Development of the barriers to opioid access scale among individuals with chronic pain by Sujith Ramachandran, Stefan Kertesz, Emily Gravlee, Prachi Prajapati, John P. Bentley, Yi Yang

“…Objectives: The aim of this study was to develop an instrument to measure barriers to prescription opioid access among individuals with chronic pain and test its psychometric properties. Methods: This study used a cross-sectional online survey of a convenience sample of adults (>18 years) who reported any type of pain for at least 45 days or more in the previous 3 months. …”
Get full text

Genetic association between Class II division 1 and division 2 malocclusions with PAX9 (rs8004560) gene polymorphism in a tertiary care hospital by Monika SHUKLA, Munish REDDY, Kritanjali SINGH, Ruchi SAINI, Pradeep RAGHAV, Kaynat NASSER, Nupur SHARMA, Aastha KAMRANI, Shehla RAFIQUE, Tanjula SHAIR

“…The results showed that individuals with the AG genotype seemed to be more susceptible to the development of skeletal Class II div. 2 malocclusion. …”
Get full text

Analysis of CA1, CA3, and DG areas of the hippocampus, substance-P, and brain-derived neurotrophic factors expression in the presence of Ocimum sanctum Linn on the brain of the rat... by Made Bagus Auriva Mataram, Ulayatul Kustiati, Hevi Wihadmadyatami, Dwi Aris Agung Nugrahaningsih, Siti Isrina Oktavia Salasia, Dwi Liliek Kusindarta

“…Results: Results of the study revealed increased neuronal density in the CA1, CA3, and DG regions, and that these neurons were also more highly expressed in the neurotrophic factor BDNF and neuropeptide SP. …”
Get full text

In-house designed simulation courses versus society-accredited designs by international societies: A comparative analysis by Abramovich, Igor, Beilstein, Jakob, Kornemann, Eva, Berger-Estilita, Joana, Schröder, Torsten

“…Future research should include a broader sample, more rigorous content analysis, longitudinal follow-up, and detailed participant experience data to enhance the depth and applicability of findings.…”
Get full text

Chinese herbal medicine (Bu-Shen-Tian-Jing Formula) for outcomes of IVF in Chinese patients with polycystic ovary syndrome: A retrospective cohort study by Xiaoming Pan, Yinger Gu, Xian Zhang, Biwei Shi, Long Cui, Fangfang Wang, Fan Qu

“…Results: BSTJF helped patients with PCOS to get more retrieved oocytes (P<0.05) and fertilized oocytes (P<0.05). …”
Get full text

Association between visceral adiposity index and endometriosis: a population-based study by Jiajia Zhang, Qian Zhang, Tianyu Chu, Xian Chen, Hui Zhou, Dewu Xu, Chunlin Dong, Yibo Wu

“…The results of subgroup analyses showed that some specific demographic, lifestyle, and reproductive characteristics were not statistically significant in influencing the correlation between VAI and endometriosis (p &gt; 0.05 for all interactions).ConclusionOur study observed a statistically significant association between VAI and endometriosis. More prospective cohort investigations with large samples are required to further validate these findings because the etiology of endometriosis remains unclear.…”
Get full text

Identification of hub genes, diagnostic model, and immune infiltration in preeclampsia by integrated bioinformatics analysis and machine learning by Yihan Zheng, Zhuanji Fang, Xizhu Wu, Huale Zhang, Pengming Sun

“…Abstract Purpose This study aimed to identify novel biomarkers for preeclampsia (PE) diagnosis by integrating Weighted Gene Co-expression Network Analysis (WGCNA) with machine learning techniques. Patients and methods We obtained the PE dataset GSE25906 from the gene expression omnibus (GEO) database. …”
Get full text

Study of molecular genetic markers of Gilbert’s syndrome by A. A. Ivanova, A. A. Gurazheva, E. S. Mel’nikova, V. N. Maksimov, E. G. Nemcova

“…To study new molecular genetic markers of Gilbert’s syndrome (GS).Materials and methods. It was a case – control study. The GS group included 125 people (mean age 38.5 ± 11.9 years, 58.9% were men) with unconjugated hyperbilirubinemia; known causes of unconjugated hyperbilirubinemia were excluded. …”
Get full text

Association between ultra-processed foods and female infertility: a large cross-sectional study by Xiaoxiao Su, Ge Chen, Shaole Shi, Huijun Sun, Ying Su, Yunan He

“…Future prospective cohort studies with larger sample sizes are still needed to provide more stable evidence of the relationship between UPF intake and female infertility.…”
Get full text

Distribution and clinicopathological characteristics of G-CSF expression in tumor cells and stromal cells in upper tract urothelial carcinoma by Go Kobayashi, Yohei Sekino, Hikaru Nakahara, Kohei Kobatake, Keisuke Goto, Tetsutaro Hayashi, Kazuhiro Sentani, Nobuyuki Hinata

“…Abstract Background Urothelial carcinoma (UC) is a common type of malignant disease; however, the diagnostic and prognostic markers of upper urinary tract urothelial cancer (UTUC) remain poorly understood because of its rarity. Methods To clarify the clinicopathological significance of granulocyte-colony stimulating factor (G-CSF) in UTUC, we analyzed the expression and distribution of G-CSF in 112 upper tract urothelial carcinoma (UTUC) samples with immunohistochemistry. …”
Get full text

