HIV Incidence and Associated Risk Factors Among Young Men Who Have Sex With Men in Tianjin, China: Retrospective Cohort Study by Yan Guo, Hui Gong, Xiangyu Yan, Xinying Zhang, Tielin Ning, Zhongquan Liu, Long Li, Jie Yang, Liu Li, Changxu Ma, Zhuang Cui, Maohe Yu

“…ObjectiveThis study aimed to investigate the HIV incidence and associated risk factors among YMSM aged 16‐24 years in Tianjin, China. MethodsWe conducted a retrospective cohort study among men who have sex with men aged 16‐24 years from October 2017 to December 2022 through the largest local nongovernmental organization serving men who have sex with men in Tianjin. …”
Get full text

Conveying Equipoise during Recruitment for Clinical Trials: Qualitative Synthesis of Clinicians' Practices across Six Randomised Controlled Trials. by Leila Rooshenas, Daisy Elliott, Julia Wade, Marcus Jepson, Sangeetha Paramasivan, Sean Strong, Caroline Wilson, David Beard, Jane M Blazeby, Alison Birtle, Alison Halliday, Chris A Rogers, Rob Stein, Jenny L Donovan, ACST-2 study group, By-Band-Sleeve study group, Chemorad study group, CSAW study group, Optima prelim study group, POUT study group

“…We aimed to investigate how clinicians conveyed equipoise during RCT recruitment appointments across six RCTs, with a view to (i) identifying practices that supported or hindered equipoise communication and (ii) exploring how clinicians' reported intentions compared with their actual practices.<h4>Methods and findings</h4>Six pragmatic UK-based RCTs were purposefully selected to include several clinical specialties (e.g., oncology, surgery) and types of treatment comparison. …”
Get full text

Potential overtreatment of type 2 diabetes therapy in real clinical practice: Omsk Oblast register data by I. V. Druk, D. I. Snarskaya, O. I. Goroshchenya

“…Foreign studies indicate that a significant proportion of older adults with diabetes are potentially exposed to excessive sugar-lowering therapy.Aims: to study the frequency of excessive decrease in HbA1c in a group of patients with T2DM according to a sample from the regional diabetes register.Materials and methods: A content analysis of the regional register of diabetes mellitus was carried out as of ­December 31, 2019. …”
Get full text

Meta-analysis of integrative medicine in the treatment of irradiation cystitis (中西医结合治疗放射性膀胱炎的Meta分析) by SONG Jiangman (宋江曼), LIU Feifei (刘菲菲), LIAN Xiaojing (廉晓静)

“…Objective　Methods The randomized controlled trials on the treatment of irradiation cystitis by integrated traditional Chinese and western medicine published by PubMed, Cochrane library, CBM, CNKI, VIP and Wanfang Database were searched by computer according to the inclusion criteria. …”
Get full text

Analysis of molecular resistance and associated risk factors in tuberculosis by Zhenzhen Wang, Tengfei Guo, Liyang Xu, Jinwei Liu, Long Li, Junrong Jin, Qing Zhang, Tao Jiang, Zhanqin Zhao, Yun Xue

“…Methods Sputum samples from 25,150 non-duplicate patients attending 10 designated TB medical institutions across Luoyang City and all county and township areas under its jurisdiction from January 2019 to December 2023 were analyzed via fluorescence real-time PCR to detect Mycobacterium tuberculosis complex (MTBC)-positive strains. …”
Get full text

SARS-CoV-2 introductions to the island of Ireland: a phylogenetic and geospatiotemporal study of infection dynamics by Alan M. Rice, Evan P. Troendle, Stephen J. Bridgett, Behnam Firoozi Nejad, Jennifer M. McKinley, The COVID-19 Genomics UK consortium, National SARS-CoV-2 Surveillance & Whole Genome Sequencing (WGS) Programme, Declan T. Bradley, Derek J. Fairley, Connor G. G. Bamford, Timofey Skvortsov, David A. Simpson

