Reproducible Effects of Sex and Acquisition Order on Multiple Global Signal Metrics: Implications for Functional Connectivity Studies of Phenotypic Individual Differences Using fMR... by Henry W. Chase, Danella M. Hafeman, Merage Ghane, Alexander Skeba, Tyler Brady, Haris A. Aslam, Richelle Stiffler, Lisa Bonar, Simona Graur, Genna Bebko, Michele Bertocci, Satish Iyengar, Mary L. Phillips

“…Findings Adopting a training/testing sample structure to the analysis, we found no evidence of reproducible brain/behavior relationships despite identifying regions and connections that reflect reliable between‐scan individual differences. …”
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Metagenome association study of the gut microbiome revealed biomarkers linked to chemotherapy outcomes in locally advanced and advanced lung cancer by Zhe Zhao, Kailun Fei, Hua Bai, Zhijie Wang, Jianchun Duan, Jie Wang

“…However, the relationship between the intestinal flora and chemotherapy outcomes remains unclear and was investigated in this study. Methods We analyzed baseline stool samples from patients with locally advanced and advanced lung cancer before chemotherapy treatment, through metagenomics of the gut microbiota. …”
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Systems biology-based assessment of immune responses to whole cell and acellular pertussis vaccines by Mariana Leguia, Antón Vila-Sanjurjo, Diana Juarez, Alejandra Garcia-Glaessner, Ana I. Gil, Mayita Alvarez, Rubelio Cornejo, Sami Cherikh, Casey E. Gelber, Johannes B. Goll, Leigh M. Howard, Natalia Jimenez-Truque, Kathryn M. Edwards, C. Buddy Creech, Claudio F. Lanata

“…We also used standard serologic methods to assess immunogenicity, and correlated these results with transcriptional and translational signatures. …”
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A survey of pediatric dentists' caries-related treatment decisions and restorative modalities – A web-based survey by Hassan S. Halawany, Fouad Salama, Vimal Jacob, Nimmi Biju Abraham, Tarfa Nasser Bin Moharib, Abdulfatah Samih Alazmah, Jawaher Abdulaziz Al Harbi

“…Conclusion: The prevalence of use of composite resin to restore primary teeth was higher compared to glass ionomer cements and amalgam whereas a limited use of esthetic pediatric crowns was found among the sample surveyed. Esthetic pediatric crowns were more utilized by male compared to female participants. …”
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Intimate partner violence against women living with HIV in Lesotho: evidence from the 2023/24 DHS data set by Gebresilassie Tadesse, Girum Nakie, Gidey Rtbey, Techilo Tinsae, Setegn Fentahun, Mulualem Kelebie, Tigist Kifle Tsegaw, Getachew Muluye Gedef, Getasew Kibralew, Fantahun Andualem

“…A weighted sample of 467 women aged 15–49 years who were living with HIV was included. …”
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Chromosomal instability by low-coverage whole-genome sequencing assay predicts prognosis in bladder cancer patients underwent radical cystectomy by Qi Ding, Hailiang Zhu, Bo Fan, Lisheng Wang, Xiaohua Jin, Cheng Cao, Ying Shi, Zhijiang Fan, Wenjian Tu, Feng Li

“…Abstract Purpose To investigate chromosomal instability (CIN) in tumor tissue from radical bladder resection and to evaluate whether it can be used as a biomarker for the molecular typing of (BC). Methods DNA was extracted from formalin-fixed paraffin-embedded samples of 50 BC patients who were followed up to March 23 2023 using the Qiagen nucleic acid kits. …”
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The dosimetric value and safety evaluation of 3D printed bolus in adjuvant intensity-modulated radiotherapy after radical mastectomy for breast cancer: a prospective cohort study by Yaxue Wang, Hanzong Li, Wendie Hu, Bohan Li, Yujie Du, Fengyan Li

“…Conclusions The use of 3DPB in breast cancer radiotherapy is effective, achieving higher and more uniform dose distribution and better target conformity compared to without 3DPB. …”
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A surveillance study to determine the accuracy of mild traumatic brain injury diagnosis in an emergency department: protocol for a retrospective cohort study by Ian D Cameron, Ilaria Pozzato, Ashley Craig, Bamini Gopinath, Mark Gillett, Annette Kifley, Kim Van Vu, Susanne Meares, Anthony Liang

“…This project will advance existing research findings by estimating the occurrence of mTBI among those attending an ED and quantifying the accuracy of mTBI diagnoses recorded by ED staff through a comprehensive audit of ED records.Methods and analysis Retrospective chart reviews (between June 2015 and June 2016) of electronic clinical records from an ED in Sydney (New South Wales, Australia) will be conducted. …”
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The associations between gut microbiota and fecal metabolites with intelligence quotient in preschoolers by Jinghua Long, Jiehua Chen, Huishen Huang, Jun Liang, Lixiang Pang, Kaiqi Yang, Huanni Wei, Qian Liao, Junwang Gu, Xiaoyun Zeng, Dongping Huang, Xiaoqiang Qiu

“…However, due to limitations such as the small sample size, unclear causality, and the complexity of metabolites, more validation studies are still needed to further elucidate the mechanisms and stability of these associations.…”
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Procedure‐specific simulation for vaginal surgery training: A randomized controlled trial by Roxana Geoffrion, Nicole A. Koenig, Geoffrey W. Cundiff, Catherine Flood, Momoe T. Hyakutake, Jane Schulz, Erin A. Brennand, Terry Lee, Joel Singer, Nicole J. Todd

