Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study by Dehao Chen, Dehao Chen, Sarah Lindley McKune, Sarah Lindley McKune, Yang Yang, Ibsa Aliyi Usmane, Ibsa Abdusemed Ahmed, Jafer Kedir Amin, Abdulmuen Mohammed Ibrahim, Abadir Jemal Seran, Nurmohammad Shaik, Amanda Ojeda, Bahar Mummed Hassen, Loic Deblais, Belisa Usmael Ahmedo, Kedir Abdi Hassen, Mussie Bhrane, Xiaolong Li, Nitya Singh, Kedir Teji Roba, Nigel P. French, Gireesh Rajashekara, Mark J. Manary, Jemal Yusuf Hassen, Arie Hendrik Havelaar, on behalf of the CAGED Research Team

“…We measured anthropometry, surveyed sociodemographic determinants, and collected stool and urine samples. A short survey was conducted during monthly visits, infant stool samples were collected, and Campylobacter spp. was quantified using genus-specific qPCR. …”
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Assessment of <i>ERBB2</i> and HER2 expression in metastatic breast cancer using the nCounter® system and a 100-gene scale by R.  M.  Paltuev, O.  A.  Volynshchikova, Sh.  R.  Abdullaeva, S.  N.  Aleksakhina, A.  S.  Artemyeva, E.  A.  Baychorov, S.  Yu.  Bakharev, Yu.  A.  Belaya, A.  A.  Bozhok, V.  A.  Vasin, V.  I.  Vladimirov, A.  Yu.  Vorontsov, E.  A.  Gaysina, A.  A.  Gofman, V.  N.  Dmitriev, E.  N.  Imyanitov, V.  V.  Klimenko, A.  V.  Komyakhov, M.  M.  Konstantinova, M. V.  Kopp, A.  G.  Kudaybergenova, I.  A.  Lalak, D.  L.  Matevosyan, N.  M.  Mudzhiri, O.  V.  Poltareva, O.  I.  Sevryukova, V.  F.  Semiglazov, T.  Yu.  Semiglazova, M.  M.  Urezkova, A.  S.  Chichkanova, L.  A.  Churilova, M.  V.  Shomova

“…To increase the efficacy of systemic therapy for breast cancer, reduce inappropriate prescribing, and ensure a tailored approach to systemic breast cancer therapy using the information on individual molecular characteristics of the tumor.Materials and methods. We explored the expression of 100 genes involved in breast cancer development in 106 tumor samples from patients with metastatic breast cancer. …”
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“Hang Ups, Let Downs, Bad Breaks, Setbacks”: Impact of Structural Socioeconomic Racism and Resilience on Cognitive Change Over Time for Persons Racialized as Black by Paris B. Adkins-Jackson, Boeun Kim, César Higgins Tejera, Tiffany N. Ford, Ariana N. Gobaud, Kyler J. Sherman-Wilkins, Indira C. Turney, Justina F. Avila-Rieger, Kendra D. Sims, Safiyyah M. Okoye, Daniel W. Belsky, Tanisha G. Hill-Jarrett, Laura Samuel, Gabriella Solomon, Jack H. Cleeve, Gilbert Gee, Roland J. Thorpe, Deidra C. Crews, Rachel R. Hardeman, Zinzi D. Bailey, Sarah L. Szanton, Jennifer J. Manly

“…Robust dementia literature suggests socioeconomic factors may also be key resiliencies. Methods: We linked state-level data reflecting the racialized landscape of economic opportunity across the 20th Century from the U.S. …”
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Participant Perceptions of Increasing Water Intake in Polycystic Kidney Disease by Sneha Amin, Irene Sangadi, Margaret Allman-Farinelli, Neil Boudville, Imad Haloob, David C.H. Harris, Carmel M. Hawley, David W. Johnson, Vincent W. Lee, Jun Mai, Anna Rangan, Simon D. Roger, Kamal Sud, Eswari Vilayur, Gopala K. Rangan

