Measurement of schizophrenia symptoms through speech analysis from PANSS interview recordings by Michelle Worthington, Michelle Worthington, Georgios Efstathiadis, Vijay Yadav, Vijay Yadav, Isaac Galatzer-Levy, Isaac Galatzer-Levy, Isaac Galatzer-Levy, Alan Kott, Emanuel Pintilii, Tejendra Patel, Colin Sauder, Inder Kaul, Stephen Brannan, Anzar Abbas

“…By contrast, negative symptoms were associated with decreased amount of speech, slower speech, and longer, more varied pauses.DiscussionA large sample of PANSS recordings was successfully processed using open source methods for phenotyping and strong relationships between speech characteristics and symptoms from these recordings were observed. …”
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Response of dissolved organic matter and bacterial community to anthropogenic disturbances in a plateau lake by Yue Meng, Yue Meng, Xin Jiang, Xin Jiang, Yue Li, Chun Qing, Chun Qing, Xingyu Long, Pinhua Xia, Pinhua Xia

“…Similarly, α and β diversity indices for bacterial communities showed no marked variation (P > 0.05) between highly and lightly disturbed areas in both water and sediment samples. Nevertheless, co-occurrence network analysis revealed more negatively correlated links and longer average path length with stronger disturbances. …”
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Archives and Health program for dementia: A pilot study of a non-pharmacological creative arts-based intervention protocol by Sara Uboldi, Lorenza Iannacci, Vanda Menon, Alessandro Bortolotti, Giulia Candeloro, Alessandro Crociata, Valeria Pica, Angelo Romagnoli, Maria Tartari, Andrea Fabbo, Alessandra Marasco, Pier Luigi Sacco

“…Future studies with larger samples are necessary to confirm these findings and explore their clinical implications more robustly.…”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Extensive experiments demonstrate that SMT achieves up to <inline-formula> <tex-math notation="LaTeX">$2.71\times $ </tex-math></inline-formula> faster training and <inline-formula> <tex-math notation="LaTeX">$775\times $ </tex-math></inline-formula> faster inference compared to traditional patch-cropping methods, while maintaining comparable accuracy and requiring less storage compared to existing SOTA methods. …”
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Second-harmonic generation microscopy of murine scleral remodeling by collagenase and reparative collagen mimetic peptides by Daniel E. Savage, Daniel E. Savage, Aldo Tecse, Aldo Tecse, Jiaxi Zhou, James A. Germann, Mark R. Buckley, Mark R. Buckley, Robert O. Baratta, Brian J. Del Buono, Eric Schlumpf, Michael Telias, Michael Telias, Susana Marcos, Susana Marcos

“…This investigation is a pilot study to determine if a novel collagen mimetic peptide (CMP) has a reparative function for scleral collagen organization after collagenase digestion, a cause for scleral thinning and increased creep rates, as this may have application in the pharmacologic treatment of myopia.MethodsFresh, ex vivo, scleral tissue samples from 3 albino Sprague–Dawley rats (5 eyes) and from 8 C57/Black mice (8 eyes) underwent sequential collagenase digestion and treatment with a CMP solution. …”
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A Re-Examination of a Previous Study Relating to Topical Body Formulations: Validating Gene Expression Transcription at Multiple Time Points, and Protein Expression and Translation... by Alan D. Widgerow, Mary E. Ziegler, Faiza Shafiq

“…From a translational perspective, histological analysis showed that TransFORM enhanced elastin fiber presence in the dermal–epidermal junction (DEJ) more effectively than FTB at both days 3 and 7. FTB-treated samples maintained a gap in the DEJ, while TransFORM-treated samples exhibited increased cellular proliferation and DEJ undulation, indicative of a healthier regenerative response. …”
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The Field Assessment of Quiescent Egg Populations of <i>Aedes aegypti</i> and <i>Aedes albopictus</i> during the Dry Season in Tapachula, Chiapas, Mexico, and Its Potential Impact... by José Ignacio Navarro-Kraul, Luis Alberto Cisneros Vázquez, Keila Elizabeth Paiz-Moscoso, Rogelio Danis-Lozano, Jesús A Dávila-Barboza, Beatriz Lopez-Monroy, Rosa María Sánchez-Casas, Marco Antonio Domínguez-Galera, Pedro Christian Mis-Avila, Ildefonso Fernandez-Salas

