Epidemiology and genetic diversity of common human coronaviruses in Beijing, 2015-2023: A prospective multicenter study by Qi Huang, Lu Kang, Xiaofeng Wei, Cheng Gong, Hui Xie, Maozhong Li, Yiting Wang, Mei Dong, Fang Huang

“…ABSTRACT: Objectives: To investigate the epidemiological and genetic features of common human coronaviruses (HCoVs) in Beijing in the context of the COVID-19 pandemic. Methods: We collected clinical samples from patients with acute respiratory tract infections (ARTIs) in 35 sentinel hospitals from 2015 to 2023. …”
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Demonstration of T-Cell Monotypia Using Anti-TCRbeta1/2 (<i>TRBC1</i>/2) Immunostaining as a Rapid and Cost-Effective Alternative to PCR-Based Clonality Studies for the Diagnosis o... by Elizabeth J. Soilleux, Daniel T. Rodgers, Jinlong J. Situ, Shelley C. Evans, Venkata N. Konda, Han-Chieh Yang, Jianxiong Pang, Isabella Gilbey Smith, Pete Rajesh, Maryam Salimi, Soo Weei Ng, Julia Jones, Jodi L. Miller, Rachel Etherington, Margaret Ashton-Key, Graham Ogg

“…Results: Our TCRbeta1/TCRbeta2 antibody pair gave highly specific FFPE tissue staining. All benign samples analyzed (immunohistochemically, by BaseScope^TM, by Q-PCR, and by RNAseq data analysis) had TCRbeta1/TCRbeta2 or <i>TRBC1/TRBC2</i> ranges well within the previously published flow cytometric benign range (TCRbeta2/TCRbeta1 = 0.18:1–5.7:1), while samples of T-cell lymphoma did not. …”
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Associations of endocrine-disrupting chemicals mixtures with serum lipid and glucose metabolism among overweight/obese and normal-weight children: A panel study by Yuanyuan Zhang, Biao Zhang, Huihua Yang, Miao Liu, Jie Wang, Lei Zhao, Wenting Guo, Meng Li, Xuefeng Lai, Liangle Yang, Xiao Meng, Cuijuan Wang, Zhihu Zhang, Xiaomin Zhang

“…For each visit, participants provided morning urine samples for 4 consecutive days and fasting blood samples on day 4. …”
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Development of a pan-genotypic monoclonal antibody-based competitive ELISA for the detection of antibodies against Bovine viral diarrhea virus by Shuhui Qi, Shuhui Qi, Jing Wang, Jing Wang, Ting Le, Chao Sun, Jitao Chang, Jitao Chang, Zhigang Jiang, Xin Yin, Quanhai Pang

“…IntroductionBovine viral diarrhea virus (BVDV), a positive-sense single-stranded RNA virus, causes significant economic losses in the cattle industry. Current diagnostic methods for BVDV exhibit variable sensitivity and specificity, underscoring the need for more rapid and accurate detection approaches. …”
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Dietary and lifestyle patterns identified through reduced rank regression and their association with insulin-related disorders: a prospective analysis from the Tehran Lipid and Glu... by Ebrahim Mokhtari, Hossein Farhadnejad, Farshad Teymoori, Mitra Kazemi Jahromi, Mehrnaz Nikkhah, Parvin Mirmiran, Fereidoun Azizi

“…It is suggested that further studies with a larger sample size and more extended follow-up duration, especially in other populations with different lifestyles and food habits be performed to confirm the findings of the current study.…”
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Clinical pharmacists’ interventions about drug therapy problems and its acceptability by prescribers among pediatric hospitalized patients with infectious diseases in resource-limi... by Tilaye Arega Moges, Samuel Berihun Dagnew, Sisay Sitotaw Anberbr, Getachew Yitayew Tarekegn, Taklo Simeneh Yazie, Getu Tesfaw Addis, Teklie Mengie Ayele, Kidist Hunegn Setargew, Fisseha Nigussie Dagnew

“…Cipolle’s and Strand’s DTP classification methods were used for the identification of DTPs. …”
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Analyzing Usage of the Metaverse by Associations of Patients With Prostate Cancer During the 2023 Blue Ribbon Campaign: Cross-Sectional Survey Study by Jung Ki Jo, Yeeun Kim, Yun-Sok Ha, Kwang Taek Kim, Sangjun Yoo, Woo Suk Choi, Jihye Yang, Jaeeun Shin, Sun Il Kim, Jeong Hyun Kim

