Probing the limits of cis-acting gene regulation using a model of allelic imbalance quantitative trait loci. by Cathal Seoighe, Seán Connaire, Mehak Chopra

“…Imbalance in gene expression between alleles is a hallmark of cis-acting expression quantitative trait loci (eQTLs) and several methods have been developed to exploit allelic imbalance to support the identification of eQTLs. …”
Get full text

Family correlates of behavioral problems among adolescents in Rwanda. by Eugene Harerimana, Jean d'Amour Muziki, Eric Nshimyumuremyi, Thaoussi Uwera, Augustin Nshimiyimana, Jean Mutabaruka

“…<h4>Results</h4>Females exhibited more behavioral problems than males. Child and adolescent trauma (β = 0.705, t = 8.21, p < .001) and neglect (β = 0.147 t = 2.15, p < .05) were two significant family correlates in our sample. …”
Get full text

Microbiological and Nutritional Analyses of Soybean Cake (Awara) and Camel Milk Cheese (Chukwui) Local Snacks, Vended in Kano Metropolis- Nigeria by Idris, A., Dabo, N.T. P.

“…Selective media were used to isolate some specific pathogens, and antibiotic sensitivity profiles of the isolates were determined using the disc-diffusion method. Proximate analyses were also carried out on 50 representative samples using the Official Methods of Analysis of the AOAC. …”
Get full text

Replay-Based Incremental Learning Framework for Gesture Recognition Overcoming the Time-Varying Characteristics of sEMG Signals by Xingguo Zhang, Tengfei Li, Maoxun Sun, Lei Zhang, Cheng Zhang, Yue Zhang

“…The density-based spatial clustering of applications with noise (DBSCAN) algorithm is utilized to select representative samples to update the replayed dataset, achieving a 93.7% recognition rate with fewer samples, which is better than the other three conventional sample selection methods. …”
Get full text

Mechanical characterization of human brain tumors from patients and comparison to potential surgical phantoms. by Daniel C Stewart, Andrés Rubiano, Kyle Dyson, Chelsey S Simmons

“…Since characterization methods vary widely for soft biological and synthetic materials, here, we have developed a characterization method compatible with abnormally shaped human brain tumors, mouse tumors, animal tissue and common hydrogels, which enables direct comparison among samples. …”
Get full text

A single-centre, randomised trial to compare diagnostic yield and safety between endobronchial cryobiopsy and endobronchial forceps biopsy procedure in patients with endobronchial... by Swapnendu Misra, Ankan Bandyopadhyay, Anupam Patra, Ritabrata Mitra, Amitava Sengupta, Somenath Kundu

“…Conclusions: Cryobiopsies were more successful than forceps biopsies particularly for diagnosis of infiltrative growth. …”
Get full text

Screening and genotyping of group B streptococcus in pregnant and non-pregnant women in Turkey by Feyza Alp, Duygu Findik, Hatice Turk Dagi, Ugur Arslan, Aybike Tazegul Pekin, Setenay Arzu Yilmaz

“…GBS was isolated from 65 (13%) samples. GBS was positive in 70 (14%) samples by antigen test and in 62 (12.4%) by PCR. …”
Get full text

Microbial and clinical disparities in pneumonia: insights from metagenomic next-generation sequencing in patients with community-acquired and severe pneumonia by Wang Luo, Shuhua Zhang, Jinhuan Sun, Jinhuan Sun, Jianhui Xu, Weihua Huang, Ruiqing Hao, Zhao Ou, Zhao Ou, Ziyang Wen, Ziyang Wen, Daiwei Wang, Daiwei Wang, Guanhua Xiao, Hangming Dong

“…Severe pneumonia (SP), a more critical form of CAP, has higher mortality and often requires intensive care. …”
Get full text

Proteomic profiling of human plasma and intervertebral disc tissue reveals matrisomal, but not plasma, biomarkers of disc degeneration by Christabel Thembela Dube, Hamish T. J. Gilbert, Niamh Rabbitte, Pauline Baird, Sonal Patel, Jeremy A. Herrera, Ivona Baricevic-Jones, Richard D. Unwin, Danny Chan, Kanna Gnanalingham, Judith A. Hoyland, Stephen M. Richardson

“…Improved techniques, such as a combination of tissue and blood biomarkers, are needed to monitor the progression of IVD degeneration for more effective treatment plans. Methods To identify tissue and blood biomarkers associated with degeneration progression, we histologically graded 35 adult human degenerate IVD tissues and matched plasma from the individuals into two groups: mild degenerate and severe degenerate. …”
Get full text

Comparison of myopia-related behaviors among Chinese school-aged children and associations with parental awareness of myopia control: a population-based, cross-sectional study by Chaoying Ye, Chaoying Ye, Chaoying Ye, Yujie Wang, Yujia Liu, Yujia Liu, Yujia Liu, Xingxue Zhu, Xingxue Zhu, Xingxue Zhu, Jianmin Shang, Jianmin Shang, Jianmin Shang, Xiaomei Qu, Xiaomei Qu, Xiaomei Qu

“…Children in third-tier cities were more likely to have poor sitting position (p &lt; 0.01), a non-open view in front of a desk at home (p = 0.02), and more near activities during break times (p = 0.04). …”
Get full text

A Generative Adversarial Network-Based Extractive Text Summarization Using Transductive and Reinforcement Learning by Jing Yang, Haoshen Qin, Yiping Sun, Hao Wang, Abdullah Ayub Khan, Lip Yee Por, Roohallah Alizadehsani, Pawel Plawiak

“…We implement a Reinforcement Learning (RL)-based strategy to address an imbalance caused by more fake than real samples in the discriminator. …”
Get full text

