ARHGAP25: a novel player in the Pathomechanism of allergic contact hypersensitivity by Domonkos Czárán, Péter Sasvári, Kende Lőrincz, Krisztina Ella, Virág Gellén, Roland Csépányi-Kömi

“…Here, we investigate its role in the pathogenesis of the more complex inflammatory process of contact hypersensitivity.MethodsFor sensitization, the abdomens of wild-type and ARHGAP25 deficient (KO) mice on a C57BL/6 background, as well as bone marrow chimeric mice, were coated with 3% TNCB (2-chloro-1,3,5-trinitrobenzene) or acetone in the control group. …”
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Factors influencing reselection of village doctors in rural-oriented tuition-waived medical education program in Shanghai, China: a cross-sectional study by Jing Gao, Juhua Zhang, Chenlei Shi, Aiqin Fan, Peng Zhang

“…This study aims to identify the factors that influence the reselection intention and perceptions of NGVDs of RTME program in Shanghai.MethodsIn 2023, a questionnaire survey was conducted among a sample of NGVDs enrolled in the RTME program in 8 districts of Shanghai. …”
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Children and adolescents with overweight or obesity exhibit poor cardiorespiratory performance and elevated energy expenditure during an exercise task. by Carlos Sepúlveda, Matías Monsalves-Álvarez, Rodrigo Troncoso, Gerardo Weisstaub

“…This study aims to investigate CRF performance and energy expenditure in response to an exercise task among children and adolescents.<h4>Methods</h4>The sample consisted of 242 children and adolescents aged 8-16 years, categorized by healthy weight, overweight, obesity, and levels of cardiorespiratory fitness (low or high). …”
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Development and Validation of Prognostic Characteristics Associated With Chromatin Remodeling‐Related Genes in Ovarian Cancer by Guansheng Chen, Wenjing Li, Jiayi Guo, Lingyu Liu, Yongjun Wang

“…Chromatin remodeling accomplishes specific chromatin condensation at distinct genomic loci and plays an essential role in epigenetic regulation associated with various processes related to cancer development. Methods Differentially expressed genes (DEGs) between OC and control samples were screened from The Cancer Genome Atlas (TCGA) and Genotype‐Tissue Expression (GTEx) databases, combined with chromatin remodeling‐related genes (CRRGs) obtained from the GeneCards database to identify differentially expressed CRRGs (DECRRGs). …”
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Are Cannabis-Based Medicines a Useful Treatment for Neuropathic Pain? A Systematic Review by Nawaf Almuntashiri, Basma M. El Sharazly, Wayne G. Carter

“…Hence, future RCTs will need to have larger numbers and be more extended studies that explore optimal dosing and delivery methods and identify patient subgroups that are most likely to benefit. …”
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Differences in IL-1β and IL-6 levels in the gingival crevicular fluid during acute phase of orthodontic tooth movement between juveniles and young adults by Vujačić Amila, Konić Aleksandra, Pavlović Jasna, Todorović Vera, Vukićević Vladanka, Jevremović Danimir, Milošević-Jovčić Nadežda

“…GCF was sampled from both the control and treatment sites right before the beginning (the baseline) and 24 h, 72 h and 168 h upon initiation of OTM. …”
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Improving medication adherence and viral load suppression in pediatric, adolescent, and young adult patients living with HIV using a specialty pharmacy by Timothy J. Howze, Tiffany M. Nason, Susan D. Carr, Steve M. Pate, Anderson L. Roe, Nehali D. Patel

“…Objective This study evaluates the effects of implementing a specialty pharmacy model on adherence and virological suppression in pediatric and AYA individuals living with HIV. Methods Specialty pharmacy operations began at St. …”
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Remote ischaemic conditioning for neurological disorders—a systematic review and narrative synthesis by Ali Alhashimi, Marharyta Kamarova, Sheharyar S. Baig, Krishnan Padmakumari Sivaraman Nair, Tao Wang, Jessica Redgrave, Arshad Majid, Ali N. Ali

“…However, to establish the efficacy of RIC across different neurological disorders, further trials with larger sample sizes and more diverse patient populations are warranted. …”
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Prevalence of cardiovascular risk factors and cardiovascular prevention quality in primary healthcare in Russia and European countries: EURIKA Study results by S. A. Boytsov

“…In the RF, 604 patients were enrolled in the study at 26 clinical centres. Material and methods. The participating patients were recruited during routine clinical visits. …”
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Exploring the Dynamics of Dietary Self-Monitoring Adherence Among Participants in a Digital Behavioral Weight Loss Program: Model Development Study by Hui Lin, Min Yang, Zhiheng Zhou, Yu Zhang, Ning Deng

