Metagenomic Analysis Identifies Sex‐Related Gut Microbial Functions and Bacterial Taxa Associated With Skeletal Muscle Mass by Hang A. Park, Joohon Sung, Yoosoo Chang, Seungho Ryu, Kyung Jae Yoon, Hyung‐Lae Kim, Han‐Na Kim

“…ABSTRACT Background This study aimed to explore the association between gut microbiota functional profiles and skeletal muscle mass, focusing on sex‐specific differences in a population under 65 years of age. Methods Stool samples from participants were analysed using metagenomic shotgun sequencing. …”
Get full text

Replacement of fetal calf serum by human serum as supplementation for human fibroblast culture Substituição de soro bovino fetal por soro humano como suplemento para cultura de fib... by César Isaac, Cristiana Nicoli de Mattos, Francinni Mambrine Pires do Rêgo, Larissa Nocchi Cardim, Silvana Cereijido Altran, André Oliveira Paggiaro, Rafael Mamoru Carneiro Tutihashi, Mônica Beatriz Mathor, Marcus Castro Ferreira

“…Human serum could be a safer alternative, especially for clinical application. METHODS: We investigated human serum as a substitute for FCS in human fibroblast culture. …”
Get full text

Mortality and Graft Failure With Medical Management Alone Versus Revascularization After Coronary Angiography Among Kidney Transplant Recipients: A Population-Based Study by Labib I. Faruque, Robert R. Quinn, Pietro Ravani, Tyrone G. Harrison, Brenda Hemmelgarn, Stephen Wilton, Alix Clarke, Matthew T. James, Ngan N. Lam

“…Measurements: The outcomes were all-cause mortality, death-censored graft failure, death with a functioning graft, and all-cause graft failure. Methods: We ascertained baseline characteristics, covariate information, and outcome data from the Alberta Kidney Disease Network (AKDN) and Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) databases. …”
Get full text

Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells by P. Zhou, X. Ma, S. Scalia, D. Toskic, X. Wu, T. Fogaren, Nancy Coady Lyons, Luis del Pozo-Yauner, R.L. Comenzo

“…Therefore, we used heterohybridoma (HH) technology to produce clones making FLC thereby providing tools to study light chain behavior. Methods: Marrow CD138+ cells from patients with multiple myeloma (MM) and polyclonal gammopathy (PG) were selected, fused with B5-6 T cells and cultured in hypoxanthine-aminopterin-thymidine medium (HAT). …”
Get full text

Efficacy and safety of acupuncture for the treatment of insomnia in breast cancer patients: A systematic review and meta-analysis by Yupeng Weng, Xuanrong Ren, Zheyan Zu, Lu Xiao, Min Chen

“…Owing to the limited number of studies included, potential biases of heterogeneous interventions, and methodological weaknesses of long-term follow-up, more high-quality RCTs with large sample sizes should be conducted to evaluate acupuncture treatment.…”
Get full text

M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer by Eva M Garrido-Martin, Toby W P Mellows, James Clarke, Anusha-Preethi Ganesan, Oliver Wood, Angelica Cazaly, Gregory Seumois, Serena J Chee, Aiman Alzetani, Emma V King, Gareth Thomas, Peter S Friedmann, Pandurangan Vijayanand, Tilman Sanchez-Elsner

“…We aimed to investigate the interrelationship of these TAM populations to establish how they modulate the efficacy of the adaptive immune system in early lung cancer.Methods Macrophages from matched lung (non-tumor-associated macrophages (NTAMs)) and tumor samples (TAMs) from resected lung cancers were assessed by bulk and single-cell transcriptomic analysis. …”
Get full text

Problems of adherence to therapy in patients with gout in real clinical practice by Elena V. Shchemeleva, Elena A. Skorodumova

“…To evaluate treatment adherence among patients with gout. Materials and methods. One hundred and thirty-eight patients with gout were examined in the Dzhanelidze Saint Petersburg Research Institute of Emergency Care; 89.9% of them are men and 10.1% are women. …”
Get full text

Pragmatic questionnaire-based evaluation of auditory function in individuals with major neurocognitive disorders and hearing loss in diverse contexts by Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Panagiotis Alexopoulos, Antonios Alexandros Demertzis, Panagiotis Biris, Polychronis Economou, Eric Frison, Piers Dawes, Iracema Leroi

“…The HHIE-8 model was less effective (MSE = 7.740), and the model including HHIE and no demographic data was the least reliable (MSE = 9.220).ConclusionHHIE-S and HHIE-2 combined with demographic data are practical and more efficient tools for assessing hearing loss severity in people with dementia and hearing impairment compared to HHIE, HHIE-S and HHIE-SP in different European countries. …”
Get full text

Hemodynamic Factors Driving Peripheral Chemoreceptor Hypersensitivity: Is Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation a Valuable Human Model? by Maksym Jura, Stanisław Tubek, Jędrzej Reczuch, Rafał Seredyński, Piotr Niewiński, Marcin Protasiewicz, Beata Ponikowska, Bartłomiej Paleczny

“…<b>Materials and Methods:</b> A total of 26 severe AS patients (aged 77 ± 6 y, body mass index: 29.1 ± 5.1 kg/m², left ventricular ejection fraction (LVEF): 50 ± 15%) were subjected to a transient hypoxia test twice: immediately before vs. 1–4 months after TAVI (median follow-up: 95 days). …”
Get full text

Biomechanical Advantages of Sustained Dynamic Compression Over Static Fixation in Subtalar Arthrodesis by Christopher E. Gross MD, Shannon King MS, Ryan Brown, Taylor Filicette, James Johnson PhD, David Safranski PhD

“…Thus, surgeons should consider the use of one or more dynamic devices in either trajectory when optimum biomechanical performance is desired. …”
Get full text

Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study by Jingzhe Guo, Ce Liu, Fang Liu, Erkai Zhou, Runxue Ma, Ling Zhang, Bin Luo

“…This research seeks to contribute significantly to China’s existing tuberculosis prevention and control system.Materials and methodsThis research draws upon publicly available pulmonary tuberculosis (PTB) incidence and mortality statistics from 31 provinces and municipalities of mainland China between 2004 and 2018. …”
Get full text

A prospective outcomes and cost-effective analysis of surgery compared to stereotactic body radiation therapy for stage I non-small cell lung cancer by Andrew Kennedy, Shanna A. Arnold Egloff, Casey Martin, Denis Gilmore, Susan Garwood, Tammy Baxter, David Spigel, Melissa Johnson, David Randolph II, Casey Chollet-Lipscomb, Laurie Cuttino, Eleanor Osborne, Jenifer Marks, Pratik Doshi, Meredith Mattlin, Richard Geer, Dax Kurbegov, Howard Burris III

“…Abstract Background To evaluate long-term outcomes, treatment costs, and quality of life associated with curative treatment of newly diagnosed stage I non-small cell lung cancer (NSCLC), by comparing surgery to stereotactic body radiation therapy (SBRT). Methods Multicenter consecutive prospective study of newly diagnosed stage I NSCLC patients independently assigned surgery or SBRT by a multidisciplinary tumor board, recruited prior to therapy initiation (n = 59). …”
Get full text

Exploración de la relación entre la competencia motriz y el rendimiento físico en niños en edad prees-colar: Un estudio transversal (Exploring the Relationship Between Motor Compet... by Cem Kurt, Umut Canli, Pablo Prieto-González

“…These findings suggest that further research with larger and more diverse samples is needed to better understand the link between motor competence and physical performance in early childhood. …”
Get full text

Implementasi Manajemen Mutu Terpadu di Madrasah Ibtidaiyah by Rohmat Rohmat, Yuslam Yuslam

“…This research uses qualitative research methods using research samples at MIN 1 Banyumas and MI MA Nu 1 Pageraji Banyumas. …”
Get full text

Infective Endocarditis—Predictors of In-Hospital Mortality, 17 Years, Single-Center Experience in Bulgaria by Bistra Dobreva-Yatseva, Fedya Nikolov, Ralitsa Raycheva, Mariya Tokmakova

“…Our goal was to assess clinical outcomes in patients with IE and identify determinants of in-hospital mortality. Material and methods: The analysis was retrospective, single-centered, and comprised 270 patients diagnosed with IE from 2005 to 2021 (median age 65 (51–74), male 177 (65.6%). …”
Get full text

Abstract 022: Acute Kidney Injury in Subarachnoid Hemorrhage: Exploring its Clinical Significance and Prognostic Implications by Galadu Subah, Lee Hecht, Bridget Nolan, Aiden Lui, Anaz Uddin, Christina Ng, Nitesh Damodara, Chirag Gandhi, Fawaz Al‐Mufti

“…Further research and attention to this area are crucial for improving patient outcomes and guiding clinical interventions in this challenging condition. Methods ICD‐10‐CM codes were used to query the National Inpatient Sample (NIS) for patients with AIS between 2010 and 2019. …”
Get full text

Effects of gender affirming hormone therapy with testosterone on renal function of assigned female at birth transgender people: a meta-analysis by Daniele Tienforti, Daniele Tienforti, Luca Spagnolo, Luca Piscitani, Camilla Tonni, Vittoria Donatelli, Vittoria Donatelli, Giuliana Cordeschi, Marco Giorgio Baroni, Arcangelo Barbonetti

“…The eGFR was calculated using the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation, which estimates kidney filtration based on serum creatinine, age, and sex.MethodsA thorough search of MEDLINE, COCHRANE LIBRARY, SCOPUS and WEB OF SCIENCE databases was carried out to identify suitable studies. …”
Get full text

Acupuncture for chronic insomnia disorder: a systematic review with meta-analysis and trial sequential analysis by Yi Yu, Yi Yu, Xinju Li, Zheng Zhu, Zheng Zhu, Yingdong Wang, Yingdong Wang, Qiang Xi, Jiwen Qiu, Yidan Xu, Ruonan Liang, Yi Guo, Mingxing Zhang

“…ObjectiveTo investigate the effect of placebo response to acupuncture on subjective and objective sleep indices in patients with chronic insomnia disorder and to understand the effectiveness of acupuncture in the treatment of chronic insomnia disorder (CID).MethodsA comprehensive search was conducted from the inception of the databases to March 17, 2025, encompassing eight databases. …”
Get full text

Recruitment of Young Gay, Bisexual, and Other Men Who Have Sex With Men for a Web-Based Human Papillomavirus Vaccination Intervention: Differences in Participant Characteristics an... by Daniel J Marshall, Amy L Gower, Mira L Katz, José A Bauermeister, Abigail B Shoben, Paul L Reiter

“…Participants recruited via social media were more likely than those recruited via dating apps to complete follow-up surveys at 3 different timepoints (odds ratios 1.52-2.09, P=.001-.008). …”
Get full text

Does the IL-6/KL-6 ratio distinguish different phenotypes in COVID-19 Acute Respiratory Distress Syndrome? An observational study stemmed from prospectively derived clinical, biolo... by Nicolas Partouche, Myriam Maumy, Thien-Nga Chamaraux-Tran, Frederic Bertrand, Francis Schneider, Nicolas Meyer, Morgane Solis, Samira Fafi-Kremer, Eric Noll, Julien Pottecher

“…Such correlation deserves more in-depth pathophysiological study, at best gathered from a prospective cohort with a larger sample size and histological analysis.…”
Get full text