Outcomes of Out‐of‐Hospital Cardiac Arrest at Centers With and Without On‐Site Coronary Angiography: A Nationwide Analysis by Shayan Ebrahimian, Troy Coaston, Amulya Vadlakonda, Joseph Hadaya, Sara Sakowitz, Ali Nsair, Radoslav Zinoviev, Boback Ziaeian, Eric H. Yang, Gregg C. Fonarow, Olcay Aksoy, Peyman Benharash

“…However, national data evaluating outcomes of OHCA admission to such centers remain limited. Methods Using the 2021 National Inpatient Sample, we identified all direct OHCA hospitalizations across US facilities. …”
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Effectiveness and Safety of DLBS3233 in Newly Diagnosed Type 2 Diabetes Mellitus: A 12-week Clinical Trial by Heri Nugroho, Nurmilawati Nurmilawati, Diana Novitasari, Lidia Rombeallo, Rambu Farah Effendi, Reski Reski, Intan Surayya, Nugroho Agung Daryanto, Solomon Putera, Raymond Rubianto Tjandrawinata

“…Further research with larger samples and more prolonged duration is warranted to comprehensively explore DLBS3233’s potential in T2DM management. …”
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Addressing the gap in preterm resuscitation practices in high-income and low-middle income countries: a multicenter survey of the Asian neonatal network collaboration by Rinawati Rohsiswatmo, Rizalya Dewi, Jennie Sutantio, Zubair Amin, Young-Ah Youn, Sae Yun Kim, Su Jin Cho, Yun Sil Chang, Satoshi Kusuda, Fuyu Miyake, Tetsuya Isayama

“…This study aimed to evaluate the resuscitation practices of high-risk infants in a large multi-country sample of healthcare facilities among HICs and LMICs in Asia under the AsianNeo Network.MethodsIn 2021, a customized 6-item online survey on resuscitation practices of infants born at <29 weeks gestation (or birth weight <1,200 g) was sent by the representative of each country's neonatal network to all the Neonatal Intensive Care Units (NICUs) participating in AsianNeo network. …”
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Tumor Invasion Distance Based on MRI Is a Novel Prognostic Indicator for I-IIIB Cervical Cancer Patients Treated with Radiotherapy by Linying Liu, Jie Lin, Anyang Li, Ning Xie, Jianfeng Zheng, Youping Xiao, Xuefen Lin, Shizhong Wu, Haijuan Yu, Yang Sun

“…The new risk stratification system based on TID could complement the 2018 FIGO staging system in identifying high-risk patients for more intense treatment and care. Further prospective research with larger samples is warranted to confirm the significance of TID for CC patients treated with RT.…”
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The plasma proteome reveals distinct signaling pathways associated with PR3-ANCA positive and MPO-ANCA positive vasculitis by Erik Hellbacher, Erik Hellbacher, Vincent van Hoef, Alina Johansson, Ann Knight, Ann Knight, Iva Gunnarsson, Iva Gunnarsson, Annette Bruchfeld, Annette Bruchfeld, Per Eriksson, Sophie Ohlsson, Solbritt Rantapää-Dahlqvist, Johanna Dahlqvist, Johanna Dahlqvist

“…This study aimed to identify key molecular signaling pathways activated in AAV and to elucidate molecular distinctions between AAV with proteinase 3 ANCA (PR3-AAV) and AAV with myeloperoxidase ANCA (MPO-AAV).MethodsPlasma samples from 41 cases with active PR3-AAV, 24 with active MPO-AAV and 138 population controls were analyzed for 185 proteins using proximity extension assay and Luminex. …”
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Serum Krebs von den Lungen-6 as a potential biomarker for early diagnosis of silicosis: a case-control study by Qiying Nong, Xuehua Zhu, Lin Zhong, Ying Li, Liang Yao, Zhiming Hu, Shan Wu, Ziping Zou, Cong Li, Zhifang Liu, Kengkeng Chen, Bizhu Zhang, Wei Wei, Yiru Qin, Yongshun Huang, Na Zhao, Lihua Xia

“…This study aims to evaluate the levels of Krebs von den Lungen-6 (KL-6) in patients with early-stage silicosis and explore its potential as a diagnostic biomarker. Methods Blood samples were collected from 40 stage I silicosis patients, 57 dust-exposed workers (DEWs), and 70 healthy controls (HCs). …”
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(Fear of) SARS-CoV-2 infection and psychological distress: a population-based cohort study in southern Switzerland by C. Sculco, B. Bano, G. Piumatti, R. Amati, C. Barbui, L. Crivelli, M. Purgato, E. Albanese