“…Despite these encouraging results, limitations, such as the sample being skewed toward younger participants and reliance on self-reported data, underscore the need for more rigorous and multidimensional assessment strategies. …”
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Integrated weed control (chemical & mechanical) in chickpea (Cicer arietinum L.) under Shoushtar conditions by adel modhej, zahra alikhani galeh

“…The present report describes the effect of integrated methods on weed density and grain yield of chickpea under Shoushtar conditions. …”
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Correlation Between Human Body Fat Distribution and Carotid Atherosclerosis by QI Yanmeng, LI Dandan, CHEN Anqi, YANG Han, LI Yan

“…However, there were no significant correlations between waist-to-hip ratio, visceral fat area, and carotid atherosclerosis(P > 0.05).ConclusionsThere is a significant correlation between trunk fat/limb fat and the occurrence of carotid atherosclerosis. In the future, the sample size should be expanded, and more precise methods for measuring fat distribution should be adopted to validate the conclusions of this study.…”
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Features of the Formation of Seroprevalence to SARS-CoV2 in the Population of the Republic of Tatarstan during the Spread of COVID-19 by I. D. Reshetnikova, E. V. Agafonova, N. M. Khakimov, Yu. A. Tyurin, N. D. Shaуkhrazieva, V. B. Ziatdinov

“…Statistical processing were carried out using the methods of variation statistics using the Excel statistical package and the WinPepi software product (version 11.65). …”
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Profiling triple-negative breast cancer-specific super-enhancers identifies high-risk mesenchymal development subtype and BETi-Targetable vulnerabilities by Qing-shan Chen, Rui-zhao Cai, Yan Wang, Ge-hao Liang, Kai-ming Zhang, Xiao-Yu Yang, Dong Yang, De-Chang Zhao, Xiao-Feng Zhu, Rong Deng, Jun Tang

“…This study aims to investigate SE heterogeneity in TNBC and its influence on BETi effectiveness, with the goal of advancing BETi precision treatment strategies and enhancing therapeutic efficacy. Methods We conducted a comprehensive analysis of H3K27ac ChIP-Seq data from TNBC cell lines and clinical samples, integrating multiple bulk RNA-Seq, scRNA-Seq, and stRNA-Seq datasets to characterize the SE landscape and heterogeneity in TNBC. …”
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How firearm legislation impacts firearm mortality internationally: A scoping review by Brianna Greenberg, Alexandria Bennett, Asad Naveed, Raluca Petrut, Sabrina M. Wang, Niyati Vyas, Amir Bachari, Shawn Khan, Tea Christine Sue, Nicole Dryburgh, Faris Almoli, Becky Skidmore, Nicole Shaver, Evan Chung Bui, Melissa Brouwers, David Moher, Julian Little, Julie Maggi, Najma Ahmed

“…Our objective was to document the extent and nature of evidence on the impact of firearm legislation on mortality from firearm violence. Methods: A scoping review was conducted under PRISMA-ScR guidance. …”
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Emergence of plasmid-mediated tigecycline resistance tet(X4) gene in Enterobacterales isolated from wild animals in captivity by Lei Lei, Panfeng Xiong, Zelin Yan, Yanyan Zhang, Yuchen Wu, Gongxiang Chen, Houhui Song, Rong Zhang

“…However, the presence and molecular characteristics of tet(X)-carrying bacteria in these animals remain unknown. Methods: Eighty-four samples were collected from captive wild animals. tet(X) variants were detected using polymerase chain reaction and the isolates were identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. …”
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Proteomic Profiling of Human Peripheral Blood Cell Targets of IgG Induced by SARS-CoV-2: Insights into Vaccine Safety by Nicolle Rakanidis Machado, Lais Alves do Nascimento, Beatriz Oliveira Fagundes, João Vitor da Silva Borges, Fabio da Ressureição Sgnotto, Isabella Siuffi Bergamasco, Juliana Ruiz Fernandes, Thalyta Nery Carvalho Pinto, Anna Julia Pietrobon, Gil Benard, Maria Notomi Sato, Jefferson Russo Victor

“…This study investigates the IgG autoantibody responses in patients with varying severities of COVID-19 infection and compares these responses with vaccinated individuals. Methods: We utilized proteomic profiling to analyze autoantibody reactivity against a broad spectrum of proteins expressed in lymphoid and myeloid cell subsets in serum samples from severe and moderate COVID-19 patients, as well as vaccinated individuals who received the inactivated CoronaVac (Sinovac) vaccine. …”
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Clinical and fertility outcomes in lynch syndrome patients with endometrial carcinoma or endometrial Intraepthelial neoplasia treated with fertility sparing management by Hadley W. Reid, Alexandria N. Young, Sophia H. Yin, Isabela Covelli Velez, Mary Kathryn Abel, David L. Kolin, Elizabeth S. Ginsburg, Matthew B. Yurgelun, Colleen Feltmate, Jessica D. St Laurent

