OM‐85, a Bacterial Lysate, Reduces Pulmonary Nodule Malignant Probability: A Retrospective Study by Mengting Sun, Yuqing Ni, Xueling Wu, Hao Tian, Yijun Song, Yinzhou Feng, Yunxin Guo, Yong Zhang, Jun Yin, Charles A. Powell, Chunxue Bai, Yuanlin Song, Dawei Yang

“…The effects of OM‐85 treatment were more pronounced in older patients (> 65‐year‐old) (p = 0.029) and those with longer follow‐up cycles (> 200 days) (p = 0.011). …”
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Fire ant-venom anaphylaxis prevalence in the general population and patients with systemic mastocytosis by Jeremy C. McMurray, Jeremy C. McMurray, Brandon J. Schornack, Brandon J. Schornack, Karla E. Adams, Robert L. McCoy, Amanda K. Marshall, Janet A. Brunader, Irina Maric, Dean D. Metcalfe, Nathan A. Boggs, Nathan A. Boggs

“…Chart review of a random sample of 150 patients linked to a HVA ICD-10 code was performed to determine the percent of patients with Hymenoptera-venom anaphylaxis. …”
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Surveillance towards preventing paediatric incidence of respiratory syncytial virus attributable respiratory tract infection in primary and secondary/tertiary healthcare settings i... by Adam Finn, David Lewis, James Dodd, Matthew Taylor, Maia Lesosky, Paul Stephen McNamara, Helen Hill, Emma Carter, Kelly Davies, Fred Fyles, Carla Solorzano, Daniela M Ferreira, Gregory Duncan, Lauren McLellan, Mathieu Bangert, Natalya Vassilouthis, Andrea M Collins

“…Such data will contribute to informing public health strategies to prevent RSV-associated infection, including use of preventative medications.Methods and analysis Parents/carers of children <3 years of age with RTI symptoms will consent for a respiratory sample (nasal swab) to be taken. …”
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Assessing Torquetenovirus (TTV) as a Biomarker for Immune Responses to SARS-CoV-2 mRNA Vaccines in People Living with HIV and Healthy Individuals by Claudia Minosse, Pietro Giorgio Spezia, Valentina Mazzotta, Giulia Matusali, Silvia Meschi, Francesca Colavita, Davide Mariotti, Stefania Notari, Alessandra Vergori, Daniele Focosi, Enrico Girardi, Andrea Antinori, Fabrizio Maggi

“…This study aimed to evaluate whether pre-vaccine TTV VL could predict humoral and cellular immune responses to SARS-CoV-2 mRNA vaccines in people living with HIV (PLWH) and healthy individuals (HP). <b>Methods</b>: TTV VL was measured via real-time PCR in serum samples collected before the second and third doses of mRNA vaccines in 93 PLWH and 48 HP (second dose) and 255 PLWH and 48 HP (third dose). …”
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The Synergistic Effect of Intradialytic Concurrent Training and Melatonin Supplementation on Oxidative Stress and Inflammation in Hemodialysis Patients: A Double-Blind Randomized C... by Houssem Marzougui, Imen Ben Dhia, Ines Mezghani, Rami Maaloul, Salma Toumi, Khawla Kammoun, Mohamed Nejib Chaabouni, Fatma Ayadi, Mohamed Ben Hmida, Mouna Turki, Omar Hammouda

“…Conclusion: Concurrent training combined with MEL supplementation enhances oxidant–antioxidant balance and reduces inflammation in HD patients more effectively than intradialytic concurrent training alone.…”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…The aim was to study the association between e-cigarette use and, changes in smoking status and changes in respiratory symptoms. Methods A prospective, population-based study of random samples of the population (age 16–69 years) was performed within The Obstructive Lung Disease in Northern Sweden (OLIN) study and West Sweden Asthma Study (WSAS). …”
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Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma by Gao-Sheng Yao, Jun-Shang Dai, Jun-Shang Dai, Liang-Min Fu, Liang-Min Fu, Juan Lin, Zhi-Ping Tan, Lei Dai, Wei Chen, Jun-Hang Luo, Jun-Hang Luo, Jin-Huan Wei

