Immunogenic cell death-related genes as prognostic biomarkers and therapeutic insights in uterine corpus endometrial carcinoma: an integrative bioinformatics analysis by Tianfei Yi, Zhenglun Yang, Peng Shen, Yan Huang

“…While ICD systems have been widely adopted in oncological research, their specific utilization for Uterine Corpus Endometrial Carcinoma (UCEC) investigations has received comparatively little attention.MethodsThe ICD score was assessed using single-sample gene set enrichment analysis (ssGSEA). …”
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Decoding multiple myeloma: single-cell insights into tumor heterogeneity, immune dynamics, and disease progression by Zhenzhen Zhao, Zhijie Zhao, Zhiheng Lin, Lu Fan, Zhikai Xiahou, Yujiang Dong, Weiying Bao

“…Despite therapeutic progress, disease heterogeneity and resistance highlight the need for new strategies targeting the tumor microenvironment and neuroimmune axis.MethodsThis investigation exploited single-cell RNA sequencing (scRNA-seq) to analyze MM and high-risk smoldering multiple myeloma (SMMh) samples, identifying 11 distinct cell types. …”
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Exploring the impact of pregnancy on cognitive function: a comparative study in a low-income setting by Syed Aman Ali, Muhammad Sualeh, Ghana Raza, Mohammad Sabeeh ul haq, Laiba Hissan, Duaa Zafar, Muhammad Adnan, Syed Kauser Ali

“…Therefore, this study aimed to establish a clear link between cognitive function and pregnancy. Methods A cross-sectional comparative study was conducted at a tertiary care hospital in Karachi, Pakistan with a sample size of 160 participants, divided into two groups of 83 pregnant (aged 25.63 ± 4.22) and 77 nonpregnant women (aged 27.79 ± 3.89). …”
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Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities by Armando S. Martinez, David Momtaz, Travis Kotzur, Alexandra McLennan, Abdullah Ghali, Farhan Ahmad, Ebubechi Adindu, Alan C. Santiago-Rodriquez, Ali Seifi, Brian Smith

“…Our study aims to identify and describe those demographic factors associated with poor outcomes after spinal fusion with instrumentation in neuromuscular scoliosis to reduce health disparities and improve postoperative outcomes. Methods: A retrospective analysis was conducted using Healthcare Cost and Utilization Project data from 2016 to 2020, encompassing a random sample of 20% of procedures in the United States. …”
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COVID‐19 and coworker conflict among emergency medical service clinicians by Gennaro Di Tosto, Halia Melnyk, Jonathan R. Powell, Eben Kenah, Christopher B. Gage, Ashish R. Panchal, Ann Scheck McAlearney

“…Our objective was to evaluate whether changes in the EMS environment during the COVID‐19 pandemic were associated with increased workplace conflict. Methods This evaluation was a cross‐sectional analysis of a random sample of 19,497 national certified EMS clinicians who were selected to receive an electronic survey in April 2022. …”
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Distribution of government health financing benefits among women who delivered in public institutions in Bangladesh: a nationally representative cross-sectional studyResearch in co... by Md. Abdur Rafi, Urby Saraf Anika, Dewan Tasnia Azad, Shafiun Nahin Shimul, Mohammad Jahid Hasan, Md. Golam Hossain

“…The objective of this study was to investigate the distribution of public health financing benefits among women who delivered in public facilities in Bangladesh. Methods: This study was conducted based on the data from the Bangladesh Demographic and Health Survey (BDHS) 2022, which includes a sample of 3360 women (age 15–49 years) who had a history of institutional delivery during two years preceding the survey. …”
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Adherence to iron-folic acid supplementation and its associated factors among pregnant women in Kenya: A multilevel data analysis of the 2022 Kenyan Demographic and Health Survey. by Gebrie Getu Alemu, Dagnew Getnet Adugna, Amare Mesfin, Muluken Chanie Agimas, Lemlem Daniel Baffa, Habtamu Wagnew Abuhay, Mekuriaw Nibret Aweke, Tewodros Getaneh Alemu, Nebebe Demis Baykemagn

“…Weighted samples of 8,460 participants were used in the analysis. …”
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Arterial stiffness measured by pulse wave velocity correlated with cognitive decline in hypertensive individuals: a systematic review by Botagoz Aimagambetova, Taylor Ariko, Stacy Merritt, Tatjana Rundek

“…Studies demonstrated that individuals with elevated blood pressure (BP) and PWV are more likely to experience worse cognitive decline compared to those with either condition alone. …”
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Effect of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in stable chronic obstructive pulmonary disease: A systematic review and meta-analysis. by Xuqin Du, Yan Li, Jiansen Wang, Youqin Jiang, Yaji Liu, Dingrong Zhang, Qi Wu, Shouhong Long

“…More rigorously designed, high-quality, multicenter trials are needed to confirm these results.…”
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Applications and Challenges of Advanced Molecular Diagnostics in Clinical Microbiology and Epidemiology: A Literature Review by Ujwala Damineni, Amulya Varshini Banka, Sri Ram Charan Gundapaneni, Neha Narayan, Yethindra Vityala

“…In epidemiology and surveillance, molecular approaches have advanced more rapidly than in clinical use and are recognised for their superior discrimination. …”
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Views of democracy and society and support for political violence in the USA: findings from a nationally representative survey by Garen J. Wintemute, Sonia L. Robinson, Andrew Crawford, Daniel Tancredi, Julia P. Schleimer, Elizabeth A. Tomsich, Paul M. Reeping, Aaron B. Shev, Veronica A. Pear

