The Genetic Evolution of DENV2 in the French Territories of the Americas: A Retrospective Study from the 2000s to the 2024 Epidemic, Including a Comparison of Amino Acid Changes wi... by Alisé Lagrave, Antoine Enfissi, Sourakhata Tirera, Magalie Pierre Demar, Jean Jaonasoa, Jean-François Carod, Tsiriniaina Ramavoson, Tiphanie Succo, Luisiane Carvalho, Sophie Devos, Frédérique Dorleans, Lucie Leon, Alain Berlioz-Arthaud, Didier Musso, Raphaëlle Klitting, Xavier de Lamballerie, Anne Lavergne, Dominique Rousset

“…In response, we conducted a retrospective study of the diversity of DENV2 strains circulating in the FTAs from 2000 to 2024. Methods: To this end, we selected DENV2 samples from the collection at the National Research Center for Arboviruses in French Guiana (NRCA-FG) and sequenced them using Oxford Nanopore Technologies (ONT)-based next-generation sequencing (NGS). …”
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Orbital cycle records in shallow unconsolidated sediments: implications for global carbon cycle and hydrate system evolution in deep-sea area sediments of the Qiongdongnan Basin by Yang Dong, Yang Dong, Ren Wang, Ren Wang, Jinqiang Liang, Yulin He, Jinfeng Ren, Wanzhong Shi, Wanzhong Shi, Xiaosong Wei, Xiaosong Wei, Hao Du, Hao Du, Xiangyang Xie, Arthur B. Busbey

“…Cyclostratigraphic analysis of the Quaternary unconsolidated sediments can help identify climate and sea level changes that correspond to orbital cycles and improve our understanding of the dynamic evolution of hydrates.MethodsUsing the natural gamma-ray log data from the deepwater area well W01 in the Qiongdongnan Basin, Milankovitch cycle analysis was conducted to identify the primary astronomical period in W01. …”
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Chinese herbal medicines for rhinosinusitis: a text-mining study with comparisons to contemporary research and clinical guidance by Jing Cui, Brian H. May, Wenmin Lin, Qiulan Luo, Anthony Lin Zhang, Xinfeng Guo, Chuanjian Lu, Yunying Li, Charlie C. Xue

“…Systematic reviews suggest some CHM formulations may be beneficial for the management of this condition. Methods This text mining study used an established methodology to search a database containing the full texts of more than 1,150 classical and pre-modern Chinese medicine books to identify references to disorders similar to rhinosinusitis, and the CHMs used as interventions. …”
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Unique characteristics of tertiary lymphoid structures in kidney clear cell carcinoma: prognostic outcome and comparison with bladder cancer by Tatsuhiko Tsunoda, Kazuhiro Kakimi, Shuji Mikami, Mototsugu Oya, Tsukasa Masuda, Nobuyuki Tanaka, Kimiharu Takamatsu, Kyohei Hakozaki, Ryohei Takahashi, Tadatsugu Anno, Ryohei Kufukihara, Kazunori Shojo, Toshiaki Shinojima, Eriko Aimono, Hiroshi Nishihara, Ryuichi Mizuno

“…Background The aims of this study were (1) to clarify the impact of tertiary lymphoid structure (TLS) status on the outcome and immunogenomic profile of human clear cell renal cell carcinoma (ccRCC) and (2) to determine phenotypic differences in TLSs between different types of genitourinary cancer, that is, urinary ccRCC and bladder cancer.Methods We performed a quantitative immunohistological analysis of ccRCC tissue microarrays and conducted integrated genome mutation analysis by next-generation sequencing and methylation array analysis. …”
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Delivering a national de-adoption programme: a documentary analysis of local commissioning policy compliance with England's Evidence-based Interventions programme (EBI) by Carmel Conefrey, Nicola Farrar, Maeve Coyle, Mike Bell, Jane Blazeby, Christopher Burton, Jenny Donovan, Andy Gibson, Joel Glynn, Tim Jones, Angus McNair, Josie Morley, Amanda Owen-Smith, Ellen Rule, Gail Thornton, Victoria Tucker, Iestyn Williams, William Hollingworth, Leila Rooshenas

“…This study (which is part of the NIHR OLIVIA study, an evaluation of the EBI programme) assessed local commissioning policy compliance with EBI recommendations and identified funding mechanisms employed locally to promote enforcement. Methods A documentary analysis was conducted on a purposive sample of local commissioning policies for each of the 17 EBI surgical procedures. …”
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Eco-friendly pest management in integrated rice-fish farming systems using plant-derived biopesticides to promote sustainable agriculture by Wiratno , I.M. Trisawa, I. Taufik, I. Ardi, L. Thesiana, E. Kusrini, D. Susanti, E.W. Minarni, A. Nurawan, A. Jufri, Sukamto , Y. Apriyana, N. Sutrisna, Y. Surdianto, B. Susanto, U. Susanto