“…Specifically, Nivolumab is more effective for patients with higher scores.ConclusionThe necroptosis-related signature we constructed can accurately predict the prognosis of ccRCC patients and further provide clues for targeted, individualized therapy.…”
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Integrative genomic and single-cell framework identifies druggable targets for colorectal cancer precision therapy by Yanggang Hong, Yanggang Hong, Jiajun Li, Jiajun Li, Nuo Xu, Wanyi Shu, Feng Chen, Yuze Mi, Haigang Geng, Haigang Geng, Qian Li

“…These findings open avenues for advancing precision oncology and drug repurposing strategies in CRC treatment, contributing to the development of more effective and personalized therapeutic approaches.…”
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Integrating TSPO-PET imaging with metabolomics for enhanced prognostic accuracy in multiple sclerosis by Jens Kuhle, Laura Airas, Daniel C Anthony, David Leppert, Eline Willemse, Fay Probert, Johanna Oechtering, Markus Matilainen, Marcus Sucksdorff, Daniel E Radford-Smith, Abi G Yates, Tereza Kacerova, Marjo Nylund, Aleksandra Maleska Maceski

“…This study investigates whether combining TSPO imaging with metabolomics enhances predictive accuracy in a similar setting.Methods Blood samples were collected from 87 MS patients undergoing PET imaging with the TSPO-binding radioligand 11C-PK11195 in Finland. …”
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Association of body mass index and outcomes in surgical and transcatheter aortic valve replacement by Bennet S. Cho, MD, Troy N. Coaston, BS, Amulya Vadlakonda, BS, Sara Sakowitz, MPH, MS, Syed Shaheer Ali, Esteban Aguayo, MD, Peyman Benharash, MD

“…This study assessed the nuanced relationship between BMI and clinical outcomes in a nationally representative cohort undergoing aortic valve replacement. Methods: Adult (≥18 years) admissions for elective SAVR or TAVR from the 2016–2021 National Inpatient Sample were analyzed. …”
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The features of Tat protein of human immunodeficiency virus type 1 (Retroviridae: <i>Lentivirus: Lentivirus humimdef1</i>) non-A6 variants, characteristic for the Russian Federatio... by Anna I. Kuznetsova, Anastasiia A. Antonova, Aleksey V. Lebedev, Ekaterina N. Ozhmegova, Anastasia V. Shlykova, Ilya A. Lapovok, Oxana V. Galzitskaya

“…A limitation of this study is the small sample of sequences.…”
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Exploring the role of ELOVLs family in lung adenocarcinoma based on bioinformatic analysis and experimental validation by Zihan Wang, Wenjing Cui, Long Liang, Jingge Qu, Yuqiang Pei, Danyang Li, Ying Luo, Yue Zhang, Yifan Qiu, Yongchang Sun

“…The aim of our study is to explore whether there are genes related to the pathogenesis of LUAD in the ELOVLs family, and even to guide clinical medication and potential prognostic indicators. Methods Gene expression profiling interactive analysis (GEPIA), human protein atlas (HPA), cBioPortal, Kaplan–Meier (KM) plotter, single-sample Gene Set Enrichment Analysis (ssGSEA) algorithm and SubMap algorithms were utilized to analyze the role of ELOVLs in the LUAD. …”
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Effect of charcoal-containing toothpastes on roughness and color stability of bulk-fill resin composites by Waldemir Francisco Vieira Junior, Rafaella Queiróz Costa, Leonardo Santos Barros, Mariana Mayume Mori, Cecilia Pedroso Turssi, Fabiana Mantovani Gomes França, Núbia Inocencya Pavesi Pini, Roberta Tarkany Basting

