Multiparametric MRI for local staging in patients with suspected muscle-invasive bladder cancer: study protocol for a multicentre, non-inferiority randomised controlled trial (the... by Lambertus ALM Kiemeney, Janneke PC Grutters, Erik J.R.J. van der Hoeven, Janneke P.C. Grutters, Antoine G van der Heijden, Sebastiaan W van Koeverden, Lisa MC van Hoogstraten, Maarten de Rooij, Marloes van der Leest, Arnold Baars, Thierry N. Boellaard, Joost L. Boormans, Lars E.J. Bosboom, Quirijn J.A. van den Bouwhuijsen, Siebren Dijkstra, Cristina E. Firanescu, Jurgen J. Fütterer, Ernst P. van Haarst, Tom J.N. Hermans, Marina C. Hovius, Josephine C.B.M. Huige, Michael D.H. Kortleve, Anneke Kusters, Geert J.L.H. van Leenders, Saskia van der Meer, Richard P. Meijer, Harm H.E. van Melick, Laura S. Mertens, Gerd-Jan Molijn, Rinze Reinhard, Ivo G. Schoots, Petra C.G. Simons, Ruth Smit, Femke Struik, Julie Swillens, Charlotte J Tutein Nolthenius, Jeroen Veltman, Andre N. Vis, Thijn F. de Vocht, Jeanette van Vooren, Frank J. Wessels, Carl J. Wijburg, Dennis de Witte, Monique Arts-Thijssen, Guus Venderbosch

“…The aim of this randomised study is to determine whether multiparametric MRI (mpMRI) of the bladder, in combination with a single outpatient bladder tumour biopsy for histological confirmation, is a safer, faster, less costly and, therefore, more cost-effective diagnostic pathway than TURBT to detect or rule out MIBC.Methods and analysis BladParadigm is a two-arm multicentre randomised controlled trial (RCT) conducted in the Netherlands. …”
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Arterial Stiffness in Heart‐Healthy Indigenous Tsimane Forager‐Horticulturalists by Tianyu Cao, Edhitt C. Linares, Raul Quispe Gutierrez, Daniel Eid Rodriguez, Juana Bani Cuata, Michael I. Miyamoto, Christopher R. von Rueden, Daniel K. Cummings, Paul L. Hooper, Benjamin C. Trumble, Jonathan Stieglitz, Randall C. Thompson, Gregory S. Thomas, Hillard Kaplan, Daniel A. Duprez, David R. Jacobs, Michael Gurven

“…Carotid‐femoral pulse wave velocity was assessed using the foot‐to‐foot method in a smaller Tsimane sample (n=94) and compared with 3086 predominantly White US adults (mean age, 46.1±8.7 years; 54% women) from the FHS Gen3 (Framingham Heart Study Third Generation). …”
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Performance of GPT-4 for automated prostate biopsy decision-making based on mpMRI: a multi-center evidence study by Ming-Jun Shi, Zhi-Xiang Wang, Shuang-Kun Wang, Xuan-Hao Li, Yan-Lin Zhang, Ying Yan, Ran An, Li-Ning Dong, Lei Qiu, Tian Tian, Jia-Xin Liu, Hong-Chen Song, Ya-Fan Wang, Che Deng, Zi-Bing Cao, Hong-Yin Wang, Zheng Wang, Wei Wei, Jian Song, Jian Lu, Xuan Wei, Zhen-Chang Wang

“…Additionally, the Chain of Thought method enabled us to better understand the decision-making logic behind GPT-4. …”
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Community and hospital-based healthcare professionals perceptions of digital advance care planning for palliative and end-of-life care: a latent class analysis by Jacqueline Birtwistle, Gabriella Williamson, Samuel D Relton, Andy Bradshaw, Katherine E Sleeman, Maureen Twiddy, Pablo Millares-Martin, Suzanne Richards, Matthew J Allsop

“…Objective This study addresses this gap aiming to examine community and hospital-based healthcare professionals’ perceptions of Electronic Palliative Care Coordination Systems on advance care planning and the delivery of palliative care. Design and methods A cross-sectional online survey. Setting and participants The target sample comprised health professionals from the main professional groups supporting patients with chronic progressive illnesses in West Yorkshire and London. …”
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Association of men’s contraceptive knowledge, attitude and behavior with modern contraceptive use: evidence from Nepal demographic health survey 2022 by Vijaya Laxmi Shrestha, Kamala Devi Lamichhane, Sharadha Hamal, Nanda Lal Sapkota, Krishna Man Shrestha

