100% oxygen mobilizes stem cells and up-regulates MIF and APRIL in humans: a new point on the hormetic dose curve by Kent J. MacLaughlin, Gregory P. Barton, Julia E. MacLaughlin, Jacob J. Lamers, Matthew D. Marcou, Matthew J. O’Brien, Rudolf K. Braun, Marlowe W. Eldridge

“…A positive outcome presents the potential to create and refine oxygen treatment protocols, expand access, and optimize patient outcomes.MethodsHealthy 30–35-year-old volunteers were exposed to 100% normobaric oxygen for 60 min, M-F, for 10 exposures over 2 weeks. …”
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Clinical Characteristics of 76 Patients with IgG4-Related Hypophysitis: A Systematic Literature Review by Yujuan Li, Hua Gao, Zhen Li, Xinxin Zhang, Yizhi Ding, Fengao Li

“…Further clinical studies with larger sample sizes are warranted.…”
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Echocardiographic Assessment of Cardiac Structure and Function of Centenarians: A Systematic Review by Andrea Sonaglioni, Gian Luigi Nicolosi, Giovanna Elsa Ute Muti-Schünemann, Alessio Polymeropoulos, Michele Lombardo, Paola Muti

“…These studies analyzed limited sample sizes of centenarians using different methodologies. …”
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Adaptive measurement of cognitive function based on multidimensional item response theory by Robert D. Gibbons, Diane S. Lauderdale, Robert S. Wilson, David A. Bennett, Tesnim Arar, David A. Gallo

“…We present results for a prototype CAT (pCAT‐COG) for assessment of global cognitive function. METHODS We sampled items across five cognitive domains central to neuropsychological testing (episodic memory [EM], semantic memory/language [SM], working memory [WM], executive function/flexible thinking, and processing speed [PS]). …”
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The Effect of Transfusion and Hypoxia on Cells in an in vitro Model of the Neurovascular Unit by A. A. Ivkin, E. V. Grigoriev, E. D. Khilazheva, A. V. Morgun

“…Intensive SIR demonstrated short-term but more deleterious than hypoxia, effect on cells in the NVU model. …”
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Sleep, Health Care–Seeking Behaviors, and Perceptions Associated With the Use of Sleep Wearables in Canada: Results From a Nationally Representative Survey by Karianne Dion, Meggan Porteous, Tetyana Kendzerska, Ashley Nixon, Elliott Lee, Massimiliano de Zambotti, Sheila N Garland, Mandeep Singh, Gino De Luca, Samuel Gillman, Andrée-Ann Baril, Dave Gallson, Rebecca Robillard

“…ObjectiveThis study aims to (1) determine the prevalence and sociodemographic predictors of using sleep wearables in Canada, (2) evaluate the perceived effects of wearable use on sleep and stress, (3) compare sleep and health care–seeking behaviors in users and nonusers, and (4) investigate the moderating effects of wearable use on the association between sleep and anxiety. MethodsAn online survey investigating sleep and mental health was distributed to a representative sample of 1200 Canadians. …”
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Occupational health complaints and demographic features of farmers exposed to agrochemicals during agricultural activity by Dhananjayan Venugopal, Ravichandran Beerappa, Deepika Chauhan, Panjakumar Karunamoorthy, Mala Ambikapathy, Thamaraikannan Mohankumar, Avinash Gaikwad, Shridhar Kondhalkar

“…Health complaints were significantly more common in the exposed group: 35% reported fatigue (compared to 20% in controls, χ² = 5.51, p = < 0.05). …”
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Navigating HOPE (Hypermobile Online Pain managemEnt): Perspectives and Experiences From People With Hypermobile Ehlers–Danlos Syndrome or Hypermobility Spectrum Disorder on a Condi... by Min Tze Chew, Emre Ilhan, Sarah Dennis, Leslie L. Nicholson, Sarah Kobayashi, Cliffton Chan

“…The programme topics included were based on a modified Delphi of a large sample of stakeholders: people with hEDS/HSD and healthcare practitioners who are experienced with managing these conditions. …”
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Impact of the COVID-19 pandemic on the diagnosis, tumor characteristics, and survival outcomes of colorectal cancer: a retrospective cohort study by Enver Yarikkaya, Merve Cin, Sena Ecin-Demezoglu, Beste Noyan-Mod, Mert Mahsuni Sevinc, Yakup Bozkaya, Nevra Dursun-Kepkep

“…DESIGN: Retrospective cohort study SETTING: Tertiary-care center PATIENTS AND METHODS: We included 284 patients newly diagnosed with CRC, stratified into two cohorts: those diagnosed one year before and during the first year of the pandemic. …”
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WORK EXPERIENCE INTERNSHIP THROUGH THE EYES OF TECHNICAL UNIVERSITY STUDENTS (ON THE MATERIALS OF SOCIOLOGICAL RESEARCH) by Alexandr Yu. Myagkov, Maria V. Grigorieva, Irina V. Zhuravleva, Svetlana L. Zhuravleva

“…The aim of the investigation is to study the problem of efficiency of work experience internship in a technical university and its role in the education of future professionals (problem has been investigated in the framework of the research project «Monitoring of social well-being and problems of professional adaptation of ISPEU students»).Methods. While carrying out of sociological research, selection of respondents was occurred on the multistage combined (serially-nested) model of sample among students I, III and V courses of six faculties of full-time course of ISPEU. …”
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Práticas e nível de conhecimento sobre doença cerebrovascular em um hospital universitário: Parte 2. educação médica na nova era de tratamento do infarto cerebral Knowledge and att... by Charles André, Letícia L. Vermelho, Ronir Raggio, Mônica F. Costa, Sérgio A. P. Novis