“…Progesterone response rates appear to be lower than those in sporadic cases, though similar clinical and histologic factors (age, BMI, and p53 expression pattern) may predict disease regression and fertility outcomes. A larger sample and standardized treatment paradigm are needed to provide more evidence on fertility sparing management for LS patients.…”
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Aberrant fragmentomic features of circulating cell-free mitochondrial DNA enable early detection and prognosis prediction of hepatocellular carcinoma by Yang Liu, Fan Peng, Siyuan Wang, Huanmin Jiao, Kaixiang Zhou, Wenjie Guo, Shanshan Guo, Miao Dang, Huanqin Zhang, Weizheng Zhou, Xu Guo, Jinliang Xing

“…Methods Capture-based mtDNA sequencing was carried out in plasma cell-free DNA samples from 1168 participants, including 571 patients with HCC, 301 patients with chronic hepatitis B or liver cirrhosis (CHB/LC) and 296 healthy controls (HC). …”
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The SDSS-V Local Volume Mapper: Data Analysis Pipeline by Sebastián F. Sánchez, Alfredo Mejía-Narváez, Oleg V. Egorov, Kathryn Kreckel, Niv Drory, Guillermo A. Blanc, J. Eduardo Méndez-Delgado, Jorge K. Barrera-Ballesteros, Hector Ibarra-Medel, Dmitry Bizyaev, Pablo García, Aida Wofford, Alejandra Z. Lugo-Aranda

“…To assess the accuracy of our results, we compare them with both idealized and more realistic simulations, highlighting the limitations of our methods. …”
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Deep learning helps discriminate between autoimmune hepatitis and primary biliary cholangitis by Alessio Gerussi, Oliver Lester Saldanha, Giorgio Cazzaniga, Damiano Verda, Zunamys I. Carrero, Bastian Engel, Richard Taubert, Francesca Bolis, Laura Cristoferi, Federica Malinverno, Francesca Colapietro, Reha Akpinar, Luca Di Tommaso, Luigi Terracciano, Ana Lleo, Mauro Viganó, Cristina Rigamonti, Daniela Cabibi, Vincenza Calvaruso, Fabio Gibilisco, Nicoló Caldonazzi, Alessandro Valentino, Stefano Ceola, Valentina Canini, Eugenia Nofit, Marco Muselli, Julien Calderaro, Dina Tiniakos, Vincenzo L’Imperio, Fabio Pagni, Nicola Zucchini, Pietro Invernizzi, Marco Carbone, Jakob Nikolas Kather

“…Attention heatmaps showed that ALNE tends to focus more on areas with increased inflammation, associating such patterns predominantly with AIH. …”
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Identification of Patients With Congestive Heart Failure From the Electronic Health Records of Two Hospitals: Retrospective Study by Daniel Sumsion, Elijah Davis, Marta Fernandes, Ruoqi Wei, Rebecca Milde, Jet Malou Veltink, Wan-Yee Kong, Yiwen Xiong, Samvrit Rao, Tara Westover, Lydia Petersen, Niels Turley, Arjun Singh, Stephanie Buss, Shibani Mukerji, Sahar Zafar, Sudeshna Das, Valdery Moura Junior, Manohar Ghanta, Aditya Gupta, Jennifer Kim, Katie Stone, Emmanuel Mignot, Dennis Hwang, Lynn Marie Trotti, Gari D Clifford, Umakanth Katwa, Robert Thomas, M Brandon Westover, Haoqi Sun

“…Automated analysis of medical records through natural language processing (NLP) enables more efficient adjudication but has not yet been validated across multiple sites. …”
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Analyzing petrographic characteristics and trace element distribution of high-purity quartz deposits from the Peshawar Basin, Pakistan: insights into processing and purification te... by I. Khan, X. Yang, X. Yang, X. Yang, M. Xia, Z. Hou

“…<p>This study examined the potential of quartz vein ore from the Peshawar Basin, Pakistan, as a raw material for producing high-grade, high-purity quartz sand. These samples were purified using a combination of methods including crushing, magnetic separation, ultrasonic cleaning, flotation, high-temperature calcination, water quenching, and acid leaching. …”
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