Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…Overall, this novel assay offers a simple, fast, cost-effective, and, likely, more clinically relevant alternative for diagnosing FHAAs in at-risk populations.…”
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COVID-19’s Influence on Ocular Emergency Visits at a Tertiary Referral Center and Its Relationship to Emergency Indications by the American Academy of Ophthalmology by Sharon Armarnik, Michael Kinori, Amir Abd Elkader, Sharon Blum Meirovitch, Noa Kapelushnik, Shiran Madgar, Hila Goldberg, Oded Sagiv, Tamara Wygnanski-Jaffe, Ayelet Priel

“…To examine the trends of ocular emergency admissions during the COVID-19 pandemic at a tertiary care center. Methods. The study’s sample consisted of all patients who were seen in the ophthalmic emergency room (OER) between March 15 and April 15, 2020 (during the COVID-19 pandemic) and in the same time frame of the previous year. …”
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Prenatal thallium exposure and child neurodevelopment at 2 years: a birth cohort study in China by Mingyang Wu, Yanling Shu, Lulu Song, Youjie Wang

“…Objective: To investigate the trimester-specific associations of maternal thallium exposure with early childhood neurodevelopment. Methods: A total of 423 mother-child pairs, with trimester-specific urinary samples, were followed up until the children reached 2 years of age. …”
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Prevalence of Extended-Spectrum β-Lactamase-Producing <i>Escherichia coli</i>, <i>Klebsiella pneumoniae</i> and <i>Enterobacter cloacae</i> in Wastewater Effluent in Blantyre, Mala... by Edna Ibrahim, Charity Mkwanda, Edward Masoambeta, Luigia Scudeller, Tomislav Kostyanev, Hussein H. Twabi, Yohane K. Diness, Jobiba Chinkhumba, Janelisa Musaya, Rajhab S. Mkakosya, Surbhi Malhotra-Kumar, Chantal M. Morel, Save Kumwenda, Chisomo L. Msefula

“…<b>Results</b>: A total of 288 samples were collected between April 2023 and March 2024, and 97.6% (281/288) yielded one or more presumptive ESBL isolates. …”
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Highly antimicrobial-resistant Nontyphoidal Salmonella from retail meats and clinical impact in children, Taiwan by Yi-Jung Chang, Mi-Chi Chen, Ye Feng, Lin-Hui Su, Hsin-Chieh Li, Hsin-Ping Yang, Min-Jia Yu, Chyi-Liang Chen, Cheng-Hsun Chiu

“…Background: The epidemiology of nontyphoidal Salmonella (NTS) resistant to ciprofloxacin or ceftriaxone and its impact on patients’ clinical course are rarely reported. Methods: Children with culture-proven salmonellosis treated in a medical center in northern Taiwan in 2017 were enrolled. …”
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Suicidal risk among adolescent psychiatric inpatients: the role of insomnia, depression, and social-personal factors by Valentina Baldini, Martina Gnazzo, Martina Maragno, Rebecca Biagetti, Camilla Stefanini, Francesco Canulli, Giorgia Varallo, Cristina Donati, Giovanni Neri, Andrea Fiorillo, Giuseppe Plazzi

“…This study investigates the interplay between these factors in a sample of adolescent psychiatric inpatients in Italy, with a particular focus on their association with suicide attempts. …”
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Prevalence and predictors of chronic disease among rural and medically underserved populations using smokeless tobacco by Elaine Sang, Elaine Sang, Susan Silva, Sarah Grenon, Courtney Swinkels, Shamatree Shakya, Salsa Deshmukh, Laura J. Fish, Laura J. Fish, Mariana Da Costa, Leigh Ann Simmons, Herbert H. Severson, Kathryn I. Pollak, Kathryn I. Pollak, Devon Noonan, Devon Noonan

