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  1. 18181
  2. 18182

    Serum IL-23 levels reflect a myeloid inflammatory signature and predict the response to apremilast in patients with psoriatic arthritis by Maria De Santis, Maria De Santis, Antonio Tonutti, Antonio Tonutti, Natasa Isailovic, Francesca Motta, Francesca Motta, Radu Marian Rivara, Rita Ragusa, Giacomo M. Guidelli, Marta Caprioli, Angela Ceribelli, Angela Ceribelli, Daniela Renna, Nicoletta Luciano, Nicoletta Luciano, Carlo Selmi, Carlo Selmi

    Published 2024-12-01
    “…BackgroundThe phosphodiesterase 4 (PDE4) inhibitor apremilast downregulates the production of IL-23 and other pro-inflammatory cytokines involved in the pathogenesis of psoriatic arthritis (PsA).AimTo investigate the effects of apremilast on the production of cytokines by peripheral blood monocyte-derived macrophages, innate-like lymphocyte cells (ILCs), mucosal-associated invariant T (MAIT) cells, γδ T cells, natural killer (NK) cells, and NKT-like cells from patients with PsA manifesting different clinical responses to the treatment.MethodsPeripheral blood samples were obtained from patients with PsA at baseline and after 1 and 4 months of apremilast therapy (n = 23) and 20 controls with osteoarthritis. …”
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  3. 18183

    Assessing mutation-clinical correlations and treatment outcomes in Vietnamese non-small cell lung cancer patients by Hoang-Bac Nguyen, Bang-Suong Nguyen-Thi, Huu-Huy Nguyen, Minh-Khoi Le, Quoc-Trung Lam, Tuan-Anh Nguyen

    Published 2025-07-01
    “…Pre-treatment samples were analyzed via massively parallel sequencing, and survival analysis assessed the impact of EGFR/KRAS mutations on survival and TKI response. …”
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  4. 18184
  5. 18185

    Bone mineral density in comparison to anthropometric parameters and level of gross motor function in children with cerebral palsy by Zvekić-Svorcan Jelena, Stojšić Mirjana, Krasnik Rastislava, Nenadov Nataša, Demeši-Drljan Čila, Mikov Aleksandra, Radovanov Maja

    Published 2019-01-01
    “…Children with the CP Level IV on the GMFCS-E&R had a significantly lower bone density (spinal Z-score -1.90 SD; hip Z-score -3.40 SD), with the reduction even more pronounced at level V (spinal Z-score -3.80 SD; hip Z-score -2.30 SD). …”
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  6. 18186

    EXPERIMENTAL STUDY OF FURCATION AREA AND PROSPECTS OF ITS COMPLEX TREATMENT by Yu.V. Sidash, O.P. Kostyrenko, V.N. Petrushanko

    Published 2021-06-01
    “…A significant percentage of periodontitis occurs in the area of furcations of multi-rooted teeth, sometimes alone, but more often as combined with apical periodontitis. …”
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  7. 18187

    Identificación de personas a través del cotejo de radiografías panorámicas y periapicales. Comparación de características observadas en 30 pacientes Identification of people throug... by Clarisa Yanina Gómez, Pamela Borgo Cosentino, Alan Diego Briem Stamm

    Published 2025-03-01
    “…A comparison was conducted between AM and PM samples, in all cases confronting a panoramic radiograph with one or more periapical radiographs. …”
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  8. 18188

    Identifying bellwether sewershed sites for sustainable disease surveillance in Bengaluru, India: a longitudinal studyResearch in context by Rebecca Fern Daniel, Subash K. Kannan, Namrta Daroch, Sutharsan Ganesan, Farhina Mozaffer, Vishwanath Srikantaiah, Lingadahalli Subrahmanya Shashidhara, Rakesh Mishra, Farah Ishtiaq

    Published 2025-08-01
    “…Summary: Background: Throughout the COVID-19 pandemic, wastewater surveillance emerged as an important tool as an important tool by providing data that are more representative of the population than case reporting, which is often biased towards individuals with health-seeking behaviour or access to healthcare. …”
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  9. 18189

    A pilot study exploring long-read nanopore metagenomics sequencing for heteroresistance detection in clinical specimens by Miss Siphiwe Matukane, Miss Khensani Hattingh, Dr Kristien Nel Van Zyl, Dr Mae Newton-Foot, Prof Andrew Whitelaw

    Published 2025-03-01
    “…This study explored ONT sequencing and compared two analysis pipelines for detecting resistant bacterial subpopulations. Methods: Confirmed culture-negative, antibiotic-free, and E. coli DNA-free urine samples were pooled and spiked with well-characterised resistant and susceptible E. coli isolates to simulate 10%, 5%, and 2% heteroresistance. …”
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  10. 18190

    Sialyltransferase gene signature as a predictor of prognosis and therapeutic response in kidney renal clear cell carcinoma by Huiyu Liu, Changwei Zhou, Zaichun Yan, Hairong Yang, Yun Zhao, Rui Tian, Xuejun Bo, Leizuo Zhao, Wei Ren

