Gut Microbiome and Metabolite Characteristics Associated With Different Clinical Stages in Non-Small Cell Lung Cancer Patients by Liu F, Lu X, Tang M, Chen Y, Zheng X

“…The current study seeks to explore the distinctive gut flora and metabolite profiles of NSCLC patients across varying TNM stages.Methods: The research team gathered stool samples from 52 patients diagnosed with non-small cell lung cancer (NSCLC) and 29 healthy individuals. …”
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CO42 | Oxidative stress may contribute to enhanced thrombopoiesis through miR-150: implications for aspirin response

“…Blood samples were collected at 10h (T10) and 24h (T24) following a witnessed ASA administration. …”
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Molecular characteristics and responses to EGFR tyrosine kinase inhibitors in non-small cell lung cancer patients with EGFR exon 19 insertions by Yang Li, Yunfeng Ni, Feng Lv, Yan Shi, Yedan Chen, Xiaoying Wu, Jiaohui Pang, Long Huang, Yang Shao, Tao Wang, Jie Min, Yang Song

“…Conclusions Comprehensive analysis of EGFR 19ins in lung cancer patients revealed genomic characteristics and clinical response, helping better inform clinical action and might facilitate the development of more precise therapeutic options for patients with these uncommon driver mutations.…”
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Tumor and peritumoral tissue hormonal background features in patients with rare types of endometrial cancer by E. M. Frantsiyants, V. A. Bandovkina, A. P. Menshenina, T. I. Moiseenko, M. A. Rogozin, Yu. A. Pogorelova, I. V. Kaplieva, E. I. Surikova, I. V. Neskubina, N. D. Cheryarina, E. V. Verenikina

“…In these regions, the concentration of E3 exceeded that of intact endometrium by a factor of more than five. A comparison of estrogen receptor (ER) levels revealed elevated levels in samples of the tumor, its perifocal zone, distant endometrium, and fallopian tubes. …”
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Occurrence and risk of human infection and antimicrobial susceptibilities of escherichia coli isolates from beef sold for human consumption in Jos metropolis, Plateau state Nigeria... by Yohanna Iliya, Jacob Kwada Paghi Kwaga, Grace Sabo Kia, Yakubu Gunya Dogonyaro Dashe, Godwin Ojonugwa Agada, Muhammad Shakir Balogun, Charles Michael Akatobi

“…We determined the prevalence and antimicrobial susceptibilities of Escherichia coli (E. coli) isolates from beef and assessed beef seller's practices and awareness of antimicrobial resistance (AMR) from Jos metropolis, Plateau State, Nigeria. Methods: We recruited 114 beef sellers and collected beef samples for the study. …”
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Sociodemographic factors associated with alcohol consumption among men in Gabon: insights from the Gabon demographic and health survey of 2019–2021 by Gosa Mankelkl, Beletu Kinfe

“…The primary driver of alcohol consumption is likely its capacity to elevate mood and alleviate stress. More than 200 medical conditions, including liver diseases, traffic accidents, violence, cancer, heart disease, suicide, tuberculosis, and HIV/AIDS, have been causally associated with alcohol consumption. …”
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Non-COVID-19 mortality among older people or with chronic conditions during year 2020 in France: a nationwide cohort study by Panayotis Constantinou, Charline Jean, Florence Canoui-Poitrine, Emilie Ferrat

“…Our objective was to assess non-COVID-19 mortality (referred to as “non-covid”) during year 2020 in a population of older people or with chronic conditions in France. Methods A nationally representative sample of adults aged 70 or more or with chronic conditions was followed from the beginning of the first lockdown to 31/12/2020. …”
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Predictors of Medication Non-Adherence Among Hepatitis B Patients in South Sudan: A Health-Facility-Based Cross-Sectional Study by Afolabi IB, Aremu AB, Koryom MJP, Buh A, Bainbridge SA, Phillips KP

“…The patients demonstrated inadequate HBV information (4.33± 1.93), low motivation (8.20± 2.69), and inadequate behavioral skills toward medication adherence (8.45± 2.99), as measured on their respective rating scales. Further, more than two-thirds of the patients (70.2%) were HBV medication non-adherent. …”
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Prevalence of Toxoplasmosis in Blood Donors: A Systematic Review and Meta-Analysis by Amna Iqbal Butt, Ammara Riaz, Fariha Salman, Laila Afzal, Sana Qanber Abbasi, Rabiah Mahwish

“…A total of 15 cross-sectional studies reporting the prevalence of toxoplasmosis among blood donors, involving any serological method for detecting total antibodies or IgG only, having a sample size of more than 100 and free full text available, were included. …”
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The Prospective role of lapatinib as an adjuvant therapy in prevalent cancers: Insights from in silico analysis targeting EGFR and HER2 by Behnaz Dolatabadi, Maryam Peymani, Leila Rouhi, Ali Salehzadeh, Kiavash Hushmandi, Mehrdad Hashemi

