From genes to therapy: a lipid Metabolism-Related genetic risk model predicts HCC outcomes and enhances immunotherapy by Lei Xu, Ting Xiao, Tengfei Chao, Huihua Xiong, Wei Yao

“…However, they responded more favorably to immune checkpoint inhibitor (ICB) therapy. …”
Get full text

C-reactive Protein, Absolute Neutrophil Count, and Appendix Wall Thickness in Predicting Appendicitis Severity and Outcomes: A Retrospective Study by Waheeb Radman Al-Kubati

“…Patients with elevated CRP (>100 mg/L), appendix wall thickness (>7 mm), and ANC (>12,000 cells/μL) were more likely to develop complications, such as perforation and abscess formation (P < .001). …”
Get full text

Blood pressure control in primary care patients with arterial hypertension: analysing the Hypertension Register data by O. M. Posnenkova, A. P. Kiselev, V. I. Gridnev, V. A. Schwartz, P. Ya. Dovgalevskyi, E. V. Oshchepkova

“…Patients with optimal BP control were characterised by a more severe clinical course, as well as by a wider scope and higher frequency of diagnostic and therapeutic procedures. …”
Get full text

Costs and Outcomes of Clostridioides difficile Infections in Germany: A Retrospective Health Claims Data Analysis by Katharina Schley, Kirstin Heinrich, Jennifer C. Moïsi, Dennis Häckl, Dominik Obermüller, Gordon Brestrich, Christof von Eiff, Thomas Weinke

“…Since no recent data were available from Germany on the medical costs and clinical outcomes of Clostridioides difficile infections (CDI), this study assessed the economic burden of CDI and all-cause mortality in adults in Germany. Methods A retrospective cohort study was conducted using a large, anonymized administrative health claims research database from Germany from which an age- and sex-representative sample of 4 million insured persons covered by approximately 60 statutory health insurances was extracted. …”
Get full text

A novel machine learning methodology for the systematic extraction of chronic kidney disease comorbidities from abstracts by Eszter Sághy, Mostafa Elsharkawy, Frank Moriarty, Sándor Kovács, István Wittmann, Antal Zemplényi, Antal Zemplényi

“…A comprehensive understanding of CKD comorbidities could lead to the identification of risk-groups, more effective treatment and improved patient outcomes. …”
Get full text

The Accuracy and Trueness of Intraoral Scanners in Neonates With Cleft Lip and Palate: A Comparison of 3D Digital Models by Piyapat Chatborirak, Krisadi Phannarus, Pimsiri Kanpittaya, Pintu-on Chantarawaratit

“…Introduction and aims: Intraoral scanners have recently emerged as a safer and more convenient alternative to traditional impression materials for capturing alveolar morphology in patients with cleft anomalies. …”
Get full text

Relationships between Sleep Duration, Timing, Consistency, and Chronotype with Myopia among School-Aged Children by Rong Li, Yiting Chen, Anda Zhao, Lili Huang, Zichong Long, Wenhui Kang, Yong Yin, Shilu Tong, Shenghui Li

“…All these findings were also similarly observed in the matching sample. Conclusions. Multiple dimensions of sleep were involved in childhood myopia. …”
Get full text

The effect of ischemic preconditioning on the cardiac autonomic nervous system after exercise: A systematic review and meta-analysis by Chuan qiu shui Wang, Kun Wang, Hengxu Liu, Shi qi Liu, Yi Yang, Jiong Luo

“…Limitation: Given the limited number of included studies, the small sample size, and the unclear definition of some experimental procedures, it is essential to design more rigorous and comprehensive high-quality randomized controlled trials (RCTs) in the future to investigate the effects of ischemic preconditioning on cardiac autonomic control nerves following exercise. …”
Get full text

Psychometric properties of the German version of the Traumatic Grief Inventory-Self Report Plus (TGI-SR+) by Julia Treml, Viktoria Schmidt, Elmar Braehler, Matthias Morfeld, Anette Kersting

“…The study aimed to evaluate the psychometric properties of the German version of the Traumatic Grief Inventory Self-Report Plus (TGI-SR+), a self-report measure to assess PGDICD-11 and PGDDSM-5-TR symptoms.Methods: Out of a representative sample of the German general population (N = 2509), 1062 reported a significant loss and completed questions about sociodemographic and loss-related variables, the TGI-SR+, and a measure of health-related quality of life.Results: Item analyses demonstrated good item characteristics. …”
Get full text

THE ROLE OF ANTI-VEGF THERAPY IN IMPROVING THE EFFICACY OF SURGICAL TREATMENT OF SECONDARY NEOVASCULAR GLAUCOMA by Uliana Sydorchuk, Ihor Novytskyy

