Detection of blaTEM, blaOXA, blaCTX-M, and blaSHV genes of antibiotic resistance in diarrheagenic E. coli causing enteric infection in hypertensive patients at Laquintinie Hospital... by Ornella Djiolieu Tsobeng, Armelle T. Mbaveng, Michael F. Kengne, Ballue S.T. Dadjo, Delano G.T. Fonjou, Victor Kuete

“…This study aimed to determine the distribution of different virulence genes of E. coli isolates in hypertensive and non-hypertensive patients and their association with some selected beta-lactam resistance genes. Methods: At the Douala Laquintinie Hospital, 518 fecal samples were collected from both hypertensive and non-hypertensive patients with enteric infections. …”
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Clinical and biochemical characteristics of patients with acromegaly and normal or increased prolactin levels by Yuliya A. Kukushkina, Irena A. Ilovayskaya

“…Aim: To identify hallmarks of clinical and biochemical parameters in patients with acromegaly and normal or increased prolactin level. Methods: We performed a single center, single sample retrospective, observational cohort uncontrolled non-interventional study in 306 patients (70 men and 236 women) with acromegaly examined from July 2021 to June 2024, 50 of them with a pituitary microadenomas and 256 with macroadenomas. …”
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Predictive Modeling of Acute Respiratory Distress Syndrome Using Machine Learning: Systematic Review and Meta-Analysis by Jinxi Yang, Siyao Zeng, Shanpeng Cui, Junbo Zheng, Hongliang Wang

“…The findings will provide evidence-based insights to support the development of more accurate and effective ARDS prediction tools. …”
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A comparative analysis of the different HIV testing techniques used in Zambia: data from a clinical performance study by Loveness Mukuka, Andros Theo, Precious Simushi, Mowa Zambwe, Peter J. Chipimo

“…Hence the need to develop better first line HIV testing techniques. Method A quantitative descriptive approach was used to analyze samples of 2564 participants, between the ages of 15 to 95 years from two Lusaka sites. …”
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Effects of ketogenic diets on polycystic ovary syndrome: a systematic review and meta-analysis by Rossella Cannarella, Michele Rubulotta, Alessia Leonardi, Andrea Crafa, Antonio Calvo, Federica Barbagallo, Sandro La Vignera, Aldo E. Calogero

“…Further studies with larger sample sizes and more robust study designs are needed to confirm these findings.…”
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Effects of Plant-Origin Superoxide Dismutase Supplementation on Selected Parameters of Inflammation and White Blood Cell Count in Athletes by Olina Dudašova Petrovičova, Ivan Stanković, Brižita Đorđević, Neda Milinković, Violeta Dopsaj, Milivoj Dopsaj

“…More studies including a greater number of participants are necessary to confirm the influence of antioxidant supplementation on immunity and inflammation in athletes.…”
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Trajectories and social determinants of child cognitive development: a prospective cohort study from infancy through middle childhood in Dhaka, BangladeshResearch in context by Viviane Valdes, Eileen F. Sullivan, Fahmida Tofail, Lisa M. Thompson, Shahria H. Kakon, Talat Shama, Rashidul Haque, Charles A. Nelson

“…Higher levels of maternal education (t = 2.22, p = 0.03) and more food security (t = 4.48, p < 0.001) were protective for cognition longitudinally. …”
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Variability of the SARS-CoV-2 Virus and the Susceptibility of the Population in the Dynamics of the Development of the Epidemic Process by I. V. Feldblum, M. Yr. Devyatkov, T.ёёё M. Repin, K. A. Subbotina, N. B. Voldshmidt, T. V. Shutova

“…The formation of the epidemic variant of the pathogen (Delta genovariant) occurred within 12 weeks, it dominated for more than 6 months, increasing the incidence by 2.8 times, mortality by 17.3 times (epidemic spread phase). …”
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Fine-needle aspiration biopsy possibilities in studying the molecular genetic landscape of breast tissue by V.  V.  Rodionov, O.  V.  Burmenskaya, V.  V.  Kometova, A.  A.  Smetnik, M.  V.  Rodionova, D.  Yu.  Trofimov, L.  A.  Ashrafyan, G.  T.  Sukhikh

