Computational molecular insights into ibrutinib as a potent inhibitor of HER2-L755S mutant in breast cancer: gene expression studies, virtual screening, docking, and molecular dyna... by Tamizhini Loganathan, C. George Priya Doss

“…BackgroundThe proposed study integrates several advanced computational techniques to unravel the molecular mechanisms underlying breast cancer progression and drug resistance.MethodsWe investigated HER2-L755S mutation through a multi-step approach, including gene expression analysis, molecular docking, and molecular dynamics simulations.Results and DiscussionBy conducting a network-based analysis of gene expression data from breast cancer samples, key hub genes such as MYC, EGFR, CDKN2A, ERBB2, CDK1, E2F1, TOP2A, MDM2, TGFB1, and FOXM1 were identified, all of which are critical in tumor growth and metastasis. …”
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Age at entry into the Dutch child protection system of children of parents with intellectual disability: A case-control study by Lianne Bakkum, Carlo Schuengel

“…Methods: Linear and logistic regression models were used. …”
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The acquisition of foreign language vocabulary: Does spacing effect matter? by F. M. Al-Khasawneh

“…The present study aimed to examine the effect of spaced instruction on vocabulary learning and retention among Saudi EFL learners.Methodology and research methods. The sample of this study includes 30 English major students at King Khalid University. …”
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Association Study of rs1421085 and rs9939609 in FTO Gene with Gestational Diabetes in the Arak City by Parnian Hekmatpou, Maryam Maryam Ghanbari, Milad Gholami

“…Conclusions: Considering the conflicting results between the association of FTO gene polymorphisms with gestational diabetes, to better identify and understand the pathogenesis of the disease, more studies with a higher number of samples and more racial groups are needed. …”
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The correlation between positive rate of antibody or DNA and children’s age with suspected Mycoplasma pneumoniae infection by Weiguo Feng, Ying Lin, Qiang Wang, Xiaoqin Qian

“…Conclusion These results suggest that MP DNA detection identifies the MP infection earlier and more accurately than antibody detection and that younger children are more susceptible to MP infection than older children. …”
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Parental Health Literacy, Empowerment, and Advocacy for Food Allergy Safety in Schools: A Cross-Sectional Study by Laura W. Koo, Cynthia Baur, Alice M. Horowitz, Min Qi Wang

“…Methods: A sample of parents of elementary school-aged children was recruited through 26 food allergy organizations and a research patient registry. …”
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The Impact of Socioeconomic Determinants on the Quality of Life of Moroccan Breast Cancer Survivors Diagnosed Two Years Earlier at the National Institute of Oncology in Rabat by Rachid Ismaili, Leila Loukili, Hind Mimouni, Imane EL Haouachim, Abderraouf Hilali, Bouchra Haddou Rahou, Rachid Bekkali, Ahmed Nejmeddine

“…The sample size was 304 women. Data were collected using the EORTC QLQ-C30 and EORTC QLQ-BR 23 questionnaires in the Moroccan dialect. …”
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Prevalence of Amblyopia in Hawler Eye Teaching Hospital by Lamyaa Jasim Abbas, Ahmed Ismail Abdulgani, Goran Mohammed Abdulla

“…Males were more affected by amblyopia with (60.53%) while females affected with amblyopia were (39.5%) with no statistically significant difference in gender with amblyopia (P 0.916).The age more frequently had amblyopia was seven and eight (18.4%), (18.4%) respectively, the different age groups had no statistically significant difference in amblyopic patients (P 0.377). …”
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Age-related characteristics in differentiated thyroid cancer: a 20-year single-center retrospective analysis in pediatric and adolescent patients by Laura Leite-Almeida, Rita Santos Silva, Margarida Vicente-Ferreira, Carla Costa, Norberto Estevinho, Cíntia Castro-Correia, Sofia Ferreira, Maria Bom-Sucesso

“…Results: The mean age at diagnosis of the sample was 14.5 years, with a preponderance of female patients. …”
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Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies by Muhammad Faruk Bashir, Hassan Abdullahi Elechi, Mohammed Garba Ashir, Adamu Ibrahim Rabasa, David Nadeba Bukbuk, Ahmadu Baba Usman, Modu Gofama Mustapha, Mohammad Arab Alhaji

“…We studied the effect of maternal HIV infection on serum levels and transplacental transfer of anti-tetanus antibodies. Methods. A total of 162 mother-baby paired serum samples were taken and analysed for anti-tetanus antibody levels using ELISA. …”
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Comparison of Ultrasound-guided Intra-articular Injection of Platelet-rich Plasma and Triamcinolone Acetonide in the Reduction of Pain and Functional Improvement in Primary Temporo... by Shruti Pandey, Longjam Nilachandra Singh, Akoijam Joy Singh, Monica Moirangthem, S. U. Priyanka

