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18341
Exploring the Relationship Between Public Social Media Accounts, Adolescent Mental Health, and Parental Guidance in England: Large Cross-Sectional School Survey Study
Published 2024-12-01“…ObjectiveThis study aims to investigate the association between having a public social media account and anxiety and depression in school-going adolescents. MethodsOverall, 80 secondary schools and further education colleges in England were sampled using a cross-sectional web-based survey as part of the 2023 OxWell Student Survey. …”
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18342
A Novel Oncogenic and Drug-Sensitive KIF5B-NTRK1 Fusion in Lung Adenocarcinoma
Published 2024-10-01“…Moreover, <i>KIF5B</i>-<i>NTRK1</i> gene chimera has been shown to be an oncogene, activating both the MAPK and PI3K/AKT signaling pathways. The biopsy sample was analyzed using various methods such as hematoxylin–eosin staining (HE), immunohistochemistry (IHC), fluorescence in situ hybridization (FISH), and next-generation sequencing (NGS) based on a 1267-gene panel. …”
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18343
Minimally invasive differential diagnosis of melanocytic intraocular neoplasms
Published 2023-12-01“…Purpose: to analyze the mutation frequency of the GNAQ/GNA11 gene in circulating tumor DNA and genotypes of the polymorphic marker C3435T of the ABCB1 gene in a large sample of patients with intraocular melanocytic neoplasms (IMN).Material and methods. …”
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18344
Potential liquid biopsy markers of exosomal microRNAs in renal interstitial fibrosis blood and urine
Published 2025-04-01“…Objective: To explore more and better liquid biopsy markers of exosomal microRNAs (exo-miRNAs) in renal interstitial fibrosis (RIF) and to preliminary investigate the biological functions and signaling pathways involved in these markers. …”
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18345
Dry needling as an adjunct treatment to multimodal rehabilitation protocol following rotator cuff repair surgery: a preliminary, randomized sham-controlled trial
Published 2024-12-01“…Future studies should consider different control groups, long-term follow ups, larger sample sizes, and more MTrP-DN sessions to better understand their potential impact. …”
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18346
PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience
Published 2025-08-01“…The youngest patient experienced a great improvement of his social life, interacting more with his peers, and started to work out at the gym and play basketball. …”
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18347
Analysis of Palatal Rugae Pattern in Angle’s Classification of Malocclusion using Dental Casts in Chengalpattu District, Southern India: A Cross-sectional Study
Published 2025-03-01“…According to mean±SD length of rugae significantly more (p-value <0.05) primary rugae were found in class I (1.39±1.34 mm) compared to class II (0.59±1.17 mm) and class III (0.5±0.97 mm). …”
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18348
CD24a knockout results in an enhanced macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses in tumor microenvironment in a murine triple-negative breast cancer model
Published 2025-08-01“…Targeting CD24a enhances macrophage- and CD8⁺ T cell-mediated anti-tumor immune responses and is associated with a shift in the TME toward a more immunogenic state, thereby suppressing tumor growth. …”
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18349
Assessment of specific T-cell immunity in patients who have been ill and vaccinated against COVID-19
Published 2022-04-01“…It should be noted that the response was more pronounced when meeting with M-and N-pepdids, compared with S-protein.22 out of 23 COVID-19 intact individuals had no T-cell immunity to coronavirus infection before vaccination, but one employee had a response to 3 proteins-M, N, S, which indicates that he had previously encountered the SARS-CoV-2 virus. …”
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18350
The mediating role of daily living ability and sleep in depression and cognitive function based on a structural equation model
Published 2025-04-01“…It extends upon existing research and provides evidence for new areas of intervention that may ameliorate and delay cognitive decline in the elderly. Methods Data were collected from a representative sample of 5,470 (aged 60 years and above) in Anhui Province from the 2019 Anhui Health and Life Expectancy Survey(AHLS). …”
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18351