“…No insecticide residues were found in fish, soil, or water samples. Fish survival remained high (more than 90 percent), and rice yields increased by 15 percent compared to conventional practices. …”
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Identification of intratumoral bacteria that enhance breast tumor metastasis by Zachary J. Gerbec, Antonio Serapio-Palacios, Avril Metcalfe-Roach, Zakhar Krekhno, Haggai Bar-Yoseph, Sarah E. Woodward, Jorge Pena-Díaz, Oksana Nemirovsky, Shannon Awrey, Sebastian H. Moreno, Sean Beatty, Esther Kong, Nina Radisavljevic, Mihai Cirstea, Shawn Chafe, Paul C. McDonald, Sam Aparicio, B. Brett Finlay, Shoukat Dedhar

“…We tested for the presence of these bacterial genes in patient tumor samples and found they were more likely to be associated with mortality. …”
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Longitudinal Comparison of Three T-Cell Assays and Three Antibody Assays Against SARS-CoV-2 Following Homologous mRNA-1273/mRNA-1273/mRNA-1273 and Heterologous ChAdOx1/ChAdOx1/BNT1... by Hyeyoung Lee, Geon Young Ko, Jihyun Lee, Hyunjoo Bae, Ji Hyeong Ryu, Jin Jung, Hyunhye Kang, Raeseok Lee, Dong-Gun Lee, Eun-Jee Oh

“…This study compares three T-cell and three antibody assays in two vaccine groups. <b>Methods</b>: This prospective longitudinal cohort study involved 46 naïve healthcare workers: a total of 11 in the homologous mRNA-1273 group (three doses) and 35 in the heterologous ChAd group (two ChAd doses followed by a BNT booster). …”
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Factors associated with death in patients admitted with Ebola virus disease to Ebola Treatment Units in Guinea, Sierra Leone, and Liberia – December 2013 to March 2016 [version 2;... by Ralph W. Jetoh, Ajay M.V. Kumar, Alexandre Delamou, Laura Merson, Prabin Dahal, Gomathi Ramaswamy, Ibrahima Kaba, Benjamin T. Vonhm, Trokon Omarley Yeabah, Anthony D. Harries, Pryanka Relan, Adam C. Levine

“…We used the Ebola data platform of the Infectious Disease Data Observatory (IDDO) to review individual patient records to assess factors associated with death, and particularly whether there were differences between laboratory-confirmed and clinically-suspected cases. Methods This was a cohort study involving analysis of secondary data in the IDDO database. …”
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Comparison of conventional culture and automated blood culture system for microbiologic diagnosis of pleural infection by Young Ho Lee, Min Seo Kang, Jinyoung Yang, Si-Ho Kim, Jae-Hoon Ko, Sun Young Cho, Tae Yeul Kim, Hee Jae Huh, Nam Yong Lee, Cheol-In Kang, Doo Ryeon Chung, Kyong Ran Peck, Kyungmin Huh

“…Non-duplicate patients whose pleural fluid samples were tested using both conventional culture and ABCS (BACT/ALERT 3D and VIRTUO, bioMerieux) from 2001 through 2021 were included. …”
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Adherence to life’s essential 8 is associated with delayed white matter agingResearch in context by Li Feng, Zhenyao Ye, Yezhi Pan, Rozalina G. McCoy, Braxton D. Mitchell, Peter Kochunov, Paul M. Thompson, Jie Chen, Menglu Liang, Thu T. Nguyen, Edmond Shenassa, Yan Li, Travis Canida, Hongjie Ke, Hwiyoung Lee, Song Liu, L. Elliot Hong, Chixiang Chen, David K.Y. Lei, Shuo Chen, Tianzhou Ma

“…This study investigates the relationship between LE8 and white matter brain ageing and evaluates the moderating effects of the APOE4 allele. Methods: This cross-sectional study utilized data from the UK Biobank, including genetic, neuroimaging, and health-related data from touchscreen questionnaires, physical examinations, and biological samples. …”
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Impact of heteroresistance on treatment outcomes of people with drug-resistant TB by R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura

“…METHODS: We used targeted deep sequencing to identify mutations associated with DR-TB and heteroresistance in culture samples of 624 people with DR-TB. …”
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Identification of HLA-B*13:01 allele in leprosy patients with dapsone hypersensitivity syndrome in Ambon, Indonesia by Sri Linuwih Susetyo Wardhani Menaldi, Mufqi Handaru Priyanto, Sandra Widaty, Yunia Irawati, Yulia Ariani Aswin, Dwi Anita Suryandari, Melani Marissa, Iwan Ariawan, Emiliana Kartika, Malika Sabrina Yunifananda, Hok Bing Thio