“…Treatment options include non-invasive therapies and more invasive interventions, such as intra-articular (I/A) injections of corticosteroid and platelet-rich plasma (PRP). …”
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Gender and sex differences in adherence to a Mediterranean diet and associated factors during the COVID-19 pandemic: a systematic review by Gerrit Brandt, Marie Pahlenkemper, Cristina Ballero Reque, Luisa Sabel, Christopher Zaiser, Nora M. Laskowski, Georgios Paslakis

“…During the pandemic, an overall shift towards consuming more highly processed foods has been observed.MethodsThis systematic review investigated adherence to MD during the COVID-19 pandemic, focusing on gender differences and factors influencing adherence to MD in the general public. …”
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A Comparative Study to Assess the Level of Stress and Coping Strategies among Introvert and Extrovert Nursing Students in Selected Colleges of Nursing, Delhi and NCR by Shilpa Sharma, M. Jibanlata Devi, Arshi Anjum Khan

“…Hence, stress level was more among introvert Nursing students and coping strategies were more adopted by extrovert Nursing students. …”
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Evaluation of the safety and the reliability of day case mini-PCNL in treatment of renal stones 1 to 2 cm by D. Mostafa, T. M. El-zayat, M. A. Omer, M. S. Salem

“…Mini-PCNL has been employed more and more in the treatment on renal stones with favourable results in terms on stone clearance and low morbidities.Aim. …”
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The Use of Ibuprofen Arginate in Pain Management Following Third Molar Surgery—A Scoping Review by Claudia Lorenzi, Ilaria Cammarota, Vincenzo Mazzetti, Claudio Arcuri, Paolo Carosi, Alberto Maria Pujia

“…Results: Four studies, with a combined sample of 1245 patients, met the inclusion criteria. …”
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New Possibilities for Evaluating Markers of Alzheimer's Disease in Blood Serum by S. V. Vorobev, A. Yu. Plekhanov, I. K. Ternovykh, A. S. Usikov, A. А. Lebedev, A. N. Smirnov, N. M. Shmidt, M. S. Dunaevskiy, S. P. Lebedev

“…Given the steady increase in the number of cases of Alzheimer's disease, the issue of improving the level of its diagnosis is becoming more urgent.   The aim of the study was to develop a new method for verifying markers of Alzheimer's disease in blood serum based on graphene sensors.   …”
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Japanese Encephalitis Vaccine Generates Cross-Reactive Memory T Cell Responses to Zika Virus in Humans by Ran Wang, Meng Zhang, Linlin Zhang, Mengjia Liu, Chao Shan, Jing An, Zhengde Xie

“…However, the role of T cell immune, especially memory T cell subsets, in cross-reactive immune responses between JE vaccine and ZIKV in humans has not been reported. Methods. We examined central and effector memory CD4+ and CD8+ T cell (TCM and TEM) responses (including degranulation, cytokines, and chemokines) in the presence of JEV and ZIKV, respectively, by using qualified peripheral blood mononuclear cell samples from 18 children who had recently received a two-dose course of JE vaccine SA14-14-2 as well as seven children without JE vaccination. …”
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The mother’s level of education and attitude towers the provision of complete basic immunization in infants by Risna Ayu Rahmadani, Yuliati Lumintang, Ike FA Chabibah

“…The purpose of this research was to find out the relationship between the mother’s level of education and attitude towards the provision of complete basic immunization in infants at the Tombatu Community Health Center, Winorangian Satu Village. Methods: Partial analytical observational research with a cross-sectional design with independent variables and dependent variables conducted once at the same time with a sample size of 35 respondents. …”
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Predicting Engagement With Conversational Agents in Mental Health Therapy by Examining the Role of Epistemic Trust, Personality, and Fear of Intimacy: Cross-Sectional Web-Based Sur... by Fanny Guglielmucci, Daniela Di Basilio

“…The relative homogeneity of the sample considered—particularly in terms of age, education level, and cultural exposure—limits the generalizability of these findings to broader or more diverse populations. …”
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Do female and male patients with cervical dystonia respond differently to long-term botulinum neurotoxin therapy? by Harald Hefter, Sara Samadzadeh, Sara Samadzadeh, Sara Samadzadeh, Sara Samadzadeh, Marek Moll

“…BackgroundIdiopathic cervical dystonia (CD) affects more female than male patients. This sex-based influence on the clinical manifestation of CD may also affect outcomes after long-term BoNT therapy.MethodsTo analyze the potential differential influence of sex on the efficacy of BoNT therapy, a cross-sectional study was conducted with 135 female and 85 male patients with idiopathic cervical dystonia. …”
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