“…However, the long-term perceptions of increasing water intake and the role of self-efficacy tools are unknown. Methods: Participants randomized to the increased water intake arm in a 3-year trial were purposively sampled and invited to semistructured interviews at the end of the study. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…The removal of aflatoxins from contaminated food is a major problem in livestock and poultry nutrition and the pollution removal methods are based on the decomposition, destruction, inactivation, or removal of aflatoxins through biological, chemical, or physical methods. …”
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Prevalence of neglected tropical diseases among migrants living in Europe: A systematic review and meta-analysis by Giacomo Guido, Luisa Frallonardo, Sergio Cotugno, Elda De Vita, Giulia Patti, Laura De Santis, Francesco Vladimiro Segala, Emanuele Nicastri, Federico Gobbi, Anna Morea, Francesca Indraccolo, Domenico Otranto, Ana Requena-Mendez, Nicola Veronese, Annalisa Saracino, Francesco Di Gennaro, Roberta Iatta

“…Test-and-treat strategies appear promising, yet more comprehensive efforts are necessary. Establishing a European NTD registry could improve monitoring and management. …”
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Serum Galactomannan: A Predictor of Poor Outcomes in Peritoneal Dialysis Patients With Fungal Peritonitis by Talerngsak Kanjanabuch, Tanawin Nopsopon, Thunvarat Saejew, Athiphat Banjongjit, Pongpratch Puapatanakul, Somkanya Tungsanga, Jakapat Vanichanan, Sajja Tatiyanupanwong, Kanjana Tianprasertkij, Worapot Treamtrakanpon, Uraiwan Parinyasiri, Kamol Khositrangsikun, Oranan Thamvichitkul, Pichet Lorvinitnun, Sriphrae Uppamai, Rhonachai Lawsuwanakul, Mananya Wanpaisitkul, Saowalak Chowpontong, Rutchanee Chieochanthanakij, Somchai Eiam-Ong, Jeffrey Perl, David W. Johnson

“…Patients who died had significantly higher posttreatment serum GMI levels and were more likely to have positive GMI after treatment. …”
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Metazoan diversity in Chilean hypersaline lakes unveiled by environmental DNA by Mattia Saccò, Mattia Saccò, Mattia Saccò, Matthew A. Campbell, Pablo Aguilar, Pablo Aguilar, Pablo Aguilar, Gonzalo Salazar, Gonzalo Salazar, Gonzalo Salazar, Tina E. Berry, Tina E. Berry, Matthew J. Heydenrych, Angus Lawrie, Nicole E. White, Chris Harrod, Chris Harrod, Chris Harrod, Morten E. Allentoft, Morten E. Allentoft

“…Compared to net-based assessments, eDNA analysis allowed more refined taxonomic assignments for copepods and ostracods, while certain taxa such as Ephydridae or Hirudinea were not detected through molecular tests. …”
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Hospitalized patients and stimulant use-associated heart failure: importance of ejection fraction and related risk factors by Akshat Agrawal, Brooke Scardino, Diensn G. Xing, Md. Shenuarin Bhuiyan, Md. Shenuarin Bhuiyan, Rick A. Bevins, Kalgi Modi, Tarek Helmy, Steven A. Conrad, Steven A. Conrad, Nicholas E. Goeders, Md Mostafizur Rahman Bhuiyan, John A. Vanchiere, John A. Vanchiere, A. Wayne Orr, A. Wayne Orr, Christopher G. Kevil, Christopher G. Kevil, Mohammad Alfrad Nobel Bhuiyan, Mohammad Alfrad Nobel Bhuiyan, Mohammad Alfrad Nobel Bhuiyan

“…Our study also compares demographic and comorbidities between the HF subtypes.MethodsNational Inpatient Sample data from 2008 to 2020 were used to identify hospital admissions among stimulant users with HF. …”
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Extrinsic and intrinsic drivers of prevalence and abundance of hard-bodied ticks (Acari: Ixodidae) in one-humped camel (Camelus dromedarius) by Rachid Chaibi, Nora Mimoune, Farouk Benaceur, Latifa Stambouli, Lamine Hamida, Rabah Khedim, Radhwane Saidi, Mohammed Hocine Benaissa, Hicham Gouzi, Souad Neffar, Haroun Chenchouni