“…Inequities in use exist as rural and other medically underserved populations use SLT more than that of the general population. Our study examined prevalence of chronic disease and identified associated risk factors among rural and medically underserved populations using smokeless tobacco.MethodsWe conducted a cross-sectional analysis of baseline data (N = 532) from a clinical trial promoting SLT cessation among adults living in rural and/or medically underserved areas and examined the rates of eight chronic diseases: cancer, lung disease, heart disease, stroke, mental health conditions, diabetes, arthritis/orthopedic conditions, and hypertension. …”
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Employment and the youth mental health crisis in Canada: distinct influences across phases of the school-to-work transition by Véronique Dupéré, Véronique Dupéré, Véronique Dupéré, Mathieu Caron-Diotte, Mathieu Caron-Diotte, Nancy Beauregard, Nancy Beauregard, Clémentine Courdi, Clémentine Courdi, Jiseul Sophia Ahn, Jiseul Sophia Ahn, Elizabeth Olivier, Elizabeth Olivier, Kristel Tardif-Grenier, Kristel Tardif-Grenier, David Litalien

“…This study addresses this gap, considering how the role of employment might vary depending on young adults’ educational status and level.MethodsA representative sample of 6,700 young adults (18–30 y.o.) drawn from Statistics Canada’s Longitudinal and International Study of Adults (2012–2020) was used to examine links between working hours and employment in a study-related job and mental health (life satisfaction, global mental health, psychological distress), beyond prior mental health and background characteristics. …”
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Loss of OBSCN expression promotes bladder cancer progression but enhances the efficacy of PD-L1 inhibitors by Tao Wang, Tuanjie Guo, Juanjuan Sun, Xinyue Zang, Lei Dong, Jian Zhang, Siteng Chen, Guihua Chen, Sicong Ma, Xinyu Zhai, Chuanmin Chu, Chaofu Wang, Xiang Wang, Dongliang Xu, Mingyue Tan

“…IHC and Western blot assay identified that BLCA samples with low OBSCN expression had more CD8+ T-cell infiltration and higher PD-L1 expression. …”
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Circulation of <i>Mycobacterium tuberculosis</i> strains of the Beijing Central Asian Outbreak genotype in the Kemerovo region — Kuzbass in 2018–2022 by Svetlana N. Zhdanova, Anna A. Vyazovaya, Irina B. Lebedeva, Vyacheslav V. Sinkov, Ilya G. Kondratov, Yakov Sh. Schwartz, Lyubov V. Rychkova, Elena B. Brusina, Igor V. Mokrousov, Oleg B. Ogarkov

“…The proportion of Beijing CAO was 12.6% of the total sample; this subtype was significantly more often detected among HIV/TB (20.6%) than in HIV-negative TB patients (9.1%; p = 0.005). …”
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Targeted detection of endogenous LINE-1 proteins and ORF2p interactions by Mathias I. Nielsen, Justina C. Wolters, Omar G. Rosas Bringas, Hua Jiang, Luciano H. Di Stefano, Mehrnoosh Oghbaie, Samira Hozeifi, Mats J. Nitert, Alienke van Pijkeren, Marieke Smit, Lars ter Morsche, Apostolos Mourtzinos, Vikram Deshpande, Martin S. Taylor, Brian T. Chait, John LaCava

“…The translation product of ORF1 (ORF1p) has been robustly detected by immunoassays and shotgun mass spectrometry (MS). Yet, more sensitive detection methods would enhance the use of ORF1p as a clinical biomarker. …”
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Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Furthermore, the MYC inhibitor demonstrated more sensitivity for the major nodules than minor nodules. …”
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Relationship between DLK-1 levels in blood serum and survival of patients with glioblastoma by A. I. Ryabova, V. A. Novikov, L. V. Spirina, A. B. Dospan, E. L. Choynzonov, O. V. Gribova, O. A. Muzenik, V. A. Syrkashev, S. A. Glushchenko, S. A. Tabakaev, I. N. Udintseva

“…Several studies have shown that the increased expression of delta–like noncanonical Notch ligand 1 (DLK-1) is associated with more aggressive tumor characteristics in patients with glioblastoma. …”
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A comprehensive assessment of health indicators among tribal populations in Odisha, India (Odisha Tribal Family Health Survey): a community-based, cross-sectional studyResearch in... by Jaya Singh Kshatri, Kavitha AK, Tanveer Rehman, Haimanti Bhattacharya, Dinesh Bhuyan, Asit Mansingh, Uttam Kumar Sahoo, Moushumi Nayak, Swagatika Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