“…Therefore, this study aims to investigate the association between HLA-B*13:01 and DHS within Ambon and surrounding regions.MethodsThis case-control study included leprosy patients undergoing or having completed MDT therapy in Maluku. …”
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The unintended outcome: a retrospective cross‐sectional study using a urine lateral flow assay to detect ART use reveals non‐disclosure of taking ART in South Africa's public healt... by Nsika Sithole, Indira Govender, Matthew Spinelli, Theresa Smit, Siyabonga Cibane, Mlungisi Zwane, Njabulo Phakathi, Meighan Krows, Busisiwe Nkosi, Janet Seeley, Ruanne V. Barnabas, Mark J. Siedner, Mosa Moshabela, Connie Celum, Alison Grant, Monica Gandhi, Adrienne E. Shapiro

“…If successful, this strategy may reduce duplicative care entries and promote more efficient use of resources.…”
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Gene-environment interactions and colorectal cancer risk: A case-control study on xenobiotic metabolizing enzyme polymorphisms in the Jammu& Kashmir, India population by Gowhar Rashid, Gulzar A. Bhat, Tahseen Bilal Rather, Kulsum Akhter, Ishrat Parveiz, Irfan Maqbool, Syed Nisar Ahmad, Malik Tariq Rasool, Farooq Ahmad Jan, Syed Mudassar

“…The study included 246 histopathologically confirmed colorectal cancer (CRC) cases, and an equal number of matched controls based on age (±5 years), gender, and place of residence. Blood samples were collected for DNA extraction, followed by genotyping of xenobiotic-metabolizing enzyme (XME) genes, including CYP2A13, CYP2A6, and GSTs using standard PCR-RFLP and multiplex PCR methods. …”
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The economic burden of influenza-associated outpatient visits and hospitalizations in China: a retrospective survey by Juan Yang, Mark Jit, Kathy S. Leung, Ya-ming Zheng, Lu-zhao Feng, Li-ping Wang, Eric H. Y. Lau, Joseph T. Wu, Hong-jie Yu

“…There is no information available on the economic burden of influenza-associated outpatient visits and hospitalizations at the national level, even though this kind of information is important for informing national-level immunization policy decision-making. Methods A retrospective telephone survey was conducted in 2013/14 to estimate the direct and indirect costs of seasonal influenza-associated outpatient visits and hospitalizations from a societal perspective. …”
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Comprehensive analysis of single-cell and bulk RNA sequencing data unveils antigen-presenting and processing fibroblasts and establishes a predictive model in gastric cancer by Chenggang Zhang, Fangqi Chen, Jie Li, Yixuan He, Juan Sun, Zicheng Zheng, Guanmo Liu, Yihua Wang, Weiming Kang, Xin Ye

“…However, the predictive value of APPF-related genes (APPFRGs) in the prognosis and tumor immune status of gastric cancer (GC) remains largely unexplored. Methods Bioinformatics analysis was conducted using single-cell and bulk RNA sequencing datasets of GC retrieved from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) databases. …”
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Rise and dine: unraveling breakfast habits among tenth graders - a cross-sectional study among 646 students in the City of Witten, Germany (GeWIT study) by Mohamed Salah Anwar Mohamed, Anwar Mohamed, Nessia Rachma Dianti, Anne-Lisa Heye, Klaus Völkel, Judith Tillmann, Oxana Klassen, Paul Wiesheu, Klaus Weckbecker, Eva Münster

“…This study aimed to assess the prevalence of breakfast skipping on the day of the survey among adolescents in Witten, Germany, and to explore its associations with selected sociodemographic characteristics, health-related behaviours, and self-reported health indicators. Methods Between November 2, 2021, and February 25, 2022, a cross-sectional, survey-based study was conducted among 10th-grade students in all nine municipally managed secondary schools in Witten. …”
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Sex differences in burnout and work-family conflict among Chinese emergency nurses: a cross-sectional study by Dongmei Diao, Dongmei Diao, Dongmei Diao, Xiaoli Chen, Xiaoli Chen, Xiaoli Chen, Luying Zhong, Luying Zhong, Luying Zhong, Hao Zhang, Hao Zhang, Hao Zhang, Jianna Zhang, Jianna Zhang, Jianna Zhang

“…This study aimed to apply sex-specific analyses to investigate the associations between dimensions of burnout and work–family role behavior conflict among Chinese emergency department nurses.MethodsThis was a cross-sectional research. A questionnaire comprising items on demographic characteristics, work–family role behavior conflict, and burnout information, was distributed among emergency department nurses from 30 tertiary hospitals across mainland China, between December 26, 2023, and January 18, 2024.ResultsThis study's sample comprised 1,540 nurses. …”
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Comparison of treatment planning for stereotactic radiosurgery and stereotactic body radiation therapy techniques with 2.5mm and 5mm multileaf collimator (MLC): A pilot study [vers... by Senthil Manikandan, Krishna Sharan, Shirley Lewis, Suresh Sukumar, Umesh V, Srinidhi G Chandraguthi, Shreekripa Rao, Rechal Nisha Dsouza, Sneha Ravichandran

“…However, the study must be extended further with more samples and multiple comparison parameters. …”
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