“…The ability to conduct molecular genetic research on small samples of breast tissue makes it possible to obtain the material using the most minimally invasive method. …”
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Nuclear IRF-1 expression as a mechanism to assess “Capability” to express PD-L1 and response to PD-1 therapy in metastatic melanoma by Mario Sznol, Harriet M. Kluger, Pok Fai Wong, James W. Smithy, David L. Rimm, Vasiliki Pelekanou, Lauren M. Moore, Jamaal Rehman, Patricia Gaule, Veronique M. Neumeister

“…Specifically, response is seen in tumors that do not express programmed death ligand 1 (PD-L1), highlighting the need for a more sensitive biomarker. We hypothesize that capacity to express PD-L1, as assessed by an assay for a PD-L1 transcription factor, interferon regulatory factor 1 (IRF-1), may better distinguish patients likely to benefit from anti-PD-1 immunotherapy.Methods Samples from 47 melanoma patients that received nivolumab, pembrolizumab, or combination ipilimumab/nivolumab at Yale New Haven Hospital from May 2013 to March 2016 were collected. …”
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Epidemiology and genetic diversity of classic human astrovirus with whole-genome sequence analysis in inpatient children under 5 years of age in Yunnan, China by Zhichao Wang, Lili Jiang, Lihua Chen, Jianping Cun, Xiaofang Zhou, Yongming Zhou, Wenpeng Gu, Yihui Cao

“…HAstV RNA was detected in 4.88% (122/2501) of the stool samples in the study. There were 1.46 times more male patients than female patients (1484/1017), and their HAstV detection rates were 4.58% (68/1484) and 5.31% (54/1017), respectively, with no statistically significant difference (χ2 = 0.688 P = 0.407). …”
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The relationship between value orientations and understanding of emotions in preschoolers by Olga V. Morozova, Ekaterina V. Kartashova, Ulyana D. Guseva, Daria A. Bukhalenkova

“…The sample included 46.7% of boys. Methods. To study the child’s value orientations, the “Three Wishes” technique (Prizhozhan, Tolstykh, 2005; Veraksa, 2012) was used. …”
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Molecular investigation of feline herpesvirus 1 (fhv-1) and feline calicivirus in cats with respiratory system problem by Seval Bilge Dağalp, Fırat Doğan, Touraj Aligholipour Farzani, Ali Rıza Babaoğlu, Gülizar Acar Kırmızı, Mehmet Çabalar

“…<p> <b>Materials and Methods:</b> For this purpose, a total of 119 specimens were collected from 70 from cats clinically showing respiratory system problem, 31 nasal, 30 conjunctival, 8 oral, 7 orafarengeal and 11 rectal swaps and 32 EDTA blood samples. …”
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Evolving superpixel-level affinity based on contrastive learning and good neighbors for hyperspectral image clustering by Yao Qin, Guisong Xia, Kun Li, Yuanxin Ye, Weiping Ni

“…Recently, graph clustering has been applied to hyperspectral image (HSI) clustering and proves to be effective on capturing the complex affinity among hyperspectral samples to a certain extent. However, graph clustering based on sample-level affinity usually suffers from a heavy computation overhead due to the generation of coefficient matrices. …”
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A retrospective analysis of 6942 amniocentesis cases by Qingsha An, Yuxiao Huang, Feifei Yu, Yilun Tao, Juan Li, Xiaoze Li

“…Regarding diagnostic approaches, 27.65% of the cases utilized a single method, 66.96% employed two methods, and 5.39% used three or more methods. …”
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Metabolic pathways mediating insulin resistance and gestational diabetes mellitus discovered by high-dimensional systematic Mendelian randomization by Wei Chen, Mingjuan Luo, Jingyi Guo, Suna Wang, Dandan Yan, Xiaohui Feng, Yunting Huang, Tao Zeng, Li Shen, Rong Zhang, Jing Yan, Cheng Hu, Weituo Zhang, Xiangtian Yu

