Risk of Environmental Contamination by Gastrointestinal Parasites in Public Areas of the Central Plateau Microregion of Brazil: A Public Health Concern by Ana Julia de Almeida Martins, Alice Caroline da Silva Rocha, Zara Mariana de Assis-Silva, Guilherme Oliveira Maia, Bruna Samara Alves-Ribeiro, Raiany Borges Duarte, Iago de Sá Moraes, Nicoly Ferreira de Urzedo, Lizandra Fernandes-Silva, Ana Paula Carvalho Gomes, Samara Moreira Felizarda, Mayra Parreira Oliveira, Klaus Casaro Saturnino, Hanstter Hallison Alves Rezende, Rosângela Maria Rodrigues, Dirceu Guilherme de Souza Ramos, Ísis Assis Braga

“…Eggs, cysts, and oocysts were detected using the Willis flotation technique and the Hoffman’s spontaneous sedimentation method. The Hoffman’s analysis revealed that 70.3% of the fecal samples were infected across 91.5% of the sampled areas. …”
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Dental Deposits Are Differentially Associated With Periodontal Conditions and the Number of Teeth in Japanese Community‐Dwelling Individuals: The Nagasaki Islands Study by Masayuki Oohira, Masayasu Kitamura, Kanako Higuchi, Mark Luigi Fabian Capati, Mami Tamai, Saki Ichinose, Yasunori Yamashita, Yukio Ozaki, Eijiro Sakamoto, Yumiko Kawashita, Sakiko Soutome, Takahiro Maeda, Atsushi Kawakami, Toshiyuki Saito, Atsutoshi Yoshimura

“…Greater CI score was significantly associated with a higher BOP ratio (OR = 2.18, 95% CI: 1.47–3.23), deeper PPD (OR = 2.04, 95% CI: 1.22–3.50), and more teeth (OR = 0.13, 95% CI: 0.08–0.23). Conclusions Debris and calculus deposition were associated with more severe periodontal conditions, but calculus deposition was strongly associated with more teeth. …”
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Saliva Has High Sensitivity and Specificity for Detecting SARS-CoV-2 Compared to Nasal Swabs but Exhibits Different Viral Dynamics from Days of Symptom Onset by Tor W. Jensen, Rebecca L. Smith, Joseph T. Walsh

“…<b>Conclusions</b>: In the endemic phase of COVID-19 and for development of new tests, testing methods that are less invasive are more likely to be adopted. …”
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Comprehensive multi-omics analysis of tandem duplicator phenotypes in non-small cell lung cancer by Jie Li, Xinyan Pan, Yanting Bi, Jian Huang, Jun Peng, ChunLing Bai, Jianhong Hou, Yang Chen

“…IntroductionThe Tandem Duplicator Phenotype (TDP) is a prominent genomic metric prevalent in non-small cell lung cancer (NSCLC).MethodsMulti-omics samples including DNA copy number, transcriptomics, somatic single-nucleotide variations, clinical data, and cell-line drug sensitivity from TCGA and CCLE are delved into TDP characteristics.ResultsOur thorough analysis reveals that patients with smaller span sizes TDP have a more intricate genome, moderate pathology, enhanced therapeutic response, favorable prognosis, a more active immune system, and higher drug sensitivity. …”
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Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy by M. M. Zwartkruis, M. G. Elferink, D. Gommers, I. Signoria, L. Blasco-Pérez, M. Costa-Roger, J. van der Sel, I. J. Renkens, J. W. Green, J. V. Kortooms, C. Vermeulen, R. Straver, H. W. M. van Deutekom, J. H. Veldink, F. Asselman, E. F. Tizzano, R. I. Wadman, W. L. van der Pol, G. W. van Haaften, E. J. N. Groen

“…Progress has thus far been limited by methodological constraints. Methods To address this, we developed HapSMA, a method to perform polyploid phasing of the SMN locus to enable copy-specific analysis of SMN and its surrounding genes. …”
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Pulp fiber-based composites with plasticized starch via high-shear mixing by A Eliasson, V Polisetti, M Hedenqvist, A Larsson, T Geiger, G. Nyström, E. Malmström