“…Using a substantial Irish genomic dataset alongside global data from GISAID, this study aimed to trace the introduction and spread of SARS-CoV-2 across the island. Methods We recursively searched for 29,518 SARS-CoV-2 genome sequences collected in Ireland from March 2020 to June 2022 within the global SARS-CoV-2 phylogenetic tree and identified clusters based on shared last common non-Irish ancestors. …”
Get full text

Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…The study aim was to evaluate the effect of a six-week mindfulness program in women with Long COVID dysautonomia symptoms. Methods: Using a single arm, pre- and posttest design, women aged 18–54 years with Long COVID and orthostatic intolerance suggestive of dysautonomia were recruited from a single center. …”
Get full text

Nursing Complexity and Health Literacy as Determinants of Patient Outcomes: A Prospective One-Year Multicenter Cohort Study by Antonello Cocchieri, Elena Cristofori, Mario Cesare Nurchis, Nursing and Public Health Group, Gianfranco Damiani, Manuele Cesare

“…This study aims to measure nursing complexity and HL in hospitalized patients, examine their interaction, and analyze their impacts on mortality, hospital re-admissions, and ED visits over a one-year follow-up period. <b>Methods:</b> Adult patients from two hospital centers were enrolled, excluding those with stays under two days or cognitive impairments. …”
Get full text

Systemic Immune-Inflammation Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR): A Strong Predictor of Disease Severity in Large-Artery Atherosclerosis (LAA) Stroke Patients by Liu K, Yang L, Liu Y, Zhang Y, Zhu J, Zhang H, He Z

“…This study aimed to verify the predictive value of the clinical parameters such as systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for the severity in Large Artery Atherosclerosis (LAA) stroke patients.Methods: The SII is defined as platelet × (neutrophil count/lymphocyte count), the NLR is defined as neutrophil count/lymphocyte count. …”
Get full text

A Digital Program for Daily Life Management With Endometriosis: Pilot Cohort Study on Symptoms and Quality of Life Among Participants by Zélia Breton, Emilie Stern, Mathilde Pinault, Delphine Lhuillery, Erick Petit, Pierre Panel, Maïa Alexaline

“… BackgroundAfter experiencing symptoms for an average of 7 years before diagnosis, patients with endometriosis are usually left with more questions than answers about managing their symptoms in the absence of a cure. …”
Get full text

Biomechanical Comparison of Two Plantar Lapidus Plating Systems by Felix Werneburg MD, Maria Felsberg MD, Juliane Beschauner MD, Christin Arnold MD, Darius Arbab MD, PhD, Heike Kielstein MD, Alexander Zeh MD, Karl-Stefan Delank MD, Natalia Gutteck MD

“…This study aims to address this gap by evaluating the biomechanical performance of 2 commonly used plantar plate designs. Methods: This study involved a biomechanical analysis of 2 widely used plantar Lapidus plating designs: U-shaped plates and straight-shaped plates. …”
Get full text

Immune Cells as Mediators of Lipidome Influence on Osteoporosis: Evidence from a Mediation Analysis by Jiheng Xiao, Wei Zhou, Jiatai He, Yanbin Zhu, Yingze Zhang, Liming Xiong

“…Exploring lipidomic profiles offers a more comprehensive view of lipid metabolism and may reveal novel genetic links beyond traditional lipid traits. …”
Get full text

Protective effects of curcumin on epileptic rodent models by alleviating oxidative stress and inflammation: a meta-analysis and mechanism exploration by Peng Dai, Lingyu Xu, Peng Zhang, Zheng Liang, Yunhang Chu, Ziqiao Yu, Lin Cao, Peng Sun, Xia Li

“…Subgroup analysis showed that medium and high doses (100–299 mg/kg and ≥300 mg/kg) of curcumin were more stable, but the low dose group (&lt;100 mg/kg) did not conduct in-depth analysis due to insufficient sample size of individual indicators. …”
Get full text

