Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas by Yu Zhao, Chengcheng Zhou, Ling Zuo, Haoming Yan, Yuhan Gu, Hong Liu, Guiping Yu, Xiaorong Zhou

“…Serum samples were collected to quantify the expression levels of SFTA3 in LUAD patients. …”
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Needs and Wishes Towards Sex- and Gender-Sensitive Chronic Pain Management: A Qualitative Study with German General Practitioners by Piotrowski A, Schmidt A, Seuken N, Goldberg L, Kufeld N, Kersting C, Bencheva V, Thürmann P, Mortsiefer A

“…To inform the intervention design, we explored general practitioners’ (GPs) experiences and needs in managing this patient group, with a particular focus on the role of sex and gender.Methods: We conducted semi-structured telephone interviews with five GPs in Germany using a convenience sample. …”
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Identifying Current Practices and Areas for Improvement in Medication Management During Care Transition Through an Interprofessional Collaboration Framework by Solh Dost L, Maillard G, Cardoso E, Schneider MP

“…Patient partnership: recognised but requiring more consistency; 3. Role clarification: unclearly defined, causing inefficiencies; 4. …”
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Associations between measures of oestrogen exposure and severity of Fuchs endothelial corneal dystrophy by Eric D Wieben, Redion B Petrela, Chandra Divyash Chhetri, Ahmad Najafi, Zhaoqi Zhang, Tommy A Rinkoski, Michael P Fautsch, Saptarshi Chakraborty, Amy E Millen, Sangita P Patel

“…However, in women, the odds of severe FECD were increased with more months of lifetime oestrogen exposure (all women; log OR (95% credible interval): 1.3 (0.14 to 4.3)), higher concentrations of free estradiol (all women; 2.1 (0.0049 to 10)), greater % free estradiol (only women without TCF4 repeat expansion; 1.3 (0.16 to 3.8)) and higher concentrations of SHBG (only women with TCF4 repeat expansion; 2.2 (0.45 to 9.1)).Conclusions While the application of these data is constrained by the limited number of participants, a clinic-based sample, small number of men compared with women and single-point measures of serum hormone measures, these data suggest that FECD severity is associated with higher oestrogen exposures in women but not men and may be dependent on TCF4 repeat expansion status.…”
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Dyslipidemia in the Russian Federation: population data, associations with risk factors by O. M. Drapkina, A. E. Imaeva, V. A. Kutsenko, A. V. Kapustina, Yu. A. Balanova, S. A. Maksimov, G. A. Muromtseva, M. B. Kotova, N. S. Karamnova, S. E. Evstifeeva, O. A. Litinskaya, M. S. Pokrovskaya, N. A. Imaeva, E. M. Filichkina, O. E. Ivlev, G. E. Svinin, L. I. Gomanova, Yu. V. Doludin, I. A. Efimova, A. L. Borisova, B. M. Nazarov, E. B. Yarovaya, T. V. Repkina, T. O. Gonoshilova, A. V. Kudryavtsev, N. I. Belova, L. L. Shagrov, M. A. Samotrueva, A. L. Yasenyavskaya, E. N. Chernysheva, S. V. Glukhovskaya, I. A. Levina, E. A. Shirshova, E. B. Dorzhieva, E. Z. Urbanova, N. Yu. Borovkova, V. K. Kurashin, A. S. Tokareva, Yu. I. Ragino, G. I. Simonova, V. S. Shramko, V. N. Nikulin, O. R. Aslyamov, G. V. Khokhlova, A. V. Solovyova, A. A. Rodionov, O. V. Kryachkova, Yu. Yu. Shamurova, I. V. Tantsyreva, I. N. Baryshnikova, M. G. Ataev, M. O. Radjabov, M. M. Isakhanova, M. A. Umetov, L. V. Elgarova, I. A. Khakuasheva, E. I. Yamashkina, M. V. Esina, T. A. Kunyaeva, A. M. Nikitina, N. V. Savvina, Yu. E. Spiridonova, E. A. Naumova, A. A. Keskinov, V. S. Yudin, S. M. Yudin, A. V. Kontsevaya, S. A. Shalnova

“…These disorders occurred more often in women, and they were better informed about their cholesterol levels and more often received lipid-lowering therapy. …”
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Safety, Adequacy, and Accuracy of Transvaginal Ultrasound-Guided Tru-Cut Biopsy of Gynaecologic Tumours: A Retrospective Single-Centre Study by Munachiso Iheme Ndukwe, Dominik Karasek, Denisa Pohanková, Ivan Praznovec, Petra Bretova, Martin Stepan, Dominik Habes, Jan Laco, Akaninyene Eseme Ubom, Milan Vosmik, Igor Sirak