“…Gaps persisted in antenatal care (40.3% completed four or more visits) and hygienic menstrual practices (35.8% of women). …”
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Association of anthropometric indices with rs9939609 FTO gene polymorphism among overweight/obese women with breast cancer: a case-control study by Huma Naqeeb, Bismillah Sehar, Sami Siraj, Ali Madi Almajwal, Bibi Hajira, MoezAlIslam Faris, Sharifa AlBlooshi, Ali Saad R. Alsubaie, Mahpara Safdar, Iftikhar Alam, Falak Zeb

“…This study aimed to assess the interactions between single nucleotide polymorphism (SNP) rs9939609 of the FTO gene, anthropometric indices, and BC risk among pre- and post-menopause women with overweight/obesity in Pakistan.MethodsThis retrospective case–control study conducted on a convenience sample of 200 women divided into two groups: a case group comprised of 100 women diagnosed with BC, and control group comprised of 100 (age and menopausal status matched healthy women). …”
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Sustained Impact of an Intramural Faculty Leadership Training Program at an Academic Medical Center by Nahata L, Gerhardt CA, Way DP, Nikahd M, Mehta LS, Etzkorn LK, Satiani B, Guertin M, Martin DR

“…School of Medicine, Kalamazoo, MI, USA; 7Department of Surgery at The Ohio State University College of Medicine, Columbus, OH, USA; 8Department of Anesthesiology at The Ohio State University College of Medicine, Columbus, OH, USACorrespondence: Daniel R Martin, Department of Emergency Medicine at The Ohio State University College of Medicine, 760 Prior Hall, 376 West 10th Avenue, Columbus, OH, 43210, USA, Tel +1 614 531 1322, Fax +1 614 293 3124, Email Daniel.Martin@osumc.eduPurpose: To examine the sustained impact of a faculty leadership program at an academic health center (AHC) on participants’ perceived effectiveness in leadership skills and leadership attainment compared to faculty controls.Methods: The sample included 95 faculty members who participated in the year-long Faculty Leadership Institute (FLI). …”
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Metabolomics in drugs research on zebrafish-based cardiotoxicity models: endothelial and mitochondrial dysfunction, oxidative stress by N. E. Moskaleva, P. M. Rezvanov, V. M. Samoylov, V. G. Varzieva, S. N. Baskhanova, V. V. Tarasov, E. A. Smolyarchuk, D. A. Kudlay, S. A. Appolonova

“…Each of the analyzed compounds produced a specific metabolic “imprint” in Zebrafish samples, reflecting the mechanisms of their cardiotoxicity. …”
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Mental disorders and intimate partner violence perpetrated by men towards women: A Swedish population-based longitudinal study. by Rongqin Yu, Alejo J Nevado-Holgado, Yasmina Molero, Brian M D'Onofrio, Henrik Larsson, Louise M Howard, Seena Fazel

“…<h4>Methods and findings</h4>Using Swedish nationwide registries, we identified men from 9 diagnostic groups over 1998-2013, with sample sizes ranging from 9,529 with autism to 88,182 with depressive disorder. …”
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Estimated effect of media use on mothers’ vaccination of their children in Sub-Saharan Africa: a quasi-experimental propensity score matching analysis using DHS data by Melak Jejaw, Kaleb Assegid Demissie, Getachew Teshale, Demiss Mulatu Geberu, Misganaw Guadie Tiruneh, Asebe Hagos, Nigusu Worku, Endalkachew Dellie, Tesfahun Zemene Tafere

“…The final ATE estimate was 0.0828 among the samples. Quality of matching was good, and the estimates were insensitive to hidden bias. …”
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A Mindfulness-Based Lifestyle Intervention for Dementia Risk Reduction: Protocol for the My Healthy Brain Feasibility Randomized Controlled Trial by Ryan A Mace, Makenna E Law, Joshua E Cohen, Christine S Ritchie, Olivia I Okereke, Bettina B Hoeppner, Judson A Brewer, Stephen J Bartels, Ana-Maria Vranceanu

“…ConclusionsThe RCT will inform the development of a larger efficacy RCT (NIH stage 2) of MHB versus the HEP in a more diverse sample of older adults, testing mechanisms of improvements through theoretically driven mediators and moderators. …”
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