic stress showed lower alpha diversity, differential beta diversity, and a more complicated microbial network compared to those experiencing lower stress. …”
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Psychological Profiles in Ulcerative Colitis and Crohn’s Disease: Distinct Emotional and Behavioral Patterns by Antonio Maria D’Onofrio, Eleonora Maggio, Valentina Milo, Gaspare Filippo Ferrajoli, Daniele Ferrarese, Daniela Pia Rosaria Chieffo, Massimiliano Luciani, Antonio Gasbarrini, Gabriele Sani, Franco Scaldaferri, Rosaria Calia, Giovanni Camardese

“…<b>Methods</b>: We enrolled 29 (44.61%) UC patients and 36 (55.39%) CD patients, all aged 18 years or older. …”
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Ruminococcus gnavus and Biofilm Markers in Feces From Primary Bile Acid Diarrhea Patients Indicate New Disease Mechanisms and Potential for Diagnostic Testing by Evette B.M. Hillman, Danielle Carson, Julian R.F. Walters, Martin Fritzsche, Ryan Mate, Katie E. Chappell, Elena Chekmeneva, Maria Gomez Romero, Stephen J. Lewis, Sjoerd Rijpkema, Elizabeth M.H. Wellington, Ramesh Arasaradnam, Gregory C.A. Amos

“…This study aimed to investigate fecal changes in well-defined subjects. Methods: Fecal samples were compared in BAD patients (n = 26), diagnosed by SeHCAT testing, and healthy controls (n = 21). …”
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Real-world clinical insights and aqueous humor biomarker analysis of diabetic macular edema subtypes classified by OCT following intravitreal injections by Liangzhang Tan, Shoukuan Liu, Wenrui Linghu, Yifeng Ke, Yongtao Li, Emmanuel Eric Pazo, Xinjun Ren

“…The variations in protein expression of aqueous humor suggested distinct pathological mechanisms for each DME subtype, laying the groundwork for more targeted treatment strategies.…”
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Reaction time variations in normal aging and elderly MCI patients under various cognitive load conditions by Yanfei Zhu, Yanfei Zhu, Zhuoming Chen, Zhengkun Shi, Zhengkun Shi, Junyi Chen, Junyi Chen, Qiankun Zuo, Qiankun Zuo, Zhi Yang, Wenjing Zhang, Wanting Li, Siyu Lu, Siyuan Peng, Lei Gou

“…ObjectivesTo compare reaction time parameters and accuracy rates between cognitively normal older adults and those with mild cognitive impairment (MCI) during the Stroop Color-Word Test, and to investigate how cognitive load modulates performance in MCI.MethodsSpeech audio samples (n = 1,920) were collected from 10 cognitively normal older adults and 10 MCI patients during Stroop task execution. …”
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Anatomical Variants in Pancreatic Irrigation and Their Clinical Considerations for the Pancreatic Approach and Surrounding Structures: A Systematic Review with Meta-Analysis by Juan José Valenzuela-Fuenzalida, Camila Ignacia Núñez-Castro, Valeria Belén Morán-Durán, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandra Suazo-Santibáñez, Alvaro Becerra-Farfan, Gustavo Oyanedel-Amaro, Alejandro Bruna-Mejias, Guinevere Granite, Daniel Casanova-Martinez, Juan Sanchis-Gimeno

“…To enhance outcomes, it is recommended to develop more accurate imaging tools for pre-surgical analysis, necessitating ongoing research in this area.…”
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Explaining and Analyzing the Effect of Brand Value Components on Medical Tourism Development: A Case Study of Ahvaz Metropolis by Majid Goodarzi

“…Thus, it is feasible to create a brand for these destinations using strategic programming methods. When selecting between a branded destination and its competitors, tourists are more likely to favor the branded option due to its stronger presence in their minds. …”
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Mass Media Exposure and Cervical Cancer Screening in Rural Sub‐Saharan Africa: A Multi‐Country Cross‐Sectional Analysis by Alex Bawuah, Vicky Q. Wang, Khadijat Adeleye, Edward Kwabena Ameyaw, Sanni Yaya

“…Women with exposure to mass media were significantly more likely to undergo screening. Specifically, women who watched television less than once a week (AOR = 1.22, 95% CI: 1.07–1.38) or at least once a week (AOR = 1.39, 95% CI: 1.26–1.53) had higher odds of being screened compared to those with no exposure to television. …”
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Fc-effector functional antibody assays for SARS-CoV-2 variants of concern by Xuemin Chen, Grace Li, Caroline Ciric, Theda Gibson, Larry J. Anderson, Larry J. Anderson, Christina A. Rostad, Christina A. Rostad

“…Combining Fc-mediated functional and neutralizing antibody assays provides a more comprehensive model for understanding vaccine-induced immunity and optimizing vaccination strategies.…”
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