Association between the HLA-A, HLA-B, HLA-C and HLA-DRB1 gene alleles and Sjögren's syndrome with anti-Ro/SSA and anti-La/SSB autoantibodies production by I. A. Guseva, M. D. Chanyshev, A. V. Torgashina, N. V. Vlasenko, Yu. I. Khvan, E. Yu. Samarkina, M. V. Shabatina, K. F. Khafizov

“…However, such studies have not been conducted in Russia.Objective: to study the association between alleles of the HLA-A, HLA-B, HLA-C and HLA-DRB1 genes and the risk of developing SS and the production of autoantibodies.Material and methods. The study included 80 patients with SS or Sjögren's disease (SD). …”
Get full text

Effects of Xiangshao granules on clinical symptoms and serum hormone levels of menopausal syndrome: a systematic review and meta-analysis of randomized controlled trials by Xing Tang, Chengcheng Wang, Yang Liu, Yisha Xu, Shoujin Dong, Min Dai, Chunmei Li, Yan Zhai, Shoujen Lan, Yeayin Yen, Chao Wang, Congcong Yu

“…In the future, multi-center and large sample randomized controlled trials can be conducted for more key clinical indicators to comprehensively analyze the clinical efficacy and applicability of Xiangshao granules in the treatment of MPS.Systematic review registrationhttps://www.crd.york.ac.uk/, identifier CRD42023405228.…”
Get full text

A preliminary study on developing statistical distribution table of hearing threshold deviation for otologically normal Chinese adults by Linjie WU, Yang LI, Haiying LIU, Anke ZENG, Jinzhe LI, Wei QIU, Hua ZOU, Meng YE, Meibian ZHANG

“…These findings require further validation through expanded sample sizes to more accurately assess the characteristics of hearing thresholds in the Chinese population and their discrepancies with existing standards.…”
Get full text

Household transmission of SARS-CoV-2 in a rural area in South Africa by G Maimela, C E Martin, M Chersich, B Bello, J Mauti, T Bäernighausen, S Kohler, A Almuedo-Riera, S Luchters, S Sawry

“…To explore SARS‐CoV‐2 infection incidence and transmission in rural households in South Africa (SA). Methods. We conducted a prospective household cluster investigation between 13 April and 21 July 2021 in the Matjhabeng subdistrict, a rural area in Free State Province, SA. …”
Get full text

Access to child-feeding counseling service and determinant factors among breastfeeding mothers in Ethiopia: a multilevel complex data analysis of 2019 Ethiopian mini demographic an... by Mohammed Seid Ali, Tewodros Getaneh Alemu, Tadesse Tarik Tamir, Almaz Tefera Gonete, Berhan Tekeba, Enyew Getaneh Mekonen, Masresha Asmare Techane, Belayneh Shetie Workneh, Mulugeta Wassie, Alemneh Tadesse Kassie, Alebachew Ferede Zegeye

“…Therefore, this study was conducted to assess the accessibility of child-feeding counseling services and determinant factors among breastfeeding mothers in Ethiopia. Methods The total weighted samples of 3979 participants were included in this study. …”
Get full text

Age of smartphone access: implications for problematic internet use and online risk behaviors by Patricia Gómez, Abel Nogueira-López, David Liñares, María Angustias Salmerón-Ruiz, Antonio Rial-Boubeta

“…Therefore, the aim of this study was to analyze whether earlier access of children to a smartphone of their own promotes a differential pattern of internet use, with higher percentages of PIU and online risk behaviors. Material and methods: We conducted a cross-sectional study in 31 secondary schools in Galicia (Spain). …”
Get full text

Neuraminidase Antibody Response to Homologous and Drifted Influenza A Viruses After Immunization with Seasonal Influenza Vaccines by Yulia Desheva, Maria Sergeeva, Polina Kudar, Andrey Rekstin, Ekaterina Romanovskaya-Romanko, Vera Krivitskaya, Kira Kudria, Ekaterina Bazhenova, Ekaterina Stepanova, Evelina Krylova, Maria Kurpiaeva, Dmitry Lioznov, Marina Stukova, Irina Kiseleva