“…Tensile test revealed that the sorbitol-containing samples had higher strength but lower ductility compared to the glycerol-containing samples. …”
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Contribution of Other Respiratory Viruses During Influenza Epidemic Activity in Catalonia, Spain, 2008–2020 by Nuria Torner, N. Soldevila, L. Basile, M. M. Mosquera, P. de Molina, M. A. Marcos, A. Martínez, M. Jané, A. Domínguez, The Working Group for the Catalan Influenza and Acute Respiratory Infection Sentinel Surveillance Network (PIDIRAC)

“…Of these, 73.7% (4298) of samples were positive for at least one respiratory virus; 79.7% (3425 samples) were positive for the influenza virus (IV), with 3067 samples positive for one IV type, 8 samples showing coinfection with two types of IV, and 350 showing coinfection of IV with more than one virus. …”
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Quantitative SISCOM assessment for epileptogenic zone localization: insights from a multicenter study comparing two software platforms in temporal lobe epilepsy by Carla Oliveira Young, Brunno Machado de Campos, Edna Marina de Souza, Sergio Querino Brunetto, Maria Julia de Oliveira Santos Gualberto, Leonardo Alexandre-Santos, Marcos Geraldo Merichelo de Oliveira, Marina Koutsodontis Machado Alvim, Fernando Cendes, Elba Etchebehere, Lauro Wichert-Ana, Bárbara Juarez Amorim

“…Both SPM and Analyze were concordant with the EZ reference standard in 14 cases (70%), showing no difference in sensitivity between the methods. However, SPM generated smaller, more localized clusters, while Analyze produced larger clusters with broader spatial coverage. …”
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Trial to compare mixed-use (multi-use and single-use) intermittent catheter management with single-use management over 12 months (The MultICath Trial): protocol for a non-inferiori... by Isabel Reading, Jeremy Jones, Gillian Watson, Paul Little, Michael Moore, Carl R May, Suzanne Hagen, Doreen McClurg, Karen Guerrero, Jacqui Prieto, Nina Wilson, Carol Shields, Mandy Fader, Bridget Clancy, Margaret Macaulay, Thomas J Chadwick, Brian S Buckley, Rajvinder Khasriya, Alaa Abouhajar, Catherine P James, Nicola Goudie, Sylvia Dickson, Miriam R Avery, Jackie Broadbridge, Alan Cottenden, Cathy Murphy, Anthony Timoney, Sandra A Wilks

“…Using multi-use catheters as well as single-use ones (mixed-use) could bring benefits (eg, reducing plastic waste and patients never running out of catheters) and offer more choice to users. Evidence is needed that mixed-use is at least as safe and acceptable as using only single-use catheters.Methods The MultICath Trial is a non-inferiority randomised controlled trial involving 578 participants. …”
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A retrospective review of psychosocial correlates of chronic pain in cisgender, transgender, and gender-diverse youth receiving evaluation in interdisciplinary pediatric pain clini... by Crystal Tracy, Mary Lynch Milder, Lindsey Vater, Ann Lagges, Kathleen Lemanek, Sharon Wrona, Elaine Gilbert, Adam T. Hirsh, Megan M. Miller, Kelly Donahue, Morgan Streicher, Amy E. Williams

“…Informed consent was not required or obtained due to the retrospective nature of the study.Results Cisgender patients reported worse pain intensity, whereas TGD patients reported lower quality of life and more internalizing symptoms. In the combined sample, pain intensity was correlated with worse functional disability, poorer quality of life, and more catastrophic thinking. …”
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Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs by Jiang Zhao, Qian Zhang, Cunle Zhu, Wu Yuqi, Guohui Zhang, Qianliang Wang, Xingyou Dong, Benyi Li, Xiangwei Wang

“…Abstract Objectives Bladder cancer (BLCA) is a tumor that affects men more than women. The biological function and prognostic value of androgen-responsive genes (ARGs) in BLCA are currently unknown. …”
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Undergraduate dental students and dentists’ acceptability and knowledge about selective caries tissue removal by Luciana Lourenço Ribeiro Vitor, Eloá Cristina Passucci Ambrosio, Paula Karine Jorge, Natalino Lourenço Neto, Thiago Cruvinel, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira

