Quantifying the tumour vasculature environment from CD-31 immunohistochemistry images of breast cancer using deep learning based semantic segmentation by Tristan Whitmarsh, Wei Cope, Julia Carmona-Bozo, Roido Manavaki, Stephen-John Sammut, Ramona Woitek, Elena Provenzano, Emma L. Brown, Sarah E. Bohndiek, Ferdia A. Gallagher, Carlos Caldas, Fiona J. Gilbert, Florian Markowetz

“…We also performed a 3D histology analysis on a separate tumour sample as a proof of principle, providing a more comprehensive visualization of vasculature morphology compared to the standard 2D cross-section of a tissue sample. …”
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Hydrocarbon Generation Characteristics and Geological Significance of Deep Organic‐Rich Shales in the Gulong Fault Depression, Songliao Basin, Northeastern China by Bo Hu, Xiaomei Li, Jiajun Liu, Zhuang Cai, Hongyan Liu, Yan Xu, Fangwen Chen

“…Thermal simulation experiments on moderately mature source rock samples were conducted to assess the hydrocarbon conversion rates, hydrocarbon generation potential, and hydrocarbon generation phases using chemical kinetic methods. …”
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Genetic features of tourmaline from the magnesian skarns of Kuhilal deposit, Southwestern Pamir by A. K. Litvinenko, E. I. Romanova, O. A. Yakushina

“…The samples were examined by mineralogical and petrographic methods, X-ray diffraction analysis using a DRONE-3M (analyst A.V. …”
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CO22 | Assessment of coagulation profiles in septic patients using viscoelastic coagulation monitoring and rotational thromboelastometry in an internal medicine setting

“…The identification of a lower MCF cut-off versus the prior 44 mm upper normal limit set by the manufacturer, improves the test’s sensitivity and specificity, allowing for earlier and more accurate detection of hypercoagulable states. …”
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Study on the Combustion Behavior and Kinetic Characteristics of Semi-Coke from Oil Shale by Fajun Zhao, Lei Zhang, Sen Liu, Tianyu Wang, Peiyong Xue, Mingxuan Wu, Jiankang Yun

“…Kinetic parameters calculated using the model-free methods (OFW and KAS) and the model-based Coats–Redfern method reveal that the activation energy gradually increases with the conversion rate, indicating a multi-step reaction characteristic of the combustion process. …”
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The Application of Machine Learning Algorithms to Predict HIV Testing in Repeated Adult Population–Based Surveys in South Africa: Protocol for a Multiwave Cross-Sectional Analysis... by Musa Jaiteh, Edith Phalane, Yegnanew A Shiferaw, Refilwe Nancy Phaswana-Mafuya

“…ConclusionsThis study will contribute to existing knowledge and deepen understanding of factors linked to HIV testing beyond traditional methods. Consequently, the findings would inform evidence-based policy recommendations that can guide policy makers to formulate more effective and targeted public health approaches toward strengthening HIV testing. …”
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Aspects of Stage-by-Stage Diagnosis of Pulmonary Mycobacteriosis in Real Clinical Practice by N. L. Karpina, A. D. Egorova, Ya. O. Chesalina, I. Yu. Shabalina, A. E. Ergeshov

“…During X-ray examination, the bronchiectatic form – 52.1% (74/142) was detected more often compared to the abdominal – 30.9% (44/142) and focal forms – 16.9% (24/142) (p<0.001). …”
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Manifestation of a complex of Fusarium solani (Mart.) Sacc. species on seeds and seedlings of cereals, legumes, oilseeds and cereals by T. Rozhkova, L. Biliavska, H. Iutynska, L. Tytova, N. Leonova, M. Loboda, A. Sylchuk, Ye. Rozhkova

“…To establish the peculiarities of infection of seeds and seedlings of cereals, legumes, oilseeds and cereals by a complex of FSSC species, to determine the factors influencing the spread of the pathogen. Methods. Laboratory methods: germination of crop seeds in different soil samples and study of seedling development; identification of fungal species that formed mycelium layers during seed germination; analysis of soil mycobiota; determination of drug efficacy. …”
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Burnout and its Factors in Healthcare Workers Involved in Providing Health Care for Patients With COVID-19 at Different Stages of the Pandemic by A. B. Kholmogorova, S. S. Petrikov, A. Y. Suroyegina, O. Y. Mikita, A. A. Rakhmanina, A. P. Roy

“…To compare them with the indicators of a mixed sample of medical workers from different institutions and regions surveyed in the first months of the pandemic (March–April), and also to highlight the main factors of distress and protective factors.Material and methods. …”
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Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation by Yimin Zhou, Xin Li, Zixiu Wang, Liqi Ng, Rong He, Chaozong Liu, Gang Liu, Xiao Fan, Xiaohong Mu, Yu Zhou, Yu Zhou

“…However, this study has some limitations, such as unidentified SRGs, a small sample size. Future research requires more in vitro and in vivo experiments to deeply explore regulatory mechanisms and develop intervention methods.…”
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Lung Health of Early COPD (LHEC): A Multi-Center Cohort Study—Rational and Design by Li W, Lei J, Li B, Tang X, Peng Y, Huang K, Yang T

“…Comprehensive and follow-up questionnaires will be administered, and the participants will undergo physical examination, pulmonary function testing, high-resolution computed tomography (CT), routine blood tests, and biological sample collection. We will analyze the changes in lung function, CT images, symptoms, biomarkers, and other relevant parameters across the different groups.Discussion: There is an urgent need for a more precise definition of early COPD for intervention at an earlier stage. …”
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Retrospective analysis of children with 46,XX testicular/ovotesticular DSD: a 10-year single-center experience by Yan Gong, Xiaoqin Yin, Jing Xu, Yan Li, Qingxu Liu, Shasha Zhou, Fei Wang, Yiqing Lyu, Sheng Guo, Wenyan Huang, Pin Li

