Trajectories of medical students’ empathy nowadays: a longitudinal study using a comprehensive framework of empathy by Valerie Carrard, Céline Bourquin, Sylvie Berney, Setareh Ranjbar, Katja Schlegel, Jacques Gaume, Pierre-Alexandre Bart, Marianne Schmid Mast, Martin Preisig, Alexandre Berney

“…Abstract Background For more than a decade, the literature has been dominated by the notion that medical students may paradoxically lose their empathy during medical school. …”
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A real-world study of the optimal cut-off value for vancomycin trough concentration associated with outcomes in children infected with drug-resistant Gram-positive bacteria by Yinghui Yan, Manli Wang, Mi Zhou, Jingxing Yang, Jingxing Yang, Zengyan Zhu, Fengjiao Wang

“…BackgroundDue to a lack of studies on the relationship between vancomycin trough concentration and clinical outcomes in pediatric patients, there is insufficient evidence to provide a unified standard for vancomycin trough concentration for children.MethodsWe retrospectively analyzed the data of drug-resistant Gram-positive bacteria isolated from human germfree samples of 66 children diagnosed as definite infectious diseases. …”
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Evaluating adherence in an active-controlled HIV pre-exposure prophylaxis trial (PrEPVacc) to inform the estimation of HIV incidence in a counterfactual placebo arm by Sheila Kansiime, Christian Holm Hansen, Henry Bern, Julie Fox, David Dunn, Eugene Ruzagira, Richard Hayes, Sheena Mc Cormack, on behalf of the PrEPVacc study team

“…Males, Verulam and Mbeya participants, those ≥ 25 years, not single, subsistence fisheries workers, and those who had any STI at baseline were more likely to have higher adherence. Of those assessed at visit 6, 29% were identified as white coat dosing. …”
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Targeted probiotic therapy in irritable bowel syndrome: a clinical evaluation on Clostridium butyricum CBM588 and Bifidobacterium longum W11 by Alexander Bertuccioli, Alexander Bertuccioli, Davide Sisti, Nadia Lazzerini, Chiara Maria Palazzi, Giordano Bruno Zonzini, Giordano Bruno Zonzini, Mirko Ragazzini, Annalisa Belli

“…Future studies with larger sample sizes and longer follow-up periods are recommended to confirm and expand these findings.…”
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Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): a study protocol for a multicentre longitudinal interventional study using mobile heal... by Milada Cvancarova Småstuen, Ingvild Vistad, Torbjørn Wisløff, Kristina Lindemann, Lonneke V van de Poll-Franse, Mette Skorstad, Sveinung Berntsen, Ingrid Demmelmaier

“…Introduction The number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. …”
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Microsatellite Status, Tumor Budding, CD3 and CD8 T Cell Densities in Relation to Invasiveness, Lymph Node Involvement in Colorectal Adenocarcinoma by Rebecca Noerjani Angka, Aru Wisaksosno Sudoyo, Nurjati Chairani Siregar, Wifanto Saditya Jeo, Melva Louisa, Demak Lumban Tobing

“…In this study association of TB, T cell densities and loss of MMR protein were examined to see the association with differentiation, tumor location, invasiveness and lymph node invasiveness. Methods: A retrospective cohort study was conducted using 68 CRC Formalin Fixed Paraffin Embedded samples from patients who underwent removal surgeries with the diagnosis of adenocarcinoma not otherwise specified. …”
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MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment by Tao Jiang, Jingcheng Zhang, Sicheng Zhao, Mingsi Zhang, Yunhai Wei, Xiaojuan Liu, Shuo Zhang, Wei Fan, Yueying Liu, Yuanlin Lv, Guangji Zhang

“…Results The expression of MCT4 is upregulated in gastric cancer patients, and the upregulation is more significant than that in patients with gastric cancer metastasis. …”
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Near vision assessment for adults using the NIH Toolbox by John-Christopher A. Finley, Jerry Slotkin, Cindy J. Nowinski, Cindy J. Nowinski, Katy Bedjeti, Nicholas Volpe, Sandra Weintraub, Sandra Weintraub, Richard Gershon

“…This study is the first to report the psychometric properties of the NIH Toolbox Near Visual Acuity Test in a sample of community-dwelling middle-aged and older adults.MethodsNinety-eight adults (ages 40–81) completed the tablet-based near vision test and the gold standard chart-based near vision test. …”
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Enhanced associations between subjective cognitive concerns and blood-based AD biomarkers using a novel EMA approach by Ángel García de la Garza, Caroline Nester, Cuiling Wang, Jacqueline Mogle, Nelson Roque, Mindy Katz, Carol A. Derby, Richard B. Lipton, Laura Rabin

“…Conclusions EMA provides a more dynamic and potentially sensitive method for detecting early AD risk compared to traditional SCC assessments. …”
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Risk of Osteoporotic Fractures among Patients with Thyroid Cancer: A Nationwide Population-Based Cohort Study by Eu Jeong Ku, Won Sang Yoo, Yu Been Hwang, Subin Jang, Jooyoung Lee, Shinje Moon, Eun Kyung Lee, Hwa Young Ahn