“…Evaluation of NA-inhibiting (NI) antibodies in combination with antibodies to hemagglutinin (HA) may enhance research on the antibody response to influenza vaccines. Methods: The study examined 64 pairs of serum samples from patients vaccinated with seasonal inactivated trivalent influenza vaccines (IIVs) in 2018 according to the formula recommended by the World Health Organization (WHO) for the 2018–2019 flu season. …”
Get full text

Evaluation of the effectiveness of combined treatment of coronary heart disease – coronary artery bypass grafting, transplantation of autologous bone marrow mononuclear cells: a ra... by V. V. Komok, N. S. Bunenkov, S. A. Beliy, V. M. Pizin, V. M. Kondratev, A. V. Dulaev, A. E. Kobak, T. S. Maksimova, I. P. Sergienko, E. V. Parusova, L. A. Smirnova, E. V. Babenko, B. V. Afanasev, A. S. Nemkov, G. G. Khubulava

“…However, even though ABMMCs have been studied for more than 10 years, there are no unambiguous data yet on several issues. …”
Get full text

Identification of biomarkers and potential drug targets in DFU based on fundamental experiments and multi-omics joint analysis by Xudong Xin, Xudong Xin, Xudong Xin, Xudong Xin, Haidong Zhou, Song Huang, Wenzhao Zhang, Jiahou Xu, Wei Wang, Jihua Wei, Jihua Wei, Jihua Wei, Jihua Wei, Liqing Li

“…ObjectiveThis study aims to investigate the molecular mechanisms by which quercetin facilitates the treatment of diabetic foot ulcers (DFU).MethodsTranscriptome sequencing datasets for DFU, specifically GSE80178, GSE134431, and GSE147890, along with single-cell dataset GSE165816, were retrieved from the Gene Expression Omnibus (GEO) online database (https://www.ncbi.nlm.nih.gov/geo/). …”
Get full text

Exploring the prevalence and association between nutritional status and asymptomatic malaria in Rwanda among under-5 children: a cross-sectional analysis by Aline Uwimana, Annie Robert, Ayman Ahmed, Hélène Alexiou, Nadine Rujeni, Patrice D. Cani, Jean-Paul Coutelier, Léon Mutesa, Amandine Everard

“…Moreover, the results indicate that malaria was more frequent in children with stunting (OR = 1.85, 95% CI = [1.32; 2.59], p < 0.001). …”
Get full text

Physical, social, and emotional impact on patients with congenital heart disease undergoing cardiac catheterization by Maricel Licht-Ardila, Alexandra Hurtado-Ortiz, Edgar Fabián Manrique-Hernández, Justo José Santiago Peña

“…Objective: To evaluate HRQoL in children with congenital heart disease undergoing cardiac catheterization, analysing its association with clinical and sociodemographic variables in a tertiary care hospital. Materials and methods: We conducted a cross-sectional study in paediatric patients aged 2–18 years undergoing haemodynamic procedures for congenital heart diseases. …”
Get full text

Resistance and Impact Training During Weight Loss Improves Physical Function and Body Composition in Older Adults With Obesity by Jakub Mesinovic, Anoohya Gandham, Mavil May Cervo, Paul Jansons, Costas Glavas, Michael Braude, Juan Pena Rodriguez, Barbora De Courten, Ayse Zengin, Belinda R. Beck, Peter R. Ebeling, David Scott

“…Conclusion HiRIT appears to be safe and more effective than AT for improving gait speed in older adults with obesity undertaking dietary weight loss. …”
Get full text

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational stu... by QiPing Feng, Wei-Qi Wei, Cecilia P Chung, Rebecca T Levinson, Alexandra C Sundermann, Jonathan D Mosley, Lisa Bastarache, Jane F Ferguson, Nancy J Cox, Dan M Roden, Joshua C Denny, MacRae F Linton, Digna R Velez Edwards, C Michael Stein

“…Despite the findings from statin clinical trials and genetic studies, there is little direct evidence implicating low LDL-C concentrations in increased risk of T2DM.<h4>Methods and findings</h4>We used de-identified electronic health records (EHRs) at Vanderbilt University Medical Center to compare the risk of T2DM in a cross-sectional study among individuals with very low (≤60 mg/dl, N = 8,943) and normal (90-130 mg/dl, N = 71,343) LDL-C levels calculated using the Friedewald formula. …”
Get full text