“…This study aims to examine the association of men’s contraceptive knowledge, attitudes, and behaviors (KAB) with the use of modern contraceptives. Methods This study utilized data from the Nepal Demographic and Health Survey 2022, which included a total weighted sample of 2,649 married men aged 15–49 years. …”
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SMART: Structured Missingness Analysis and Reconstruction Technique for credit scoring by Seongil Han, Haemin Jung, Paul D. Yoo

“…Recent advancements have introduced more sophisticated techniques, such as Generative Adversarial Imputation Networks (GAIN), which utilize a generative adversarial network to model data distributions and impute missing values with greater precision than conventional methods. …”
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Potential of Graphic Organizers in Developing Communicative Competence in Learning Russian as a Foreign Language by Sharofat T. Chorieva

“…The study involved 448 respondents, students of grades 9–10 of secondary comprehensive schools with the Uzbek language of instruction in the Tashkent, Namangan and Surkhandarya regions of the Republic of Uzbekistan. Methods. We used the methods of theoretical analysis of scientific literature, as well as the methods of quantitative and qualitative analysis. …”
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Evaluation of clinical, laboratory, radiographical and histopathological characteristics in patients with spinal tuberculosis in the context of HIV infection: An analysis of 52 pat... by J Scherer, M Locketz, S Castelein, R Dunn, M Held, F Thienemann

“…In our cohort, HIV-infected patients with STB were more likely to present with vertebral collapse, and more vertebrae on average were diseased compared with HIV-uninfected patients with STB. …”
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MicroRNA expression profile in isolated circulating tumor cells in colorectal cancer by O. I. Kit, I. A. Novikova, N. N. Timoshkina, D. Yu. Gvaldin, A. A. Pushkin, O. Yu. Kaimakchi, A. A. Maslov, A. V. Shaposhnikov

“…To investigate characteristics of microRNA expression in circulating tumor cells (CTC) of patients with colorectal cancer. Materials and methods. The study included blood samples from 299 patients with colon cancer, stages II (T3–4N0M0), III (T1–4N1–2M0) and IV (T1–4N0–2M1). …”
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Sex differences in the impact of social determinants of health on substance use disorder treatment outcomes by C. Leonardo Jimenez Chavez, MacKenzie R. Peltier, Sherry A. McKee

“…Highlights We examined social determinants of health (SDOH), and substance use disorder (SUD) severity-related predictors of substance use and treatment completion in a national sample of approximately 7 million adults. Women demonstrated more consistent vulnerability across predictors, including unemployment, co-occurring psychiatric disorders, and polysubstance use. …”
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Associations of device-measured physical activity across adolescence with metabolic traits: Prospective cohort study. by Joshua A Bell, Mark Hamer, Rebecca C Richmond, Nicholas J Timpson, David Carslake, George Davey Smith

“…In mutually adjusted models, higher MVPA and sedentary time were oppositely associated with cholesterol and triglycerides in VLDL and HDL particles (MVPA more strongly with glycoprotein acetyls and sedentary time more strongly with amino acids). …”
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A pan-genotypic indirect competitive ELISA for serological detection of pigeon circovirus antibodies by Weifan Wang, Weifan Wang, Sa Xiao, Man Zhang, Jinming Liu, Jianxia Tian, Chuanyu Chang, Yuzhen Li, Yajie Zhang, Fuliang Zhang, Fuliang Zhang, Guiming Li, Guiming Li, Xiaoyuan Yuan, Xiaoyuan Yuan, Wenbin Wang, Wenbin Wang

“…Complementary to PCR test, icELISA enhances the comprehensive detection of PICV in epidemiological studies by offering a more practical and sensitive alternative for field applications. …”
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The association between atherogenic index of plasma and cognitive impairment among older adults in Southern Iran: findings from the Bushehr elderly health program by Mohammad Hossein Eslami, Amin Sedokani, Nekoo Panahi, Farshad Sharifi, Moloud Payab, Mahbube Ebrahimpour, Yasaman Zarinfar, Noushin Fahimfar, Iraj Nabipour, Ramin Heshmat, Bagher Larijani, Afshin Ostovar

