Resistance exercise snacks as a workplace health intervention by Tom Brandt, Christian Thomas Lothar Schwandner, Annette Schmidt

“…Therefore, it was investigated whether RES is an efficient concept for the workplace health promotion (WHP) to facilitate RT in women and improve musculoskeletal fitness. Methods This pilot-study followed a prospective, controlled intervention design. …”
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Case Report: Improvement of functional dyspepsia using eight constitution acupuncture and eight constitution diet – A report of three cases by Nahyun Cho, Nahyun Cho, Younkuk Choi, Younkuk Choi, Heekyung Kim, Heekyung Kim, Heeyoung Moon, Younbyoung Chae, Sungha Kim, Jungtae Leem, Jungtae Leem, Jungtae Leem

“…These findings support the potential use of ECM-based interventions as effective and personalized treatment approaches for FD. More studies with larger sample sizes and standardized tools to assess diet adherence are required to validate these results and explore long-term outcomes.…”
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Increased sputum peripheral helper T cells are associated with the severity of rheumatoid arthritis but not with the severity of airway disease by Eito Yokoi, Keiko Wakahara, Saya Nakamura, Eriko Fukutani, Shuji Asai, Nobunori Takahashi, Nobunori Takahashi, Toshihisa Kojima, Toshihisa Kojima, Shingo Iwano, Satoko Shimada, Toyofumi Fengshi Chen-Yoshikawa, Naozumi Hashimoto, Naozumi Hashimoto, Makoto Ishii

“…However, whether these cells are involved in RA-associated lung and/or airway disease is unknown.MethodsTph cells in sputum were analyzed by flow cytometry and compared with those in synovial fluid and synovial tissue. …”
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Invasive and Non-Invasive Neuromodulation for the Treatment of Substance Use Disorders: A Review of Reviews by Tyler S. Oesterle, Nicholas L. Bormann, Majd Al-Soleiti, Simon Kung, Balwinder Singh, Michele T. McGinnis, Sabrina Correa da Costa, Teresa Rummans, Mohit Chauhan, Juan M. Rojas Cabrera, Sara A. Vettleson-Trutza, Kristen M. Scheitler, Hojin Shin, Kendall H. Lee, Mark S. Gold

“…Conclusions: As novel and more effective therapies for the treatment of SUD are desperately needed, procedural interventional psychiatry holds promise. …”
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Epidemiologic profile of hemoglobinopathies in Benin by Selma Gomez, Adjile Edjide Roukiyath Amoussa, Edwige Dedjinou, Manasse Kakpo, Pélagie Gbédji, Nouhoum Amossou Soulé, Bernice Quenum

“…Methods: The hemoglobin profiles of 2910 study participants were determined by quantitative electrophoresis. …”
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Comparative study of the glucose and trehalose addition on the extenders for goat sperm liquid storage. by Md. Emtiaj Alam, Most. Shorifa Yeasmin, Dipak Kumar Das, Md. Shohidul Islam, Soshe Ahmed, Md. Hamidul Islam, Md. Akhtarul Islam, Md. Mostofa Kamal, Aurangazeb Kabir, Alam Khan, Md. Hakimul Haque, Md. Abdul Masum, Moizur Rahman, Mst. Ishrat Zerin Moni.

“…Objectives: The objective of this study was to assess the effects of varying glucose and trehalose concentrations on tris-citric acid-egg yolk-fructose (TCEF) diluents for the short-term cold storage of goat semen. Materials and Methods: The semen sample was collected, unwashed, and divided into the following groups: control (TCEF without glucose and trehalose), TCEF + glucose (75, 150 mm), and TCEF + trehalose (75, 150 mm). …”
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Dynamics of neutrophil phenotype and function in sickle cell disease by Aafke E. Gaartman, Aafke E. Gaartman, Lydian A. de Ligt, Lydian A. de Ligt, Lydian A. de Ligt, Boukje M. Beuger, Anton T. J. Tool, Martijn Veldthuis, Taco W. Kuijpers, Taco W. Kuijpers, Rob van Zwieten, Bart J. Biemond, Robin van Bruggen, Erfan Nur, Erfan Nur

“…Neutrophil phenotype was more activated in SCD patients compared to non-matched controls. …”
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A nomogram for assisting in diagnosing mouth breathing based on maxillofacial surface electromyographic activity by Minyue Zhao, Amin S. Mohamed, Bo Cheng, Hongfei Li, Gaoli Wang, Lingling Ji, Rui Zou, Fei Wang