Niveles de actividad física en población adolescente: estudio de caso (Physical activity levels in adolescents: a case study) by Guillermo Oviedo, Josep Sánchez, Rubén Castro, Mar Calvo, Juan Carlos Sevilla, Anna Iglesias, Mirian Guerra

“…In conclusion, we believe very important to seek new strategies and methods to involve more adolescents in the practice of PA, and we believe that PA sessions at school are very important.  …”
Get full text

Relationship between stressors and job burnout: Moderating role of job well-being by Jie WU, Fengmin CHENG, Ruotong YI, Weiqian YU, Chunyan LIU, Mengyu OU

“…Compared to medical staff at general hospitals, medical staff at oncology hospitals are more prone to job burnout, yet few studies in China have focused on job burnout among employees in oncology hospitals.ObjectiveTo propose a hypothetical model in which job well-being moderates the relationship between stressors and occupational burnout, to explore how stressors influence burnout and potential moderating role of job well-being, and to provide better understanding of job burnout and motivate employees based on the double-edge sword effect of stressors.MethodsA cross-sectional survey was conducted in May 2022 at a tertiary oncology specialty hospital in Chongqing, China. …”
Get full text

Knowledge, Attitudes, and Behaviors Related to Dementia Prevention and Caregiving Among Korean Americans (the KIMCHI Project): Pre- and Posttest Evaluation Study by Van Ta Park, Bora Nam, Daren Huang, Stacy W Yun, Nicole Phan, Eun Jeong Lee, Hye-Won Shin

“…Most workshop participants expressed interest in learning more about ADRD-related health topics (186/209, 89%). …”
Get full text

Study of anatomy-diagnostic features of leaves of <i>Cynara scolymus</i> L. grown under the conditions of the Kyrgyz Republic by S. C. Chubakova, N. T. Farmanova, N. V. Bobkova, T. A. Mamatov

“…To study the macro and micromorphological characters of C. scolymus leaves for introduction into medical practice.Materials and methods. Dried leaves of artichoke (Cynara scolymus L.), collected in the flowering phase (June) of 2023, in the Osh region of the Kyrgyz Republic, were used as the object of the study. …”
Get full text

Trends and factors associated with anemia among women of reproductive age in Mali: analysis of data from 2001 to 2018 Mali demographic and health surveys by Ebenezer Kwesi Armah-Ansah, Eugene Budu, Charity Oga-Omenka, Marina Kolosnitsyna

“…Hence, this study examined the prevalence and trends of anemia among women of reproductive age in Mali from 2001 to 2018. Methods The study analyzed datasets from the 2001, 2006, 2012–2013, and 2018 Mali Demographic and Health Surveys. …”
Get full text

High Adherence to Mediterranean Diet and Fish Intake Are Inversely Associated with Depressive Symptoms in Older Women: Findings from the Cross-Sectional NutBrain Study by Federica Prinelli, Silvia Conti, Nithiya Jesuthasan, Elena Perdixi, Matteo Cotta Ramusino, Alfredo Costa, Sara Bernini

“…The main outcome measure was a CES-D score of 16 or more. Statistical analyses were performed using a logistic regression model controlling for potential confounders. …”
Get full text

ADORA2B promotes proliferation and migration in head and neck squamous cell carcinoma and is associated with immune infiltration by Pian Li, Ke-ling Pang, Shuang-jing Chen, Dong Yang, Ai-tao Nai, Gui-cheng He, Zhe Fang, Qiao Yang, Man-bo Cai, Jun-yan He

“…This study aims to elucidate the expression profile, prognostic value, immune modulatory role, and therapeutic potential of ADORA2B in HNSC. Methods Comprehensive bioinformatics analyses were performed using TCGA and GEO datasets to evaluate ADORA2B expression, clinical correlations, and prognostic significance in HNSC. …”
Get full text