“…The sampled camels, which ranged in age from 6 days to 21 years, were examined for tick infestations. …”
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Assessing the utilization of HIV genotype resistance testing: Insight from Italian Infectious Diseases Units by Andrea De Vito, Antonia Bezenchek, Rossana Scutari, Luna Colagrossi, Giacomo Valenti, Maria Concetta Bellocchi, Luca Pipitò, Sergio Ferrara, Sergio Malandrin, Monica Tallarita, Alessandro Cozzi-Lepri, Francesca Ceccherini-Silberstein, Sergio Lo Caputo, Stefano Rusconi

“…Purpose: We aimed to assess the utilization of genotype resistance testing (GRT) by Infectious Diseases Units across Italy. Methods: A cross-sectional study was conducted involving a questionnaire distributed to the Infectious Diseases Unit in Italy. …”
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Implementation of the American- College of Physicians Guideline for Low Back Pain (IMPACt-LBP): protocol for a healthcare systems embedded multisite pragmatic cluster-randomised tr... by Shelby D Reed, Adam P Goode, Rowena J Dolor, Barcey T Levy, Stacie A Salsbury, Christine Goertz, Hrishikesh Chakraborty, Samuel Broderick, Kelley Ryan, Sharon Settles, Shoshana Hort, Elizabeth A Chrischilles, Stacie Kasper, James E Stahl, Chandra Almond, Zacariah Shannon, Debra Harris, Jeanette Daly, Patricia Winokur, Jon D Lurie

“…LBP is one of the leading causes of ambulatory care visits to US physicians; problematically, these visits often result in treatments such as opioids, surgery or advanced imaging that can lead to more harm than benefit. The American College of Physicians (ACP) Guideline for Low Back Pain recommends patients receive non-pharmacological interventions as a first-line treatment. …”
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Survey of VA healthcare facilities to assess organizational readiness to change assessment (ORCA) and challenges to implementing antibiotic stewardship by Tyler J. Brehm, Eva Amenta, Larissa Grigoryan, Sophia Braund, Jonah Pesikoff, Rogelio Hernandez, David Ramsey, Vanessa W. Stevens, John P. Donnelly, Aanand D. Naik, Barbara W. Trautner

“…Level 3 facilities reported significantly more antibiotic stewardship challenges (median = 10, interquartile range [IQR] = 4.5–11.2) versus levels 1 and 2 (median = 3, IQR 2.0–5.7, P = 0.004). …”
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Functional regulation of macrophages by Ces1d-mediated lipid signaling in immunometabolism by Long J. Shao, Fathima Elizondo, Feng Gao, Rabie Habib, Xin Li, Katherine Pham, Jazmin Ysaguirre, Maryam Elizondo, Shirindokht Shirazi, Kristin L. Eckel-Mahan, Sean Hartig, Huaizhu Wu, Kai Sun

“…Adipose tissue, liver, and serum samples were analyzed histologically and biochemically. …”
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Potential of digital applications for self-management and other outcomes in inflammatory rheumatic diseases: a systematic literature review by Alina Volkmar, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Stefan Kleinert, Stefan Kleinert, Kirsten Karberg, Kirsten Karberg, Georg Gauler, Georg Gauler, Michael Klennert, Jana Klennert, Peer Malte Aries, Peer Malte Aries, Sonja Froschauer, Sarah Wildenhain, Theresia Muth, Susanna Späthling-Mestekemper, Susanna Späthling-Mestekemper, Christoph Kuhn, Christoph Kuhn, Wolfgang Vorbrüggen, Wolfgang Vorbrüggen, Martin Welcker, Martin Welcker, Peter Bartz-Bazzanella, Peter Bartz-Bazzanella, Matthias Englbrecht

“…However, significant heterogeneity and limited generalizability highlight the need for more robust and long-term research to validate the efficacy of specific tools and identify best options for improving outcomes. …”
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Patient-derived gastric cancer organoids model heterogeneity and stroma-mediated chemoresistance in poorly cohesive carcinoma by Yi Yin, Yi Yin, Shuhong Zeng, Shuhong Zeng, Shuhong Zeng, Hui Zhang, Hui Zhang, Shuangshuang Wang, Fei Ke, Qiang Rui, Jinyong Zhou, Yuwen Zhuang, Weixing Shen, Weixing Shen, Jun Qian, Jun Qian, Shenlin Liu, Shenlin Liu