“…Evolutionary characteristics for the two species including partial egg hatching, ambient-regulated quiescence, the ability of the embryo to survive for a more extended period intra-seasonally, the egg sticking to inner container walls, demands urgent operational research to achieve successful egg-proof larval container methods.…”
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Colostrum-Derived Melatonin Plus PEG Microspheres Modulate the Oxidative Metabolism of Human Colostrum Phagocytes by Caroline G. Silva, Viviane F. Luz, Victor L. Nunes, Ana B. M. Verzoto, Aron C. de M. Cotrim, Wagner B. dos Santos, Eduardo L. França, Adenilda C. Honorio-França

“…Therefore, the objective of this study was to extract melatonin from human colostrum, develop and characterize PEG microspheres with the extracted melatonin adsorbed onto them, and evaluate the effects of this system on the oxidative metabolism of colostrum phagocytes. Methods: Thirty colostrum samples were collected; ten were used for melatonin extraction, while twenty were used to obtain phagocytes. …”
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Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia by Yanxin Chen, Peifang Jiang, Jingjing Wen, Zhengjun Wu, Jiazheng Li, Yuwen Chen, Lingyan Wang, Donghui Gan, Yingyu Chen, Ting Yang, Minhui Lin, Jianda Hu

“…However, resistance to GC is observed more frequently than resistance to other chemotherapy agents in patients with ALL relapse. …”
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Atlantic mackerel population structure does not support genetically distinct spawning components [version 2; peer review: 1 approved, 2 approved with reservations] by Imanol Aguirre-Sarabia, Alice Manuzzi, Dorte Bekkevold, Natalia Díaz-Arce, Jessica Gomez-Garrido, Teunis Jansen, Marta Gut, Tyler S. Alioto, Sonia Sanchez-Maroño, Martin Castonguay, Naiara Rodriguez-Ezpeleta, Paula Álvarez

“…Such reference genome was used to map Restriction-site-associated sequencing (RAD-seq) reads for SNP discovery and genotyping in more than 500 samples distributed along the species range. …”
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Role of Iron in Children With Immunoglobulin A Nephropathy and Macrohematuria-Induced Acute Kidney Injury by Shingo Ishimori, Tomoko Horinouchi, Tomohiko Yamamura, Junya Fujimura, Naohiro Kamiyoshi, Hiroshi Kaito, Yuriko Tanaka, Hiroyoshi Matsukura, Wataru Shimabukuro, Yuko Shima, Azusa Kawaguchi, Yoshinori Araki, Koichi Nakanishi, Shigeo Hara, Kandai Nozu

“…Thirty percent of adults with MH-AKI, and especially those who are older, show progression to chronic kidney disease. Methods: We evaluated the immunohistopathologic characteristics of renal biopsy samples from pediatric patients with MH-AKI IgAN and controls, using Berlin Blue to identify iron, CD163 (a hemoglobin-scavenging receptor), and CD68 (a total macrophage marker), then compared the findings against the clinical characteristics of the patients. …”
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BRAF Mutations in an Italian Regional Population: Implications for the Therapy of Thyroid Cancer by Eleonora Monti, Michela Bovero, Lorenzo Mortara, Giorgia Pera, Simonetta Zupo, Elena Gugiatti, Mariella Dono, Barbara Massa, Gian Luca Ansaldo, Giusti Massimo

“…The study’s aim was to evaluate the BRAF mutations’ incidence in an Italian regional population. Subjects and Methods. 70 Caucasian patients born in Liguria with indeterminate or suspicious cytological diagnoses. …”
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Fast and Flexible Inference Framework for Continuum Reverberation Mapping Using Simulation-based Inference with Deep Learning by Jennifer I-Hsiu Li, Sean D. Johnson, Camille Avestruz, Sreevani Jarugula, Yue Shen, Elise Kesler, Zhuoqi (Will) Liu, Nishant Mishra