“…Results: The findings clearly indicated a significant increase in the expression levels of HER2 and EGFR in cancers such as kidney, lung, breast, bladder, pancreas, head and neck, stomach, and endometrial, both at the mRNA and protein levels (p-value <0.01). Additionally, more than 30 % of samples in some cancers showed a twofold increase in HER2 or EGFR expression. …”
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Prevalence and risk factors for lameness in dairy cattle on selected farms located in Dessie and Kombolcha, Northeast Ethiopia by Hasen Ahimed Mekonin, Abadi Amare Reda, Abadi Amare Reda, Alula Alemayehu Assen, Alula Alemayehu Assen, Awol Mohammed Assen, Awol Mohammed Assen

“…Furthermore, the animals on farms with a history of lameness (OR = 10.0, 95%CI = 2.87–37.4, p = 0.001) were more likely to be clinically lame.ConclusionLameness was strongly associated with the middle and late stages of lactation, particularly on farms with a previous history of lameness. …”
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Neonatal reticulocyte count during the early postnatal period by Mika Yamada, Mina Chishiki, Yuji Kanai, Aya Goto, Takashi Imamura

“…All blood samples were collected within 3 h after admission. …”
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Effects of clear aligners treatment in growing patients: a systematic review by Vincenzo D’Antò, Vittoria De Simone, Silvia Caruso, Paolo Bucci, Rosa Valletta, Roberto Rongo, Rosaria Bucci

“…Nevertheless, additional high-quality studies are required to formulate more reliable conclusions.Systematic Review Registrationhttps://osf.io/wmerq.…”
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100% oxygen mobilizes stem cells and up-regulates MIF and APRIL in humans: a new point on the hormetic dose curve by Kent J. MacLaughlin, Gregory P. Barton, Julia E. MacLaughlin, Jacob J. Lamers, Matthew D. Marcou, Matthew J. O’Brien, Rudolf K. Braun, Marlowe W. Eldridge

“…Conversely CD45−/CD34+/CD133+, CD45-/CD34+/CD133− and CD45−/CD34−/CD133+ phenotypes were downregulated suggesting differentiation into more mature phenotypes. The CD133+ phenotype exhibited a maturing from CD45− to CD45dim stem cells. …”
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Clinical Characteristics of 76 Patients with IgG4-Related Hypophysitis: A Systematic Literature Review by Yujuan Li, Hua Gao, Zhen Li, Xinxin Zhang, Yizhi Ding, Fengao Li

“…Further clinical studies with larger sample sizes are warranted.…”
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Echocardiographic Assessment of Cardiac Structure and Function of Centenarians: A Systematic Review by Andrea Sonaglioni, Gian Luigi Nicolosi, Giovanna Elsa Ute Muti-Schünemann, Alessio Polymeropoulos, Michele Lombardo, Paola Muti

“…These studies analyzed limited sample sizes of centenarians using different methodologies. …”
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Adaptive measurement of cognitive function based on multidimensional item response theory by Robert D. Gibbons, Diane S. Lauderdale, Robert S. Wilson, David A. Bennett, Tesnim Arar, David A. Gallo

“…We present results for a prototype CAT (pCAT‐COG) for assessment of global cognitive function. METHODS We sampled items across five cognitive domains central to neuropsychological testing (episodic memory [EM], semantic memory/language [SM], working memory [WM], executive function/flexible thinking, and processing speed [PS]). …”
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The Effect of Transfusion and Hypoxia on Cells in an in vitro Model of the Neurovascular Unit by A. A. Ivkin, E. V. Grigoriev, E. D. Khilazheva, A. V. Morgun

“…Intensive SIR demonstrated short-term but more deleterious than hypoxia, effect on cells in the NVU model. …”
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Sleep, Health Care–Seeking Behaviors, and Perceptions Associated With the Use of Sleep Wearables in Canada: Results From a Nationally Representative Survey by Karianne Dion, Meggan Porteous, Tetyana Kendzerska, Ashley Nixon, Elliott Lee, Massimiliano de Zambotti, Sheila N Garland, Mandeep Singh, Gino De Luca, Samuel Gillman, Andrée-Ann Baril, Dave Gallson, Rebecca Robillard

“…ObjectiveThis study aims to (1) determine the prevalence and sociodemographic predictors of using sleep wearables in Canada, (2) evaluate the perceived effects of wearable use on sleep and stress, (3) compare sleep and health care–seeking behaviors in users and nonusers, and (4) investigate the moderating effects of wearable use on the association between sleep and anxiety. MethodsAn online survey investigating sleep and mental health was distributed to a representative sample of 1200 Canadians. …”
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Occupational health complaints and demographic features of farmers exposed to agrochemicals during agricultural activity by Dhananjayan Venugopal, Ravichandran Beerappa, Deepika Chauhan, Panjakumar Karunamoorthy, Mala Ambikapathy, Thamaraikannan Mohankumar, Avinash Gaikwad, Shridhar Kondhalkar

“…Health complaints were significantly more common in the exposed group: 35% reported fatigue (compared to 20% in controls, χ² = 5.51, p = < 0.05). …”
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