Elranatamab versus physician’s choice of treatment in patients with triple-class exposed/refractory multiple myeloma: an updated matching-adjusted indirect comparison by Isha Mol, Yannan Hu, Thomas W LeBlanc, Joseph C Cappelleri, Haitao Chu, Guido Nador, Didem Aydin, Isabel Perez Cruz, Patrick Hlavacek

“…A previous unanchored matchingadjusted indirect comparison (MAIC) of the MagnetisMM-3 (NCT04649359) and LocoMMotion (NCT040 35226) study reported significant improvements in progression-free survival (PFS) and overall survival (OS) with elranatamab versus physician’s choice of treatment. Materials & methods: We conducted an updated MAIC based on more recent data (28.4 months for MagnetisMM-3). …”

The frequency of cervical dentine hypersensitivity and possible etiological factors in an urban population: A cross-sectional study by Kolak Veljko, Ristić Tamara, Melih Irena, Pešić Dragana, Nikitović Ana, Lalović Marija

“…The prevalence of cervical DH in the investigated sample was relatively high. DH was more prevalent among females and significantly associated with frequent consumption of citrus fruits and energy drinks.…”
Get full text

Effect of Capacitive Radiofrequency on the Fibrosis of Patients with Cellulite by Rodrigo Marcel Valentim da Silva, Priscila Arend Barichello, Melyssa Lima Medeiros, Waléria Cristina Miranda de Mendonça, Jung Siung Camel Dantas, Oscar Ariel Ronzio, Patricia Meyer Froes, Hassan Galadari

“…The aim of this study was to evaluate the effects of low-temperature radiofrequency to confirm the thinning of the collagen tissue and interlobular septa and consequent improvement of cellulite. Methods. A sample of eight women was used to collect ultrasonographic data with a 12 MHz probe that measured collagen fiber thickness. …”
Get full text

Racial segregation and genomics-related knowledge, self-efficacy, perceived importance, and communication among medically underserved patients by Jemar R. Bather, Melody S. Goodman, Kimberly A. Kaphingst

“…We examined the potential impact of racial segregation on these genomics-related outcomes among medically underserved patients. Methods: We analyzed data from a sample of 546 patients recruited from a primary care clinic in St. …”
Get full text

Water Chemical Characteristics and Irrigation Suitability of Surface Water in Areas Around Yuelu Mountain in Xiangjiang River Basin by Zhong Qiao, Xiao Xiong, Zhang Cicheng, Zhang Xinping, Li Jiajie, Wang Dizhou, Yu Zhengliang, Liu Na

“…Water samples of precipitation, mountainous creek water, and Xiangjiang River water were collected from December 2020 to November 2021. …”
Get full text

Rare cell-based liquid biopsy for improved measurement of low-grade chronic inflammation by Stefan Schreier, Stefan Schreier, Stefan Schreier, Prapaphan Budchart, Suparerk Borwornpinyo, Suparerk Borwornpinyo, Panuwat Lertsithichai, Wannapong Triampo, Wannapong Triampo

“…The compensatory mechanisms involve the production or release of rare immature blood cell types that herein serve as important biomarker targets.MethodsA cell-based liquid biopsy platform, using negative selection, was used to detect circulating rare cells in comprehension, allowing simultaneous analysis of an immature cell panel from one sample. …”
Get full text

Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci by Xingling Tan, MD, Zhouyouyou Xiao, MB, Yao Wen, MD, Han Liu, MD, Wei Yu, MD

“…By revealing new associations and shared genetic pathways, our findings provide valuable insights into the pathophysiology of AR and pave the way for more effective targeted interventions to manage AR and its related diseases.…”
Get full text

Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients by David Heftrig, Ramona Sturm, Elsie Oppermann, Kerstin Kontradowitz, Katrin Jurida, Lukas Schimunek, Mathias Woschek, Ingo Marzi, Borna Relja

“…Furthermore, HLA-DR decreased after trauma and was even more profound by stimulation of monocytes. Ratio of monocytes to leukocytes was significantly increased at days 6 and 7 after trauma compared to HV. …”
Get full text

The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis. by David J Pascall, Elen Vink, Rachel Blacow, Naomi Bulteel, Alasdair Campbell, Robyn Campbell, Sarah Clifford, Chris Davis, Ana da Silva Filipe, Noha El Sakka, Ludmila Fjodorova, Ruth Forrest, Emily Goldstein, Rory Gunson, John Haughney, Matthew T G Holden, Patrick Honour, Joseph Hughes, Edward James, Tim Lewis, Samantha Lycett, Oscar MacLean, Martin McHugh, Guy Mollett, Yusuke Onishi, Ben Parcell, Surajit Ray, David L Robertson, Sharif Shabaan, James G Shepherd, Katherine Smollett, Kate Templeton, Elizabeth Wastnedge, Craig Wilkie, Thomas Williams, Emma C Thomson, COVID-19 Genomics UK (COG-UK) Consortium

“…We aimed to do this.<h4>Methods</h4>In this retrospective multi-centre clinical cohort sub-study of the COG-UK consortium, 1475 samples from Scottish hospitalised and community cases collected between 1st November 2020 and 30th January 2021 were sequenced. …”
Get full text