Unpacking the complexities in racial and ethnic discrimination and tobacco use and cannabis co-use behaviors among young adults in the U.S. by Stephanie Pike Moore, Craig S. Fryer, Eugenia Lee, Kymberle L. Sterling

“…This research sought to unravel some of the complex, multilayered experiences of RED and subsequent coping strategies to examine the impact on LCC use. Methods: Data come from a cross-sectional survey conducted among a nationally representative sample of U.S. young adults (n = 1,178) in May 2022. …”
Get full text

The MiBlend Randomized Trial: Investigating Genetic Polymorphisms in Personalized Responses to Fruit and Vegetable Interventions for Chronic Disease Prevention by Julia N. DeBenedictis, Na Xu, Theo M. de Kok, Simone G. van Breda

“…Therefore, this study aims to identify if genetic variants in relevant genes affect outcomes and responses to the dietary interventions. Methods: The literature review identified 15 polymorphic genes related to phytochemical metabolism, oxidative stress, and detoxification, which were tested in 146 participant samples using TaqMan and PCR analysis. …”
Get full text

The Relationship between Attention and Balance in Children with Cerebral Palsy: A Comparative Preliminary Study in Diplegia and Hemiplegia by mahrokh ghahari, Aliyeh Daryabor, mino kalantari, ashkan irani, zahra Shafiee

“…Given that children with diplegia exhibited weaker dynamic and static balance compared to those with hemiplegia, their balance deficits appear to demand more significant attentional resources. Due to the small sample size, further research is necessary to validate these findings.…”
Get full text

Enhanced Physiological Stress Response in Patients with Normal Tension Glaucoma during Hypoxia by Line Marie Dalgaard, Jeppe Vibæk, Rupali Vohra, Lars Thorbjørn Jensen, Barbara Cvenkel, Niels H. Secher, Niels Vidiendal Olsen, Miriam Kolko

“…To investigate whether patients with normal tension glaucoma (NTG) show an enhanced stress response to reduced oxygen supply compared to age-matched healthy controls, measured by serum adrenaline and endothelin-1 (ET-1) levels and changes in distal finger temperature. Methods. A thorough clinical characterization of patients with NTG and age-matched controls was performed prior to inclusion in the study. …”
Get full text

Prevalence of Gum Diseases Among Patients Attending the Diabetic Clinic at the Komfo Anokye Teaching Hospital: A Cross‐Sectional Study by Kwame Adu Okyere Boadu, Esther Priscilla Biamah Danquah, Elsa Kudiabor, Nana Atuahene Oti, John Billy Owusu Quarshie, Nana Bempong Owusu‐Ankomah

“…Only 26.7% attended dental check‐ups more than once yearly; 73.9% of rare attendees had periodontitis. …”
Get full text

Ehrlichia, Hepatozoon, and Babesia Coinfection Patterns Among Owned Dogs in Central Thailand by Rungrote Osathanon, Aeknarin Saechin, Chalisa Mongkolphan, Benjaporn Bhusri, Siriporn Tangsudjai

“…Animals Two thousand five hundred nineteen owned dogs presented with clinical abnormalities consistent with tick‐borne diseases between 2019 and 2023. Methods Retrospective study, blood samples were analyzed using multiplex PCR to assess infection rates. …”
Get full text

The development of the Compassion Satisfaction and Compassion Fatigue scale by Júlia Halamová, Martin Kanovský, Martin Kanovský, Katarina Krizova, Bronislava Šoková, Martina Baránková, Charles Figley

“…In addition, we wanted to create norms for the helping professional population. The research sample consisted of 2,320 participants from various helping professions.ResultsTo improve scalability, most of the scale items were removed. …”
Get full text

Outcomes of patients with COVID-19 pneumonia requiring lung resections in a third-level hospital by Diego Sánchez-Pereda, Emmanuel Peña Gomez-Portugal, Jorge Canto-Losa, Jorge Jaspersen-Álvarez, Javier E. Anaya-Ayala

“…This study aimed to give insight into common complications arising in patients with COVID-19 pneumonia that require lung resections. Methods This is a retrospective single-center study looking at conditions arising in patients with COVID-19 pneumonia who required lung resection for resolution between March 2020 and March 2021. …”
Get full text

Emotional analysis of operating room nurses in acute care hospitals in Japan: insights using ChatGPT by Kentaro Hara, Reika Tachibana, Ryosuke Kumashiro, Kodai Ichihara, Takahiro Uemura, Hiroshi Maeda, Michiko Yamaguchi, Takahiro Inoue

“…Future research with larger and more diverse samples is needed to validate these findings and explore the broader applications of AI in healthcare.…”
Get full text

Cold aortic flush after ventricular fibrillation cardiac arrest reduces inflammatory reaction but not neuronal loss in the pig cerebral cortex by Lisa Barones, Wolfgang Weihs, Alexandra Schratter, Andreas Janata, Petra Kodajova, Helga Bergmeister, Lukas Kenner, Michael Holzer, Wilhelm Behringer, Sandra Högler

“…Abstract This study aims to retrospectively compare two resuscitation methods (extracorporeal cardiopulmonary resuscitation (ECPR) vs. emergency preservation and resuscitation (EPR)) by pathohistologically assessing pig brains in a ventricular fibrillation cardiac arrest (VFCA) model. …”
Get full text