“…In this study, we constructed a panel of patient-derived organoids of GC and used them to understand histological accuracy and sensitivity profiles as well as the influence of microenvironment on these special GC subtypes.MethodsA total of 23 patient-derived GC organoid models including 12 PCC and 11 non-poorly cohesive carcinoma (NPCC) were established. …”
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Differential inflammatory responses to acute exercise and ex vivo immune challenge in young and master athletes by Luciele Guerra Minuzzi, Luciele Guerra Minuzzi, Luciele Guerra Minuzzi, Alexandre Abilio De Souza Teixeira, Caique Figueiredo, Gilson Dorneles, Gilson Dorneles, Anna Cláudia Castelo Branco, Bruna Spolador de Alencar Silva, Pedro L. Valenzuela, Pedro L. Valenzuela, Alessandra Peres, Alejandro Lucia, Alejandro Lucia, Maria Notomi Sato, José Cesar Rosa Neto, Karsten Krüger, Fabio Santos Lira, Fabio Santos Lira

“…Therefore, we aimed to compare the inflammatory responses to ex vivo whole blood and peripheral blood mononuclear cells [PBMCs] cultures from young and master athletes, before and after a single bout of moderate-intensity exercise.MethodsYoung (n=7; 22 ± 4 years) and master (n=12; 52 ± 9 years) female and male athletes with similar performance levels performed a 30-minute bout of moderate-intensity exercise. …”
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Multicenter cross-sectional study of HTLV-1 prevalence and associated risk factors in epidemiologically relevant groups across Brazil by Carlos Brites, Prince Baffour Tonto, Prince Baffour Tonto, Antonio C. Vallinoto, Onayane dos Santos Oliveira, Simone Simionatto, Monica Bay, Tania Reuter, Monica M. Gomes-da-Silva, Melissa Medeiros, Melissa Medeiros, Rafaela Mayoral, Estela Luz, Michael Rocha, Hareton Vechi, Hareton Vechi, Bobby Brooke Herrera, Bobby Brooke Herrera, Bobby Brooke Herrera

“…While previous research has focused on either specific cities or populations, there is a need for multicenter studies encompassing epidemiologically relevant populations to ascertain more accurate prevalence rates and predictors of HTLV-1 infection in the country.MethodsWe conducted a multicenter, cross-sectional study involving 3,184 participants across seven cities and five study populations in Brazil. …”
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Prevalence and determinants of anaemia in South Asian diaspora women residing in Hong Kong: An exploratory cross-sectional study by Gary Ka-Ki Chung, Bulbul Sharma, Danna Camille Vargas, Woohyung Lee, Kai Sing Sun, Heidi Hung, Hasiba Munir, Soniya Pun, Mariem Sharif, Lee Sha Tong, Tsz Lui Tang, Man Hin Chio, Chi Yui Wong, Eliza Lai-Yi Wong, Dong Dong, Eng-Kiong Yeoh

“…Findings supported the independent protective role of better diet quality against anaemia severity (aOR=0.40 [95 % CI = 0.22, 0.73] for high diet quality compared to poor diet quality), and that women of reproductive age (aOR=2.36 [1.03, 5.44] for the 35–44 age group compared to the youngest group), having a larger household size (aOR=1.11 [1.01,1.21] per person increase), and staying for a longer period in Hong Kong (aOR=1.83 [1.07, 3.13] for > 7 years compared to < 3 years) were associated with more severe anaemia. Conclusion: The high prevalence of anaemia in our sampled South Asian women in Hong Kong, especially those of reproductive age, was partly attributable to nutrition, acculturation, and cultural preference on larger family size, beyond potential genetic predisposition.…”
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Receipt of medications for opioid use disorder among rural and urban veterans health administration patients by Olivia C. Reynolds, Kathleen F. Carlson, Adam J. Gordon, Robert L. Handley, Benjamin J. Morasco, Todd P. Korthuis, Travis I. Lovejoy, Jessica J. Wyse

“…The analytic sample included all patients diagnosed with OUD from 10/1/2018–9/30/20. …”
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