Garlic Extracts Nanoliposome as an Enhancer of Bioavailability of ABA and Thiamine Content and as an Antifungal Agent Against <i>Fusarium oxysporum</i> f. sp. <i>pisi</i> Infecting... by Barbara Kutasy, Géza Hegedűs, Márta Kiniczky, József Péter Pallos, Ágnes Nagy, István Pócsi, Klaudia Pákozdi, Máté Kállai, Csaba Weingart, Katalin Andor, Bettina Kovács, Eszter Virág

“…However, effective disease management strategies, particularly the implementation of biological control methods, offer promising approaches for mitigating infection severity and limiting pathogen spread. …”
Get full text

Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece by María Fernanda Skowronek, Santiago Pietroroia, Gabriel de Cola, Mauricio Ramos, Diego Silvera, Gabriela Casanova, Federico Lecumberry, Adriana Cassina, Adriana Cassina, Rossana Sapiro, Rossana Sapiro

“…Ultrastructural analysis further revealed that mitochondria in sperm from infertile men were significantly larger and more irregular in shape compared to those from fertile men. …”
Get full text

Kinetics of Neutralizing Antibody Response Underscores Clinical COVID-19 Progression by Qing Lei, Hongyan Hou, Caizheng Yu, Yandi Zhang, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Zongjie Yao, Hui Fu, Ziyong Sun, Feng Wang, Xionglin Fan

“…The role of nAb during clinical progression of coronavirus disease 2019 (COVID-19) remains little known. Methods. 123 COVID-19 patients during hospitalization in Tongji Hospital were involved in this retrospective study. …”
Get full text

High Neutrophil Alkaline Phosphatase Activity in Adult-Onset Still’s Disease by Nana Ding, Haiye Ren, Jialin Teng, Xiaobing Cheng, Junna Ye, Yutong Su, Hui Shi, Qiongyi Hu, Yue Sun, Jianfen Meng, Huihui Chi, Zhuochao Zhou, Jinchao Jia, Chengde Yang, Hong-Lei Liu

“…Blood samples were collected and smears were prepared, stained, and analyzed to calculate the NAP score. …”
Get full text

The relationship between immigrant status, cultural/racial background, and hypothyroidism among middle-aged and older Canadians: An analysis of Canadian Longitudinal Study on Aging... by ZhiDi Deng, PharmD, Karen M Davison, PhD RD, Michelle Cartier, MA, Andie MacNeil, MA MSW, Esme Fuller-Thomson, PhD

“…We investigated associations between immigration recency, cultural/racial origin, and hypothyroidism. Methods: Using the Canadian Longitudinal Study on Aging (unweighted n = 26,036), analyses were conducted to examine associations between hypothyroidism and sociodemographic factors including immigrant status, immigrants' cultural/racial origin, and health and dietary intake covariates. …”
Get full text

Changes in stigma and population mental health literacy before and after the Covid-19 pandemic: Analyses of repeated cross-sectional studies by Petr Winkler, Benjamin Kunc, Zoe Guerrero, Pavel Mohr, Georg Schomerus, Karolína Mladá

“…We aimed to compare levels of mental health related stigma among the Czech general adult population before and after the Covid-19 pandemic, as well as recognition of own mental health problems, among those members of the general population who screened positively for mental disorders. Methods: We conducted a comprehensive analysis of multiple almost identically designed cross-sectional surveys carried out on representative samples of the non-institutionalized adult population in Czechia in 2017, 2019, and 2022. …”
Get full text

Maternal health inequity in Somalia: A multivariate analysis of poverty and service utilization using nationwide cross-sectional survey data by Asma Mahamoud Abdillahi, Omer Adam Farih, Mustafe Abdillahi Ali, Abdirizak Hassan Abokor, Hodo Abdikarim, Saeed Hassan Mohamed, Awale Ali Omer, Shabcan Mohamed Ali, Abdisalam Hassan Muse

“…Study design: A quantitative, cross-sectional study. Methods: We used data from the 2020 Somalia Health and Demographic Survey (SHDS), a nationwide survey. …”
Get full text

Serum IL-23 levels reflect a myeloid inflammatory signature and predict the response to apremilast in patients with psoriatic arthritis by Maria De Santis, Maria De Santis, Antonio Tonutti, Antonio Tonutti, Natasa Isailovic, Francesca Motta, Francesca Motta, Radu Marian Rivara, Rita Ragusa, Giacomo M. Guidelli, Marta Caprioli, Angela Ceribelli, Angela Ceribelli, Daniela Renna, Nicoletta Luciano, Nicoletta Luciano, Carlo Selmi, Carlo Selmi