“…Results In our sample, 84.3% of the participants (mean age of 51.30 years, SD = ±.93) were seronegative at baseline. …”
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Comparison of Patellar Tracking Following Kinematic Alignment Versus Mechanical Alignment Total Knee Arthroplasty via the Mini‐Subvastus Approach by Bochen Sun, Yiyang Xu, Guiguan Wang, Long Chen, Fenqi Luo, Guoyu Yu, Yuan Lin, Jie Xu

“…In our opinion, KA‐TKA via the mini‐subvastus approach may be a more suitable surgical option.…”
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Dynamic circulating tumor DNA indicates pathological benefits of additional neoadjuvant chemoimmunotherapy courses for locally advanced non-small-cell lung cancer patients by Dong Lin, Liang Wu, Pei Wang, Xiaolong Li, Xiaolan Wang, Yiran Cai, Kangli Xiong, Xi Chen, Fu Yang, Wei Huang, Xing Wang, Jiang Fan

“…This study introduced minimal residual disease (MRD) based on circulating tumor DNA (ctDNA), and investigated the association between ctDNA-MRD and NCI cycles and pathological response.Materials and methodsThis study was based on a phase III trial (NCT05157776). …”
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Agreement of glomerular filtration rate estimation equations for chemotherapy dosing in cancer patients at a tertiary referral hospital in Sub-Saharan Africa. by Wubshet Jote Tolossa, Tigist Workneh Leulseged, Abdu Adem, Feyissa Challa, Tirumebet Mezgebu, Ruth S Aytehgeza, Nebiat Adane Mera, Kalsidagn Girma Asfaw, Momina M Ahmed, Kebede H Begna

“…The Cockcroft-Gault formula remains the most widely used equation in cancer patients, despite the availability of more precise kidney function estimation equations. …”
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Effects of a novel differential diagnosis aid for managing patients with unexplained fatigue in primary care: a prospective randomized, controlled, open and multicenter study in pr... by Roland von Känel, Stefan Neuner-Jehle, Reto W. Kressig, Idris Guessous, Pierre Alexandre Krayenbühl, Lukas Zimmerli, Anne Angelilo-Scherer, Thomas Keller, Caroline Elzner, Karl Pauls, Neige Morin, Edouard Battegay

“…At the time of registration, two protocol deviations occurred that are explicitly addressed in the Methods section of this manuscript. Because of the low sample size, we statistically compared “patients” instead of “comparing patients nested in doctors” (the latter was performed as an additional analysis). …”
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GPR87 promotes invasion and migration through the RHO/ROCK pathway in non-small cell lung cancer by LIU Chenxi, HAN Lin, YANG Yi, ZHOU Han, LIU Yayun, SHENG Deqiao

“…Objective·To explore the role and molecular mechanism of GPR87 in regulating the invasion and migration of non-small cell lung cancer (NSCLC).Methods·Bioinformatics methods, including GEO, UALCAN, KM Plotter and other public database analysis platforms, were used to screen candidate genes related to NSCLC invasion and predict their clinical relevance to NSCLC. …”
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Predictors of Toxoplasma gondii IgG Seropositivity and Cranial Ultrasound Patterns among Children with Hydrocephalus by Sofia Ottaru, Mariam M. Mirambo, Rogatus Kabyemera, Benson R. Kidenya, Mwanaisha Seugendo, Delfina R. Msanga, Patrick Ngoya, Domenica Morona, Stephen E. Mshana

“…Obstructive hydrocephalus was significantly more common among T. gondii-seronegative infants compared to IgG-seropositive infants (31.3% [30/96] vs. 13.8% [4/29]; p=0.049). …”
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Comparison of Surface Roughness of Class V Cavity Preparation using Diamond Abrasive Point and Ultrasonic Tip and Measurement of Shear Bond Strength after Restoration with Composit... by Abhijit Ghosh, Priti D Desai, Ipsita Maity, Paromita Mazumdar

“…Tooth preparation traditionally uses diamond abrasive points and tungsten carbide burs for micromechanical adhesion. Newer methods, like ultrasonic tips, offer a more conservative approach, but limited research has compared their effects on bond strength, particularly in cervical cavity restorations with nanohybrid composites. …”
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The impact of a school-based physical activity program on children's movement behaviors, aerobic fitness and motor competence: a follow up study by Moreno Bloch, Rita Cordovil, Rita Cordovil, Luís P. Rodrigues, Luís P. Rodrigues, Clarice Martins, Maria L. Braga, Susana Vale, Susana Vale, Rui Proença, João Brito, João Brito, José Guilherme, José Guilherme, Carlos Neto, André Seabra, André Seabra, Júlio A. Costa