“…Using simulated light curves, we find SBI can produce more accurate SMBH parameter estimation with 10 ^3 –10 ^5 times speed up in inference efficiency compared to traditional methods. …”
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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023) by Abbas Raeisabadi, Mohsen Nosratabadi, Zahra Abtahian, Sadegh Khodavaisy, Neda Kiasat, Ali Rezaei-Matehkolaei, Rasoul Mohammadi, Javad Javidnia, Leila Faeli, Iman Haghani, Hossein Zarrinfar, Raheleh Alhashemi, Mojtaba Taghizadeh Armaki, Seyed Reza Aghili, Maryam Moazeni, Mahdi Abastabar, Hamid Badali

“…Abstract Purpose The incidence of Mucormycosis has increased during the last decades globally due to more patients being at risk for these life-threatening infections. …”
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Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer by Georgia Porter, Murray D. Norris, Minoti Apte, Angelica M. Merlot

“…For the first time, we characterized the expression and spatial locations of ER stress markers, BiP and CHOP, in tumor-associated cells and assessed their prognostic significance in a panel of pancreatic ductal adenocarcinoma (PDAC) patient samples. Methods: Multiplex immunofluorescence was performed on tumor microarrays and images were analyzed using HALO AI software. …”
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Detection of zika virus disease caused by the Asian lineage of the zika virus at Kenya's Lamu island by Gathii Kimita, John Collins, Beth Mutai, Esther Omuseni, Clement Masakhwe, Stephen Ocholla, Allan Lemtudo, George Awinda, Rachel Githii, Gerald Kellar, John Waitumbi

“…Objectives: We report the first confirmed cases of Zika virus (ZIKV) disease (ZVD) in Kenya and provide the associated genomic sequences. Methods: The study is part of a prospective febrile illness surveillance study in Kenya. …”
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Microvascular Anastomosis in Practice: A Pilot Study on Microsurgical Training Efficiency by Florin-Vlad Hodea, Andreea Grosu-Bularda, Andrei Cretu, Catalina-Stefania Dumitru, Vladut-Alin Ratoiu, Eliza-Maria Bordeanu-Diaconescu, Raducu-Andrei Costache, Razvan-Nicolae Teodoreanu, Ioan Lascar, Cristian-Sorin Hariga

“…The structured training model promoted more consistent progress and superior microsurgical technique. …”
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Effect of fire on the diversity and trophic levels of soil fauna in Hyrcanian forests after 5 years (case study: Galandroud forest) by Zeinab Ahmadi, Davoud Kartoolinejad, Mariam Molashahi, Masoumeh Shayanmehr

“…The abundance of almost all species was more in the control forests rather than the fire-burned ones, except for coleopteran beetles and the ants. …”
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Factors associated with client satisfaction and implementation challenges for community-based health insurance in Ethiopia: beneficiaries' perspectives by Habtamu Negesse, Tarekegn Negese, Shewayirga Assalf, Abdu Oumer, Kedir Nuredin, Tewkel Reshid, Kedir Teji Roba, Kedir Teji Roba

“…This study was to assess factors associated with client satisfaction and implementation challenges for CBHI in Ethiopia.MethodsA mixed-methods (quantitative and qualitative) survey was employed using face-to-face interviews combined with key informant interviews (KII) using appreciative inquiry to learn more about the practice of CBHI. …”
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Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes by Matilde Sbriscia, Dalila Colombaretti, Angelica Giuliani, Silvia Di Valerio, Lucia Scisciola, Iryna Rusanova, Anna Rita Bonfigli, Fabiola Olivieri, Jacopo Sabbatinelli

“…Routine biomarkers were measured on serum samples using commercially available methods. One-way ANOVA/ANCOVA, logistic regression, and Spearman’s correlations were used to compare the TyG index among groups and to assess its correlations with biochemical variables. …”
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