“…This study aimed to summarize the clinical characteristics and outcomes of 46,XX TDSD/OTDSD in childhood.MethodsThe sexual development characteristics, hormone profiles, chromosomal analysis, fluorescence in situ hybridization analysis (FISH) sex-determining region Y (SRY) analysis (peripheral blood and tissues), molecular genetic etiology, gonadal pathology, risk of gonadal tumors, and assigned gender of 52 patients were collected and analyzed.ResultsThe median age at initial presentation was 18 months, and external masculinization score(EMS) within the range of 3 < EMS ≤ 6 was more prevalent. …”
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Properties and sensory acceptability of creatine-fortified foods using ultra-micronized creatine monohydrate – the KREAFOOD Project by Julián Quintero-Quiroz, Sebastian Botero-Ramirez, Simon Jaramillo-Caro, Natalia Zuluaga, Diego A. Bonilla

“…Additionally, rheological analysis was conducted for the mocaccino, while texture profile analysis (TPA) was used to assess the pancakes.Results Creavitalis® was characterized by its smaller particle size and thermal stability, which facilitates more homogeneous dispersion and enhanced sensory texture in fortified food applications. …”
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Identification and Analysis of Effective Factors on the Trend of the Iranian Banking Network to Implement Green Banking by W. Qelich

“…The statistical population of this research was all managers and banking experts in Tehran. In the Delphi method, a standard statistical sample typically ranges from 10 to 30 questionnaires, with 28 initially considered for this research. …”
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HLA-DRB1 and DQB1 Allelic Polymorphism and Multiple Sclerosis in a Moroccan Population by Abir Fguirouche, Yahya Naji, Morad Guennouni, Raja Hazime, Safa Zahlane, Mohamed Chraa, Najib Kissani, Nissrine Louhab, Brahim Admou

“…Similarly, the DRB1*07:01–DQB*02:01 combination was rather more frequent in controls (12%, <i>p</i> = 0.01). …”
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Protein dysregulation during Leishmania infantum infection in anti-TNF immunosuppressed mice revealed through quantitative proteomics analysis of extracellular vesicles by Lorena Bernardo, Lorena Bernardo, Ana Montero-Calle, Jose Carlos Solana, Jose Carlos Solana, Marina Lozano-Rendal, Ana Torres, Ana Torres, Carmen Sánchez, Rodrigo Barderas, Rodrigo Barderas, Javier Moreno, Javier Moreno, Eugenia Carrillo, Eugenia Carrillo

“…In this model, we compared anti-TNF immunosuppression with no immunosuppression before and after VL treatment with Sb.MethodsSerum-derived extracellular vesicles (EVs) were analyzed through label-free quantitative proteomics to identify proteins involved in both VL severity and the impact of anti-TNF immunosuppression on treatment outcome.ResultsIn total, 223 dysregulated proteins were found in the pre-treatment groups, the majority of which, such as vitronectin, haemopexin or caveolin-1, were downregulated in the anti-TNF samples. …”
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Design and Baseline Evaluation of Social Media Vaping Prevention Trial: Randomized Controlled Trial Study by William Douglas Evans, Megumi Ichimiya, Jeffrey B Bingenheimer, Jennifer Cantrell, Alexander P D'Esterre, Olivia Pincus, Linda Q Yu, Elizabeth C Hair

“…Just less than 45% of participants were non-Hispanic White (n=3728, 44.7%), just less than 47% (n=3913, 46.9%) of the sample was male, more than 44% (n=3704, 44.4%) reported completing high school, and 79.3% reported meeting basic needs or better. …”
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Application of additive manufacturing for the adaptive design of ultrasound phantoms by Lukas Zalka, Lukas Zalka, Johannes Köhrer, Johannes Köhrer, Chatsuda Songsaeng, Chatsuda Songsaeng, Peter Homolka, Christian Kollmann, Johann Hummel, Johann Hummel, Michael Figl, Michael Figl

“…These advanced imaging and reconstruction procedures require more complicated phantom designs that contain different materials with precisely designable acoustic properties for validation and quality assurance (QA).MethodsTo fabricate such phantoms, we produced molds for casting ultrasound phantoms using additive manufacturing. …”
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Unravelling the role of secretory Immnuoglobulin-A in COVID-19: a multicentre study in nursing homes during the first wave by Rafael Bielza, Patricia Pérez, Nuria García, Laura Ballesteros-Sanabria, Rosa María Martínez, Azam Ghazi, Clara Hernando, María Victoria Rodríguez, Israel J. Thuissard, Cristina Andreu-Vázquez, José Manuel Bautista

“…“Induced” SIgA-S1 patients were more likely to be symptomatic (60.3% vs. 29%; p < 0.001) and exhibited upper respiratory tract symptoms more frequently (25.1% vs. 6.5%; p = 0.020) compared to “non-induced” patients. …”
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Pulmonary Vascular Thrombosis in COVID-19: Clinical and Morphological Parallels by O. Ya. Porembskaya, V. N. Kravchuk, M. I. Galchenko, R. V. Deev, M. Sh. Chesnokov, A. V. Avanesyan, K. V. Lobastov, S. N. Tsaplin, L. A. Laberko, V. S. Ermakov, O. V. Pashovkina, I. V. Schastlivtsev, S. A. Sayganov

“…We aimed to study the histological and thrombotic changes in lung vessels in patients who died with COVID-19, to access the correlation between anticoagulation therapy (ACT) and thrombotic events (TE), treatment results, clinical and laboratory patients' characteristics.Material and Methods. We retrospectively analyzed treatment results of patients hospitalized with COVID-19 and lung vessel samples of the deceased patients. …”
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