“…Results The analytic sample included 8620 respondents; 50.5% (95% confidence interval (CI) 49.3%, 51.7%) were female; and weighted mean (± standard deviation) age was 48.4 (± 18.0) years. …”
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PROBLEMS IN THE DIAGNOSIS AND TREATMENT OF ANCA-ASSOCIATED SYSTEMIC VASCULITIS: IN THE FOCUS OF ANCA-NEGATIVE PAUCI-IMMUNE GLOMERULONEPHRITIS by T. V. Beketova, N. F. Frolova, E. S. Stolyarevich, M. Yu. Volkov, O. N. Kotenko, E. N. Aleksandrova

“…One of the most common  causes of rapidly progressive glomerulonephritis (GN)  is the so-called pauci-immune crescentic GN that is characterized  by no luminescence  in kidney tissue samples during immunofluorescence microscopy and by the hyperproduction of antineutrophil cytoplasmic antibodies (ANCA). …”
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Identification of Carbapenemase within Class 1 Integron Structure in Intrinsically Colistin-resistant Enterobacteriaceae by Negin Bolourchi1, Omid Azizi2, Mahdi Rohani1, Soha Seyyedi Abhari1, Armaghan Soltani Shirazi1, Farzad Badmasti1, 3

“…Here, we characterized carbapenemase resistance genes and their carriage within class 1 integron structures in clinical intrinsically colistin-resistant Enterobacteriaceae. Methods: Clinical samples were collected from six general hospitals in Tehran and Torbat-e-Heydarieh, Iran, from 2018 to 2020. …”
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Protective factors for suicidal ideation and suicide attempts in adolescence: a longitudinal population-based cohort study examining sex differences by Victoria Bakken, Stian Lydersen, Norbert Skokauskas, Anne Mari Sund, Jannike Kaasbøll

“…This study investigated the associations between protective factors in early adolescence and the subsequent outcomes of SI and SA a year later, while also examining sex differences in these associations. Methods This study utilized data from a representative sample at two timepoints, T1 (N = 2464, 50.8% females, mean age = 13.7, SD = 0.6) in 1998 and T2 (N = 2432, 50.4% females, mean age = 14.9, SD = 0.6) one year later, collected as part of the longitudinal Youth and Mental Health Study (YAMHS) in Norway. …”
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Impact of fear of coronavirus disease 2019 on attention-deficit/hyperactivity disorder traits associated with depressive symptoms, functional impairment, and low self-esteem in uni... by Tomoko Suzuki, Toshiyuki Ohtani, Michiko Nakazato, Ariuntuul Garidkhuu, Basilua Andre Muzembo, Shunya Ikeda

“…The current study aimed to examine whether the association between ADHD traits and outcomes was partially mediated by fear of COVID-19 using mediation analysis. Methods: A cross-sectional study was conducted in a sample of university students in medical-related faculties (n = 1,166). …”
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Digital, Personalized Clinical Trials Among Older Adults, Lessons Learned From the COVID-19 Pandemic, and Directions for the Future: Aggregated Feasibility Data From Three Trials A... by Lindsay Arader, Danielle Miller, Alexandra Perrin, Frank Vicari, Ciaran P Friel, Elizabeth A Vrany, Ashley M Goodwin, Mark Butler

“…Differences between these cohorts were analyzed using chi-square tests for categorical outcomes and 2-tailed independent-sample t tests for continuous outcomes. …”
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Neuropsychological development of children with biliary atresia after liver transplantation by A. V. Syrkina, I. E. Pashkova, A. R. Monakhov, O. V. Silina, E. V. Chekletsova, S. Yu. Oleshkevich, I. B. Komarova, O. M. Tsirulnikova

“…Studies on developmental outcomes in children are mostly limited to small samples; there are no such studies in the Russian Federation.Objective: to determine the cognitive outcomes in children undergoing one-stage or two-stage surgical treatment of biliary atresia.Materials and Methods. 83 children were divided into groups: 36 children underwent transplantation without previous surgical interventions (group 1), 47 children underwent the Kasai palliative portoenterostomy (group 2). …”
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Feasibility of a Mental Health App Intervention for Emergency Service Workers and Volunteers: Single-Arm Pilot Study by Denise Meuldijk, Mark Deady, Daniel A J Collins, Douglas O Williams, Richard A Bryant, Samuel B Harvey

“…While the pilot study showed encouraging trends toward improved MH, further research with a larger sample size is needed to determine its efficacy. Participants furthermore suggested improvements in app navigation and content clarity, emphasizing the need for a more intuitive user experience. …”
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Integrative Analysis of Whole-Genome and Transcriptomic Data Reveals Novel Variants in Differentially Expressed Long Noncoding RNAs Associated with Asthenozoospermia by Maria-Anna Kyrgiafini, Maria Katsigianni, Themistoklis Giannoulis, Theologia Sarafidou, Alexia Chatziparasidou, Zissis Mamuris

“…This study aimed to identify and prioritize variants in differentially expressed (DE) lncRNAs found exclusively in asthenozoospermic men, focusing on their impact on lncRNA structure and lncRNA–miRNA–mRNA interactions. <b>Methods</b>: Whole-genome sequencing (WGS) was performed on samples from asthenozoospermic and normozoospermic men. …”
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Histomorphometric evaluation of bone regeneration using autogenous bone and beta-tricalcium phosphate in diabetic rabbits by Živadinović Milka, Andrić Miroslav, Milošević Verica, Manojlović-Stojanoski Milica, Prokić Branislav, Prokić Bogomir, Dimić Aleksandar, Ćalasan Dejan, Brković Božidar

“…Histology revealed active new bone formation peripherally with centrally located connective tissue, newly formed woven bone and well incorporated residual grafts in all treated defects. Control samples showed no bone bridging of defects. There was a significantly more new bone in autogeonous graft (53%) compared with β-tricalcium phosphate (30%), (p < 0.030) and control (7%), (p < 0.000) groups. …”
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