Dextrose prolotherapy at varying concentrations ameliorates tendon injury via IGF-2R: an integrated study of Mendelian randomization and an animal model by Lina Zhou, Hui Liang, Yulin Chen, Kai Hu, Xixia Liu

“…Two-sample MR analysis was performed to investigate the causal relationships between the identified targets and Achilles tendinopathy. …”
Get full text

A comprehensive systematic review of pharmacological and non-pharmacological depression interventions for patients on dialysis by Ahyeon Cho, Tammy Tran, Laura Telfer, Ahmad Matarneh, Sundus Sardar, Nasrollah Ghahramani

“…Future research should focus on multicenter trials with larger, more diversified populations and stronger study designs.…”
Get full text

A systematic review of childhood maltreatment assessments in population-representative surveys since 1990. by Wendy Hovdestad, Aimée Campeau, Dawn Potter, Lil Tonmyr

“…Fourteen surveys assessed more than three types; six of these were conducted since 2010. …”
Get full text

Regional prefrontal and hippocampal differences in gray matter volume are linked to the propensity for renewal in extinction learning by Silke Lissek, Martin Tegenthoff

“…In bilateral anterior cingulate cortex (ACC) and anterior hippocampus, GMV was overall higher in NoREN. In the complete sample, higher GMV in IFG BA 47, vmPFC BA11, bilateral ACC and bilateral anterior hippocampus was associated with less renewal, and partially with a higher error level in extinction learning in a novel context.DiscussionThe findings suggest that higher GMV in several regions active during extinction learning may support a more thorough processing of extinction trials which in turn could be conducive to an extinction recall solely based on recent extinction memory, disregarding context information. …”
Get full text

Drug Abuse Perception and Associated Variables among Secondary School Students in Duhok City by Alaa Noori Sarkees, Sardar Abdullah Issa, Azad Jameel Hussein

“…A probability sample was adapted to select students from each secondary school to reach (135) students. …”
Get full text

Assessment of biosafety training and practices in biomedical laboratories in Kinshasa, Democratic Republic of the Congo by Diane Sare Gamani, Gertrude Mongila Matimada, Lydie Hamunaki Masika, Placide Ngandu Cyanga, Tacite Kpanya Mazoba, Jérémie Masidi Muwonga

“…A convenience sample of 290 laboratory staff members was interviewed using a structured questionnaire. …”
Get full text

Oriented R-CNN With Disentangled Representations for Product Packaging Detection by Jiangyi Pan, Jianjun Yang, Yinhao Liu, Yijie Lv

“…However, despite the state-of-the-art methods being tested on public datasets, there still remains a considerable gap when applied to real-world scenarios. …”
Get full text

Effect of cementation, cement type and vent holes on fit of zirconia copings by Syed Rashid Habib, Mohsin Ali, Abdulaziz Al Hossan, Ahmad Majeed-Saidan, Mohammad Al Qahtani

“…Objectives: To investigate the effect of cementation, cement type and vent-holes on the marginal and internal fit of Zirconia (Zr) Copings. Materials and methods: Extracted premolars (N = 100) were mounted in resin and prepared for Zr crowns. …”
Get full text

The Impact of Intermediate Antidrug Antibodies to Infliximab and Adalimumab on Clinical Outcomes in Patients with Crohn’s Disease or Ulcerative Colitis by Chaoyang Wang, Mazen Tolaymat, Raymond Cross

“…Conclusion: Patients with intermediate titres were more likely to lose response to anti-TNF drugs and require a change in anti-TNF therapy than patients with low titres. …”
Get full text

Comparative effects of different loads of aerobic exercise on lipid metabolism in MASLD rats: a perspective from the gut-liver axis by Deng Dongkun, Jiang Qingfeng, Li Chang, Lin Yunhua, Shi Jiaming, Liu Yufei, Xu Lin

“…Therefore, the present study aimed to clarify the optimal exercise load for improving MASLD and to reveal its molecular mechanisms in the treatment of metabolic-associated fatty liver disease (MASLD) in the context of the enterohepatic axis.MethodsForty male rats were randomly divided into two groups: NFD (n = 8) and HFD (n = 32). …”
Get full text

