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15541
The Effects of COVID-19 on Financial Distress and Tax Avoidance
Published 2025-03-01“…The research sample consisted of 162 firms listed on the Tehran Stock Exchange (TSE) from 2017 to 2022. …”
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15542
Stress in individuals with noncommunicable diseases: ESSE-RF and ESSE-RF2 data
Published 2024-11-01“…To determine the level and prevalence of stress in individuals with noncommunicable diseases (NCDs).Material and methods. Representative samples of the population aged 25-64 years from 17 regions of the Russian Federation (n=27950) were included, examined within the ESSE-RF and ESSE-RF2 studies. …”
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15543
INBRX-106: a hexavalent OX40 agonist that drives superior antitumor responses via optimized receptor clustering
Published 2025-05-01“…Clinical pharmacodynamic analysis in blood samples from patients treated with INBRX-106 showed heightened T-cell activation and proliferation, particularly in central and effector memory subsets, validating our preclinical findings.Conclusions Our data establish hexavalent INBRX-106 as a differentiated and more potent OX40 agonist, showcasing its ability to overcome the limitations of conventional bivalent therapies by inducing superior receptor clustering and multimeric engagement. …”
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15544
Investigation of the Protective Effects of Dexmedetomidine, Midazolam, Propofol, and Intralipid on Oxidative Stress and Inflammation in Rats with Lidocaine-Induced Toxicity
Published 2025-01-01“…Despite an increase in oxidative stress in brain tissue samples across all groups, it was found that all groups exhibited antioxidant protective effects (p < 0.05). …”
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15545
Identification of an elusive SERPING1 deletion in a family with hereditary angioedema type I utilizing soft clipping
Published 2025-04-01“…We further investigated a family with laboratory-confirmed HAE type I despite previous negative genetic test results for SERPING1 mutations.MethodsWe consented and collected whole blood samples from three family members with clinical diagnoses of HAE. …”
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15546
Relationship between personal anxiety and genes associated with eating disorders in women aged 45-64
Published 2024-10-01“…To study the possible relationship between personal anxiety and polymorphic variants of genes associated with eating disorders (rs17782313 MC4R, rs1800497 DRD2, rs9939609 FTO) in women aged 45-64 in Novosibirsk.Material and methods. A random representative sample of women aged 45-64 years (n=1074, mean age, 54,27±0,2 years) was examined in 2003-2005 at the Research Institute of Internal and Preventive Medicine, a branch of the Institute of Cytology and Genetics, within the Health, Alcohol and Psychosocial Factors In Eastern Europe (HAPIEE) project. …”
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15547
High salt intake in the Russian population: prevalence, regional aspects, associations with socio-demographic characteristics, risk factors and diseases. Results of epidemiological...
Published 2023-12-01“…To study the characteristics of high salt intake in Russian and Moscow populations according to epidemiological studies.Material and methods. Data from representative samples of adult population aged 25-64 years (n=21922, 8372 men and 13550 women) from Russian 13 regions and persons aged >18 years (n=4063, 1662 men and 2401 women) from Moscow were used. …”
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15548
Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context
Published 2025-09-01“…Comparative evaluations of molecular diagnostic assays in high-burden settings are essential for informing clinical decision-making for DR-TB treatment. Methods: The Seq&Treat clinical study previously evaluated the performance of two targeted next-generation sequencing (tNGS) workflows, GenoScreen Deeplex Myc-TB and Oxford Nanopore Technologies Tuberculosis Drug Resistance Test, on direct sediment samples from persons at risk for DR-TB. …”
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15549
PhyloFunc: phylogeny-informed functional distance as a new ecological metric for metaproteomic data analysis
Published 2025-02-01“…We provide PhyloFunc as an open-source Python package (available at https://pypi.org/project/phylofunc/ ), enabling efficient calculation of functional beta-diversity distances between a pair of samples or the generation of a distance matrix for all samples within a dataset. …”
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15550
The preventive effect of sodium-glucose co-transporter-2 inhibitors on atrial fibrillation and atrial flutter in patients with chronic kidney disease: a meta-analysis