Delimitation of Landslide Areas in Optical Remote Sensing Images Across Regions via Deep Transfer Learning by Zan Wang, Shengwen Qi, Yu Han, Bowen Zheng, Yu Zou, Yue Yang

“…Automatic delimitation of landslide areas empowered by deep learning methods has drawn tremendous attention in recent years. …”
Get full text

Supporting Indigenous Family Caregivers of Children with Life-Threatening and Life-Limiting Illness in One Canadian Province: Healthcare Providers’ Perspectives by Jill M. G. Bally, Meridith Burles, Amaya Widyaratne, Victoria A. Spurr, Heather Hodgson-Viden, Roona Sinha

Get full text

Sono-urethrogram versus conventional urethrogram in the assessment of urethral stricture disease: A prospective comparative study by Akash Chitrakar, Baikuntha Adhikari, Udita Mishra, Arvind Kumar Shah, Robin Bahadur Basnet, Parash Mani Shrestha, Anil Shrestha

“…Further studies with larger sample sizes are warranted.…”
Get full text

Multiple high-risk human papillomavirus infections exacerbate cervical lesion risk: epidemiological evidence from suining, Sichuan by Yaling Jing, Jianhui Chen, Fang Lin, Xiaonan Huang, Yulin Liu, Mingcai Zhao, Chuan Ye, Lianfang Zhao, Xiaofang Liu, Jiayan Yang

“…Moreover, no data on HPV epidemiology in the Suining region of China have been published. Methods Cervical samples were collected from women undergoing gynecological examinations at the Suining Central Hospital. …”
Get full text

Agronomic and Quality Traits of 30 Eggplant Germplasm Resources from China by Jian Lyu, Li Jin, Xianglan Ma, Yansu Li, Mintao Sun, Ning Jin, Shuya Wang, Linli Hu, Jihua Yu

“…Of note, significant differences in the soluble protein, vitamin C, nitrate, soluble sugar, organic acid, and mineral contents was observed within the samples, with organic acids, vitamin C, and hardness contributing more to the total variation observed. …”
Get full text

The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin Aging by Feng Qin, Jiuzuo Huang, Wenchao Zhang, Mingzi Zhang, Zhenjiang Li, Loubin Si, Xiao Long, Xiaojun Wang

“…The goal of this study was to investigate paracrine mechanisms by which ASCs repair HDFs damage from UVB exposure. Methods. ASCs were cocultured with UVB-irradiated and nonirradiated HDFs. …”
Get full text

Development and validation of the climate change-related reproductive concerns scale (CCRCS) by Matteo Innocenti, Gabriele Santarelli, Chiara Comerci, Niccolò Carluccio, Enrico Anzaghi, Chiara Cadeddu

“…To address this imperative, our study develops the Climate Change-related Reproductive Concerns Scale (CCRCS) and evaluates its psychometric properties. Methods: CCRCS was developed and validated in a sample of 206 Italian adults aged 19 to 51. …”
Get full text

Exploring the Relationship Between Play During School Recess and Motor Performance in 6- to 8-Year-Old Children by Dagmar F. A. A. Derikx, Marina M. Schoemaker, Leila Faber, Suzanne Houwen, Esther Hartman

“…Objective: The aim of the current study was to examine whether children’s play activities and with whom 6- to 8-year-old children play during recess are related to their motor performance. Methods: The study sample consisted of 86 Dutch participants (mean age 6.92 ± 0.62 years, 58.1% boys). …”
Get full text

Clinical and radiological characteristics of parenchymal and meningeal spinal tuberculosis by Qiu-Lan Shan, Le Zhang, Xu-Wen Fu, Min Qi, Jia-Lu Wei, Wei Gan, Xiang Li, Ling-Jun Shen

“…Statistical analyses are performed using Chi-square tests, independent sample t-tests and non-parametric tests. Results Parenchymal spinal tuberculosis is more frequently associated with haematogenous pulmonary dissemination, exhibits a stronger inflammatory response and is linked to poorer nutritional status. …”
Get full text

Validation of a teaching model instrument for university education in Ecuador through an artificial intelligence algorithm by Jenniffer Sobeida Moreira-Choez, Tibisay Milene Lamus de Rodríguez, Aracelly Fernanda Núñez-Naranjo, Ángel Ramón Sabando-García, María Belén Reinoso-Ávalos, Cynthia Michel Olguín-Martínez, Daniel Omar Nieves-Lizárraga, Julieta Elizabeth Salazar-Echeagaray

“…Furthermore, the use of AI in the validation process enables a more precise interpretation of educational information, reinforcing the relevance of AI-supported models in optimizing teaching and learning processes.…”
Get full text

Comparative Evaluation of Microhardness and Degree of Polymerization of Dual-cure Resin Cement on Luting Composite Resin Endocrowns of 5.5mm and 7.5mm Thicknesses: An in-vitro Stud... by Prakruthi Nallikatte, Shony Mohan, Harsha Karunakaran, Ravichandran Rajagopal, Vivek Nair, Amal Shajahan

“…The ANOVA test results revealed a significant difference in the degree of polymerization between the groups (F = 144.873, p < 0.001).Conclusions: The study's statistical analysis was evident through  ANOVA and post hoc Tukey's tests. The sufficient sample size for each group enhanced the statistical power and allowed for a more accurate variability assessment.…”
Get full text