“…The participants who considered pulp wall moist have approximately eight times more likelihood to choose an invasive treatment (p=0.028). …”
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Gender Differences in Clinical and Biochemical Variables of Patients Affected by Bipolar Disorder by Luigi Piccirilli, Enrico Capuzzi, Francesca Legnani, Martina Di Paolo, Anna Pan, Alessandro Ceresa, Cecilia Maria Esposito, Luisa Cirella, Teresa Surace, Ilaria Tagliabue, Massimo Clerici, Massimiliano Buoli

“…<b>Results:</b> With regard to univariate analyses, women were found to be more susceptible to psychiatric comorbidities (χ² = 12.75, <i>p</i> < 0.01), medical comorbidities (χ² = 45.38, <i>p</i> < 0.01), obesity (χ² = 6.75, <i>p</i> = 0.01) and hypercholesterolemia (χ² = 23.54, <i>p</i> < 0.01), as well as to having more mood episodes in the year prior to hospitalization (t = 5.69, <i>p</i> < 0.01). …”
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Extending gene set variation analysis with a reference dataset to stabilize scores by Lorin Towle-Miller, William Jordan, Alexandre Lockhart, Johannes Freudenburg, Aman Virmani, Mandy Bergquist, Jeffrey Miecznikowski, Will Powley

“…For example, if RNA-seq data was collected on an imbalanced sample (e.g., more disease samples than healthy controls), it would be difficult to discern abnormalities in pathway activity since the gene distributions were estimated on a biased population. …”
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Mental health symptom burden in elite ice hockey players and its association with self-reported concussive events by Mitchell J. Andersson, Göran Kenttä, Emma Claesdotter-Knutsson, Anders Håkansson

“…Female ice hockey players reported higher hazardous alcohol consumption (36.4% AUDIT-C ≥ 4) than another athlete sample and more burnout (19.1%) than the general population. …”
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Male victims, experiences with seeking help from domestic violence agencies over time and across western English-speaking countries by Denise A. Hines, Alexandra Lysova, Emily M. Douglas

“…Results: Men from the victims sample were significantly more likely to seek help compared to male IPV victims from the crowdsourcing sample. …”
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Beliefs and Attitudes towards Mental Illness: Comparative Study between Rural and Urban Male Adolescents in Beni-Suef Governorate by Aziza M. Abozeid, Eman N. Ramadan

“…Results: The median age was 14.0 years in both groups, with more illiterate parents in the rural sample. Significantly adolescents from rural areas were aware of mental illness about two-thirds (66.1%) and had read about it (91.7%). …”
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Genome wide association for addiction: replicated results and comparisons of two analytic approaches. by Tomas Drgon, Ping-Wu Zhang, Catherine Johnson, Donna Walther, Judith Hess, Michelle Nino, George R Uhl

“…We assess convergence between results from these two samples using two related methods that seek clustering of nominally-positive results and assess significance levels with Monte Carlo and permutation approaches. …”
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Socio-economic analysis of the EU citizens’ attitudes toward farmed animal welfare from the 2023 Eurobarometer polling survey by Giorgia Riuzzi, Barbara Contiero, Flaviana Gottardo, Giulio Cozzi, Arzu Peker, Severino Segato

“…These clusters could be further merged into three macro-clusters with two main opposite levels of concern (&gt;80% positive answers) about FAW: concerned about at least 10 questions (74% of the sample); concerned about no more than three questions (6% of the sample); and a third macro-cluster in between concerned about five to seven questions, especially on specific farming practices (20% of the sample). …”
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Truncated gRNA reduces CRISPR/Cas9-mediated off-target rate for MSTN gene knockout in bovines by Zheng-wei ZHOU, Guo-hua CAO, Zhe LI, Xue-jie HAN, Chen LI, Zhen-yu LU, Yu-hang ZHAO, Xue-ling LI

“…This finding will provide more effective gene editing strategy for use of CRISPR/Cas9 technology.…”
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