“…BackgroundThe phosphodiesterase 4 (PDE4) inhibitor apremilast downregulates the production of IL-23 and other pro-inflammatory cytokines involved in the pathogenesis of psoriatic arthritis (PsA).AimTo investigate the effects of apremilast on the production of cytokines by peripheral blood monocyte-derived macrophages, innate-like lymphocyte cells (ILCs), mucosal-associated invariant T (MAIT) cells, γδ T cells, natural killer (NK) cells, and NKT-like cells from patients with PsA manifesting different clinical responses to the treatment.MethodsPeripheral blood samples were obtained from patients with PsA at baseline and after 1 and 4 months of apremilast therapy (n = 23) and 20 controls with osteoarthritis. …”
Get full text

Assessing mutation-clinical correlations and treatment outcomes in Vietnamese non-small cell lung cancer patients by Hoang-Bac Nguyen, Bang-Suong Nguyen-Thi, Huu-Huy Nguyen, Minh-Khoi Le, Quoc-Trung Lam, Tuan-Anh Nguyen

“…The goal is to identify mutation patterns and their correlations with clinical factors, thereby informing personalized treatment strategies. Materials and methods: A cross-sectional study of 299 NSCLC patients at the University Medical Center, Ho Chi Minh City (2019–2022) recorded demographics, smoking history, and tumor stage. …”
Get full text

Development of a high-sensitivity vertical flow immunoassay for the detection of Rift Valley fever virus by Alexander J. Summers, Haydon J. Hill, Jasmine P. Devadhasan, Jian Gu, Vanessa Berner, Sujata G. Pandit, Marcellene A. Gates-Hollingsworth, Kathryn J. Pflughoeft, Douglas C. Montgomery, Supriya Atta, Tuan Vo-Dinh, David P. AuCoin, Frederic Zenhausern

“…The prototype diagnostic described in this research was shown to be more sensitive than traditional methods, such as lateral flow dipstick tests. …”
Get full text

Bladder cancer microbiome and its association with chemoresponse by Rashida Ginwala, Laura Bukavina, Laura Bukavina, Mohit Sindhani, Erika Nachman, Erika Nachman, Suraj Peri, Jodie Franklin, John Drevik, Sarah Christianson, Daniel M. Geynisman, Alexander Kutikov, Philip H. Abbosh, Philip H. Abbosh

“…Despite the urinary microbiome being one of the most clinically significant microbiomes in human health, it is one of the least well-described.Methods and materialsTo begin to annotate the urinary microbiome present in bladder cancers, we analyzed human genome-filtered sequencing data from the Cancer Genome Atlas (TCGA) from 116 tumors (duplicates from 22 tumors), 22 adjacent normal bladder tissues, and 99 blood samples to classify reads originating from known microbiota. …”
Get full text

Analysis of microstructure properties of Ni-Fe MOFs and their influence on selective recognition of single and binary dye systems by Dan Xu, Xiaolin Cao, Jie Zhou, Zhihao Lin, Jing Wang, Jiatong Han, Ge Chen, Guangyang Liu, Xiaomin Xu, Yanguo Zhang, Donghui Xu

“…In this study, five types of Ni/Fe-MOFs were synthesized via a one-pot solvothermal method by varying the Ni/Fe molar ratio. Their physicochemical structures, surface morphologies, and compositions were characterized through a series of techniques, and their adsorption performances for different dyes were preliminarily investigated. …”
Get full text

Chronobiological Changes in Biochemical Hemorrheological Parameters and Cytokine Levels in the Blood of Diabetic Patients on Hemodialysis: A Cross-Sectional Study by Fernando A. Lima, Juliana S. Monção, Mariana S. Honorio, Mahmi Fujimori, Danielle C. H. França, Aron C. M. Cotrim, Emanuelle C. H. França, Aline C. França-Botelho, Danny Laura G. Fagundes-Triches, Patrícia G. F. Marchi, Adenilda C. Honorio-França, Eduardo L. França

“…<b>Aims:</b> This observational study evaluated gender-based chronobiological changes in biochemical, hemorheological factors, and cytokines in patients with dialysis-dependent diabetic nephropathy. <b>Materials and Methods</b>: A cross-sectional study was conducted in Barra do Garças, Brazil, involving 46 patients with type 2 diabetes mellitus who were on regular hemodialysis. …”
Get full text

Detection of Trypanosoma lewisi from rodents residing in the densely populated residential regions along the coastal areas of Banyuwangi Sub District, Indonesia by April Hari Wardhana, Frenky Laksana Putra, Aditya Yudhana, Dyah Haryuningtyas Sawitri, Ening Wiedosari, Mujiyanto Mujiyanto, Swastiko Priyambodo, Mufasirin Mufasirin, Penny Humaidah Hamid, Yudhi Ratna Nugraheni, Aan Awaludin, Priyono Priyono, Alan Payot Dargantes, Makoto Matsubayashi

