Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population by Liuxuan Li, Jun Ou, Yige Chen, Qian Chen, Manjun Luo, Tingting Wang, Yingfan Zhang, Jiabi Qin

“…Furthermore, maternal FAS may help to offset some of risks of CHD due to offspring MTRR genetic variants. However, more studies with prospective designs and larger samples are needed to confirm our findings. …”
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Investigating Potential Gender Differences in ChatGPT-Diagnosed Clinical Vignettes by Anjali Mediboina, Meghana Bhupathi, Keerthana Janapareddy

“…CONCLUSION: While the AI's responses were generally accurate and complete, the observed misdiagnoses of conditions such as PSVT and eating disorders highlight the need for a more thorough examination of potential biases in AI-driven chatbots. …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…We performed a one-sample Mendelian randomization using two-stage least-squares regression. …”
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Construction of a nomogram prediction model for the pathological complete response after neoadjuvant chemotherapy in breast cancer: a study based on ultrasound and clinicopathologi... by Pingjuan Ni, Yuan Li, Yu Wang, Xiuliang Wei, Wenhui Liu, Mei Wu, Lulu Zhang, Feixue Zhang

“…All patients underwent surgical resection after NAC6 and the samples were sent for histopathological and immunohistochemical examination. …”
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Integrated peripheral blood multi-omics profiling identifies immune signatures predictive of neoadjuvant PD-1 blockade efficacy in head and neck squamous cell carcinoma by Hao Zhang, Wenjie Wu, Meng Wang, Jie Zhang, Chuanbin Guo, Guojun Han, Lin Wang

“…The aim of this study is to develop a predictive model for neoadjuvant PD-1 therapy response in HNSCC patients using exclusively liquid biopsy approaches-namely, peripheral blood immune profiling (CyTOF) and plasma cytokine panels (Olink). Methods In a prospective trial involving 50 HNSCC patients treated with neoadjuvant tislelizumab plus chemotherapy, peripheral blood samples were collected pre- and post-treatment. …”
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HIIT versus MICT in MASLD: mechanisms mediated by gut-liver axis crosstalk, mitochondrial dynamics remodeling, and adipokine signaling attenuation by Dongkun Deng, Lin Xu, Yufei Liu, Chang Li, Qingfeng Jiang, Jiaming Shi, Shuo Feng, Yunhua Lin

“…It is noteworthy that HIIT was more effective in improving mitochondrial function in MASLD than MICT (P < 0.001). …”
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Determinants of tetanus immunization among pregnant women where tetanus has not been eliminated: a multilevel analysis of 6 countries by Werkneh Melkie Tilahun, Habtamu Geremew, Lamrot Yohannes Abay, Adugnaw Bantie Kebie, Mulat Belay Simegn

“…BackgroundTwo or more doses of the tetanus toxoid (TT) vaccine in pregnancy afford the fetus passive immunity and reduce neonatal mortality by 96%. …”
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The mediating role of self-compassion in the relationship between childhood trauma and the symptoms of body dysmorphic disorder by Motahhareh Kargar Shooroki, Azadeh Choobforoushzadeh, Azra Mohammadpanah Ardakan

“…A non-random convenience sample of 300 participants was selected. Data were collected using the Childhood Trauma Questionnaire (CTQ), the Yale-Brown Obsessive Compulsive Scale-Modified for BDD (BDD-YBOCS), and the Self-Compassion Scale (SCS). …”
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Evaluating hepatitis B screening, prevalence, vaccination coverage, and linkage to care in Abuja, Nigeria: insights from a cross-sectional study by Ogechukwu MaryAnn Akabuike, Mabel Kamweli Aworh, Nkiruka Lynda Uzoebo, John Erwat, Onyinyechi Agukwe, Kingsley Ngong, Amos Dangana, Kenneth Enwerem, Idris Nasir Abdullahi

“…Vaccination uptake declined with each subsequent dose, but more older participants completed the third dose. …”
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Faktor Risiko Asma Pada Murid Sekolah Dasar Usia 6-7 Tahun di Kota Padang by Afdal ., Finny Fitry Yani, Darfioes Basir, Rizanda Machmoed

“…If seeing the increased incidence of asthma, genetic factors might not play a role solely, but the environmental factors might play moreObjective The aim of this study was to determine the prevalence and the risk factors of asthma in elementary school children aged 6-7 years in Padang.Methods This research is cross sectional study in 20 elementary schools in Padang during June until November 2009, total sample of 879 students. …”
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The Efficacy of Remineralizing Materials on Artificial Enamel Lesions: An In Vitro Study by Gustė Klimaitė, Arūnas Vasiliauskas, Pranas Grinkevičius, Dominyka Grinkevičienė, Deivydas Šapalas

“…Remineralization of enamel was the highest in samples from the P11-4 group (54.1%), followed by the nano-HA group (35.4%), FV group (17.8%), and control group (11.2%). …”
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The role of vitamin D in treated and refractory ulcerative colitis patients: a case-control study by Amjad Ahmadi, Leili Shokoohizadeh, Farshad Sheikhesmaili, Bahram Nikkhoo, Asadollah Mohammadi, Mohammadali Khan Mirzaei, Mohammad Yousef Alikhani, Rasoul Yousefimashouf