Published 2025-05-01“…Subgroup analysis based on sample size and follow-up duration showed that SGLT2i reduced the risk of AF in trials with sample size more than 1,000 and follow-up duration longer than 2 years (0.59% vs. 0.80%; RR 0.74, 95% CI 0.55–0.99, P = 0.04). …”
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15551
The association between gut microbiota composition and cardiometabolic parameters in healthy adults
Published 2025-08-01“…Fecal and blood samples were collected from all participants. Bacterial DNA from fecal samples was extracted, and the full-length 16 S rRNA was amplified. …”
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15552
Immunological characterization of pleural effusions in pediatric patients
Published 2024-12-01“…This study provides the first comprehensive immunological characterization of paired blood and pleural effusion samples, utilizing combined cell and cytokine analyses in pediatric patients undergoing cardiac surgery.MethodsIn 30 pediatric patients (median age: 22 months) with pleural effusion after cardiac surgery for congenital heart defects, corresponding peripheral blood and pleural effusion samples were analyzed for their immune response. …”
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15553
Numerical and experimental evaluation of shear strength and consolidation properties of cohesive soils in high water table areas
Published 2025-03-01“…The numerical results from PLAXIS offered a more accurate understanding of soil behavior compared to the traditional Meyerhof and Vesic methods, highlighting the necessity of integrating advanced numerical techniques with conventional approaches. …”
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15554
The Field Assessment of Quiescent Egg Populations of <i>Aedes aegypti</i> and <i>Aedes albopictus</i> during the Dry Season in Tapachula, Chiapas, Mexico, and Its Potential Impact...
Published 2024-10-01“…Evolutionary characteristics for the two species including partial egg hatching, ambient-regulated quiescence, the ability of the embryo to survive for a more extended period intra-seasonally, the egg sticking to inner container walls, demands urgent operational research to achieve successful egg-proof larval container methods.…”
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15555
Colostrum-Derived Melatonin Plus PEG Microspheres Modulate the Oxidative Metabolism of Human Colostrum Phagocytes
Published 2025-01-01“…Therefore, the objective of this study was to extract melatonin from human colostrum, develop and characterize PEG microspheres with the extracted melatonin adsorbed onto them, and evaluate the effects of this system on the oxidative metabolism of colostrum phagocytes. Methods: Thirty colostrum samples were collected; ten were used for melatonin extraction, while twenty were used to obtain phagocytes. …”
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15556
Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia
Published 2020-04-01“…However, resistance to GC is observed more frequently than resistance to other chemotherapy agents in patients with ALL relapse. …”
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15557
Atlantic mackerel population structure does not support genetically distinct spawning components [version 2; peer review: 1 approved, 2 approved with reservations]
Published 2025-01-01“…Such reference genome was used to map Restriction-site-associated sequencing (RAD-seq) reads for SNP discovery and genotyping in more than 500 samples distributed along the species range. …”
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15558
Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury
Published 2024-06-01“…Thirty percent of adults with MH-AKI, and especially those who are older, show progression to chronic kidney disease. Methods: We evaluated the immunohistopathologic characteristics of renal biopsy samples from pediatric patients with MH-AKI IgAN and controls, using Berlin Blue to identify iron, CD163 (a hemoglobin-scavenging receptor), and CD68 (a total macrophage marker), then compared the findings against the clinical characteristics of the patients. …”
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15559
BRAF Mutations in an Italian Regional Population: Implications for the Therapy of Thyroid Cancer
Published 2015-01-01“…The presence of the BRAF V600E mutation may suggest a more aggressive surgical approach. BRAF K601E mutation did not correlate with malignancy indexes.…”
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15560
Fast and Flexible Inference Framework for Continuum Reverberation Mapping Using Simulation-based Inference with Deep Learning
Published 2024-01-01“…Using simulated light curves, we find SBI can produce more accurate SMBH parameter estimation with 10 ^3 –10 ^5 times speed up in inference efficiency compared to traditional methods. …”
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