“…Baseline characteristics were similar, except for more fourth‐year control residents. After adjustment of confounders (age, level, baseline knowledge), GRS scores showed significant differences overall (mean difference 8.2; 95% confidence interval [CI]: 0.2–16.1; p = 0.044) and for VH (mean difference 12.0; 95% CI: 1.8–22.3; p = 0.02). …”
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Association between FIB-4 index and lower extremity arterial disease in MASLD patients: a cross-sectional study by Chunxia Zhang, Yuchen Ying, Yuanhui Ru, Ziliang Wu, Yumeng Tian, Pingping Shen, Shiyuan Cao, Jing Zhang, Ri Liu

“…This suggests that further studies with larger sample sizes are needed to explore these relationships more comprehensively.…”
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Enhancing cognitive function through blood flow restriction: An effective resistance exercise modality for middle-aged women by Dohyeon Lee, Kyeongho Byun, Sewon Lee

“…Purpose: Cognitive decline progresses more rapidly in women than in men, with a higher prevalence of neurodegenerative diseases observed in females. …”
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The Group‐basEd Telehealth behavioral WEight Loss Program Among Breast Cancer Survivors: A Pilot and Feasibility Study by Kelly C. Allison, Courtney McCuen‐Wurst, Allie Raevsky, Nathaniel Holmes, Macy Goldbach, Carmen E. Guerra, Katharine A. Rendle, Tamara J. Cadet, Robert S. Krouse, Julia Tchou

“…Future studies should test this intervention in larger, more diverse samples. Trail Registration ClinicalTrials.gov identifier: NCT04855552, posted April 22, 2021…”
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Enhanced Recovery after Intensive Care (ERIC): study protocol for a German stepped wedge cluster randomised controlled trial to evaluate the effectiveness of a critical care telehe... by Ulrich Mansmann, Claudia Spies, Ursula Marschall, Reinhard Busse, Christine Adrion, Bjoern Weiss, Nicolas Paul, Elke Berger, Jörg Caumanns, Simone Rosseau

“…Besides, there is an increasing number of elderly patients with chronic diseases being treated in the intensive care unit (ICU). More than half of the survivors of critical illness suffer from medium-term or long-term cognitive, psychological and/or physical impairments after ICU discharge, which is recognised as post-intensive care syndrome (PICS). …”
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Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence by Ji‐Hua Shi, Wen‐Zhi Guo, Yang Jin, Hua-Peng Zhang, Chun Pang, Jie Li, Pål‐Dag Line, Shui‐Jun Zhang

“…HER2 in HCC biology needs further explorations. Methods Clinical and mRNA data of HCC patients were obtained from TCGA HCC cohort, GSE89377 and GSE115018. …”
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Morphometric analysis of the fifth lumbar vertebra (L5): Anatomical dimensions and clinical implications in South Indian population by Nandini Bhat, Lakshmisha Rao, Ashwija Shetty, Souhardya Das, Nom Bhukya Kumar Naik, Vanishri Nayak, Sushma Prabhath, Kurian Alapatt, Suhani Sumalatha

“…Further research with larger and more diverse samples is recommended to validate and expand these findings.…”
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Impact of obesity on clinical outcomes in patients with high-risk pulmonary embolism: A comparative analysis by Ziv Shachar, Marlon V. Gatuz, Adam Folman, Maguli S. Barel, Rami Abu-Fanne, Dmitry Abramov, Mamas A. Mamas, Ariel Roguin, Ofer Kobo

“…This study aimed to investigate the impact of obesity on clinical outcomes in patients with high-risk PE. Methods: We conducted a retrospective analysis of US adult patients hospitalized with high-risk PE from 2016 to 2019 using the National Inpatient Sample database. …”
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Randomised placebo-controlled multicentre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community-acquired pneumonia: a trial protocol for the... by Patrick M Meyer Sauteur, Julia Anna Bielicki, Malte Kohns Vasconcelos, Regina Santoro, Michael Coslovsky, Marco Lurà, Kristina Keitel, Tanja Wachinger, Svetlana Beglinger, Ulrich Heininger, Johannes van den Anker

“…Introduction Community-acquired pneumonia (CAP) causes around 10 hospitalisations per 1000 child-years, each associated with an average 13 non-routine days experienced and more than 4 parent workdays lost. In adults, steroid treatment shortens time to clinical stabilisation without an increase in complications in patients with CAP. …”
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The value of post radiotherapy prostate specific antigen dynamics for prostate cancer risk stratification models by Jane Shortall, Eliana Vasquez Osorio, Andrew Green, Kimberley Reeves, David Wong, Tanuj Puri, Peter Hoskin, Ananya Choudhury, Marcel van Herk, Alan McWilliam

“…Conclusion: PSA dynamics within the first three-years of post-radiotherapy follow-up for prostate cancer were more prognostic of BCR than pre-treatment risk-groups, suggesting PSA dynamics could be used to re-stratify BCR risk during early follow-up.…”
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Evidence Graph Analysis of Postoperative Pain Sensitization Induced by Perioperative Sleep Deprivation by XUE Jianjun, WANG Caihong, GUO Lingling, LI Xiuxia, ZHANG Jie, XU Ziqing, HOU Huaijing, YANG Kehu

“…Only 2 studies suggested that sleep disorders were not significantly associated with postoperative pain sensitization, and ten studies were uncertain whether sleep deprivation could induce postoperative pain sensitization.ConclusionsOverall evidence shows that sleep deprivation can induce postoperative pain sensitization, but the evaluation dimensions are limited and the methodological quality of the included literature needs to be improved. More high-quality, large-sample and standardized clinical studies should be carried out in the future to provide better scientific basis for clinical work.…”
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