    Published 2025-05-01
    “…This study aimed to develop a prognostic model based on sialyltransferase-related genes (SRGs) to predict the prognosis and treatment response of patients with KIRC. Methods We utilized RNA-Seq data of KIRC from The Cancer Genome Atlas (TCGA) database, selecting samples with survival data and clinical outcomes. …”
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  11. 18191

    Contamination risk and drug resistance analysis of Klebsiella pneumoniae in a medical institution in Minghang District, Shanghai, 2021‒2023 by ZHANG Sijia, ZHANG Xing, TIAN Liang, ZHOU Yibin, WEN Xiaosa, WANG Jing, XU Zhiyin, WU Min

    Published 2025-04-01
    “…ObjectiveTo investigate the contamination status, transmission risk and drug resistance of Klebsiella pneumoniae (KP) on the object surfaces in the surrounding environment of hospitalized patients infected with carbapenem-resistant Klebsiella pneumoniae (CRKP) , so as to provide a scientific guidance for the prevention and control of healthcare-associated infection.MethodsSamples from the surfaces of objects in the surrounding environment of CRKP infected patients living in the intensive care unit (ICU) and hand specimens from healthcare workers were collected for KP isolation and identification, as well as drug susceptible test in a medical institution located in Minhang District, Shanghai from 2021 to 2023. …”
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  12. 18192

    Comparison of Biocompatibility of 3D-Printed Ceramic and Titanium in Micropig Ankle Hemiarthroplasty by Si-Wook Lee, Donghyun Lee, Junsik Kim, Sanghyun An, Chul-Hyun Park, Jung-Min Lee, Chang-Jin Yon, Yu-Ran Heo

    Published 2024-11-01
    “…In micro-CT analysis, the adhesive tissue score of the ceramic artificial sample was better than that of the titanium sample (average threshold = 3027.18 ± 405.92). …”
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  13. 18193

    Study on the Compatibility of C<sub>6</sub>F<sub>12</sub>O Gas Mixture with EPDM by Shuangshuang TIAN, Benli LIU, Guangyu DENG, Xiaoxing ZHANG, Huihui LI, Weihao LIU, Hui CHEN

    Published 2024-09-01
    “…The reaction between the C<sub>6</sub>F<sub>12</sub>O/CO<sub>2</sub> mixture and EPDM was more intensive after adding O<sub>2</sub>, leading to a significant decrease in the mechanical properties of EPDM. …”
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  14. 18194

    Microplastic analysis in soils: A comparative assessment by Stoyana Peneva, Quynh Nhu Phan Le, Davi R. Munhoz, Olivia Wrigley, Flora Wille, Heidi Doose, Crispin Halsall, Paula Harkes, Michael Sander, Melanie Braun, Wulf Amelung

    Published 2025-01-01
    “…Raman spectroscopy was most sensitive to soil organic matter residues, requiring more sophisticated sample pretreatment. Fluorescence staining with subsequent Fluorescence microscopy detection effectively recovered most small-sized LDPE-MiP but missed 56–93 % of small PBAT/ PLA particles. …”
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  15. 18195

    Clinical and Epidemiological Characteristics of Leptospirosis in the Gomel Region by O. L. Tumash, L. P. Mamchits

    Published 2024-09-01
    “…Cterohaemorrhagiae and L. Pomona were detected more often, in total, these pathogens accounted for 46.5% of positive samples. …”
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  16. 18196

    Differences in the pathological, transcriptomic, and prognostic implications of lymphoid structures between primary and metastatic cutaneous melanomas by Jin Xu, Andrew Knight, Jonathan Nguyen, Hong Wang, Walter J Storkus, Cindy Sander, John M Kirkwood, Jiqiang Yao, Xiaofei Song, Jane Messina, James J Mulé, Lilit Karapetyan, Carlos Moran-Segura, Aofei Li, Marion Joy, Sabrina Bruno, Hassan M Abushukair, Danielle Vargas De Stefano, Ayah N Al-Bzour, Caroline Layding

    Published 2024-11-01
    “…In this study, we examined characteristics and the prognostic utility of LA and TLS status in histological samples from patients with melanoma.Methods We assessed The Cancer Genomic Atlas-skin cutaneous melanoma digital slides and melanoma specimens from the University of Pittsburgh for the presence of LA and TLS using H&amp;E staining, multiplex immunofluorescence (mIF) and transcriptomic analyses. …”
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    Effectiveness and Safety of DLBS3233 in Newly Diagnosed Type 2 Diabetes Mellitus: A 12-week Clinical Trial by Heri Nugroho, Nurmilawati Nurmilawati, Diana Novitasari, Lidia Rombeallo, Rambu Farah Effendi, Reski Reski, Intan Surayya, Nugroho Agung Daryanto, Solomon Putera, Raymond Rubianto Tjandrawinata

    Published 2024-07-01
    “…Further research with larger samples and more prolonged duration is warranted to comprehensively explore DLBS3233’s potential in T2DM management.…”
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