Integrated analysis of single-cell, spatial and bulk RNA-sequencing identifies a cell-death signature for predicting the outcomes of head and neck cancer
Published 2024-11-01“…Patients in high CDRscore manifested worse overall survival, more active of epithelial mesenchymal transition, TGF-β-related pathways and hypoxia, higher transcription of T cell exhausted markers, and stronger TP53 mutation. …”
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18352
Dementia Moves: protocol for a feasibility study testing a physical rehabilitation program for long-term care residents with moderate to severe dementia
Published 2025-07-01“…Abstract Background Most long-term care (LTC) residents live with dementia and the proportion with more advanced cognitive impairment is increasing. …”
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18353
Prevalence and risk factors for long COVID among cancer patients: a systematic review and meta-analysis
Published 2025-01-01“…Fatigue, respiratory symptoms, myalgia, and sleep disturbance need to be more addressed and managed to reduce symptom burden on cancer patients and improve quality of life. …”
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18354
What Matters Most to Veterans When Deciding to Use Technology for Health: Cross-Sectional Analysis of a National Survey
Published 2025-08-01“…ObjectiveThis study aimed to understand what matters most to US military veterans when deciding whether to use digital health technologies (DHTs) such as mobile health apps or devices to manage their health and compare these factors between veterans with and without prevalent chronic physical and mental health conditions. MethodsWe conducted a cross-sectional analysis of survey data collected from a national sample of veterans who receive care from the Veterans Health Administration (VHA), which was predominantly gathered as part of the last wave of a larger longitudinal data collection effort. …”
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18355
Studying the pathogenic role of catecholamines in the development of retinopathy of prematurity on an experimental model of the disease
Published 2019-12-01“…The isolated retinal samples were homogenized in 10 volumes of 0.1 n HClO4 containing 50 pmol/ml (or more) of 3,4-dihydroxybenzylamine (DBA), using an ultrasonic homogenizer (Labsonic M, Sartorius), centrifuged at 2000g for 20 minutes, and the norepinephrine, dopamine and precursor of dopamine — L-3,4 dihydroxyphenylalanine (L-DOPA) were determined in the resulting supernatant. …”
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18356
Maintaining Resilience and Well-Being in the Era of Climate Change: Protocol of an Acceptability and Feasibility Pilot of the Bee Well Program for Treating Eco-Anxiety in Rural Chi...
Published 2025-07-01“…Those in rural areas are also more likely to be impacted by natural hazards, further underscoring the need to support this population. …”
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18357
Seroprevalence of dengue virus infection among febrile patients visiting healthcare facilities in the selected districts of Afar region, Northeast Ethiopia
Published 2025-07-01“…Sociodemographic data, clinical features and blood samples were collected from participants after obtaining informed consent or assent. …”
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18358
Heme oxygenase-1 polymorphisms associate with ischemic cardiac complications and all-cause mortality in type 1 diabetes
Published 2025-08-01“…For the -413A/T SNP, men with the AA genotype experienced ischemic cardiac events more frequently (21.0% vs. 17.4%, p = 0.044), but no differences were found for women or for men and women together. …”
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18359
Relationships among cortical activation, cognition, and blood biomarkers in two types of dementia determined using functional near-infrared spectroscopy
Published 2025-04-01“…Blood amyloid-β (Aβ)42 levels were significantly higher in the AD group (p = 0.023), whereas significantly more α-synuclein was expressed in the LBD group (p = 0.012). …”
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18360
Risk factors, management, and outcomes of amniotic fluid embolism: A multicountry, population-based cohort and nested case-control study.
Published 2019-11-01“…This study aimed to pool data from multiple countries in order to describe risk factors, management, and outcomes of AFE and to explore the impact on the findings of considering United Kingdom, international, and United States AFE case definitions.<h4>Methods and findings</h4>A population-based cohort and nested case-control study was conducted using the International Network of Obstetric Survey Systems (INOSS). …”
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