QUALITY CONTROL EVALUATION OF LEUCODEPLETED RED BLOOD CELL COMPONENTS PREPARATION WITH TOP AND BOTTOM TECHNIQUE IN GSH BLOOD BANK IN SAO PAULO, BRAZIL by MS Aline, Akil-Fabiana, R Eduardo, AD Santos-Janaina, F Felipe, S Paula, García-Rebecca, Vianna-Thiago, Frontier-Ludwig, Moreno-Dalia

“…According to local and European standards (EDQM), these results presented more than 90% compliance, as follows: Volume: 99.98%, Hb: 99.95%, rWBC: 100%. …”
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Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease by Yuqi Qiu, Diane M. Jacobs, Karen Messer, David P. Salmon, Cheryl L. Wellington, Sophie Stukas, Carolyn Revta, James B. Brewer, Gabriel C. Léger, Brianna Askew, Lia Donahue, Stephen Kaplita, Vladimir Coric, Irfan A. Qureshi, Howard H. Feldman, The Alzheimer’s Disease Cooperative Study T2 Protect AD Study Group

“…Modeling of biomarker-informed power calculations revealed that including high NfL as a trial entry criterion could substantially reduce requisite trial sample size. Conclusions Elevated baseline plasma NfL predicted more rapid clinical decline and MRI volume loss. …”
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Correlation between interleukins in aqueous humor and vitreous humor of vitreoretinal lymphoma patients by Yurun Liu, Xinyi Zhou, Kaiyu Zhang, Shixue Liu, Ruiwen Li, Yifan Gong, Zhujian Wang, Tingting Jiang, Ting Zhang, Gezhi Xu, Junxiang Gu, Qing Chang

“…Methods This was a case series study. Reviewed were consecutive biopsy-proven B-cell VRL cases of which adequate paired AqH and VH samples were obtained for the measurement of interleukin 10 (IL-10) and interleukin 6 (IL-6). …”
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Healthcare Workers and Nonhealthcare Workers Pro-Vaccination Attitude and Its Associated Factors towards COVID-19 Vaccine Globally: A Systematic Review and Meta-Analysis by Addisu Dabi Wake

“…The aim of this systematic review and meta-analysis were to determine the global pro-vaccination attitude and associated factors towards COVID-19 vaccine among healthcare workers (HCWs) and nonhealthcare workers (non-HCWs). Methods. Different databases such as PubMed, Scopus, EMBASE, and Google Scholar were used. …”
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Increased <i>MAGE-C</i> Family Gene Expression Levels as a Biomarker of Colon Cancer Through the Demethylation Mechanism by Mikhlid H. Almutairi, Waad A. Alsoraie, Turki M. Alrubie, Ahmad S. Alkhaldi, Nada S. Alhajri, Monira A. Alaujan, Manar H. Almutairi, Bader O. Almutairi

“…The goal was to assess their potential use as cancer biomarkers for the early detection and improvement of CC treatment. Methods: <i>MAGE-C1</i>, <i>MAGE-C2</i>, and <i>MAGE-C3</i> family gene expression levels were examined using RT-PCR and qRT-PCR assays in 26 adjacent normal colon (NC) and CC tissue samples from male and female Saudi patients. …”
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CD66b⁺ Tumor-Infiltrating Neutrophil-like Monocytes as Potential Biomarkers for Clinical Decision-Making in Thyroid Cancer by Hamdullah Yanik, Ilgin Demir, Ertugrul Celik, Ece Tavukcuoglu, Ibrahim Burak Bahcecioglu, Adile Begum Bahcecioglu, Mehmet Mert Hidiroglu, Sumeyra Guler, Nese Ersoz Gulcelik, Mehmet Ali Gulcelik, Kerim Bora Yilmaz, Gunes Esendagli

“…CD66b⁺ neutrophil-like monocytes constitute a novel subset of myeloid cells that are implicated in the modulation of anti-tumor immune responses, but their role in thyroid cancer remains unclear. <i>Materials and Methods:</i> Peripheral blood and thyroid nodule tissue samples were obtained from 24 patients with papillary thyroid carcinoma, and from 10 patients who underwent surgery for symptoms of tracheal compression due to benign thyroid nodules. …”
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Changes in tree-ring wood density of European beech (Fagus sylvatica L.), silver fir (Abies alba Mill.), and Norway spruce (Picea abies (L.) H. Karst.) in European mountain forests... by Chiara Torresan, Torben Hilmers, Admir Avdagić, Edmondo Di Giuseppe, Matija Klopčič, Mathieu Lévesque, Florian Motte, Enno Uhl, Tzvetan Zlatanov, Hans Pretzsch