“…Most of the inadequate samples were obtained from overweight and obese women (5/7, 71.4%), with only one biopsy sample taken in the majority of the inadequate biopsies (5/7, 71.4%). …”
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Microbiological profile and antibiotic susceptibility of body fluids or swabs of acute leukemia patients with sepsis in a tertiary care hospital by Arka Karmakar, Atreyi Chakraborty, Krishnendu Bandyopadhyay, Biswajit Biswas, Sankar Kumar Das, Atanu Roy, Sayan Chatterjee, Mayank K Vidyarthi, Chayanik Ghosh, Pradip K Bej, Jeker Ali, Akashleena Datta

“…Aims and Objectives: To identify the bacteria and fungi causing sepsis in children with acute leukemia and study their antimicrobial profile. Materials and Methods: This descriptive observational study with a cross-sectional study design involved 100 consecutive children admitted to the inpatient department with acute leukemia and clinical sepsis with an acute rise of pediatric sequential organ failure assessment score of more than 2. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Our findings emphasise the importance of LUTS being managed in primary care where possible, as in addition to cost savings and reduced waiting times, this is a more accessible option for patients, who tend to be more comfortable and confident being treated by familiar clinicians or in more familiar environments. …”
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Molecular investigation on measles cases rise and variants co-circulation in the Lazio region, Italy by Cesare Ernesto Maria Gruber, Silvia Gioacchini, Lavinia Fabeni, Martina Rueca, Licia Bordi, Eleonora Lalle, Melissa Baggieri, Paola Bucci, Raoul Fioravanti, Roberto Giuseppetti, Eliana Specchiarello, Pietro Giorgio Spezia, Giulia Berno, Fabrizio Carletti, Gabriella De Carli, Maria Concetta Fusco, Alessandra Barca, Paola Scognamiglio, Antonella Marchi, Emilio D’Ugo, Enrico Girardi, Francesco Vairo, Fabio Magurano, Fabrizio Maggi

“…We analyzed the first cases of measles reported in Lazio (Central Italy) from September 2023 to March 2024, combining molecular characterization and phylogenetic analysis with epidemiological investigation to identify transmission chains and evaluate the sensitivity of PCR tests adopted on circulating viral strains. Methods We tested samples collected through routine measles and rubella surveillance for IgM, IgG and Real-Time PCR. …”
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Microbial landscape of wounds in patients with combat trauma of extremities by Bubman L.I., Topolyanskaya S.V., Rachina S.A., Gladkih M.A., Usova T.V., Karpov V.V., Molochnikov A.Yu., Nechaev A.I., Khan S.O., Emomadov A.M., Zakharov N.S., Kharchenko E.I., Lytkina K.A., Marchenko I.P., Buriev I.M., Melkonyan G.G.

“…The wound samples were cultured on nutrient media and microorganisms were identified in accordance with standard methods and procedures. …”
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Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination by R. V. Royuk, S. K. Yarovoy, N. A. Guseva, Sh. L. Voskanyan, V. V. Royuk, D. B. Rodin

“…The obtained data was analyzed using descriptive statistics methods.Results. Average age of patients was 65,4 +– 3,27; 78% of the patients were men. …”
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Streptococcus agalactiae colonization is common among pregnant women with HIV infection and is neither predicted by hospital tier nor trimester in Mwanza, Tanzania by Paul H. Ngayomela, Richard Kiritta, Boniface A. Remi, Sophyrose T. Mboya, Nyambura Moremi, Dismas Matovelo, Fridolin Mujuni, Stephen E. Mshana, Claudia Daubenberger, Ruth N. Zadoks, Jeremiah Seni

“…Results The overall proportion of S. agalactiae colonization was 24.5% (214/872) [95% CI: 21.7 − 27.5%], and was significantly higher in the HIV infected group [63.1% (70/111)] than in the HIV-negative group [18.9% (144/761)]; OR (95% CI) = 7.33 (4.77–11.29, p-value < 0.001)]. Colonization was more prevalent in the rectal samples compared to vaginal samples [21.1% versus 8.83%, respectively; p-value < 0.001)] and S. agalactiae recovery was higher using CHROMagarTMStrepB agar compared to blood agar [24.4% versus 18.8%, respectively, p-value = 0.004]. …”
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Experimental pleural empyema model in rabbits: Why, how and what are the next steps by Cvijanović Vlado, Vojvodić Danilo, Đurđević Dragan, Jović Milena, Stanić Vojkan, Sekulović Leposava, Perić Tijana