“…The importance of a thorough cardiac evaluation following stroke and of the intimate relation between cardiac and cerebral ischemic disease is also unclear to this group. More hours of stroke teaching and practical training in stroke could possibly fill these gaps.…”
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Elevated MS4A2 and IgE interaction in nasal polyps contributing to poor postoperative prognosis in patients with eosinophilic chronic rhinosinusitis by Mika Nakano, Naoko Okada, Natsuki Inoue, Akihiro Hatano, Sota Yamaguchi, Hiroko Inoue, Mamoru Yoshikawa

“…This study investigated the involvement of MS4A2, a component of the IgE receptor, in the pathogenesis of refractory eCRS. Methods: NP tissue samples were collected from 47 patients with eCRS who underwent sinus surgery and classified into refractory and nonrefractory groups based on postoperative outcomes. …”
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Nontraumatic headaches in the emergency department: identifying clinical associations and predictive warning signs of intracranial pathologies by Abdulaziz M. Alghamdi, Abdulkarim M. Alghamdi, Yousof Fahad Allarakia, Arwa S. Alghamdi, Abdulaziz S. Alrashid, Abdulwhab M. Alotaibi, Reem Addas, Ahmed I. Lary

“…DESIGN: Retrospective chart review SETTINGS: Medical center in Jeddah PATIENTS AND METHODS: Data were collected from all patients who presented to the ED with nontraumatic headaches and underwent brain computed tomography (CT) scans from September 2021 to September 2022. …”
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Comparative In Vitro Analysis of Composite Resins Used in Clear Aligner Attachments by Francesca Gazzani, Denise Bellisario, Chiara Pavoni, Loredana Santo, Paola Cozza, Roberta Lione

“…This study aimed to evaluate and compare the mechanical properties, thermal behavior, and wear performance of the hybrid composite Aligner Connect (AC) and the flowable resin (Connect Flow, CF). <b>Methods:</b> Twenty samples (ten AC and ten CF) were reproduced. …”
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Immune Subtypes in Sepsis: A Retrospective Cohort Study Utilizing Clustering Methodology by Zhao J, Dai R, Zhao Y, Tan J, Hao D, Ren J, Wang X, Chen Y, Peng H, Zhuang Y, Zhou S, Chen Y

“…Identifying distinct clinical phenotypes may enable more targeted therapeutic interventions and improve patient care.Objective: This study aims to use clustering analysis techniques to identify different immune subtypes in sepsis patients and explore their clinical relevance and prognosis.Methods: The study included 236 patients from the EICU at Shanghai Tenth People’s Hospital, who met the Sepsis 3.0 diagnostic criteria. …”
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The impact of the COVID-19 pandemic shelter in place on glycemic control, blood pressure control, and body mass index among diabetic patients at Kaiser Permanente Northern Californ... by Kyle Yamamoto, Maqdooda Merchant, Akshay Bommireddi, Joseph Vu, Seema K. Pursnani

“…We sought to quantify the impact of California’s 2020 SiP order on various health parameters in the Kaiser Permanente Northern California (KPNC) diabetic population. Methods This retrospective cohort study included 168,621 diabetic patients, stratified by pre-pandemic HbA1c level. …”
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Beta-glucans from biomass of plant and microbial origin by N. Yu. Sharova, B. S. Manzhieva, A. A. Printseva, T. V. Vybornova

“…Determined the content of β-glucans, amino-nitrogen, glucose, disaccharides in grinding grain rye, rye biomass, the biomass of A. niger, the supernatants by colorimetric methods. Determination of chitin in biomass and qualitative determination of chitosan in supernatants of hydrolysates was carried out using chitosan sulfate sample and subsequent microscopy.The results of the research showed that (1→3)(1→4)-β-D-glucans in grain grinding are 10.2 ± 0.2 % in terms of dry matter, which exceeds the content of polysaccharide in the grain of standard quality by 1.5 – 3 times. …”
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Metabolomic Profiling of Erector Spinae Plane Block for Breast Cancer Surgery by Ekin Guran, Ozan Kaplan, Serpil Savlı, Cigdem Sonmez, Lutfi Dogan, Suheyla Unver

“…Accordingly, VEGF and cortisol peaks were more moderate in group ESP. In conclusion, we think that ESP block, which provides adequate analgesia, is an acceptable approach in terms of modulating immune responses in breast cancer surgery.…”
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Association of atherogenic index of plasma with kidney dysfunction in diabetic individuals: findings from two national population-based studies by Lingling Zhu, Tiansu Lv, Siyuan Song, Ying Tan, Yun She, Xiqiao Zhou, Jiangyi Yu, Qianhua Yan

“…This study aims to clarify the association of AIP with kidney dysfunction in diabetic individuals. Methods This cross-sectional study analyzed a representative sample of participants aged 20 years and older from the United States (n = 2,386, NHANES 2007–2018) and Korea (n = 698, KNHANES 2012). …”
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Myeloid-derived suppressor cells in multiple myeloma patients at the immune recovery and after high-dose chemotherapy and hematopoietic stem cell transplantation by T. V. Tyrinova, E. V. Batorov, T. A. Aristova, G. Yu. Ushakova, S. A. Sizikova, V. V. Denisova, A. A. Ostanin, E. R. Chernykh

“…The association of early MM relapse after auto-HSCT with the lower count of G-MDSCs and the lower count of arginase-1+ M-MDSCs at the engraftment suggests that MDSCs is involved in the restriction of homeostatic proliferation as a factor for more effective immune recovery.…”
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