“… Objective: To evaluate the effects of different commercially available charcoal-based toothpastes (CBTs) on the roughness and color of bulk-fill resin composites (RCs). Materials and Methods: Disc-shaped samples (6 × 2 mm) were made with nanofilled (NF) bulk-fill (Filtek One, 3M Oral Care) or nanohybrid (NH) bulk-fill (Aura, SDI) RCs. …”
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Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer by Miao Ao, You Wu, Kunyu Wang, Haixia Luo, Wei Mao, Anqi Zhao, Xiaomeng Su, Yan Song, Bin Li

“…GO and KEGG analysis confirmed these genes were enriched in the generation of precursor metabolites and energy. It illustrated more lymphocyte infiltration in the high MS group than low MS group. …”
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Garlic Extracts Nanoliposome as an Enhancer of Bioavailability of ABA and Thiamine Content and as an Antifungal Agent Against <i>Fusarium oxysporum</i> f. sp. <i>pisi</i> Infecting... by Barbara Kutasy, Géza Hegedűs, Márta Kiniczky, József Péter Pallos, Ágnes Nagy, István Pócsi, Klaudia Pákozdi, Máté Kállai, Csaba Weingart, Katalin Andor, Bettina Kovács, Eszter Virág

“…However, effective disease management strategies, particularly the implementation of biological control methods, offer promising approaches for mitigating infection severity and limiting pathogen spread. …”
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Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece by María Fernanda Skowronek, Santiago Pietroroia, Gabriel de Cola, Mauricio Ramos, Diego Silvera, Gabriela Casanova, Federico Lecumberry, Adriana Cassina, Adriana Cassina, Rossana Sapiro, Rossana Sapiro

“…Ultrastructural analysis further revealed that mitochondria in sperm from infertile men were significantly larger and more irregular in shape compared to those from fertile men. …”
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Kinetics of Neutralizing Antibody Response Underscores Clinical COVID-19 Progression by Qing Lei, Hongyan Hou, Caizheng Yu, Yandi Zhang, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Zongjie Yao, Hui Fu, Ziyong Sun, Feng Wang, Xionglin Fan

“…The role of nAb during clinical progression of coronavirus disease 2019 (COVID-19) remains little known. Methods. 123 COVID-19 patients during hospitalization in Tongji Hospital were involved in this retrospective study. …”
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High Neutrophil Alkaline Phosphatase Activity in Adult-Onset Still’s Disease by Nana Ding, Haiye Ren, Jialin Teng, Xiaobing Cheng, Junna Ye, Yutong Su, Hui Shi, Qiongyi Hu, Yue Sun, Jianfen Meng, Huihui Chi, Zhuochao Zhou, Jinchao Jia, Chengde Yang, Hong-Lei Liu

“…Blood samples were collected and smears were prepared, stained, and analyzed to calculate the NAP score. …”
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The relationship between immigrant status, cultural/racial background, and hypothyroidism among middle-aged and older Canadians: An analysis of Canadian Longitudinal Study on Aging... by ZhiDi Deng, PharmD, Karen M Davison, PhD RD, Michelle Cartier, MA, Andie MacNeil, MA MSW, Esme Fuller-Thomson, PhD

“…Non-pharmacologic nutrition-based interventions may be helpful in the prevention or management of hypothyroidism, however more research is needed.…”
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Changes in stigma and population mental health literacy before and after the Covid-19 pandemic: Analyses of repeated cross-sectional studies by Petr Winkler, Benjamin Kunc, Zoe Guerrero, Pavel Mohr, Georg Schomerus, Karolína Mladá

“…We aimed to compare levels of mental health related stigma among the Czech general adult population before and after the Covid-19 pandemic, as well as recognition of own mental health problems, among those members of the general population who screened positively for mental disorders. Methods: We conducted a comprehensive analysis of multiple almost identically designed cross-sectional surveys carried out on representative samples of the non-institutionalized adult population in Czechia in 2017, 2019, and 2022. …”
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