Approaches to automation of the preanalytical phase of large-scale research in the biobank of the National Medical Research Center for Therapy and Preventive Medicine of the Minist... by M. S. Pokrovskaya, A. L. Borisova, V. A. Kondratskaya, I. A. Efimova, A. I. Ershova, O. M. Drapkina

“…To create and validate an algorithm for automatic aliquoting of serum and plasma samples for biobanking as part of a large-scale study.Material and methods. …”
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HMCFormer (hierarchical multi-scale convolutional transformer): a hybrid CNN+Transformer network for intelligent VIA screening by Bo Feng, Chao Xu, Zhengping Li, Chuanyi Zhang

“…Visual inspection with acetic acid (VIA) screening based on artificial intelligence-assisted diagnosis can provide a cheap and rapid screening method. This will attract more low-income women to volunteer for regular cervical cancer screening. …”
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Monitoring and detection of genetically modified soybean in animal feed using real-time PCR (2019-2024) by Pandžić Katarina, Steiner Zvonimir, Radović Čedomir, Duka Ksenija, Gantner Vesna

“…This study focuses on the presence and diversity of GM sequences in soybean meal samples collected between 2019 and 2024. A total of 94 samples were analyzed using sensitive molecular methods, including qualitative and quantitative PCR (Real-time PCR), in accordance with validated international protocols. …”
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Calibration of Energy Simulation Models on a Building Stock Level using Actual Energy Consumption Data by Paula van den Brom, Laure Itard, Henk Visscher

“…This method has the potential to make building simulation models a more reliable tool for policymakers. …”
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The effect of urban sprawl in emerging of transportation flows and urban air pollution in Tehran metropolitan region

“…The article studied the role of transportation in emergence of urban air pollution in Tehran metropolitan region, have population more than 15.98 million. The method of this paper is of analytical and is based on the secondary data and traditions of the Quantitative research methodology. …”
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Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment by Dongli Tian, Jiaying Li, Linfeng Zou, Min Lin, Xiaoxiao Shi, Yuting Hu, Jiaxin Lang, Lubin Xu, Wenling Ye, Xuemei Li, Limeng Chen

“…In this study, we aimed to explore the role of A1AR in the fibrosis progression of DN. Methods. We collected DN patients’ samples and established a streptozotocin-induced diabetes model in wild-type (WT) and A1AR-deficient (A1AR-/-) mice. …”
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Emerging malaria in Indonesia: An overview of Plasmodium knowlesi infections by Nisa Fauziah, Karomahul Malaya Jati, Fedri Ruluwedrata Rinawan, Naufal Fakhri Nugraha, Bachti Alisjahbana, Jontari Hutagalung

“…Individuals working outdoors were not significantly more protected compared to those working indoors (p-value of 0.116, OR = 0.15, 95 % CI: 0.02–1.49). …”
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Effects of antibiotic therapy on the early development of gut microbiota and butyrate-producers in early infants by Jun Qiu, Jun Qiu, Sha Wu, Sha Wu, Ruiwen Huang, Zhenyu Liao, Xiongfeng Pan, Kunyan Zhao, Kunyan Zhao, Yunlong Peng, Yunlong Peng, Shiting Xiang, Yunhui Cao, Yunhui Cao, Ye Ma, Zhenghui Xiao, Zhenghui Xiao

“…Furthermore, moxalactam had a more pronounced effect on the gut microbiota compared to amoxicillin-clavulanic acid.…”
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Racialized and Immigrant Status and the Pursuit of Living Donor Kidney Transplant - a Canadian Cohort Study by Eric Lui, Jasleen Gill, Marzan Hamid, Cindy Wen, Navneet Singh, Princess Okoh, Xihui Xu, Priscilla Boakye, Carl E. James, Amy D. Waterman, Beth Edwards, Istvan Mucsi

“…Introduction: Both immigrant and racialized status may be associated with the pursuit of living donor kidney transplant (LDKT). Methods: This study was a secondary analysis of a convenience cross-sectional sample of patients with kidney failure in Toronto, obtained from our “Comprehensive Psychosocial Research Data System” research database. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Work package 3: predictors Methods We followed up the QUEST cohort, a sample of 277 autistic children first assessed at age 4–9 (Wave 1) and followed up at ages 11–16 (Wave 2) and 13–18 years (Wave 3). …”
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Analog Ensemble Forecasts of Solar Wind Parameters: Quantification of the Predictability and Time‐Domain Spectral Performance by Pauline A. Simon, Christopher H. K. Chen, Mathew J. Owens, Chaitanya Sishtla

“…The AnEn predictions were found to be as accurate as persistence for short‐term forecasts and climatology for long‐term ones, and performed better than both baselines for more than 60% of the samples for a particular lead time. …”
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Polymorphisms of the <i>TPMT</i>, <i>NUDT15</i> genes and 6-mercaptopurine toxicity profile in adult patients with Ph-negative acute lymphoblastic leukemia/lymphomas on the ALL-201... by E. S. Kotova, O. A. Gavrilina, I. A. Yakutik, A. B. Sudarikov, Yu. A. Chabaeva, S. M. Kulikov, S. G. Beksaev, V. V. Troitskaya, G. A. Isinova, A. N. Sokolov, Z. T. Fidarova, I. A. Lukyanova, A. V. Abramova, V. N. Dvirnyk, I. V. Galtseva, T. N. Obukhova, E. N. Parovichnikova