“…To investigate the fluctuation of vascular endothelial growth factor concentration after intravitreal ranibizumab injections and to evaluate the effect of anti-VEGF therapy on the outcome of surgical treatment of NVG. Materials and Methods. The study included 25 patients (25 eyes) with NVG who underwent surgery due to IOP non-compensation (more than 26 mm Hg) on maximal hypotensive therapy. …”
Get full text

Effect of personality characteristics on perception of tooth whitening outcome in young adults in long-term: a randomised, double-blind, placebo controlled trial by Batinić Marija, Kovačević Pavičić Daniela, Šango Ana, Brumini Martina, Špalj Stjepan

“…Data were analyzed using analysis of variance with Bonferroni post hoc tests and independent samples t-tests. Results The experimental group showed a significantly greater improvement in tooth color shortly after treatment compared to the control group. …”
Get full text

Health Effects of Heavy Metal Exposure Among E-waste Workers and Community-dwelling Adults in Thailand: A Cross-sectional Study by Chonyitree Sangwijit, Parichat Ong-artborirak, Warangkana Naksen, Kraiwuth Kallawicha, Pallop Siewchaisakul

“…Factors including primary education level or below, smoking, cleaning the house more than 3 times weekly, and PSQ were significantly linked to depression. …”
Get full text

Effects of exercise interventions on cognitive function in patients with cognitive dysfunction: an umbrella review of meta-analyses by Guangyao Sun, Xingyi Ding, Zhong Zheng, Hongtao Ma

“…Aerobic exercise (MD 2.95) was more effective for AD, while mind–body exercises (MD 1.68) benefitted PD patients. …”
Get full text

SFG-Net: A Scattering Feature Guidance Network for Oriented Aircraft Detection in SAR Images by Qingyang Ke, Youming Wu, Wenchao Zhao, Qingbiao Meng, Tian Miao, Xin Gao

“…A series of experiments was conducted on the CSAR-AC dataset to validate the effectiveness and generalizability of the proposed method.…”
Get full text

Machine Learning Reveals Microbial Taxa Associated with a Swim across the Pacific Ocean by Garry Lewis, Sebastian Reczek, Osayenmwen Omozusi, Taylor Hogue, Marc D. Cook, Jarrad Hampton-Marcell

“…<b>Purpose:</b> This study aimed to characterize the association between microbial dynamics and excessive exercise. <b>Methods:</b> Swabbed fecal samples, body composition (percent body fat), and swimming logs were collected (n = 94) from a single individual over 107 days as he swam across the Pacific Ocean. …”
Get full text

The Relationship Between Vitamin D and Euthyroid Sick Syndrome in Hospitalized Solid Cancer Patients: A Retrospective Study by Mehmet Emin Buyukbayram, Zekeriya Hannarici, Aykut Turhan, Alperen Akansel Çağlar, Pınar Çoban Eşdur, Mehmet Bilici, Salim Başol Tekin

“…Conclusion: Euthyroid sick syndrome may be relatively common among patients with HSC and is more frequently observed in those hospitalized for supportive care. …”
Get full text

Impact of Burdizzo and Surgical Castration on Immune and Oxidative Stress Markers in Cattle by Thanyakorn Chalalai, Piyarat Srinontong, Worapol Aengwanich, Kanticha Srisila, Sudarat Promkrathok, Mookdawan Sununta, Bhuripit Saraphol, Zhiliang Wu

“…Both methods caused alterations in CD3⁺CD4⁺ and CD3⁺CD8⁺ T-cell counts, while Burdizzo castration induced longer-lasting immune activation. …”
Get full text

Influence of deep marginal elevation on the marginal adaptation and fracture resistance of zirconia endocrowns constructed on endodontically treated premolar teeth: in vitro study by Sara Tamimi, Huda I. Mostafa, Menna S. Ali, Hayam M. Tawfik

“…Catastrophic failure (fracture below the CEJ) was more frequently observed in both groups. Conclusion DME has no significant effect on either marginal adaptation or fracture resistance of premolars restored with multi-layered translucent zirconia endocrowns. …”
Get full text

Factors associated with the unwillingness of Jordanians, Palestinians and Syrians to be vaccinated against COVID-19. by Sima Zein, Sarah B Abdallah, Ahmed Al-Smadi, Omar Gammoh, Wajdy J Al-Awaida, Hanan J Al-Zein

“…Representative sample of 8619 adults residing in Jordan, West Bank, and Syria, completed the survey via the Web or via telephone interview. …”
Get full text

Advantages of a New Taq DNA Polymerase in Multiplex PCR and Time-Release PCR by C. Kebelmann-Betzing, K. Seeger, S. Dragon, G. Schmitt, A. Möricke, T.A. Schild, G. Henze, B. Beyermann

“…Extensive diagnostic and scientific investigations are often restricted by limited availability of material. Therefore, methods like multiplex PCR strategies are needed to conserve as much sample as possible. …”
Get full text