“…Abstract Objective A nomogram based on maxillofacial surface electromyographic (sEMG) activities was developed to assist in diagnosing mouth breathing (MB). Methods Differences in maxillofacial sEMG activities between MB and nasal breathing (NB) subjects were compared across a sample of 250 participants to identify MB diagnostic factors, a nomogram was developed to assist in diagnosing MB. …”
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Contextual and individual inequalities of multimorbidity in Brazilian adults: a cross-sectional national-based study by Bruno P Nunes, Tiago N Munhoz, Sanghamitra Pati, Elaine Thumé, Alexandre D P Chiavegatto Filho, Doralice S Cruz Teixeira, Thaynã R Flores, Fabio A Camargo-Figuera, Luiz A Facchini, Sandro R Rodrigues Batista

“…Objectives The study aims to evaluate the magnitude of multimorbidity in Brazilian adults, as well to measure their association with individual and contextual factors stratified by Brazilian states and regions.Methods A national-based cross-sectional study was carried out in 2013 with Brazilian adults. …”
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Patients’, caregivers and clinicians’ perspectives on education and support about methotrexate: survey to 26 European Countries by Cristiano Matos, Polly Livermore, Mariana Ortiz-Piña, Khadija El Aoufy, Kristina Buerki, Agnes Ágoston-Szabó, Darja Batšinskaja, Jana Melicharová, Marie-Louise Karlsson, Karlien Claes, Ana Isabel Rodriguez Vargas, Ellen Moholt, Ane Ludvigsen, Una Martin, Ulrike Erstling, Angela Camon, Ana Pais, Mikaella Konstantinou, Myrto Nikoloudaki, Souzi Makri, Bruno Silva, Cláudia Paiva, Elena Nikiphorou, Andrea Marques, Ricardo J. O. Ferreira

“…Objectives: To assess patients’, carers’, nurses’ and physicians’ perspectives and experiences regarding patient education (PE) and support of Methotrexate (MTX) treatment in Europe. Methods: An international team of researchers and clinicians, including rheumatology nurses, a pharmacist, a rheumatologist, and three patient representatives, developed a survey. …”
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Selective Mapping of Brain COX-1 with [11C]PS13: Pharmacokinetic Evidence from human PET Imaging by Kiana Orangi, Kimiya Batebi, Farnoosh Vosough, Mahdiyeh Nozad Varjovi, Fatemeh Salehian, Sahar Mesbah, Mehrnaz Salahi, Sajjad Hajihosseini, Mohammad Yousef Fazel, Saman Zaman, Reza Hossein Zadeh, Alaleh Alizadeh, Mahsa Asadi Anar, Niloofar Deravi

“…Aspirin showed minimal effect. Given the small sample size (n = 8), further studies with larger cohorts are warranted to confirm these findings and assess pharmacokinetic influences more thoroughly.…”
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Feasibility of calcium hydroxyapatite (Radiesse®) for improving the biomechanical properties of facial burn scars: A pilot study by Mariana del Carmen Radilla-Flores, Erik Agustín Márquez-Gutiérrez, Mario Vélez-Palafox, María Isabel Castrejón-Vázquez, Osiris Cristina Chávez-Flores, Mario Chopin-Doroteo, Maykel González-Torres

“…Objective: To evaluate the potential effects of CaHA injections on the biomechanical properties of facial burn scars and to compare these effects with those of untreated skin. Methods: A prospective longitudinal feasibility study was conducted with 13 patients who had mature facial scars (2–5 years) covering more than 90% of the face, including hypertrophic, atrophic, and/or keloid scars. …”
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INBRX-106: a hexavalent OX40 agonist that drives superior antitumor responses via optimized receptor clustering by William L Redmond, Yoshinobu Koguchi, Melissa J Kasiewicz, Annah S Rolig, Nisha Holay, Bryan Becklund, Anya Polovina, Sae Jeong Ahn, Brendan P Eckelman, Rashi Yadav, Thi Staebler, Noah D Simons, Yaiza Diaz de Durana

“…Clinical pharmacodynamic analysis in blood samples from patients treated with INBRX-106 showed heightened T-cell activation and proliferation, particularly in central and effector memory subsets, validating our preclinical findings.Conclusions Our data establish hexavalent INBRX-106 as a differentiated and more potent OX40 agonist, showcasing its ability to overcome the limitations of conventional bivalent therapies by inducing superior receptor clustering and multimeric engagement. …”
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Investigation of the Protective Effects of Dexmedetomidine, Midazolam, Propofol, and Intralipid on Oxidative Stress and Inflammation in Rats with Lidocaine-Induced Toxicity by Kucun MK, Guler EM, Saracoglu A, Yildirim M, Demirtas C, Serdogan F, Beyaztas H, Aktas S, Kacan M, Gaszynski T, Ratajczyk P, Saracoglu KT