“…Due to school changes and parental noncompliance, the sample decreased from 38 to 23 participants (EG; n = 13; CG; n = 10), a 39% dropout rate.ResultsOne year post-intervention, the EG spent more time in moderate-to-vigorous PA (MVPA; + 41 min/day), less time in SED (−234 min/day), slept longer (+103 min/night), covered greater distances in the YYIR1C (+174 m), and achieved higher MC scores (+19% on the MCA battery test) compared to the CG. …”
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Spatial distribution of Culex mosquitoes across England and Wales, July 2023 by Emma Widlake, Roksana Wilson, Jack Pilgrim, Alexander G. C. Vaux, Jolanta Tanianis-Hughes, Amirah Haziqah-Rashid, Ken Sherlock, Agata Delnicka, Amelia Simpson, Anthony J. Abbott, Colin J. Johnston, Jude Martin, Kendall Barlow, Eloise Aliski, Saffron Shiels, Sara Gandy, Sarah M. Biddlecombe, Joanna de Klerk, Luigi Sedda, Jolyon M. Medlock, Matthew Baylis, Marcus S. C. Blagrove

“…Here, we describe a comprehensive nationwide field surveillance study conducted during July 2023 to map the distribution of the WNV and USUV competent vectors: Culex pipiens biotype pipiens, Culex pipiens biotype molestus and Culex torrentium, across England and Wales. Methods Mosquitoes were sampled for 3 trap nights (3TN) at 200 sites in rural, urban and suburban settings, selected using a lattice plus close pairs surveillance design. …”
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Microbial community structure and resistome dynamics on elevator buttons in response to surface disinfection practices by Shanshan Ye, Shanshan Ye, Shifu Peng, Xiaolei Wang, Xiaolei Wang, Jingjing Fan, Jingjing Fan, Chenxue Zhu, Liye Huang, Ying Huang, Keping Cheng, Tingting Ni, Yuqing Qian, Xiaosong Wu, Xiaosong Wu, Xiaosong Wu, Xiaosong Wu, Yan Xu, Yan Xu, Yan Xu, Yan Xu

“…Both α-diversity (within-sample diversity) and β-diversity (between-sample diversity) were lower and more distinct in quarantine hotels compared to the other environments. …”
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Barriers and facilitators to patient utilization of noncommunicable disease services in primary healthcare facilities in Nepal: a qualitative study by Sushmita Mali, Elizabeth C. Rhodes, Chandani Singh Nakarmi, Soniya Shrestha, Aarati Dhakal, Alina Bharati, Anupama Bishwokarma, Asmita Adhikari, Bikram Poudel, Binuka Kulung Rai, Sangita Manandhar, Surakshya KC, Dinesh Timalsena, Sashi Silwal, Meghnath Dhimal, Phanindra Prasad Baral, Felix Teufel, Sanju Bhattarai, Donna Spiegelman, Archana Shrestha

“…This study explored barriers and facilitators to patient utilization of NCD services at primary healthcare facilities in Nepal. Methods We conducted a qualitative study with a 35 purposive sample of patients living with one or more NCDs (hypertension, diabetes, chronic obstructive pulmonary disease (COPD/ asthma) who sought healthcare at primary healthcare facilities in 14 randomly selected districts in seven provinces in Nepal that implemented PEN. …”
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Effectiveness and safety of perampanel for pediatric patients with epilepsy: A real‐world study from China by Xiaohui Wang, Taoyun Ji, Maomao Liu, Xiaofei Wang, Zhixian Yang, Sanmei Wang, Liping Zou, Jiong Qin, Xiaotun Ren, Liankun Ren, Liri Jin, Jie Shi, Dantao Peng, Kui Chen, Jindong Dai, Nan Zhang, Jun Wang, Tianyu Song, Fang Fang, Yuehua Zhang, Qun Wang

“…Objective To evaluate the effectiveness, retention, and safety of PER in the treatment of children and adolescents with epilepsy in China. Methods This was a multicenter, prospective, observational study. …”
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Probiotics mitigate stress and inflammation in malnourished adults via gut microbiota modulation: a randomized controlled trial by Maryam Ahmadi-Khorram, Maryam Ahmadi-Khorram, Alireza Hatami, Alireza Hatami, Parastoo Asghari, Parastoo Asghari, Ali Jafarzadeh Esfehani, Asma Afshari, Fateme Javdan, Fateme Javdan, Mohsen Nematy, Mohsen Nematy

“…Within-group analysis revealed improvements in anthropometric measures and inflammatory markers in both groups (p < 0.05), but stress reduction was more pronounced in the probiotic group (34% vs. 9.3%, p = 0.017). …”
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