“…This study aims to evaluate the association between AIP and cognitive impairment in a sample of older adults in Iran. Methods The study enrolled 2373 individuals (51.5% women) aged more than 60 years participating in the second phase of the Bushehr Elderly Health Program. …”
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Ozone trends in homogenized Umkehr, ozonesonde, and COH overpass records by I. Petropavlovskikh, I. Petropavlovskikh, J. D. Wild, J. D. Wild, K. Abromitis, K. Abromitis, P. Effertz, P. Effertz, K. Miyagawa, L. E. Flynn, E. Maillard Barras, R. Damadeo, G. McConville, G. McConville, B. Johnson, P. Cullis, S. Godin-Beekmann, G. Ancellet, R. Querel, R. Van Malderen, D. Zawada

“…Trends are derived using vertical ozone profiles from NOAA's Dobson network via the Umkehr method (with a recent new homogenization), ozonesondes, and the NOAA COHesive Solar Backscatter Ultraviolet Instrument (SBUV)/Ozone Mapping and Profiler Suite (OMPS) satellite-based record (COH) sampled to match the geographical coordinates of the ground-based stations used in this study. …”
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Prolonged versus single dose in penicillin oral challenge testing: protocols for a pilot and definitive randomised controlled trial (PROSPECTOR studies) by Vito Sabato, Jason Trubiano, Sara Vogrin, Richard Sullivan, Michael Lane, Suran Fernando, Fiona James, Jonathan Grant Peter, Morgan Rose, Amy Legg, Irvin Ng, Ana Copaescu, Elise Mitri, Jack Godsell, Lene Heise Garvey, Philip Li

“…Direct oral penicillin challenge has been demonstrated to be a safe and effective method for the removal of PALs. However, the question of whether a single dose is sufficient to ascertain true allergy status remains unanswered, with some studies suggesting that extended challenges of 3 or more days are superior for the exclusion of delayed immune reactions. …”
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Liver cancer: expression features of hepatitis B antigens by V. A. Tumanskiy, M. D. Zubko

“…People chronically infected with HBV are 20 times more likely to develop liver cancer than uninfected people [1,22,28]. …”
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Modeling Factors Influencing Project Financing Risk by Gholamreza Sharafi, Kiamars Fathi Hafashjani, Faegh Ahmadi

“…Understanding these risk factors and their interplay is paramount for stakeholders involved in project financing endeavors. MethodsTo explore these dynamics, this study employs an objective-oriented approach, leveraging a descriptive-correlational method for data collection. …”
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Pengaruh Penggunaan Media Pembelajaran Interaktif Quizizz terhadap Hasil Belajar Siswa Kelas 10 Program Keahlian DKV SMK Negeri 10 Malang by Krisna Wahyu Saputra, Faizatul Amalia, Khalid Rahman

“…This research focuses more on the use of interactive learning media Quizizz using the Quasy Experimental research method with the type of Non-Equivalent Control Group Design. …”
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Association between stroke and fracture and the mediating role of depression: a cross-sectional study from NHANES 2017 to 2020 by Yuqin Dan, Xuewen Pei, Danghan Xu, Zhaoxi Liu, Yuqi Wang, Meng Yin, Li Li, Gongchang Yu, Gongchang Yu

“…This study aims to clarify the intricate relationships among stroke, depressive symptoms, and fracture risk, potentially informing more holistic clinical strategies.MethodsUtilizing the most recent data from the National Health and Nutrition Examination Survey (NHANES, 2017 to 2020), this study encompassed 4,979 valid samples. …”
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Analysis of clinical features, prognosis and comprehensive therapeutic strategies in 261 patients with limited-stage esophageal small cell carcinoma by LIU Di, NI Jianjiao, ZHAO Kuaile, XIANG Jiaqing, ZHANG Zhen, ZHANG Junhua

“…Survival analysis was performed using the Kaplan-Meier method, and Cox regression was used to analyse factors related to prognosis. …”
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