“…The use of new therapeutic methods to prevent development of fibrothorax as the final complication of the human pleural infections requires research with experimental animals. …”
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Clarithromycin-resistant Helicobacter pylori in Africa: a systematic review and meta-analysis by Komla Mawunyo Dossouvi, Tchilabalo Bouyo, Simon Sognonnou, Ephraim Ehidiamen Ibadin, Lu-chao Lv, Bissoume Sambe Ba, Abdoulaye Seck, Sika Dossim, Fábio Parra Sellera, Makhtar Camara, Amr El Kelish, Stella Ifeanyi Smith

“…Conclusion To enhance the accuracy and validity of surveillance data for H. pylori in Africa, there is an urgent need for implementing standardized microbiological methods for resistance detection. The prevalence of CRHp reported in this study was very similar to the overall global prevalence and there is a need for more representative studies on CRHp in Africa. …”
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The Use of Image and Performance Enhancing Drugs During the Covid-19 Lockdown: a Cross-Cultural Study on Potential Users and Associated Risks by I. De Luca, F. Di Carlo, J. Burkauskas, A.R. Dores, M.A. Gómez-Martínez, A. Szabo, H. Fujiwara, C. Monteiro, M. Di Nicola, M. Mazza, G. Sani, D. Luciani, M. Pettorruso, M. di Giannantonio, I. Cataldo, G. Esposito, G. Martinotti, O. Corazza

“…Online shoppers of IPEDs were mainly men who reported higher scores on the Exercise Addiction Inventory. One or more IPEDs classifiable as “potentially at-risk” were used by 66.3% of the sample. …”
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Respiratory pathogens in children with acute lower respiratory infection detected through multiplex real-time PCR by María del Pilar Montilla-Velásquez, Diego Mauricio Galvis-Trujillo, Suli Liliana Lizcano-Gamboa, Gisell Adriana Cobos, Angela Tatiana Rojas-Pinto, Daniel Mauricio Rincón-Fernández, Paola Jimena Soler-Rincón, María Alejandra Perdomo-Rivas, Diana Carolina Orozco-Vanegas, María Consuelo Mor-Rodríguez

“…Materials and methods: Cross-sectional study conducted in 81 children hospitalized between September 2019 and March 2020 at the Clínica Cafam and in whom nasopharyngeal swab samples were collected for microbiological identification using the Allplex™ multiplex RT-PCR assay. …”
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Histomorphological scoring of murine colitis models: A practical guide for the evaluation of colitis and colitis-associated cancer by Marianne Remke, Tanja Groll, Thomas Metzler, Elisabeth Urbauer, Janine Kövilein, Theresa Schnalzger, Jürgen Ruland, Dirk Haller, Katja Steiger

“…Therefore, we aimed to develop an easy-to-use and reproducible score for standardized assessment of colitis and associated cancer models. Methods: In this study, samples from three different colitis models with and without associated cancer formation were analyzed to develop a universal, robust, and reproducible score for the grading of murine colitis models using the following three parameters: 1. …”
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Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility by Jing Yang, Lingtao Yang, Ying Zhou, Fengyang Cao, Hongkun Fang, Huan Ma, Jun Ren, Chunyu Huang, Lianghui Diao, Qiyuan Li, Qionghua Chen

“…Methods We conducted a comprehensive computational analysis integrating publicly available endometrial transcriptomic datasets with prospectively collected samples. …”
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Chronobiological Changes in Biochemical Hemorrheological Parameters and Cytokine Levels in the Blood of Diabetic Patients on Hemodialysis: A Cross-Sectional Study by Fernando A. Lima, Juliana S. Monção, Mariana S. Honorio, Mahmi Fujimori, Danielle C. H. França, Aron C. M. Cotrim, Emanuelle C. H. França, Aline C. França-Botelho, Danny Laura G. Fagundes-Triches, Patrícia G. F. Marchi, Adenilda C. Honorio-França, Eduardo L. França

“…A deeper understanding of these factors could lead to more personalized and effective treatment strategies, ultimately improving patient outcomes and enhancing their quality of life.…”
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Detection of Trypanosoma lewisi from rodents residing in the densely populated residential regions along the coastal areas of Banyuwangi Sub District, Indonesia by April Hari Wardhana, Frenky Laksana Putra, Aditya Yudhana, Dyah Haryuningtyas Sawitri, Ening Wiedosari, Mujiyanto Mujiyanto, Swastiko Priyambodo, Mufasirin Mufasirin, Penny Humaidah Hamid, Yudhi Ratna Nugraheni, Aan Awaludin, Priyono Priyono, Alan Payot Dargantes, Makoto Matsubayashi

“…Conclusion: Statistical analysis revealed that T. lewisi was more prevalent in R. tanezumi compared to R. norvegicus. …”
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