“…Notably, the presence of tailored feedback and the higher levels of social support were associated with greater goal pursuit and more sustained behavioral practice. ConclusionsThis study highlights the potential of ACT-R modeling for dynamic analysis of self-monitoring behaviors in digital interventions. …”
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Effectiveness of family-centered intervention programs on objectively measured physical activity in children aged under 13: a meta-analysis of randomized controlled trials by Qian Wang, Lawrence T. Lam, Heng Lin, Wenxian Yang, Fuxian Yin, Yongwei Li

“…Future research should focus on larger, more diverse samples (e.g., populations in developing countries), utilize high-quality measurement tools, and novel outcomes (e.g., FMS) to better assess the effectiveness of these interventions.Trial registrationMeta-analysis PROSPERO: CRD42023488011.…”
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Parental neighbourhood perceptions and active commuting to school in children according to their sex using a self-organised map approach: a cross-sectional study by Javier Molina-García, Xavier García-Massó, Cristina Menescardi, Isaac Estevan, Ana Queralt

“…The sample comprised 808 children and one of their parents. …”
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Menopausal symptom burden as a predictor of mid- to late-life cognitive function and mild behavioral impairment symptoms: A CAN-PROTECT study. by Jasper F E Crockford, Dylan X Guan, Gillian Einstein, Clive Ballard, Byron Creese, Anne Corbett, Ellie Pickering, Adam Bloomfield, Pamela Roach, Eric E Smith, Zahinoor Ismail

“…We investigated these two relationships in a sample of postmenopausal females.<h4>Design</h4>Cross-sectional observational study.…”
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A compilation of 13 patients with metastatic colorectal cancer and concomitant BRAF and RAS family mutations by Jigisha Srivastav, Morgan E. Lehman, Joni K. Evans, Ravi Paluri, Caio Max Sao Pedro Rocha Lima

“…We reviewed over 750 samples from a database of CRC patients from Guardant360 and FoundationOne kept by the Wake Forest Baptist Health Comprehensive Cancer Center. …”
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(Non)specific interaction patterns in families raising a child with disability or chronic illness: a latent profile analysis by Ariadna Łada-Maśko, Urszula Sajewicz-Radtke, Paweł Jurek, Paweł Jurek, Michał Olech, Bartosz M. Radtke, Małgorzata Lipowska

“…The sample included 49 families of children with diabetes, 49 with intellectual disabilities, 28 with motor disabilities, and 53 healthy children. …”
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Latent profile analysis of moral courage and coping style among nursing interns: a multicenter cross-sectional survey by Xue Wang, Ruixin Zhang, Jie Chen, Jiao Wu, Zhi Huang

“…This study aimed to explore the current situation of moral courage and analyze its potential profiles and differences in coping styles among nursing interns. Methods In this cross-sectional descriptive study, a convenience sample of nursing interns (n = 1258) from 14 nursing schools in the three geographical areas of China was investigated. …”
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The impact of obesity on sleep, pulmonary and chest wall restriction in Osteogenesis Imperfecta: a pilot study by Ramona De Amicis, Vittorio Landoni, Simona Bertoli, Alessandro Sartorio, Andrea Aliverti, Antonella LoMauro

“…Reversing obesity in OI is even more challenging as knowledge of the diet and the physical activity suited for these patients is still scarce.…”
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Toward an intersectional equity approach in social–ecological transformations by Paula Andrea Sánchez-García, Krisztina Jónás, Kara E. Pellowe, Hanna Ekström, Mary Scheuermann, Lasse Loft

“…Abstract Non-technical summary Ensuring more equitable transformations requires addressing how different contextual dimensions of identity, such as gender and class, hinder equity. …”
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Budgetary Factors and the Quality of Education Service Delivery in Public Secondary Schools in Northern Division Kabale District. by Atwongyeire, Redeemer

“…The study used both a questionnaire and an interview guide as methods of data collection. Data was entered into the computer and analyzed by developing themes (headings) or subthemes that were derived from the study objectives. …”
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Mechanical Properties and Microscopic Mechanisms of Expansive Soil under the Action of Acid and Alkali Solutions by HU Bo, LI Wei, MA Kun, YUAN Rui-xiang, WANG Shuai, SUN Hui

“…[Objective] The aim of this study is to investigate the effects of acid-base conditions on the mechanical properties of expansive soil. [Methods] Expansive soil from Section C003 of the Yangtze-to-Huaihe Water Diversion Project was taken as the research object. …”
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