“…TPMT and NUDT15 polymorphisms were detected in 11 (20 %) patients, more often in B-ALL - 7 (32 %) of 22 (p &lt;0.05). …”
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Clinical genomic profiling to identify actionable alterations for very early relapsed triple-negative breast cancer patients in the Chinese population by Liye Wang, Qinglian Zhai, Qianyi Lu, Kaping Lee, Qiufan Zheng, Ruoxi Hong, Shusen Wang

“…Comprehensive genomic profiling helps to explore the clinically relevant genomic alterations (CRGAs) and potential therapeutic targets in very-early-relapsed TNBC patients.Methods Formalin-fixed paraffin-embedded (FFPE) tumour tissue specimens from 23 patients with very-early-relapsed TNBC and 13 patients with disease-free survival (DFS) more than 36 months were tested by FoundationOne CDx (F1CDx) in 324 genes and select gene rearrangements, along with genomic signatures including microsatellite instability (MSI) and tumour mutational burden (TMB).Results In total, 137 CRGAs were detected in the 23 very-early-relapsed TNBC patients, averaging six alterations per sample. …”
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A Novel DNA Repair‐Gene Model to Predict Responses to Immunotherapy and Prognosis in Patients With EGFR‐Mutant Non‐Small Cell Lung Cancer by Fen Wang, Xue‐Wu Wei, Ming‐Yi Yang, Chang Lu, Xiao‐Rong Yang, Jia‐Yi Deng, Zhi‐Hong Chen, Qing Zhou

“…However, the role and mechanism of DDR in the genesis and progression of EGFRm NSCLC remain unclear. Methods This study included 101 EGFRm NSCLC samples from The Cancer Genome Atlas (TCGA) dataset and a GSE31210 dataset (external set) from the GEO database. …”
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Seroprevalence of Bordetella pertussis antibodies in Libyan pregnant women at the time of delivery by Suleiman Abusrewil, Mostafa Gawass, Inas Alhudiri, Marwan Sherif, Fawzi Ebrahim, Ali Amgadmi, Yosra Lamami, Salah Tabal, Musa O. Busarira, Hussain Asherkaci, Lubna Almaghur, Samira Al Dwigen, Mohamed Milad, Fatma Faraj Alhoty, Fatimah Abouthiheer, Zaynab Algharyani, Mirfat Albasheer, Hana Elghoul, Shaima Abuzaid, Khoulod Tawel, Weam Ben Hamza, Adam Elzagheid

“…Low levels of maternal antibodies make infants more susceptible to pertussis infection before they are eligible for vaccination at 2 months of age. …”
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Assessment of serological tests for antibodies to different antigens of the SARS-CoV-2 virus: comparison of six immunoassays by V. V. Belyakova, O. A. Maiorova, N, V. Ivanova, I. E. Stepanova, M. A. Smerdova, A. P. Obryadina, A. P. Toptygina

“…At the same time, 135 (81.33%) samples were positive in all kits, while 30 samples had discordant results (18.07%), and in 9 sera, specific IgG was not detected in 2 or more kits. …”
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Few-shot cow identification via meta-learning by Xingshi Xu, Yunfei Wang, Yuying Shang, Guangyuan Yang, Zhixin Hua, Zheng Wang, Huaibo Song

“…The proposed cow identification model attained an accuracy of 90.43 % with only five samples per cow for 20 cows, outperforming other state-of-the-art methods. …”
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Pre-treatment Circulating Tumor Cell Associated White Blood Cell Clusters Independently Predict Poor Survival in Patients with Extensive-disease Small Cell Lung Cancer by Ying Wang, Minghang Zhang, Cen Chen, Yanxia Liu, Yuan Gao, Hongxia Li, Baohua Lu, Mingming Hu, Hongmei Zhang, Peter Ping Lin, Zhanliang Ren, Tongmei Zhang, Shaofa Xu

“…Design: This prospective, non-interventional, single-center study included 48 patients with LD-SCLC and 47 patients with ED-SCLC. Methods: A total of 95 SCLC patients were prospectively enrolled and serial blood samples were obtained before chemotherapy administration (t 0 ) and after 2 cycles of chemotherapy (t 1 ). …”
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Hospital-related healthcare expenditure of impending versus completed pathological femur fractures: a propensity score matched study of 265 patients by Tom M de Groot, Michelle R Shimizu, David Shin, Olivier Q Groot, Stein J Janssen, Kevin A Raskin, Eric T Newman, Marco L Ferrone, Santiago A Lozano-Calderon, Joseph H Schwab, Paul C Jutte

“…Patients with completed pathologic fractures were more often discharged to rehabilitation facilities (57/100, vs 30/100, P < 0.01). …”
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A Prospective Analysis of the Burden of Multi-Drug-Resistant Pathogens in Acute Appendicitis and Their Implication for Clinical Management by Faruk Koca, Sara Fatima Faqar-Uz-Zaman, Claudia Reinheimer, Michael Hogardt, Volkhard A. J. Kempf, Paul Ziegler, Andreas A. Schnitzbauer, Armin Wiegering, Wolf Otto Bechstein, Patrizia Malkomes

“…These patients required more frequent postoperative antibiotic treatment (65.5% vs. 40.8%, <i>p</i> = 0.03) and therapy adjustments (37.9% vs. 15.8%, <i>p</i> = 0.02). …”
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