“…Future studies should aim for larger cohorts to provide more definitive insights into this important issue.…”
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Molecular Detection and Clinical Impact of <i>Helicobacter pylori</i> Virulence Genes in Gastric Diseases: A Study in Arequipa, Peru by Yuma Ita-Balta, Alice Zegarra-Adanaque, Johany Sanchez-Guillen, Miguel Farfán-Delgado, Carlos Ortiz-Castro, Alexis Germán Murillo Carrasco, Alejandro Miranda Pinto, Cecilia Manrique-Sam

“…This study investigates the prevalence, distribution, and clinical relevance of its key virulence genes, <i>vacA</i> and <i>cagA</i>, in a Peruvian patient cohort. <b>Materials and Methods</b>: Fifty-one gastric biopsies were collected from patients with a presumptive diagnosis of <i>H. pylori</i>-induced gastritis at Hospital Carlos Alberto Seguín Escobedo in Arequipa, Peru, in March 2024. …”
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The influence of dietary choices: investigation of the relationship dietary inflammatory index and fetal growth restriction by Ayşe Gülçin Baştemur, İclal Sena Gezer, Burcu Kesikli, Atakan Tanaçan, Özgür Kara, Nuray Yazıhan, Dilek Şahin

“…Conclusion This study showed that a pro-inflammatory maternal diet increased dietary inflammatory index and increased maternal inflammatory markers, and this was more significant in fetuses with FGR than in normal weight fetuses.…”
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Healthcare under fire: quantifying the impact of violence on medical services in facilities supported by International Medical Corps in three prefectures of Central African Republi... by Natalya Kostandova, Jennifer OKeeffe, Audrey Mahieu, Blaise Bienvenu Ali, Christian Mulamba, Pierre Somsé, Odilon Guesset Bingou IV, Sebastien Dackpa, Gerard Mbonimpa, Thierry Fikiri, Larissa Fast, Leonard Rubenstein

“…Future research should build on these findings to provide more effective protection, mitigation, and recovery strategies for healthcare systems in conflict zones.…”
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The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…Besides, the combination of hematological indicators is more effective in diagnosing GC patients, especially for male patients (AUC=0.916, 95% CI: 0.901– 0.932, sensitivity: 84.98%, specificity: 84.29%). …”
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Association of Adenotonsillectomy with Vaso-occlusive Crisis Frequency in Sickle Cell Patients of Eastern Saudi Arabia: A Retrospective Study by Moath Alfaleh, Omar Alanzi, Ali Alaskari, Mohammed Alzamil, Hussain Al-Baharna

“…Vaso-occlusive Crisis (VOC), a defining symptom of SCD, is acute painful assaults caused by vaso-occlusion in the bone marrow. SCD is substantially more prevalent in some regions of Saudi Arabia than in others, with the Eastern Province having the highest incidence rates, followed by the Southern and Western provinces. …”
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Preoperative Talocalcaneal Distance and Subtalar Fusion are Not Associated with Worse Patient-Reported Outcomes in Progressive Collapsing Foot Deformity by Grace DiGiovanni BS, Agnes Jones MS, Seif El Masry, Jonathan T. Deland MD, Scott J. Ellis MD, Matthew S. Conti MD

“…Category: Hindfoot; Other Introduction/Purpose: As progressive collapsing foot deformity (PCFD) advances, narrowing between the lateral talar process and calcaneus at the angle of Gissane often occurs. This signifies more advanced peri-talar subluxation and may result in sinus tarsi impingement. …”
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Study of TRAF3IP3 for prognosis and immune infiltration in hepatocellular carcinoma by Xing Wang, Xin Gao, Airu Liu, Yan Qin, Zhi-Yu Ni, Xiao Lan Zhang

“…Results Analysis of public databases and immunohistochemical staining on 20 pairs of samples confirmed a decrease in TRAF3IP3 expression in HCC. …”
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Effect of Soft Rehabilitation Robot Gloves on Upper Limb and Hand Function of Stroke Patients：A Meta-Analysis by YU Tingting, SHEN Yuwei, WAN Guomeng, LI Jianan

“…Meta-analysis results showed that, compared with the control group, FMA-UE score [<italic>MD</italic>=8.05, 95% <italic>CI </italic>(7.01,9.09), <italic>Z</italic>=15.20, <italic>P</italic>&lt;0.000 01], MBI score [<italic>MD</italic>=9.91, 95% <italic>CI</italic> (2.65,17.17), <italic>Z</italic>=2.68, <italic>P</italic>=0.007], WMFT score [<italic>MD</italic>=8.39, 95% <italic>CI</italic> (6.99,9.78), <italic>Z</italic>=11.81，<italic>P</italic>&lt;0.000 01], grip strength [<italic>SMD</italic>=0.39, 95% <italic>CI</italic> (0.11,0.67), <italic>Z</italic>=2.75, <italic>P</italic>=0.006], and ARAT score [<italic>MD</italic>=11.18, 95% <italic>CI</italic> (9.10, 13.26), <italic>Z</italic>=10.53, <italic>P</italic>&lt;0.000 01] were significantly higher in the experimental group, but there was no significant difference in BBT score between two groups [<italic>MD</italic>=0.53, 95% <italic>CI</italic> (-1.47, 2.53), <italic>Z</italic>=0.52, <italic>P</italic>=0.60].ConclusionSRG can improve the upper limb and hand motor function and activities of daily living of stroke patients, but more large-sample and high-quality RCTs would be needed to further verify its efficacy.…”
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