Excess prevalence of chronic diseases in elderly people with diabetes and non-diabetics in Poland. by Katarzyna Więckiel-Lisowska, Agata Wojciechowska, Łukasz Wierucki, Sonia Woch, Krzysztof Flis, Adrian Lange, Marcin Rutkowski, Tomasz Zdrojewski, Piotr Bandosz

“…However, their excessive prevalence among older adults with diabetes in Poland is unknown.<h4>Methods</h4>The prevalence of chronic diseases was assessed in the nationally representative random sample of 5,987 Polish adults aged 60+ (Polsenior2 study, data collected between 2018 and 2020). …”
Get full text

Deep Circumflex Iliac Artery (DCIA) Free-Flap Mandibular Reconstruction Using Patient-Specific Surgical Guides and Customized Plates: A Preliminary Study by Hyo-Joon Kim, Ji-Su Oh, Seong-Yong Moon

“…This complication led to the modification of the plate design to include six or more holes in subsequent cases. <b>Conclusions</b>: Despite limitations including the small sample size and short follow-up period, our preliminary results demonstrate that computer-aided surgical planning with patient-specific devices can significantly improve the accuracy and predictability of DCIA flap mandibular reconstruction, even in challenging revision cases. …”
Get full text

Correlation between gene polymorphisms and perioperative analgesia in patients undergoing gynecological surgery by Meng Cai, Xiaofeng Lei, Lin Gan, Jing Li, Jin Yu

“…Preoperative pain sensitivity was evaluated using Pain Sensitivity Questionnaire and Pain Catastrophizing Scale (PCS). Venous blood samples were collected for SNP analysis of nine genes. …”
Get full text

Predicting patent challenges for small-molecule drugs: A cross-sectional study. by Ally Memedovich, Brian Steele, Taylor Orr, Shanzeh Chaudhry, Mina Tadrous, Aaron S Kesselheim, Aidan Hollis, Reed F Beall

“…Market value was the most important predictor variable, with larger markets being more likely to be associated with patent challenges. …”
Get full text

Analysing the Multidimensional Nature of Poverty: a Focus on Housing Insecurity in South Africa by Zamokuhle Ndaba, Steven Henry Dunga, Precious Mncayi-Makhanya

“…This study used primary data with a sample size of 600 South African households collected in four types of areas in two provinces (Gauteng and KwaZulu Natal). …”
Get full text

Discipline and Performance of Health Employees at UPT Puskesmas Muara Laung in 2023 by Aulia Rachman, Lucia Andi Crismilasari, Ermeisi Er Unja

“…The number of samples used was 30 UPT Muara Laung health centre employees. …”
Get full text

Unit for Splitting Degraded Mountain Meadows and Pastures Based on a Mini Tractor by S. M. Dzhibilov, L. R. Guluyeva

“…(Research purpose) To create a small-sized maneuverable splitter for mountain meadows and pastures, to determine its agrotechnical parameters, to give a graphic-analytical substantiation of the splitting working process in areas with a slope of up to 12 degrees. (Materials and methods) A technical examination of the unit laboratory sample was carried out at an altitude of 1540 meters above the sea level. …”
Get full text

Using prior information to individualize start item selection when assessing physical functioning with the EORTC CAT Core by Morten Aa. Petersen, Hugo Vachon, Johannes M. Giesinger, Mogens Groenvold, on behalf of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Group

“…We assessed the potential for using such cross-domain information to individualize start item selection for the EORTC CAT Core physical functioning. Methods The potential for predicting physical functioning (PF) scores from each of the 14 other domains using linear regression was assessed in an international, mixed sample comprising 10,084 cancer patient assessments. …”
Get full text

360 virtual reality pediatric mass casualty incident: A cross sectional observational study of triage and out‐of‐hospital intervention accuracy at a national conference by Jason Lowe, Cynthia Peng, Christopher Winstead‐Derlega, Henry Curtis

“…Most felt that 360 VR was more immersive than mannequin‐based simulation training (median = 5). …”
Get full text

A randomized controlled trial to compare the effect of oxycodone and sufentanil on postoperative analgesia and immune function for laparoscopic resection of colorectal cancer by Chunmei Lin, Zhiqiao Xu, XinLiang, Hong Wei, Xiaoping Wang

“…The visual analog scale (VAS) score and serial blood samples were assessed during perioperative period. …”
Get full text