“…., tree-ring width, current tree diameter, and latewood to earlywood ratio) and drought events on wood density. Methods In total, 150 tree cores were sampled from mountain forests in Bulgaria, Bosnia and Herzegovina, Slovenia, Switzerland, and Germany. …”
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Effects of YouTube Health Videos on Mental Health Literacy in Adolescents and Teachers: Randomized Controlled Trial by Rebekka Schröder, Tim Hamer, Victoria Kruzewitz, Ellen Busch, Ralf Suhr, Lars König

“…ObjectiveThe study evaluates the effectiveness of a short educational YouTube Health video for promoting mental health literacy in adolescents and teachers. MethodsTwo independent samples of 352 adolescents and 502 teachers from Germany were recruited from a large panel, representative of the German population with internet access. …”
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Experiences Receiving and Delivering Virtual Health Care For Women: Qualitative Evidence Synthesis by Karen M Goldstein, Sharron Rushton, Allison A Lewinski, Abigail Shapiro, Tiera Lanford-Davey, Jessica N Coleman, Neetu Chawla, Dhara B Patel, Katherine Van Loon, Megan Shepherd-Banigan, Catherine Sims, Sarah Cantrell, Susan Alton Dailey, Jennifer M Gierisch

“…ConclusionsThe benefits of virtual care for health care access may be more acutely felt by women, especially those with preexisting challenges. …”
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Proposing a two-stage screening approach to distinguish between transient and enduring postnatal depressive symptoms: A prospective cohort study by Johanne Smith-Nielsen, Ida Egmose, Stephen Matthey, Maria Stougård, Sophie Reijman, Mette Skovgaard Væver

“…Three research questions were addressed: Can the ''transient phenomenon'' be replicated in a postnatal sample? Can initial screening data predict transient status? …”
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Effects of Tanreqing injection against ventilator-associated pneumonia: a meta-analysis and systematic review of clinical studies by Pochen Li, Yang Wu, Danxia Ge, Ruyi Xu, Qianping Zhang, Yujiao Li, Lingyao Zhang, HsuanChieh Peng, Fangyu Yu

“…However, some of the included clinical studies had limitations such as small sample sizes, lack of sample size calculations. Therefore, future study designs should be more rigorous to enhance the reliability of findings.Systematic Review Registration:https://inplasy.com/inplasy-2025-2-0008/.…”
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Microplastics in rice: a systematic review by Iva Ferreira-Marques, Sara A. M. Silva, Joana C. Prata

“…There is a pressing need for more comprehensive studies to better understand the contamination pathways and improve statistical data on MP contamination in staple foods. …”
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Characterization of tongue coating microbiome from patients with colorectal cancer by Qubo Chen, Xiaoting Huang, Haiyan Zhang, Xuanting Jiang, Xuan Zeng, Wanhua Li, Hairong Su, Ying Chen, Fengye Lin, Man Li, Xiangyu Gu, Huihui Jin, Ruohan Wang, Dechang Diao, Wei Wang, Jin Li, Sufen Wei, Weizheng Zhang, Wofeng Liu, Zhiping Huang, Yusheng Deng, Wen Luo, Zuofeng Liu, Beiping Zhang

“…However, little is known on the relationship between tongue coating microbiome and colorectal cancer (CRC).Methods Metagenomic shotgun sequencing was performed on tongue coating samples collected from 30 patients with CRC, 30 patients with colorectal polyps (CP), and 30 healthy controls (HC). …”
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Prevalence, risk factors, and zoonotic implications of gastrointestinal parasites in urban cats in Kazakhstan: A cross-sectional multicity study by Lyudmila A. Lider, Vladimir Kiyan, Dinara M. Seitkamzina, Altay Ussenbayev, Botakoz E. Akmambaeva, Rabiga S. Uakhit, Nellya E. Mannapova, Igor Sytnik, Christian Bauer

“…This study aimed to determine the prevalence, species diversity, and risk factors of intestinal parasitic infections in urban cat populations across five major cities in Kazakhstan, thereby supporting the One Health framework for the prevention of zoonotic diseases. Materials and Methods: A cross-sectional survey was conducted from August 2023 to January 2025, involving 1,301 fecal samples collected from both client-owned and stray cats in Almaty, Astana, Oral, Qostanai, and Shymkent. …”
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Dynamic UAV data fusion and deep learning for improved maize phenological-stage tracking by Ziheng Feng, Jiliang Zhao, Liunan Suo, Heguang Sun, Huiling Long, Hao Yang, Xiaoyu Song, Haikuan Feng, Bo Xu, Guijun Yang, Chunjiang Zhao