Life course socioeconomic position, alcohol drinking patterns in midlife, and cardiovascular mortality: Analysis of Norwegian population-based health surveys. by Eirik Degerud, Inger Ariansen, Eivind Ystrom, Sidsel Graff-Iversen, Gudrun Høiseth, Jørg Mørland, George Davey Smith, Øyvind Næss

“…<h4>Background</h4>Socioeconomically disadvantaged groups tend to experience more harm from the same level of exposure to alcohol as advantaged groups. …”
Get full text

Clinical and Behavioral Correlates of Blood Acylcarnitine Profiles in Children with Autism Spectrum Disorder: A Cross-Sectional Analysis by Adriana Prato, Martina Randazzo, Maria Anna Messina, Giovanni Puglisi, Laura Rosy Aleo, Fiorella Ciantia, Lara Cirnigliaro, Renata Rizzo, Rita Barone

“…The post hoc Dunn’s test with Bonferroni correction showed that ADOS-CSS RRB was significantly higher in ASD group A compared to ASD group B (<i>p</i> = 0.013). AC C14 was more frequently decreased (<10th pc) in patients with more severe symptoms (<i>p</i> = 0.006); C10:1 tended to be more frequently increased (>90th pc) in patients with lower clinical severity (<i>p</i> = 0.052). …”
Get full text

Digitally Enabled AI-Interpreted Salivary Ferning–Based Ovulation Prediction: Feasibility Study by Elizabeth Peebles, William Finlay, Thao-Mi Nguyen, Samuel Barrett, Prudhvi Thirumalaraju, Manoj Kumar Kanakasabapathy, Hemanth Kandula, Carrie Sarcione, Kaitlyn E James, Hadi Shafiee, Shruthi Mahalingaiah

“…Participation entailed remotely collecting and uploading daily data (saliva, LH values), attending lab visits, and returning biological saliva samples. ResultsOf the 133 females recruited from February to October 2023 via targeted patient messages and a public research website, 69 (51.9%) were eligible (age 19-35 years at enrollment, currently menstruating, able to read and comprehend English, weigh more than 110 lb, have an active primary care or gynecological provider, and able to commute to the Massachusetts General Hospital (MGH) main campus within 10 days of their ovulatory event). …”
Get full text

Chronic pain, depression and cardiovascular disease linked through a shared genetic predisposition: Analysis of a family-based cohort and twin study. by Oliver van Hecke, Lynne J Hocking, Nicola Torrance, Archie Campbell, Sandosh Padmanabhan, David J Porteous, Andrew M McIntosh, Andrea V Burri, Haruka Tanaka, Frances M K Williams, Blair H Smith

“…<h4>Background</h4>Depression and chronic pain are the two most important causes of disability (Global Burden of Disease Study 2013). They occur together more frequently than expected and both conditions have been shown to be co-morbid with cardiovascular disease. …”
Get full text

Importance of attributes and willingness to pay for oral anticoagulant therapy in patients with atrial fibrillation in China: A discrete choice experiment. by Jiaxi Zhao, Hao Wang, Xue Li, Yang Hu, Vincent K C Yan, Carlos K H Wong, Yutao Guo, Marco K H Cheung, Gregory Y H Lip, Chung-Wah Siu, Hung-Fat Tse, Esther W Chan

“…Patients with lower educational attainment or income levels and less experience of bleeding or stroke had more reservations about paying for oral anticoagulant therapies with superior efficacy, safety, and convenience of use.…”
Get full text

Transformative agency of students as a resource to form civic consciousness in education system by M. V. Pevnaya, A. N. Tarasova, D. F. Telepaeva, D. S. Protasov

“…The authors analysed the data of a mass survey of young people in the Sverdlovsk region from 14 to 24 years old from 79 settlements of the region, carried out by the questionnaire method. 996 people were interviewed, the sample is representative, the error is no more than 3,5%. …”
Get full text

Práticas de gestão no desenvolvimento de produtos em empresas de autopeças Management practices in product development in autoparts industry by José Carlos de Toledo, Sérgio Luis da Silva, Dário Henrique Alliprandini, Manoel Fernando Martins, Fernanda Menezes Ferrari

“…Some of the main findings on the practices are: widespread dissemination and use of reference models for PDP partially implemented; methods and techniques for PDP Management are applied with weak inter functional integration; development team carries out the PDP activities; functional structure is still widely used; the follow-source projects are the most common type, while platform projects were also identified (average of 25% of carry out projects); and the first tier suppliers are the ones that more use practices of international pattern of PDP management. …”
Get full text

Determinants of communication between partners about STD symptoms: implications for partner referral in South Africa by A. Meyer-Weitz, P. Reddy, B. van den Borne, G. Kok, J. Pietersen

“…In this study, “talking with a partner about STD symptoms” before seeking medical treatment was viewed as an indication of the likelihood of future partner referral behaviour. Methods: A randomly selected sample of 1 477 patients with STD symptoms was interviewed using a structured questionnaire. …”
Get full text

Evaluating Food Intake of Post-Acute Myocardial Infarction Patients According to a European Guideline and Mediterranean Diet Score: DICA-NUTS Substudy by Rodrigo Damasceno de Oliveira, Lívia Costa de Oliveira, Marcio Santos Prazeres, Tais Saint Martin Fonseca, Aline Marcadenti, Angela Cristine Bersch-Ferreira, Rachel Helena Vieira Machado, Elisa Maia dos Santos, Annie Seixas Bello Moreira, Grazielle Vilas Bôas Huguenin

“…According to the 2021 ESC guidelines, the fiber intake was low with more than 79% of the sample consuming less than 30 g per day. …”
Get full text