“…Aim: The aim of the study was to detect T. lewisi from rodents residing in the densely populated residential regions along the coastal areas of Banyuwangi Sub District. Methods: A total of 169 rodents were captured across three villages of Kampung Mandar, Lateng and Kepatihan, using rat single live traps. …”
Get full text

Effects of previous steroid treatment on ischemic stroke outcomes: a propensity score-matched hospital analysis by Yasser Alatawi, Eman A. Alraddadi, Eman A. Alraddadi, Abdullah A. Alhifany, Faisal E. Alzahrani, Faisal E. Alzahrani, Saud M. Alknawy, Saud M. Alknawy, Nawaf M. Aljohani, Nawaf M. Aljohani, Husun K. Kecheck, Husun K. Kecheck, Alanoud K. Alaslab, Alanoud K. Alaslab, Aser F. Alamri, Aser F. Alamri, Ahmed Aljabri, Daniyah A. Almarghalani, Daniyah A. Almarghalani, Faisal F. Alamri, Faisal F. Alamri

“…Future studies with larger sample sizes and more detailed data on steroid use and stroke outcomes are required. …”
Get full text

Harmonization of multi-center diffusion tensor tractography in neonates with congenital heart disease: Optimizing post-processing and application of ComBat by Benjamin Meyers, Vincent K. Lee, Lauren Dennis, Julia Wallace, Vanessa Schmithorst, Jodie K. Votava-Smith, Vidya Rajagopalan, Elizabeth Herrup, Tracy Baust, Nhu N. Tran, Jill V. Hunter, Daniel J. Licht, J. William Gaynor, Dean B. Andropoulos, Ashok Panigrahy, Rafael Ceschin

“…Advanced brain imaging of neonatal macrostructure and microstructure, which has prognosticating importance, is more frequently being incorporated into multi-center trials of neonatal neuroprotection. …”
Get full text

Slow virologic control but strong immune and metabolic recovery with dolutegravir-anchored therapy in an HIV cohort in Ghana by Mark Appeaning, Edwin Magomere, Alberta Mawulawoe Abotsi, Nana Ama Yeboaa Amoako, Kirk Elorm Kouffie, Becky Ewurama Tetteh, Bridget Nana Darkoa Quist, Christèle Nguepou Tchopba, Gloria Akosua Ansa, Evelyn Yayra Bonney, Peter Kojo Quashie

“…This report evaluates viral load dynamics, immune responses, and organ-level metabolic changes following antiretroviral therapy (ART) initiation. Method We collected blood samples, medical, and demographic data from ART-naïve individuals at baseline and six months post-ART, and from ART-experienced individuals at a single time point. …”
Get full text

Preparation of Magnetic Photocatalyst Fe₃O₄@SiO₂@Fe-TiO₂ and Photocatalytic Degradation Performance of Methyl Orange in Na₂SO... by Li Sun, Zilong Li, Zhigang Yuan, Ying Liu, Shunqi Mei, Fanhe Meng, Xingyu Ouyang, Yi Xiong, Ke Zhang, Zhen Chen

“…In this study, Fe₃O₄@SiO₂@TiO₂ (FS-FT (0 g)) photocatalysts, featuring a magnetic core–shell structure, and Fe-doped Fe₃O₄@SiO₂@Fe-TiO₂ (FS-FT (x g)) photocatalysts, were fabricated via the sol–gel method. Structural and compositional analyses of the processed samples were systematically conducted through X-ray diffraction (XRD), transmission electron microscopy (TEM) with selected area electron diffraction (SAED), surface-sensitive X-ray photoelectron spectroscopy (XPS), and optical property assessment via UV-Vis diffuse reflectance spectroscopy (UV-DRS). …”
Get full text

Analysis of ABCG2 gene rs2231142 single nucleotide polymorphism and risk factors in hyperuricemia by Meiting Liang, Xingxing Liu, Meng Sun, Jun Zhu, Shanshan Yang, FuRong Jing, Jingyi Shen, Yi He, Wujin Chen, Yuping Sun, Yongsheng Li

“…The genotype at the ABCG2 gene rs2231142 locus were determined using the enhanced multiplex ligation detection reaction method. Serum concentrations of UA, glucose, blood urea nitrogen (BUN), creatinine (CREA), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol (LDL-C) were assessed in both groups. …”
Get full text

Efficacy of Jinshui Liujun decoction on chronic obstructive pulmonary disease patients: a systematic review and meta-analysis by Wanqiu Huang, Hui Wang, Di Wu, Lu Zhang, Jiabing Tong, Jiabing Tong, Minghui Yu, Zegeng Li, Zegeng Li, Qinjun Yang, Qinjun Yang

“…Therefore, the exact therapeutic efficacy of JLD has not been fully evaluated.ObjectivesThis study aimed to ascertain the precise therapeutic efficacy of JLD in treating COPD.Data sources and MethodA search of 10 electronic databases was conducted up to 30 November 2024. …”
Get full text