“…Most phenological monitoring methods are post–seasonal and heavily rely on high–frequency time–series data. …”
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Digital Storytelling and Students’ Academic Engagement in Civic Education: Implications for Sustainable Development by Celestine Nkanu, David Francis Ekpoto, Amina Peter Adams, Idorenyin Edet Johnson, Anthony Etta Bisong, Odim Otu Offem, Efut Etim Nkanu, Fredrick Awhen Opoh, Samuel Manyo Takon, Agnes Edet Asuquo Offiong, James Eburikure Olayi, Samuel Orim Orim, Flora Michael Monity, James Abua Ewa, Oyobo-Gladys Tom Abam, John Edogi Egbe, Akaninyene Billy Orok, Joseph Enyia Ekpang

“…This research used a sample of 183 students, including 85 males and 98 females, selected by purposive and simple random selection methods. …”
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Proteolytic Activity Inhibition in Gingival Fluid by Cysteine Protease Inhibitors Obtained from Egg White and <i>Fallopia japonica</i> Extract: An In Vitro Study by Maciej Siewiński, Maciej Dobrzyński, Krzysztof Gołąb, Maciej Janeczek, Łukasz Nieradko, Barbara Bażanów, Andrzej Rapak, Marius Boariu, Stefan-Ioan Stratul, Alla Belova, Sorina Mihaela Solomon, Renata Samulak, Monika Machoy

“…This research has the following aims: 1. to analyze in vitro the inhibition of cysteine protease activity in the gingival crevicular fluid (GCF) and 2. to compare the toxicity of natural raw inhibitors (obtained from <i>Fallopia japonica</i> plant and egg white) with chlorhexidine (CHX) using an MTS viability test. <b>Methods</b>: Samples of GCF were collected from healthy (N = 17) individuals and (N = 65) periodontal patients. …”
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Molecular analysis of influenza A(H3N2) in a remote tropical island during 2014-2019 to identify the frequency of introduction and local circulation by Sikandar Azam, Takeaki Imamura, Michiko Okamoto, Yusuke Sayama, Mayuko Saito, Mariko Saito-Obata, Clyde Dapat, Raita Tamaki, Christina Dahlia Joboco, Joanna Ina Manalo, Samantha Louise Bado, Joanne De Jesus Cornejo, Socorro Lupisan, Marianette Inobaya, Veronica Tallo, Beatriz P Quiambao, Hitoshi Oshitani

“…By conducting molecular analysis, this study aimed to identify A(H3N2) introduction events and the duration of local circulation in a geographically remote tropical island. Methods: Nasopharyngeal/nasal samples were collected from symptomatic children under 5 years old in a remote tropical island of the Philippines between 2014 and 2019. …”
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Tracing carriage, acquisition, and transmission of ESBL-producing Escherichia coli over two years in a tertiary care hospital by Minh Ngoc Nguyen, Beryl Primrose Gladstone, Giulia De Angelis, Michael Biggel, Basil Britto Xavier, Christine Lammens, Qiang Lin, Sandra Van Puyvelde, Herman Goossens, Samir Kumar-Singh, Youri Glupczynski, Yehuda Carmeli, Evelina Tacconelli, Surbhi Malhotra-Kumar, the SATURN WP1, 4, 5 study groups

“…PA- and HA-ESBL patients developed significantly more ESBL-E infections than ESBL-free patients (P < 0.001). …”
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A comparative study of blood pressure submission between mobilec app users and non-users in Romania: a pilot cohort study by Liviu Ionut Serbanoiu, Liviu Ionut Serbanoiu, Stefan Sebastian Busnatu, Stefan Sebastian Busnatu, Andreea Elena Lacraru, Andreea Elena Lacraru, Maria Alexandra Pana, Maria Alexandra Pana, Suzana Guberna, Suzana Guberna, Dragos Trache, Dragos Trache, Plesu Elena, Plesu Elena, Catalina Liliana Andrei, Catalina Liliana Andrei, Crina Sinescu, Crina Sinescu

“…However, limitations such as small sample size, potential self-selection bias, and lack of randomization must be considered. …”
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