Abstract 129: Endovascular Therapy in Cerebral Venous Thrombosis: Nationwide Insights and Implications for Mortality by Liqi Shu, Elizabeth M. Lee, Piers Klein, Mohamad Abdalkader, Thanh Nguyen, Shadi Yaghi, Thalia Field, Lily Zhou

“…We examined the demographic and clinical correlates of EVT use in CVT and assessed its impact on patient outcomes utilizing a national database. Methods We identified CVT cases from 2015 to 2020 in the National Inpatient Sample, with EVT as the primary exposure. …”
Get full text

Factors associated with concordance of mother-child (6-23 months) dietary diversity in Sub-Saharan Africa. by Meklit Melaku Bezie, Hiwot Altaye Asebe, Angwach Abrham Asnake, Bezawit Melak Fente, Zufan Alamrie Asmare, Alemayehu Kasu Gebrehana, Mamaru Melkam, Beminate Lemma Seifu, Sintayehu Simie Tsega, Yohannes Mekuria Negussie

“…Therefore, we investigated the factors associated with the concordance of mother-child dietary diversity in SSA.<h4>Methods</h4>A community-based cross-sectional study was conducted based on the recent Demographic and Health Surveys (DHS) data of eight Sub-Saharan African countries. …”
Get full text

Associations between airborne pollen, pollen-related allergic rhinitis and blood pressure: A systematic review and meta-analysis by Alexandra Bürgler, Sarah Glick, Axel Luyten, Shihua Shi, Marloes Eeftens

“…We further evaluated which personal characteristics may modify a potential association and identified research gaps. Methods: We searched the PubMed, ScienceDirect, EMBASE, and Web of Science databases and systematically reviewed studies focusing on human populations published between 1 January 1990 and 20 September 2023 that presented data on the association between pollen-related AR or pollen exposure and BP or hypertension. …”
Get full text

Response of yield and yield components of six genotypes of Pinto beans (Phaseolus vulgaris L.) inoculation with Rhizobium phaseoli Khavari *, H. & Shakarami2, Gh. by Hadi khavari, Ghodratolah Shakarami

“…Intensive farming is an agricultural system that uses more than necessary and unbalanced inputs (fertilizers and pesticides), causing major of pressure on the environment. …”
Get full text

The role of adipose-derived stem cells in knee osteoarthritis treatment: insights from a triple-blind clinical study by Simin Sajadi, Mohammad Amin Khadembashiri, Gholamreza Raissi, Mohamad Mehdi Khadembashiri, Korosh Mansouri, Homayoun Hadizadeh-Kharazi, Mohammad Taghi Joghataei, Seyed Pezhman Madani, Bijan Forogh, Sina Parsipour

“…Methods This triple-blind, interventional clinical trial included 20 patients with idiopathic knee OA, meeting the American College of Rheumatology (ACR) criteria. …”
Get full text

New World Primates and Their Human Counterparts Share Diseases That Abound with CEACAM and Other Effector Molecules by Martin Tobi, Daniel Ezekwudo, Benita McVicker, Harvinder Talwar, Laura Kresty, Elizabeth Curran, Ronald Veazey, Peter J. Didier, James Hatfield, Mike Lawson, Sonia M. Najjar

“…It was suggested that the smaller CTT CEA moiety might lack components that facilitate the spread of liver metastasis. Later, using more specific CEA assays and increased numbers of specimens, we were able to show higher CEA serum expression in CTTs than in CMs (632.1 ± 306.1 vs. 81.6 ± 183.6, <i>p</i> < 0.005), with similar differences in the serum samples. …”
Get full text

Optimising insulin use in people living with type 2 diabetes at primary healthcare facilities: The Tshwane Insulin Project by P Rheeder, G Botha, G M Mohlala, O Eales, D van Zyl, P Ngassa Piotie

“…Glucose values decreased over 14 weeks, with approximately one-third of participants having no insulin adjustments, one-third having one adjustment, and one-third having more than one adjustment. The mean (SD) HbA1c level decreased from 12.1% (1.6%) to 8.8% (1.6%) over the 14 weeks in 240 paired samples (p<0.001). …”
Get full text