“…Despite an increase in oxidative stress in brain tissue samples across all groups, it was found that all groups exhibited antioxidant protective effects (p < 0.05). …”
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Relationship between personal anxiety and genes associated with eating disorders in women aged 45-64 by V. V. Gafarov, E. A. Gromova, I. V. Gagulin, V. N. Maksimov, A. V. Gafarova

“…To study the possible relationship between personal anxiety and polymorphic variants of genes associated with eating disorders (rs17782313 MC4R, rs1800497 DRD2, rs9939609 FTO) in women aged 45-64 in Novosibirsk.Material and methods. A random representative sample of women aged 45-64 years (n=1074, mean age, 54,27±0,2 years) was examined in 2003-2005 at the Research Institute of Internal and Preventive Medicine, a branch of the Institute of Cytology and Genetics, within the Health, Alcohol and Psychosocial Factors In Eastern Europe (HAPIEE) project. …”
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High salt intake in the Russian population: prevalence, regional aspects, associations with socio-demographic characteristics, risk factors and diseases. Results of epidemiological... by N. S. Karamnova, S. A. Maksimov, A. V. Kapustina, S. A. Shalnova, O. B. Shvabskaya, А. N. Dotsenko, V. A. Kutsenko, Yu. A. Balanova, S. E. Evstifeeva, A. E. Imaeva, M. B. Kotova, G. A. Muromtseva, А. V. Kontsevaya, O. M. Drapkina

“…To study the characteristics of high salt intake in Russian and Moscow populations according to epidemiological studies.Material and methods. Data from representative samples of adult population aged 25-64 years (n=21922, 8372 men and 13550 women) from Russian 13 regions and persons aged &gt;18 years (n=4063, 1662 men and 2401 women) from Moscow were used. …”
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Comparative assessment of line probe assays and targeted next-generation sequencing in drug-resistant tuberculosis diagnosisResearch in context by Giovanna Carpi, Marva Seifert, Andres De la Rossa, Swapna Uplekar, Camilla Rodrigues, Nestani Tukvadze, Shaheed V. Omar, Anita Suresh, Timothy C. Rodwell, Rebecca E. Colman

“…Comparative evaluations of molecular diagnostic assays in high-burden settings are essential for informing clinical decision-making for DR-TB treatment. Methods: The Seq&Treat clinical study previously evaluated the performance of two targeted next-generation sequencing (tNGS) workflows, GenoScreen Deeplex Myc-TB and Oxford Nanopore Technologies Tuberculosis Drug Resistance Test, on direct sediment samples from persons at risk for DR-TB. …”
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PhyloFunc: phylogeny-informed functional distance as a new ecological metric for metaproteomic data analysis by Luman Wang, Caitlin M. A. Simopoulos, Joeselle M. Serrana, Zhibin Ning, Yutong Li, Boyan Sun, Jinhui Yuan, Daniel Figeys, Leyuan Li

“…We further tested a third dataset of complex human gut microbiomes treated with five different drugs to compare PhyloFunc’s performance with other traditional distance methods. PCoA and machine learning-based classification algorithms revealed higher sensitivity of PhyloFunc in microbiome responses to paracetamol. …”
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The preventive effect of sodium-glucose co-transporter-2 inhibitors on atrial fibrillation and atrial flutter in patients with chronic kidney disease: a meta-analysis by Qian Yang, Chen Wang, Wenjing Wang, Yanhong Li, Yi Dang

“…Subgroup analysis based on sample size and follow-up duration showed that SGLT2i reduced the risk of AF in trials with sample size more than 1,000 and follow-up duration longer than 2 years (0.59% vs. 0.80%; RR 0.74, 95% CI 0.55–0.99, P = 0.04). …”
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The association between gut microbiota composition and cardiometabolic parameters in healthy adults by Seyda Silan Okalin, Nazli Arslan, Ebru Demiray Gürbüz, Mine Arayıcı, Nevin Deniz Kırca, Duygu Ozel Demiralp, Didem Dereli-Akdeniz, Pınar Akan, Ayse Aydan Ozkutuk

“…Fecal and blood samples were collected from all participants. Bacterial DNA from fecal samples was extracted, and the full-length 16 S rRNA was amplified. …”
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