“…We aimed to investigate the risk of osteoporotic fractures in patients with thyroid cancer compared to that in a matched control group. Methods This retrospective cohort study included 2,514 patients with thyroid cancer and 75,420 matched controls from the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC, 2006–2019). …”
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Study protocol for a multimethod investigation of the development of social and nonsocial reward responsivity and depression in autistic adolescents: Reward and Depression in Autis... by Jessica M. Schwartzman, Autumn Kujawa, Shafali S. Jeste, Blythe A. Corbett, Wenyi Xu, Alexa D. Monachino, Marian A. Castro, Katia Cardenas-Quintero, Anh Dao, Ramon Durazo-Arvizu, Santiago Morales

“…Abstract Background Autistic adolescents are more likely to experience depression than their non-autistic peers, yet risk factors for depression in autistic adolescents are not well understood. …”
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Evaluation of the natural killer cell subsets and their relationship with serum interferon gamma and vitamin D levels in women with stages III and IV endometriosis: A case-control... by Samira Najafi Chamgordani, Nafiseh Esmaeil, Maryam Hashemi, Afshin Amari, Maryam Seyedtabib, Mehri Ghafourian

“…Conclusion: The study of NK cell subsets and their related factors can be useful in assessing and treating women suffering from endometriosis. However, more comprehensive studies are required to draw definitive conclusions about these observations.…”
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Sex differences in inflammatory markers in bipolar disorder by Yanlin Liu, Hui Xin Ng, Ashley Sutherland, Soohyun Joe, Benchawanna Soontornniyomkij, Federica Klaus, Lisa T. Eyler

“…Conclusions: Men had higher TNF-α serum levels than women; this difference was more pronounced in BD than HC. CRP was elevated in BD compared to HC men. …”
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Infertility treatments and risk of breast benign diseases: a case‒control study by Ashraf Moini, Sadaf Alipour, Zahra Zandi, Arezoo Maleki-Hajiagha, Ladan kashani, Fatemeh Shakki katouli, Maryam Farid Mojtahedi, Leila Bayani, Mahboubeh Abedi

“…Therefore, we consider it essential to carry out more extensive, detailed, and prospective studies to distinguish the association of BBDs with different infertility treatments and medications.…”
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Low Birth Weight and Related Metabolic Risk Factors, Cardio-Respiratory Fitness and Physical Activity in Adolescents by Aristides M. Machado-Rodrigues, Cristina Padez, Daniela Rodrigues, Luís P. Mascarenhas, Nuno Borges, Cátia Maia, Liliana C. Baptista, Helder Miguel Fernandes, Neiva Leite

“…Thus, this study analysed the interrelationship among MRF, LBW, and behavioural factors in adolescents. Methods: The sample of the present cross-sectional study comprised 491 youth (229 males, 262 females) aged 14–17 years. …”
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Association of Acute Venous Thromboembolism With In‐Hospital Outcomes of Coronary Artery Bypass Graft Surgery by Muhammad S. Panhwar, Mahazarin Ginwalla, Ankur Kalra, Tanush Gupta, Dhaval Kolte, Sahil Khera, Deepak L. Bhatt, Joseph F. Sabik

“…We sought to investigate the postoperative incidence and outcomes of CABG patients using a large national inpatient database. Methods and Results We utilized the 2013 to 2014 National Inpatient Sample to identify all patients >18 years of age who underwent CABG (without concomitant valvular procedures), and had VTE during the hospital stay. …”
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Intra-tumoral spatial heterogeneity in breast cancer quantified using high-dimensional protein multiplexing and single cell phenotyping by Alison M. Cheung, Dan Wang, Mary Anne Quintayo, Yulia Yerofeyeva, Melanie Spears, John M. S. Bartlett, Lincoln Stein, Jane Bayani, Martin J. Yaffe

“…The extent of variation of biomarker expression in the cancer cells, distribution of cell types in the local tumor microenvironment and their spatial arrangement could impact on diagnosis, treatment planning and subsequent response to treatment. Methods Using quantitative multiplex immunofluorescence (MxIF) imaging, we assessed the level of variations in biomarker expression levels among individual cells, density of cell cluster groups and spatial arrangement of immune subsets from regions sampled from 38 multi-focal breast cancers that were processed using whole-mount histopathology techniques. …”
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Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement Outcomes in Left Ventricular Assist Device Patients with Aortic Insufficiency by Aniket S Rali, Siva S Taduru, Lena E Tran, Sagar Ranka, Kelly H Schlendorf, Colin M Barker, Ashish S Shah, JoAnn Lindenfeld, Sandip K Zalawadiya

“…Limited data are available on outcomes with either SAVR or TAVR for the management of post-LVAD AI. Methods: The National Inpatient Sample data collected for hospital admissions between the years 2015 and 2018 for patients with pre-existing continuous-flow LVAD undergoing TAVR or SAVR for AI were queried. …”
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Soil Erosion by Wind Storms in a Pampean Semi-Arid Region of Argentina: An Environmental Magnetism Approach by Brenda Alba, Marcos A. E. Chaparro, Andrea A. Bartel, Harald N. Böhnel, Silvia B. Aimar

“…Environmental magnetism methods offer a practical approach to assessing soil redistribution by wind and water. …”
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Evaluation of Medical School Students in Terms of Attention Deficit Hyperactivity Disorder and Emotional Regulation Difficulties by Ayşe Akan, Engin Burak Selçuk, Burcu Kayhan Tetik, Mustafa Akan, Ahmet Kadir Arslan

“…In addition, suicide attempts, forensic event history, and class failure were significantly more frequent in the HP-ADHD group than in the WO-ADHD group (p<0.001, p=0.043, p=0.024 respectively). …”
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