“…Conclusions These results indicated that targeting specific metabolic pathways through dietary intervention is worth exploring as a possible GDM prevention approach, and hdsMR is more efficient in finding causal mediating metabolic pathways than traditional MR methods.…”
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Bottom Trawling and Multi‐Marker eDNA Metabarcoding Surveys Reveal Highly Diverse Vertebrate and Crustacean Communities: A Case Study in an Urbanized Subtropical Estuary by Jack Chi‐Ho Ip, Hai‐Xin Loke, Sam King Fung Yiu, Meihong Zhao, Yixuan Li, Yitao Lin, Chun‐Ming How, Jiezhang Mo, Meng Yan, Jinping Cheng, Vincent Chi‐Sing Lai, Leo Lai Chan, Kenneth Mei Yee Leung, Jian‐Wen Qiu

“…We analyzed 16 bottom trawl samples and the eDNA from 32 two‐liter water samples using primer sets specific to fishes and mammals (MiFish‐U, 12S‐V5, and Berry‐Fish) and decapod crustaceans (MiDeca). …”
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Precision computerised cognitive behavioural therapy (cCBT) intervention for adolescents with depression (SPARX-UK): protocol for the process evaluation of a pilot randomised contr... by Charlotte Lucy Hall, Chris Hollis, Kareem Khan, Peter Fonagy, Kirsty Sprange, Cathy Creswell, Yi Yang, Vibhore Prasad, Kapil Sayal, Nitish Jawahar, Ellen Townsend, Dorothee Auer, Praveetha Patalay, Aja Murray, Yvonne Kelly, Boliang Guo, Christopher R Tench, Paul Stallard, Louise Arseneault, Sieun Lee, Sally Merry, Charlotte Hall, Jo Gregory, Rory O’Connor, Emma Nielsen, Edmund Sonuga-Barke, Hannah Wright, Petr Slovak, Emily Lloyd, Josimar De Alcantara Mendes, Carolyn Ten Holter, Marina Jirotka, Aaron Kandola, Sonia Livingstone, Kasia Kostryka-Allchorne, Jake Bourgaize, Mariya Stoilova, Marianne Etherson, Chris Greenhalgh, Jim Warren, Vajisha Wanniarachchi, Kevin Glover, Mathijs Lucassen, Karolina Stasiak, Camilla Babbage, Adam Parker, Joanna Lockwood, Elvira Perez Vallejos, Rebecca Woodcock, Sarah Doherty, Lucy-Paige Willingham, Camilla May Babbage, Matthew Jeffery, Peiyao Tang, Holly Griffiths, Lily Roberts, A. Jess Williams, Lucy Hitcham

“…The findings from this process evaluation will also inform the decision about whether and how to proceed with a full randomised controlled trial, as well as the development of more effective interventions which can be personalised more precisely via varying levels of human support. …”
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Single Nucleotide Polymorphism (SNP) Assays for Disaster Victim Identification (DVI) by Sahar M. Ibrahim, Arwa M. Salih, Dina Hameed Haider, sabaa Raad Jaafar, Marwa Adel Hussein, Nada Hassan Bedair, Ruaa Hussein Ali, Ruaa Maan Attallah, Omar A Mahmoud, Farah B. Abd, Shahrazad H. Muhi

“…SNPs are highly valuable genetic markers for DVI, particularly because they are insensitive to DNA degradation and possess high annotation potential, making their underlying biological information invaluable for human identification in molecular forensics. Unlike traditional methods, SNP typing offers a more powerful set of genetic markers, enabling complex analysis and profiling techniques suitable for various genotyping scenarios, from specialized forensic markers to expanded tiling arrays. …”
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RISK FACTORS ASSOCIATED WITH THE BIRTH OF CHILDREN WITH A BODY WEIGHT LESS THAN 2500 G: RESULTS OF A RETROSPECTIVE COHORT MULTICENTER STUDY by I. A. Deev, K. V. Kulikova, O. S. Kobyakova, E. S. Kulikov, A. V. Holopov, N. A. Stepanov, I. N. Antonova, E. G. Bybchenko, K. E. Holtzman, E. N. Dorovskaya, E. N. Kozhevnikova, L. V. Ledyaykina, N. A. Makarova, M. A. Permjakova, N. G. Popova, A. A. Stradina, L. A. Fedorova, A. Fomenko, E. S. Kharitonova, E. B. hodosevich, I. N. Chugainova

“…Background. Improving nursing methods of newborns with birth weight less than 2500 g resulted in an increase in the proportion of children at risk for the development of severe disabling conditions. …”
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